4 MB CURRICULUM HANDBOOK 2001-2002 4th Med. Timetable - an Overview Introduction Dear students, This handbook has been designed to help you navigate your way through the 4th medical year course at NUI,Galway. It will be made available to you in both paper and web based versions. Whilst the paper based version will remain unchanged throughout the year, the web based version has the advantage of offering a notice board facility so the changes to the course can be posted there at short notice. We hope to offer this service to you throughout the academic year of 2001/2002. We would welcome your feedback on the timelessness relevance of the notice board. This handbook is divided into subject related sections. Thus there are separate sections for Pathology, Bacteriology etc. Each section includes an outline timetable, lecture schedule, a description of the assessment procedures including past papers. A reading list and a statement of educational aims and objectives. This is the first version of a 4th med handbook covering the entire year. There will be parts of it that could be improved with your suggestions. Thus we would welcome any feedback that you may have regarding the appropriateness, layout and the content of this handbook. Dr. Peter Cantillon Department of Medical Informatics & Medical Education, Clinical Science Institute, NUI,Galway. E-mail: mime@nuigalway.ie 2 Curriculum Map for 4th, 5th & 6th Medical Years : (A Direction Finder) 1st Term (September - December Pathology Bacteriology Med. Informatics Clin. Attachment in Med/Surgery FIFTH MEDICAL 1st Term (September - December Paediatrics Psychiatrics Gen. Practice Ophthalmology Oto-Rhino-Laryngology Obstetrics & Gynaecology 1st Term (September - December Medicine Surgery Clin. Attachment in Medicine/Surgery Radiology/ Anaesthetics Tutorials in Obstetrics & Gynaecology FOURTH MEDICAL YEAR 2nd Term (January - March) Pathology Bacteriology Med. Informatics. Clin. Attachment in Med./Surgery 3rd Term (April - June) Social + Preventive Medicine Forensic Medicine Dermatology Radiology Anaesthetics Legal Medicine Human Rights Medical Ethics. YEAR (7 Week Blocks in major specialities) 2nd Term 3rd Term (January - March) (April - June) Paediatrics Paediatrics Psychiatrics Psychiatrics Gen. Practice Gen. Practice Ophthalmology Ophthalmology Oto-Rhino-Laryngology Oto-Rhino-Laryngology Obstetrics & Gynaecology Obstetrics & Gynaecology SIXTH MEDICAL YEAR 2nd Term (January - March) Medicine Surgery 3rd Term (April - June) Medicine Surgery Clin. Attachment in Medicine/Surgery Clin. Attachment in Medicine/Surgery Tutorials in Obstetrics & Gynaecology Tutorials in Obstetrics & Gynaecology 3 TABLE OF CONTENTS Introduction Curriculum Map ( A Direction Finder) Table of Contents Bacteriology Lecture & Practical Timetables Course Description Course Objectives Reading List Useful Web Sites Student Assessment & Projects Past Examination Papers Contact Details for Departmental Staff Additional Information Medical Informatics & Medical Education Lecture & Practical Timetables Course Description Course Objectives Reading List Useful Web Sites Student Assessment & Projects Past Examination Papers Contact Details for Departmental Staff Additional Information Pathology Lecture & Practical Timetables Course Description Course Objectives Reading List Useful Web Sites Student Assessment & Projects Past Examination Papers Contact Details for Departmental Staff Additional Information Medicine Lecture & Practical Timetables Course Description Course Objectives Reading List Useful Web Sites Student Assessment & Projects Past Examination Papers Contact Details for Departmental Staff Additional Information 4 Page 2 3 4-5 6 7-8 9 9 10 10 11 12-13 14 15 16 17-19 20-22 23 24 24 25 26-38 39 40 41 42-47 48 49 50 51 52-53 54-60 61 62 63 64-66 67 67 68 68 69 70 71 72 TABLE OF CONTENTS (CONT.) Surgery Lecture & Practical Timetables Course Description Course Objectives Reading List Useful Web Sites Student Assessment & Projects Past Examination Papers Contact Details for Departmental Staff Additional Information 5 73 74-76 77 77 78 78 79 80 81 82 DEPARTMENT OF BACTERIOLOGY 6 LECTURE & PRACTICAL TIMETABLES MICHAELMAS TERM Lecture/Practical Lecture Date/Time Tuesday 2.00 - 4.30 p.m. Wednesday 9.0010.00 a.m. Venue Large Lecture Theatre Small Lecture Theatre Lectures will commence on September 18th 2001. Lecture topics listed hereunder may be subject to change. SEPTEMBER OCTOBER NOVEMBER DECEMBER Infection Associated with Anaerobic Bacteria/Practical Virus Classification/Practical Immunology 3 Hepatitis Virus/Practical Bacteriology of Respiratory Tract Tuberculosis/Practical Control of Infection Intrauterine Infection/Practical Herpes Virus, Cold Sores, Shingles, Glandular Fever, Togavirus, Rabies and Related Viral Agents/Practical Enterovirus & Related Viruses Myxoviruses, Influenza, Measles and others/Practical HIV Virus Device related Infections/Practical Parasitology I Parasitology 2/Practical Parasitology 3 Examination (This is part of the 4th Medical Professional Examination). 7 HILARY TERM Lecture Practical Date/Time Tuesday 2.00 - 3.00 p.m. Tuesday 3.00 - 4.30 p.m. Venue Small Lecture Theatre Teaching Laboratory JANUARY Exam Review/Practical Sexually Transmitted Disease Fungal Infection/Practical Infection of the Central Nervous System Compromised Host Revision 1 Revision 2 Group A & B Will have two Practicals in January dates to be assigned. Will have two Tutorials in January dates to be assigned Tutorial - Room 229 Tutorial - Room 346 Groups C & D Group C Group D TOPICS FOR TUTORIALS 1. Gram-Positive Infection 2. Gram-Negative Infection 3. Anaerobe/Wound Infection 4. U.T.I./Sexually Transmitted Infection 8 COURSE DESCRIPTION The Bacteriology course relates to the causes of infectious disease and to the systems available for prevention, diagnosis and treatment of infectious disease. The course also includes basic elements of clinical immunology relating to immune deficiency and allergy. COURSE OBJECTIVES To acquire an understanding of key principles relating to prevention, diagnosis and treatment of infectious disease (bacterial, viral, fungal and parasitic), and key elements of clinical immunology. A clear perspective of what is critically important or urgent in the prevention and management of infectious disease is of greater importance than detailed theoretical knowledge. 9 READING LISTS Author Mandell Title Principles and Practice of Infectious Disease. Useful WWW References 1. The Bacteriology Course Notes are available on-line 2. Susceptibility to Infection See additional web sites in lecture series handout. 10 STUDENT ASSESSMENTS & PROJECTS 3rd Medical Year: End of Hilary Term End of Michaelmas Term Essay 30 marks Exam 30 marks 4th Medical year End of year Written Paper Practical Exam Oral Exam 70 marks 40 marks 30 marks 11 PAST EXAMINATION PAPERS Ollscoil na hEireann, Gaillimh, The National University of Ireland, Galway Summer Examination 1999 FOURTH MEDICAL EXAMINATION (PART 1) BACTERIOLOGY Professor D.J. Jeffries Dr. Geraldine Corbett-Feeney Professor M. Cormican Time allowed: Three hours Answer five questions 1. With respect to Urinary Tract Infection; (a) List the common bacterial pathogens (b) Indicate the kind of specimen required for laboratory diagnosis and the process of laboratory diagnosis (c) List risk factors for Urinary Tract Infection, with particular reference to age groups, gender and anatomical factors. (d) What is asymptomatic bacteriuria? 2. With (a) (b) (c) (d) respect to tuberculosis write short notes on:The organism which causes tuberculosis Control of the spread of tuberculosis The laboratory diagnosis of tuberculosis Describe your understanding of the current state of tuberculosis control in the World. 3. List the most common bacterial agents associated with meningitis and briefly describe the clinical features, laboratory diagnosis and treatment of bacterial meningitis. 4. In the case of each of the following; name the principle virus responsible and write a brief note on the virus and diagnosis of the infection in the clinical laboratory. (a) “Cold sore” (b) Acquired Immunodeficiency Syndrome (c) Influenza (d) Glandular fever (also known as Infectious Mononucleosis) 5. Briefly describe the routine vaccination schedule currently in place in this country and for each vaccine describe the vaccine with particular respect to:(a) Route of administration (b) Nature of the vaccine (e.g. toxoid, live attenuated etc.) 12 6. List the microbial agents (viral and bacterial) which commonly cause acute diarrhoeal disease. Indicate which ones are important in this area at present. In respect of any one of the organisms, describe the route of transmission, laboratory diagnosis and treatment. 13 CONTACT DETAILS Department of Bacteriology Staff and Contact Details. Name Professor Martin Cormican Dr. G. CorbettFeeney Ms. Victoria Buckley, Ms. Mary E.Whelan Ms. Rosanne Rafferty. Title Professor Lecturer Snr. Technician Technician Secretary Email martincormican@tin et.ie Geraldine.Corbett.fe eney@nuigalway.ie victoria.buckley@nu igalway.ie --- 14 Ext. No. 87-4146 87-4410 87-4572 3488 87-4077 ADDITIONAL INFORMATION The Department has for sale a booklet that covers all the topics of the course and is available from the Department on the Second Floor of the Clinical Science Institute. 15 DEPARTMENT OF MEDICAL INFORMATICS & MEDICAL EDUCATION 16 LECTURE & PRACTICAL TIMETABLES Health Informatics (and applied statistics): Course Contents Date 26/9/01 27/9/01 1/10/01 3/10/01 4/10/01 8/10/01 10/10/01 11/10/01 15/10/01 17/10/01 18/10/01 22/10/01 24/10/01 25/10/01 31/10/01 1/11/01 5/11/01 7/11/01 8/11/01 12/11/01 14/11/01 15/11/01 19/11/01 21/11/01 22/11/01 26/11/01 28/11/01 29/11/01 3/12/01 5/12/01 6/12/01 10/12/01 12/12/01 13/12/01 Informatics Lectures Introduction to new course Introduction to Biostatistics Choosing appropriate tests Data types and Central Ten. Dispersion + Distribution Inferential statistics Chi Square 1 Chi Square 2 applications Medical decision making 1 Medical decision making 2 Medical decision making 3 Advanced Internet search Database search 1 Database search 2 Mann Whitney U 1 Mann Whitney U 2 t-test 1 t-test 2 Kruskal - Wallis Correlation 1 Correlation 2 ANOVA 1 ANOVA 2 Odds Ratio Regression Survival analysis Facts and Prejudice Nature - medical knowledge Evidence and scepticism Critical Appraisal 1 Critical Appraisal 2 Critical Appraisal 3 Critical Appraisal 4 Critical Appraisal 5 17 Study Guide What is Informatics Biostatistics Statistical Tests Descriptive Stats 1 Descriptive Stats 2 Inferential statistics?? Chi square guide Chi square guide Diagnostic process Heuristics Bayes Theorem Finding answers Framing questions Using on-line databases Mann Whitney U Mann Whitney U t-test guide t-test guide Non parametric tests Correlation guide Correlation guide ANOVA guide ANOVA guide Odds Ratio and C/I Regression guide Survival guide! Prejudice guide Medical knowledge Scepticism Surveys Aetiology/Prognosis RCTs Screening and Audit Qualitative research Health Informatics: Course Contents (Cont.) Date 7/1/02 9/1/02 10/1/02 14/1/02 16/1/02 17/1/02 21/1/02 23/1/02 24/1/02 28/1/02 30/1/02 31/1/02 Lectures Critical appraisal 7 Patient records Coding patient data Hospital Info. Systems Records in primary care Using info. in practice Decision support systems Telemedicine Imaging in medicine Telediagnosis Virtual environments Informatics and the future 18 Study Guides Using checklists Patient records Coding HIS GP systems How doctors use info Decision support Telemedicine Imaging in medicine Telediagnosis VLEs The future Practicals Medical Informatics Practicals SPSS Introduction Description Descriptive stats Decision making Virtual patients Chi Square SPSS practical Advanced Internet Search Internet/database No Practical No Practical t-Test, Mann U and KW SPSS practical Correlation SPSS practical ANOVA + Odds ratio SPSS practical Regression and survival analysis Excel 2 SPSS practical Telemedicine Graphs and advanced Excel Appraising search findings Appraising using checklists Telemedicine demo The Future “The future” demo Appraisal 1 Appraisal 2 Revision practical Revision practical 19 Dates 1st,2nd and 4th October 8th,9th and 11th October 15th, 16th and 18th Oct. 22nd, 23rd and 25th Oct. 29th, 30th and 2nd Nov. 5th, 6th and 8th Nov. 12th, 13th and 15th Nov. 19th, 20th and 22nd Nov. 26th, 27th and 29th Nov. 3rd, 4th and 6th Dec. 10th, 11th and 13th Dec. 7th, 8th and 10th Jan. 2002 14th, 15th and 17th Jan. 2002 21st, 22nd, and 24th Jan. 2002 COURSE DESCRIPTION MEDICAL INFORMATICS: WHAT IS THE COURSE ABOUT? Medical Informatics and Medical Education Medical Informatics has become an integral part of the medical curriculum at NUI Galway, based on the following premise: “To support health care, life-long learning, education, research and management medical students should be able to at the time of graduation to utilise biomedical and psychosocial information for: formulating problems; arriving at solution strategies; collecting and critiquing and analysing information; taking appropriate action based on findings and communicating/documenting these processes and results. (AAMC 2001) In order that you might achieve this goal we have set you the following learning objectives. These objectives are derived from those set by the AAMC. If you read them you will have an understanding of what this course is about and what you hope to achieve. Basic competencies Your first step is to ensure that you have basic computer literacy. We will assume that you have these basic competencies already. If you are concerned that you may lack some of these skills, contact Ben Kanaragatnam for some one to one or small group tuition. Before you attempt this course you should be able to: Launch a computer application Save work to hard, floppy and network drives Print from a file using both a toolbar shortcut and a print menu Copy files from one drive to another Use standard word processing and spread sheet applications Use e-mail effectively, including sending attachments and graphics To access and navigate the world wide web using a web browser 20 Filter, evaluate, and reconcile information, demonstrating the following: 1. Knowledge of the factors that influence the accuracy and validity of information in general. 2. The ability to discriminate between types of information sources in terms of their format, authority, relevance and availability. 3. The ability to weigh conflicting information from several sources and reconcile the differences. 4. The ability to critically review of published research reports. 5. Knowledge of copyright and intellectual property issues, especially with regard to electronically retrieved materials. Exhibit good information habits. These reflect attitudes that support the effective use of information technology, and include: 1. Using multiple information sources for problem-solving. 2. Maintaining a healthy scepticism about the quality and validity of all information. 3. Making decisions based on evidence, when such is available, rather than opinion. 4. An awareness of the many ways in which information may become lost or corrupted and the need to take appropriate preventative action. 5. The protection and confidentiality of private information obtained from patients, colleagues and others Informatics in the clinical setting It is important that students learn how to acquire information about patients, make clinical decisions based on the available information and record the information appropriately. In order that a medical student is fully prepared for her at clinical role following qualification she should be able to do the following: 1. Interpret clinical data such as laboratory and X-ray reports 2. Understand the limitations of all forms of investigation. 3. Quantify and communicate the degree of certainty associated with specific items of scientific and clinical information. 4. The identify and locate, when possible, the crucial pieces of missing clinical information, and determine when it is appropriate to act on incomplete information. 5. The students should have a sound understanding of how electronic records work and are applied in practice. 6. The students should have a good understanding of how doctors analyse patient data and reach medical decisions. Algorithms, deduction, pattern recognition etc. 7. Integrate verbal and statistical sources of medical knowledge with the facts of a specific clinical case. 8. Demonstrate understanding of the place for a decision support tools into a little practice. 21 9. 10. 11. Demonstrate an understanding of the relative contribution of Make critical use of Decision Support, demonstrating knowledge of the available sources for decisions ranging from textbooks to on-line databases. Formulate a treatment plan expressing the relative certainties of the differential diagnosis. Express the relative risks and benefits of outcomes and treatment options. Communication and Informatics Doctors must learn how to communicate effectively. Students should therefore be able to demonstrate the following: 1. The ability to use software to create visual materials that effectively support all presentations. 2. The ability to create a handout that includes simple graphics and tables for use in teaching or patient education. 3. The ability to collaborate across multiple sites using electronic mail, discussion lists, newsgroups, teleconferencing, and related communication technologies. Medical Informatics – Statistics course 1. The students should demonstrate an understanding of basic numerical and statistical concepts 2. The students should demonstrate an understanding of the difference between descriptive and inferential statistics 3. The students should be able demonstrate proficiency in the basic statistical skills of informatics: a. Ability to appraise and synthesise data b. Ability to analyse data using statistical techniques c. Ability to use computers to report and present findings 4. The students should have a good understanding of observational and experimental study designs. 5. The students should demonstrate a basic understanding of how to conduct an evidence based literature search and how to synthesise findings into a report or review. 22 Medical Informatics: The methods used to deliver the course The medical informatics course uses 4 teaching methods, namely lectures, computer practicals, self paced learning using the WWW and study guides. There are 72 lectures and 26 discreet practicals. The practical sessions have been designed to consolidate the knowledge learned in the lectures. All the lectures (complete with brief explanatory notes), appear in PowerPoint format on the Medical Informatics website. The WWW lectures can be used for revision or to catch up on missed lectures. Each WWW lecture is linked to a study guide. The study guides are designed to guide your learning about the topic in question. They include recommended reading, links to other resources and self test exercises. We recommend 100% attendance at lectures and practicals. {Failure to attend < 75% of all lectures and/or practicals will remove your automatic right to sit the Medical Informatics Spring Examination.} The WWW lectures and study guides have been designed to complement rather than replace the lecture and practical course. Thus a self-paced approach using our WWW resources will not provide an adequate explanation of the fundamental concepts. The course is divided into two related sections. The first is about medical knowledge and information. “How do we as doctors, know what we know?” It examines how medical information is generated, stored and managed. The second section examines the concepts of certainty and precision. It includes epidemiology and statistics. It is essentially about the examination of medical “truth”. 23 READING LISTS 4MB 2000-2001 – READING LIST 1. For critical reading and study design read the appropriate chapters in “How to Read a Paper” by Trisha Greenhalgh: BMJ Publishing 1997 2. For Statistics read the appropriate chapters in “Interpretation and Uses of Medical Statistics” by Leslie E Daly, Geoffrey J Bourke and James McGilvray: Blackwell Scientific Publications 1991 3. For Medical Informatics read “ Medical Informatics…the essentials by F T De Dombal: Butterworth Heinmann, 1996 4. An alternative and more up to date textbook on medical informatics is available at: http://www.mieur.nl/mihandbook/r_3_3/handbook/home.htm 5. Additional reading material may be given to you at lectures and/or posted on the Q drive in the “Handouts Folder” Useful WWW SITES 1. Centre of Medical Informatics- Monash university Melbourne http://www.med.monash.edu.au/informatics/ 2. Medical Informatics short courses-Stanford university- California-U.S.A http://scpd.stanford.edu/smiseries/med_inf.html 3. Medical Informatics links http://www.cs.man.ac.uk/mig/resources/ 4. Best Health Informatics resources http://www.meduniv.lviv.ua/inform/links_inform.html 5. Health Informatics world wide http://www.imbi.uni-freiburg.de/medinf/mi_list.htm 6. The Royal college of Surgeons of Edinburgh http://www.diploma.rcsed.ac.uk/ 24 STUDENT ASSESSMENTS & PROJECTS Health Informatics: Assessment: a) Term tests end of Terms 1 and 2. (Extended Matching MCQ on Informatics and Statistics) b) Evidence Based Case Report to be completed by the 31/1/2002 c) Final MCQ and Practical OSCE exam in February 2002 The Marks in Health Informatics are distributed as follows: EB Case Report Final MCQ OSCE 50 Marks 50 Marks 100 Marks CLINICAL SCIENCES IN STITUTE NUI GALWAY 25 (091) 524411 EXT. 2262 PAST EXAMINATION PAPERS Department of Medical Informatics and Medical Education Fourth Medical Year Examination March 8th 2001-02-20 0930-1130 You must answer all parts of all five questions Each question has several stems indicated by a letter (e.g. a), b) etc.) Some questions are also divided into sections. Please indicate clearly in your answer book which section and or stem of the question you are answering. (e.g. Qu.4, section 2 (b) means your are answering the second stem in section 2 of the 4th question.) Dr Peter Cantillon Dr. David Bullimore Gloria Avalos This is a two-hour examination, which means that you have approximately 24 minutes per question. 26 Question 1. Collecting and interpreting information Section 1. Audit a) b) c) d) 8 Marks Define the term audit Describe in general terms the purpose of audit Describe in a few sentences how audit differs from research Draw a typical audit cycle indicating the key features of the cycle Section 2. Designing an audit 12 Marks Read the following case study. Design an audit to answer the audit question listed at the end of the case study. Five GPs in a group practice in Dublin have read the National Cardiovascular Disease Strategy document and want to audit the quality of cardiovascular disease prevention provided by their practice. They decide to look first at the highest risk group (i.e. patients with existing cardiovascular disease.) They know that both antiplatelet agents and cholesterol lowering drugs have been shown to reduce further cardiovascular events in these high-risk patients. They are also aware that many of the patients are not taking preventative medication. They decide to carry out an audit of the use of antiplatelet agents (aspirin etc.) by patients with established cardiovascular disease. They hope to use the results to plan a strategy for increasing the use of aspirin (or alternative antiplatelet agent) by patients with pre-existing cardiovascular disease. Your task is to design an audit cycle (using the steps that you learned about in your lecture on audit) to answer the audit question above. Explain your reasoning for each step in the audit cycle. ________________________________ Question 2. Finding information using the Internet 20 Marks a) b) c) d) e) f) g) Define the term “Internet” What is an Internet Service Provider? What is an Internet Web Browser? What is a Search Engine? Write short notes on the operation and use of three different types of search engine available for use on the Internet Explain both the meaning and the use of Boolean Logic in Internet searches. Illustrate your answer with examples Explain the difference between Bibliographic and Value-Added medical databases. Write short notes on the role of each type of database in providing information for evidence based practice. Name one example of each type of database 27 Question 3. Screening 20 Marks Write short notes on the following: a) b) c) d) e) f) What is the purpose of screening? List five of the Wilson and Jungner screening criteria Explain the relevance of each of the criteria that you have listed Apply the five criteria that you have listed to the cervical cancer screening programme. Comment on why cervical cancer screening meets or does not meet the Wilson Jungner criteria that you have selected Explain the terms sensitivity and specificity. Explain the terms positive and negative predictive value Question 4 Section 1: Data types 5 Marks State the level of measurement (nominal, ordinal, interval) used in the following questions taken from a study questionnaire. NB. Do not attempt to answer the questionnaire!! You are being asked to state what kind of data (nominal, ordinal, interval) that each question will produce a) How often do you eat fried food? Daily 4-6 times a week 1-3 times a week Less than once a week b) Do you read food labels? Yes No c) What is your weight in kilograms? d) What is your marital status? Married Widowed Divorced Separated Never married 28 e.) Please indicate your agreement or otherwise with the following statements “I think that beef on the bone should be banned” Strongly disagree Disagree No Opinion Agree Strongly agree 29 Section 2: Please write brief answers to the following questions: 10 Marks a) Explain your understanding of when parametric tests should be used? b) How do you define the terms mean, mode and median and standard deviation? c) The Mann Whitney U is a non-parametric alternative to which parametric tests? d) What is the name of the statistical method for comparing three or more means? e) What is the meaning of the following correlation coefficients? a) r = +1 b) r = -1 c) r = 0 Section 3: Skewed distributions 5 Marks a) Draw by hand a distribution, which indicates positive skew. b) Indicate where you think the mean, median and mode might lie on your positively skewed graph 30 Question 5 Section 1: Odds ratio 8 Marks The following are the results of a case control study looking at the association between Coronary Heart Disease (CHD) and cigarette smoking. The results of the Odds Ratio are presented as follows: Table A Smokers NonSmokers CHD 112 88 No CHD 176 224 Odds ratio = 1.62 Confidence Interval = (1.13 <OR< 2.31) p-value = 0.0055 a) Write an interpretation of Table A above b) Write a null hypothesis concerning the above variables. c) Provide an interpretation for each of the three results listed above (i.e. for the odds ratio, the confidence interval and the p-value) d) Explain what is signified by a 95% confidence interval? Section 2: Parametric tests 6 Marks Data was collected from women who suffer from hot flushes. The age of the women in the study was recorded. Look at the two output tables and answer the questions on the next page. Table 1 Hot Flushes Number women of Mean (yrs) age Standard Deviation (yrs) 5.5 3.77 Yes 7 56.6 No 43 58.3 Table 2 a) Why is the equality of variances calculated? b) Do you think that equal variances can be assumed in table 2? Explain your answer with reference to the results. c) Write an interpretation of these results 31 Section 3: 6 Marks A study looking at whether men or women were more likely to have medical cards produced the following results: Medical Card Yes No Count % Count % Total % Gender Male 42 26% 119 74% 161 100% Total Female 91 30% 217 70% 308 100% 133 336 469 a) What type of table is this? b) What type of data is being presented in this table? c) What test would you use to demonstrate whether the difference in medical card ownership between the sexes is significant or not? d) What is the null hypothesis for this test? e) If the p-value of this test were = 0.06, what would you conclude about the null hypothesis. 32 Department of Medical Informatics and Medical Education Fourth Medical Year Examination March 15th 2001 0930-1200 You must answer all parts of all ten questions You must place all your answers in the electronic answer sheet provided Save your completed electronic answer sheet onto both the U drive and one of the floppy discs provided Submit your floppy disc with your backup answer sheet to the invigilator before you leave Ms. Gloria Avalos Dr. David Bullimore Dr. Peter Cantillon Mr. Ben Kanaragatnam This is a 150 minute examination, which means that you have approximately 15 minutes per question. 33 Open Excel 1 worksheet. (20 marks) The data in the worksheet show the distribution of stay in hospital of children under 15 with hypertrophy of tonsils and adenoids with mention of operation in 2 selected hospital groups. (Note: you will have to copy and paste each group to another worksheet before you calculate the mean value for each group) Using the function keys, Auto filter, Copy, Edit, and Paste special commands, a) Calculate the mean duration of stay in days per child in the hospital (include the 2 groups) b) Calculate the mean duration of stay in days per child in the hospital for Group A c) Calculate the mean duration of stay in days per child in the hospital for Group B Write your findings into the appropriate boxes for answer 1 on your answer sheet. 1. Open Excel 2 worksheet (20 marks) Using the data given in the worksheet create a line chart to display Medical devices yearly sales figures (in £millions) from year 1990-1999 at their two offices. a) Select chart sub-type: Line to display trend over time or categories b) Add a chart title: Galway Medical Devices Sales 19901999 c) Label the Y axis: (£m) d) Label the X axis: Year 1990-1999 e) Remove the gridlines f) Add a shadowed legend underneath the chart g) Display the values on the chart Copy and paste the line chart into the text box provided for answer 2 on your answer sheet. Question 3. 1. Breast cancer in men accounts for about 1% of the total breast cancer incidence. There are concerns that environmental and occupational factors may be associated with the aetiology of breast cancer in men. Search the Internet using the search engine “Excite” to find evidence of either environmental or occupational factors associated with breast cancer in men. Write down two environmental factors and list your search strategy in the text box 34 provided. 2. Use the search engine “Google” to find out what the “CONSORT statement” means in relation to the reporting of the results of randomised controlled trials. Write or paste your answer into the text box provided on the answer sheet. 3. Use the Internet to find out the year and the medical journal in which the CONSORT statement was first published 4. Use the Internet to find the names of three British Journals that have endorsed the CONSORT statement Question 4: Site searching and URLs a) Look up the National Centre for Health Statistics in the USA Use the Internet to find answers to the following questions? What were the “crude” and “age adjusted” death rates in the USA in 1998. How many Americans died of firearms injuries in 1998 What were the top 5 causes of death in the USA in 1998. List them in order of frequency b) The final section of question 4 is on your answer sheet. You are asked to identify the constituent parts of a URL or web address. Type in the empty text boxes provided, the information that the highlighted portions of the web address in question tells you. Question 5: Medline Searches Use the PUBMed version of Medline to do this question The National Library of Medicine PubMed Medline site has some definitions of what the term MeSH means. Find one definition. Copy and paste the first two sentences of the definition here: Find the MeSH tree for the term hyperthyroidism. Cut and paste the MeSH tree for Hyperthyroidism and place it in the text box provided on your answer sheet The debate about whether MMR vaccine is linked with autism and crohn’s disease continues to rage. Find 1 article that supports a link and 1 article that attempts to disprove a link between the MMR and autism. Select the relevant articles, place them in the clipboard. When you have assembled one of each copy and paste the 2 references (do not include the abstracts) from the clipboard to the appropriate area on your answer sheet. 35 Question 6: Medline searches using the OVID interface Use the OVID Medline available from the library for this question. Dr F B Hannon published two papers over the past decade. Copy and Paste both references (no abstracts please) onto your answer sheet. How many articles on Kaposis sarcoma has RH Phillips, a coauthor in the earlier of the two papers published since 1993 How many articles published between 1997 and 2001 mention Galway in either their titles or abstracts. How many articles published between 1993 and 2001 mention Galway in either their titles or abstracts. For all statistics questions open dataset - SPSS Exam This data was collected from 62 patients who have or had stomach cancer. Please remember this is FAKE data. Use the application SPSS to answer the following questions. Question 7: Chi-Square 20 Marks Looking at the data you may wonder whether there is an association between gender (gender) and stomach cancer (stomach), the first task is to run an analysis of Chi-Square. Steps 1. ANALYZE 2. DESCRIPTIVE STATISTICS 3. CROSSTABS Please use the variables Gender and Stomach Cancer (stomach) a) Write a brief interpretation of the results from the contingency table b) Write an interpretation of the results from the “Chi-square test table”, this time include p-values, remember to include the test that you use c) Are the Chi-Square assumptions violated? Explain your answer? d) If assumptions were violated which test could be use instead? Copy and Paste the output from SPSS and answer all the above questions in the electronic sheet. 36 Question 8: 20 Marks Choose the appropriate test to find the difference in the mean rank between two non-parametric variables “Gradetum” Grade of Tumour (grade1, grade2, grade3, grade4) and “Gender” (male and female) a) Write an interpretation of the results Express the difference between the two groups in terms of ranking Is the difference significant? b) The Mann Whitney U is a non-parametric test with two groups, which non-parametric test will you use for more than two groups? Copy and Paste the output from SPSS and answer all the above questions in the electronic sheet. Question 9 ANOVA 20 Marks This time we are looking for the mean difference between the three different treatments of stomach cancer “Treatmen” according to age “Age”, please use ANOVA Steps 1. ANALYZE 2. COMPARE MEANS 3. One-Way-ANOVA a) Why do you need to check the Levene’s table of results? What decision will you make if p>0.05 What will be your decision if p<0.05 b) Write an interpretation of the results. Include comments on the following: What is the p-value? Is there a difference between means? If yes, can you tell in which group the significant difference is? c) When would you need to use a Post Hoc test? f) Using the Post Hoc test can you tell in which groups the mean differs significantly from the others? Copy and Paste the output from SPSS and answer all the above questions in the electronic sheet. 37 Question 10: Correlation 20 Marks We need to know if there is a relationship between patients age “age” and the size of tumour “tumoursz” a) Write the null hypothesis b) Make a scatter diagram, what does the graph tell you? Steps 1. GRAPHS 2. SCATTER Please select the appropriate test for this type of data. (You have the option to select either Pearson’s or Spearman’s.) In order to measure the strength of the correlation, you need to analyse the data 3. ANALYZE 4. CORRELATE 5. BIVARIATE c) Look at the r value and p-value and write an interpretation of results, please include the direction and the strength of the relationship. Copy and Paste the output from SPSS and answer all the above questions in the electronic sheet. 38 CONTACT DETAILS Department of Medical Informatics Staff and contact details Staff member Gloria Avalos Peter Cantillon Ben Kanagaratnam Maura Mhic Iomhair Course Bio Statistics Health Informatics Practical training Lecture and Pract. coord. E-mail gloria.avalos@nuigalway. ie peter.cantillon@nuigalw ay.ie benjamin.kanagaratnam @nuigalway.ie Maura.maciomhair@nui galway.ie 39 Extension 2722 2262 3016 3274 ADDITIONAL INFORMATION Attendance We expect that students will attend at least 75% of all our practicals and lectures. Failure to do so will mean that the student in question may not qualify to sit their 4th MB examination in medical informatics. Student Support If you are having difficulties with the volume of work in 3rd/4th med., or are experiencing problems which are affecting your ability to work, please take the opportunity to talk to a member of our staff at your earliest convenience. We can offer a lot of help with time management, study skills, work planning. We can also direct you to the appropriate support should you have an emotional or physical health problem. 40 DEPARTMENT OF PATHOLOGY 41 LECTURE & PRACTICAL TIMETABLES The class will be divided into Groups A and B for both Practical and MCQ Examination Purposes. Your designated group is as follows: THE CLASS WILL BE DIVIDED INTO GROUPS A AND B FOR BOTH PRACTICAL AND M.C.Q. EXAMINATION PURPOSES. YOUR DESIGNATED GROUP IS AS FOLLOWS. GROUP A GROUP B ABD, Rahman S.M.BT ABDUL, Aziz Mardiana ABDUL, Jauwad, Hend Ahmad Rifai, Bin M.F. Ala, Nazneen K Allen, Nicholas Mark Anak, Christopher, B.T. Beatty, Sharon Ann Benton, Aoife Danielle Binti, Ahmad Termizi, M.S. Bolkim, Darwina Binti Browne, Ann Michelle Burke, Aine Carol Burke, Thomas Ruaidhri Cafferty, Rachel O.E. Cairns, Ciarin Aine Carney, Olivia Mary Cawley, Derek Thomas Dinizulu, Habana Donnelly, Catherine Mary Gallagher, Margaret Maria Gannon, Paul Anthony J Gaolebale, P.Andrew Harrison, Michael Hawkins, Finn J Hegarty, Maeve Kavanagh, Anna H Kelly, Yvonne J Kemple, Peter John Kerin, Emmet Gerard Khanji, Mohmed Yunus Kieran, Elaine Marie Killeen, Martina Mary Kyne, Fiona Mary Lally, Gillian Mary Larkin, Caroline Marie Liu, Hsien TZO Lynch, Deirdre Martina Lynch, Maeve Fahy McHale, Sabrina Marie McMonagle, Caroline A Madigan, Nicholas Niall Makgasa, Moneimang Mat Rani Ghani, M Y Modongo, Chawangwe Mohd Abdullah, A.B. Moloney, Patrick D Mulkerrins, Lorraine G Murphy, Lisa Christine Neylon, Mary Antoinette Ni Chonchubair, Caitlin M. O’Brien, Niall Anthony O’Gorman, Joanne Marie O’Grady Michael O’Mahony, Matthias M O’Malley, Declan O’Malley, Grainne Marie O’Neill, Lorraine Roche, Kate Tunney Saidha, Shiv Sainal, Faridatul Amal Samat, Muttwqillah N.A. Tully, John Gerard Walsh, Sinead Mary Wauchope, Susanne Yarlagadda, Radhesh 42 4th Medical Year Systematic Pathology Teaching Programme Michaelmas Term SYSTEMIC PATHOLOGY TEACHING PROGRAMME MICHAELMAS TERM 2000 LECTURES: SMALL LECTURE THEATRE 2.00p.m. - 3.00p.m. Monday 9.00a.m. - 10.00a.m. Tuesday 12.00noon - 1.00p.m. Wednesday PRACTICALS: 3.00p.m. - 4.30p.m. Monday 10.00a.m. - 11.00a.m. Tuesday DAY Monday DATE Sept. 24th Tuesday Sept. 25th Wednesday Thursday Sept. 26th Sept. 27th Monday Oct. 1st Tuesday Oct. 2nd Wednesday Oct. 3rd Monday Oct. 8th Tuesday Oct. 9th Wednesday Monday Oct. 10th Oct. 15th Tuesday Oct. 16th Wednesday Thursday Monday Oct. 17th Oct. 18th Oct. 22nd Tuesday Oct. 23rd TOPIC Tumours of Oesophagus and Stomach Peptic Ulceration of Stomach, NO LECTURE M.C.Q. RESPORATORY TRACT Pathology of Small bowel Pathology of Large bowel Inflammatory Bowel Disease Alcoholic Liver Disease Viral Hepatitis/Liver Enzymes Cirrhosis Gall bladder Disease and Tumours Disease of the Pancreas NO LECTURE M.C.Q. - G.I.T. Disease of the Glomeruli I Disease of the 43 Duod Wednesday Oct. Monday Tuesday Oct. 29th Oct. 30th Wednesday Thursday Oct. 31st Nov. 1st Monday Tuesday Wednesday Monday Tuesday Wednesday Monday Tuesday Wednesday Monday Tuesday Monday Nov. Nov Nov. Nov. Nov. Nov. Nov. Nov. Nov. Nov. Nov. Dec. 5th 6th 7th 12th 13th 14th 19th 20th 21st 26th 27th 3rd Tuesday Wednesday Monday Tuesday Wednesday Thursday Dec. Dec. Dec. Dec. Dec. Dec. 4th 5th 10th 11th 12th 13th Monday Tuesday Jan. 7th Jan. 8th Wednesday Thursday Jan. 9th Jan. 10th Monday Tuesday Wednesday Monday Tuesday Wednesday Jan. Jan. Jan. Jan. Jan. Jan. Glomeruli II Disease of the Prostate/Tumour Markers (2 hour lecture 11.00a.m. - 1.00 p.m.) BANK HOLIDAY Tumours of Kidney and of the Urethelium. NO LECTURE M.C.Q. - BILARY TRACT Pyelonephritis Haematology Haematology Haematology Haematology Haematology Haematology Haematology Haematology Haematology Haematology Histopathology of Lymphoma Uterus/Cervix Ovaries Breast Testis NO LECTURE M.C.Q. - KIDNEY 24th Skin Rheumatoid Disease/Osteoarthritis NO LECTURE M.C.Q. HAEMATOLOGY Meningitis Trauma Stroke Thyroid Adrenal Parathyroid Gland/Calcium metabolism 14th 15th 16th 21st 22nd 23rd 44 March 1st Week - 4th Medical Pathology Examination AUTOPSY ROTA Students in each group should attend Autopsies on designated weeks including weekends. Week beginning 30/04/01 ABD, Rahman S.M.BT ABDUL, Aziz Mardiana ABDUL, Jauwad, Hend Ahmad Rifai, Bin M.F. Ala, Nazneen K Allen, Nicholas Mark Anak, Christopher, B.T. Week beginning 15/10/01 Liu, Hsien TZO Lynch, Deirdre Martina Lynch, Maeve Fahy McHale, Sabrina Marie McMonagle, Caroline A Madigan, Nicholas Niall Week beginning 07/05/01 Beatty, Sharon Ann Binti, Ahmad Termizi, M.S. Benton, Aoife Danielle Bolkin, Darwina Binti Browne, Ann Michelle Week beginning 22/10/01 Makgasa, Moneimang Mat Rani Ghani, M.Y. Modongo, Chawangwa Mohd Abdullah, A.B. Moloney, Patrick D. Mulkerrins, Lorraine G. Week beginning 14/05/01 Burke, Aine Carol Burke, Thomas Ruaidhri Cafferty, Rachel O.E. Cairns, Ciarin Aine Carney, Olivia Mary Cawley, Derek Thomas Week beginning 20/10/01 Murphy, Lisa Christine Neylon, Mary Antoinette Ni Chonchubhair, Caitlin M O’Brien, Niall Anthony O’Gorman, Joanne Marie O’Grady, Michael Week beginning 21/05/01 Dinizulu, Habana Donnelly, Catherine Mary Gallagher, Margaret Maria Gannon, Paul Anthony J. Gaolebale, P. Andrew Harrison, Michael Week beginning 05/11/01 O’Mahony, Matthias M. O’Malley, Declan O’Malley, Grainne Marie O’Neill, Lorraine Roche, Kate Tunney Saidha, Shev Week beginning 01/10/01 Hawkins, Finn J Hegarty, Maeve Kavanagh, Anna H Kelly, Yvonne J Kemple, Peter John Kerin, Emmet Gerard Week beginning 12/11/01 Sainal, Faridatul Amal Samat, Muttwqillah N.A. Tully, John Gerard Walsh, Sinead Mary Wauchope, Susanne Yarlagadda, Radhesh Week beginning 08/10/01 Khanji, Mohmed Yunus Kieran, Elaine Marie Killeen, Martina Mary Kyne, Fiona Mary Lally, Gillian Mary Larkin, Caroline Marie 45 Computer Sessions The computer suite is located on the second floor of the building. You must be registered with Computer Services before you can use this suite. Check on the door of the suite for times that allow you free access to a terminal. There are many websites that have pathology teaching material available. One of the best is Webpath which is on the server. It contains a very comprehensive selection of gross and microscopic images. In addition it includes mini tutorials and over 1,600 MCQ questions. You will find this an invaluable teaching aid to your Pathology course. Also there are five P.C.s located in the room just off the library. These P.C.s are the property of the Pathology Department and you have exclusive right to access to them. Each terminal has a disc player which allows you to learn Pathology by means of the ‘Slice of Life’ laser discs. The C.D’s ‘Immunology and the Dynamic Cell’ are also available on the server. 46 ATTACHMENT DETAILS See Above. 47 COURSE DESCRIPTION Pathology is the scientific study of the mechanisms of disease, including the changes that occur in tissues as viewed by the naked eye (i.e. at autopsy), the light microscope and the electron microscope level. Abnormalities detected by the above means are observed, documented, photographed, collated and integrated with the patients clinical history and radiology to make a definitive tissue diagnosis of disease. The Pathology Department consists of both an academic and a diagnostic division. The academic department is centred on the ground floor, rooms 107, 115, 116 and 117 of the Clinical Science Institute. Room 107 is the teaching laboratory where one half o the practical session is held. The second half is held in the Pathology museum which is located on the second floor of the building. The museum has many rare and unique specimens of various diseases collected over the years and which are an invaluable teaching aid to the students. The diagnostic arm of the Pathology Department is located in the laboratory complex to the back of the main hospital. The post-mortem suite is located to the right as you enter the main door of the laboratory complex. Students must attend a minimum of 6 autopsies during the academic year. Check the autopsy rota to see which week you have been assigned. You will find an autopsy card in this booklet. Please ensure that the attending Consultant signs your card as this confirms your attendance. Your autopsy card may be handed into the Pathology Department before your final examination. Check the Pathology notice board daily to see if there is a post mortem on that day. The lecture list and any amendments to that list will also be posted on the notice board. Attendance at lectures and practicals is monitored. There is now in place a new 75% attendance rule. You must notify the Department of any absences from lectures, practicals and MCQs. Sick certificates are necessary to account for absence from lectures, assessments and examinations. They are handed directly to Professor Connolly or Ms. Laura Moran in the Pathology Department. If you are leaving the course to do a B.Sc., an Erasmus programme or taking a year off, please inform the Pathology Department of your intention to do so. Please feel free to contact the Department at any time during the academic year if you have any queries or problems. 48 COURSE OBJECTIVES The course objective is to teach Theoretical and Applied Pathology at a level suitable for a 4th year medical student who is staring to see disease processes in the living patient at the bedside for the first time. The medical student must be able to integrate and comprehend in a holistic fashion, the clinical signs and symptoms in the sick patient with the pathologic process, he sees in a pathologic specimen, either by the naked eye appearance or down the microscope. It is expected that by the end of the academic year, the student will be able to do this in a meaningful way so that he/she can make a reasonable attempt at making an integrated diagnosis from clinical, pathologic and radiological data. The student is expected to attend autopsies and learn about diseases and why they cause mortality. The student will be given specimens to examine and will be expected to make a diagnosis, or give a clear differential diagnosis. The student will also be expected to be able to write an essay on the pathology of common diseases for the 4th medical examination. 49 READING LISTS Reading List All of these textbooks are excellent. Robbins Pathologic Basis of Disease is recommended for all students who wish to have one main book to cover the Mechanisms of Disease course and Systemic Pathology. This is an excellent book. It is very comprehensive and it covers the course well. It is suggested that students also use the Pocket companion for revision purposes. For the pathology practicals Wheater's Basic Histopathology is excellent. Recommend: 1. Robbins Pathologic Basis of Disease by Cotran R.S., Kumar V., Collins T. Sixth Edition 2. General and Systemic Pathology by Underwood J.C.E. Second Edition 3. Cells, Tissues and Diseases. Principles of General Pathology by Manjno G., Joris I. 4. Wheaters Basic Pathology by Burkitt H.G., Stevens A., Lowe J.S., Young B. Third Edition. 5. Pocket Companion to Robbins. Pathologic Basis of Disease by Robbins S.L., Cotran R.S., Kumar V. Fifth Edition. Reference Books 1. Anderson's Pathology by Damjanov I., Linder J. Tenth Edition 1997 Volumes I and II 2. Walter and Israel General Pathology by Walter J.B., Talbot I.C. Seventh Edition, 1998 50 3. Immunology by Janway-Travers Third Edition, 1997 Useful WWW SITES http://www.medlib.med.utah.edu/Webpath/webpath.html This website is already on the College server – CENTRAL C.D.’s http://worldmall.com/erf/autopsy.hem. http://www.medscape.com http://www.gen.emory.edu/medweb/Medweb.pathology.htlm http://www.med.umich.edu http://www.Pathology.Washington.edu http://pathweb.UCHC.edu http://www.med.harvard.edu/AANLIB/home.html Google Metacrawler Web Path www.webpath.com p.s. If you find any good Pathology websites please let us know!. 51 STUDENT ASSESSMENTS & PROJECTS Practical exam The class will be divided into three groups. There will be 30 spots comprising histology slides, museum pots and wet specimens. 5 spots will be allocated to Haematology. There is one mark per spot correctly identified. The exam will be held in the Teaching Laboratory Room 107. Oral Exam: All students must attend for an oral examination. Candidates can be examined by any member of staff of the department of Pathology. A member of staff from the Departments of Haematology and Biochemistry will also be examining. Repeat Examination: This will be held in May/June of the following year. Tutorials will be given to students on a weekly basis right up to the written examination. 52 Instruction on filling in MCQ Answer Sheets for Computer Marking of MCQs. It is important that you read these instructions and fill in the MCQ answer sheet as instructed. Failure to do this correctly may result in the computer failing to detect your answers. 1. Use only pencil to mark the answers. If a mistake is made the mark can be erased easily. The computer will not for example recognize the following:(A) (B) (C) (D) (E) 2. Write your name and student number on both the answer sheet and the question book. 3. Each student number begins with the digit 0. 4. All questions are numbered 1 – 120. 5. All answers are alphabetical (A,B. etc.) 6. Mark for correct answer = 1. Mark for no answer = 0. No negative marking. 7. Make pencil marks to indicate your answers as follows:e.g. answer is C. (A) (B) (C) (D) Do not mark answers with a tick X or circle. 8. Mark all answers on the answer sheet and also in the question book. 9. Part two of the examination consists of slides. Continue answering on the answer sheet nos. 31-40. The question book must be submitted with the answer sheet. Leave all papers at your place. Do not leave the exam center with any part of the examination. 53 PAST EXAMINATION PAPERS Ollscoil na hEireann, Gaillimh National University of Ireland, Galway Spring Examination 2000/2001 Fourth Medical, Part I Examination Pathology Answer five questions, including one from each section. Use separate answer books for each question. Time allowed: Three hours Section A Dr. Christopher Wright 1. Write an essay on the aetiology and possible complications of deep venous thrombosis of the lower limbs. 2. Give an account of the pathology of intracranial space-occupying lisioins. Section B Professor C.E. Connolly Dr. M.P.G. Little Dr. Gabriel Mortimer Dr. Helen Grimes Dr. Brendan Fitzpatrick 3. What malignant tumours can be looked for in their early phase of growth, by screening? Discuss the pathological aspects of one such tumour in depth. 4. Write an essay on pathological calcifications. 5. Give an account of aetiological factors in congenital heart disease with illustrative examples. 6. Discuss two of the following: (a) The advantages and limitations of measuring serum tumour markers giving examples. (b) The advantages and limitations of biochemical markers in the diagnosis of myocardial muscle damage giving examples. (c) The significance of hyperlipidaemia as a risk factor for cardiovascular disease, and the biochemical laboratory investigation of hyperlipidaemia. 7. Write brief notes on three of the following: (a) Membranous nephropathy (b) Minimal change disease (c) Adult polycystic disease (d) Nephrotic Syndrome 54 8. Section C Professor E. Egan Dr. Margaret Murray 9. What are the myeloproliferations diseases? Discuss on in depth? 55 Ollscoil na hEireann, Gaillimh National University of Ireland, Galway Spring Examination 2000 Fourth Medical, Part I Examination Pathology Answer five questions, including one from each section. Use separate answer books for each question. Time allowed: Three hours Section A Professor Alaister Burt 1. Discuss the different forms of Malignant Lung tumour. Discuss the possible clinical effects of complications of such tumours. 2. Write short notes on three of the following: (a) Autoimmune Thyroid Disease (b) Cervical Intraepithelial Neoplasia (c) Raised Intracranial Pressure (d) Coagulative Necrosis Section B Professor C.E. Connolly Dr. M.P.G. Little Dr. Gabriel Mortimer Dr. Helen Grimes 3. Write an essay on Malignant Lymphoma. Outline a broad classification of the different subtypes. 4. Define an aneurysm. Give a description of the types found in human with particular reference to aetiology and site. 5. What pathological features of a malignant tumour are useful in determining its prognosis? Give examples to illustrate your answer. 6. Discuss the laboratory investigation of two of the following: including a brief outline of the biochemical basis for the tests chosen: (a) Hypercalcaemia in a 50 year old female (b) Recurrent chest pain in a 60 year old male (c) Jaundice in a 25 year old female. Section C Professor E.Egan Dr. Margaret Murray 7. List the cause of Iron Deficiency Anaemia and detail the investigation of a Hypochromic Microcytic Anaemia in a 40 year old male Irish Physician. Or Discuss the classification, clinical features and pathology of Acute Myeloid Leukaemia. 56 Ollscoil na hEireann, Gaillimh National University of Ireland, Galway Summer Examination 2000 Fourth Medical, Part I Examination Pathology Time allowed: Three hours Answer five questions, including one from each section. Use separate answer books for each question. Section A Professor W. Brocker 1. Give an account of the pathological sequence of events in acute myocardial infarction. What are the main complications in patients suffering myocardial infarction? 2. Describe the difference in morphology and behaviour between benign and malignant tumours. Illustrate with examples you know. Section B Professor C.E. Connolly Dr. M.P.G. Little Dr. Gabriel Mortimer 3. Write notes on three of the following: (a) Granulation tissue (b) Hyperplasia v Hypertrophy (c) Granulomatous Inflammation (d) Metaplasia and Dysplasia 4. Discuss tumours of the testis. 5. Give an account of aortic valve, stenosis (AS) and mitral valve stenosis (MS), with particular emphasis on aetiology and complications. 6. Write an essay on peptic ulceration, include in your answer an account of the etiology and pathology and complications. Section C Professor E. Egan Dr. Margaret Murray 7. What is a Haemolytic Anaemia? Discuss the general features. List four causes. or List three congenital bleeding diseases and discuss one. 57 Ollscoil na hEireann, Gaillimh National University of Ireland, Galway Spring Examination 1999 Fourth Medical, Part I Examination Pathology Time allowed: Three hours Answer five questions, including one from each section. Use separate answer books for each question. Section A Professor A. Burt 1. Describe the pathology of Acute Myocardia Infarction and outline the complications of this condition. 2. Write an essay on Ulcerative Colitis including an account of its pathology and complications. Section B Professor C.E. Connolly Dr. M.P.G. Little Dr. Gabriel Mortimer 3. Write notes on three of the following with examples: (a) the difference between Granulation Tissue and a Granuloma. (b) the pathology of the nephritic syndrome (c) the difference between coup and contre coup injuries (d) the staging of colorectal carcinoma 4. Briefly compare and contrast carcinoma of the cervix uteri with carcinoma of the uterine corpus. 5. Discuss two of the following: (a) the limitations and advantages of measuring P.S.A. (prostate specific antigen) in the general population. (b) the significance and further investigation of a 30 year old female with a moderately elevated T.S.H. (thyroid stimulating hormone). (c) the laboratory investigation of a patient presenting with chest pain. 6. Accurately define bacteraemia septicaemia and pyaemia. Discuss their pathogenesis and pathological effects. 58 Section C Professor E. Egan Dr. Margaret Murray 7. Discuss vitamin B12 or Folic Acid deficiency listing causes, manifestations and treatment principles. or Classify the acute leukaemias and discuss the aetiology, pathogenesis and clinical features of acute leukaemia. 59 Ollscoil na hEireann, Gaillimh National University of Ireland, Galway Summer Examination 1999 Fourth Medical, Part I Examination Pathology Time allowed: Three hours Answer five questions, including one from each section. Use separate answer books for each question. Section A Professor W. Brocker 1. Give an account of the pathogenesis of glomerulonephritis and explain the difference subtypes with reference to the Nephritic and Nephrotic Syndrome. 2. Give an account of the pathogenesis symptoms, course and clinical findings of hepatitis A to D. Section B Professor C.E. Connolly Dr. M.P.G. Little Dr. Gabriel Mortimer 3. Write an essay on the pathology of Carcinoma of the Breast. Include a note on important prognostic factors. 4. Give an accurate definition on an Embolus and discuss the various types and the situations in which they arise. 5. Compare and contrast Carinoma of the Oesophagus and Carcinoma of the Stomach. 6. Write notes on three of the following: Primary vs Secondary tuberculosis of the lungs Subarachnoid vs Subdural haemorrhage In situ vs Infiltrating Carcinoma Screening techniques to detect early Cancer. Section C Professor E. Egan Dr. M. Murray 7. Discuss the causes of iron deficiency anaemia with special reference to a 40 year old Irish male. How is the diagnosis confirmed? What investigations might be appropriate? 8. List the Myeloproliferative diseases. Discuss one in detail. 60 CONTACT DETAILS Department of Pathology Staff and contact details. Name Professor C.E. Connolly Professor E. Egan Dr. M.P.G. Little Dr. H. Grimes Dr. G. Mortimer Dr. J. Callaghan Dr. B. Fitzpatrick Dr. M. Murray Dr. J. McMahon Ms. Laura Moran Ms. Rosanne Rafferty Title Head of Department Haematology Statutory Lecturer Clinical Lecturer (Biochemistry) Clinical Lecturer Clinical Lecturer Clinical Lecturer Clinical Lecturer Lecturer Senior Technician Secretary E-mail Address charles.Connolly @nuigalway.ie eganel@iol.ie -- Ext. No. 87-4488 -- 87-4607 -- 87-4592 -- 87-4415 87-4414 87-4417 -- 61 -- 87-4591 -laura.moran@nu igalway.ie -- 87-4373 87-4373 87-4077 ADDITIONAL INFORMATION 62 DEPARTMENT OF MEDICINE 63 LECTURE & PRACTICAL TIMETABLES The handbook details for Medicine are not yet complete. Please check all details of attachments, lecture timetable etc. with the Department of Medicine. We will remove this notice when we are certain that the details are fully accurate and up to date. 64 ATTACHMENT DETAILS FOURTH YEAR MEDICAL STUDENTS 2001 (1ST TERM – FINAL CLASS 2004) Students are assigned to MEDICINE & SURGERY in 1st Term A as indicated: Students are reminded that their progress will be assessed by a MULTIPLE CHOICE EXAMINATION at the end of the term. Marks obtained at this examination will constitute a proportion of their marks in the FINAL MEDICAL EXAMINATION. 1ST Term A 1st Term B 1st Term C - 17th September – 19th October 22nd October - 16th November 19th November – 14th December 1ST TERM A – 17TH September – 19th October MEDICINE Dr. B. Duffy/Merlin Park Kyne, Fiona Lynch, Maeve McHale, Sabrina Mondongo, Chawangwa O’Mahony, Matthias O’Neill, Lorraine Samat Muttaqillah, N.A. Walsh, Sinead Matingal, Julian Dr. Coughlan/Merlin Park Madigan, Nicolas McMonagle, Caroline Mohd Abdullah, Azlin Darita Murphy, Liza O’Connor, David O’Malley, Declan Roche, Kate Saidha, Shiv Sainal, Faridatul Nagandran, Yoghini Dr. S. O’Keeffe/Merlin Park Killeen, Martina Lally, Gillian Mat Rani Ghani, Mohd Yurzi Neylon, Mary NiChonchubhair, Caitlin Ni Mhaille, Grainne O’Brien, Niall O’Grady, Michael Rahman Sabri, Marina Randhawa, Rajinder 65 Dr. Gilmartin/Merlin Park Larkin, Caroline Liu, Hsien Tzo Lynch, Deirdre Makgasa, Moneimang Mulkerrins, Lorraine O’Gorman, Joanne Tully, John Wauchope, Suzanne Yarlagadda, Radesh Paipieng, Michelle COURSE DESCRIPTION COURSE OBJECTIVES 66 READING LISTS Author Title Useful WWW SITES 67 STUDENT ASSESSMENTS & PROJECTS 68 PAST EXAMINATION PAPERS 69 CONTACT DETAILS Staff member Ms. M. Bourke Dr. Robert J. Coughlan Dr. K. Daly Dr. B. Duffy Prof. P. Finnegan Dr. S. Fleming Prof. T. O'Brien Dr. J.J. Gilmartin Ms. M. Kearns Ms. N. McGready Dr. John Moran Dr. E. Mulkerrins Ms. U. O'Connor Dr. D. O'Gorman Dr. T.A. O'Gorman Dr. F. Stevens Ms. B. Walsh Title Snr. Technician Clinical Lecturer Lecturer Lecturer Associate Professor Researcher E-mail Extension mary.bourke@nuigalway.ie 87-4291 -- 757631 --med.faculty@nuigalway.ie 87-4542 757631 87-4568 -- 87-4582 Clinical Lecturer Sen. Technician Sen. Technician Clinical Lecturer Clinical Lecturer Secretary -- 757631 miriam.kearns@nuigalway.ie 87-4291 Professor 87-4287 -- 87-4257 -- 87-4682 -- 87-4206 Clinical Lecturer Lecturer -- 87-4487 -- 87-4471 Lecturer fiona.stevens@nuigalway.ie 87-4476 Researcher -- 87-4583 70 ADDITIONAL INFORMATION 71 DEPARTMENT OF SURGERY 72 LECTURE & PRACTICAL TIMETABLES The handbook details for Surgery are not yet complete. Please check all details of attachments, lecture timetable etc. with the Department of Surgery. We will remove this notice when we are certain that the details are fully accurate and up to date. Every Tuesday at 8:15 a.m. a Surgical Meeting takes place in Lecture Hall II at the Clinical Science Institute. Eight different teams rotate to do the presentations. Key cases are presented with clinical histories, pictures, etc. and discussion follows the presentations. All lectures are held on Wednesday at 5.00 p.m. in Lecture Hall 11, in the Clinical Science Institute. Initial Lecture Programme is enclosed. Any changes will be notified. Lecture No. Date of Lecture Lecturer Title of Lecture 1 26/09/01 Mr. T. FiuzaCastineira Colorectal Cancer 2 03/10/01 Mr. O. McAnena Biliary Tract and Liver 3 10/10/01 Mr. T. FiuzaCastineira Herniae 4 17/10/01 Mr. Siddiqui Inflammatory Bowel and Diverticular Disease 5 24/10/01 Mr. T. FiuzaCastineira Nutrition Fluids in Surgery 6 07/11/01 Professor Given Breast Cancer 7 14/11/01 Mr. O.McAnena Oesophageal Disorders 8 21/11/01 Mr. D. Courtney Peripheral Vascular Disease 9 28/11/01 Mr. D. Courtney The Acute Abdomen 10 05/12/01 Professor Given Benign Breast Conditions 11 09/01/02 Mr. O. McAnena Oesophagus and Diaphragm 12 16/01/02 Mr. D. Courtney Aneurysmal 73 Disease 13 23/01/02 Mr. D. Courtney Veins and Lymphatics 14 30/01/02 Mr. D. Quill Thyroid and Parathyroid 15 06/02/02 Mr. T. FiuzaCastineira Approach to the Surgical Patient and Pre-operative Care. 16 13/02/02 Mr. T. FiuzaCastineira Complications in Surgery Surgical Epidemiology/Basic Surgical Procedures 17 20/02/02 Professor Given Stomach and Duodenum 18 27/02/02 Mr. T. FiuzaCastineira Antibiotics/Surgical Infection When attached to a Surgical team, you will receive Tutorials from Members of the Team. Timetable of this Tutorials will be given to you at the time of your attachment, as they may undergo change from time to time. 74 ATTACHMENT DETAILS SURGERY Mr. M. Corcoran/UCHG Al-Kareem, Mohamed Cafferty, Ornaith Donnelly, Catherine Hegarty, Maeve Kelly, Yvonne Kieran, Elaine Bin Mohd Farid, Ahmad Rifai Ching, Lee Ee Mr. O’Sullivan/Merlin Park Allen, Rodney Burke, Aine Gaolebale, Ponatshego Mr. H. Bredin/UCHG Abdul-Jauwad, Hend Binti Ahmad, Termizi Browne, Anne Carney, Olivia Donnelly, Cormac Jennings, Lorraine Hoong, Chang Kah Kanda-Many, Nandini Mr. Martin/Casualty/UC HG Abdul Aziz, Mardiana Beatty, Sharon Benton, Aoife Bolkim, Darwina Binti Cawley, Derek Harrison, Michael Hawkins, Michael Hawkins, Finn Kavanagh, Anna Mr. McCabe/Merlin Park Christopher, Brian Cairns, Ciarin Gannon, Paul Galvin, Sarah Mr. Curtin/Merlin Park Ala, Nazeem Khursheed Burke, Tomas Gallagher, Margaret Mr. K. Kaar/Merlin Park Khanji, Mohammed Kemple, Peter Kerin Emmett 75 COURSE DESCRIPTION Welcome to the General Surgery –Vascular course. During this year you will acquire knowledge about the most common problems found in surgical patients. You should remember that the lectures are aimed to give you a synopsis of these pathologies and you should obtain further knowledge through the books mentioned on the list below. The surgical skills will be acquired through the different surgical attachments. During these attachments you will be encouraged to attend the surgical meetings, ward rounds, outpatients, and theatre sessions. You will take clinical histories from patients allocated, and you will present these cases to team members, who may ask you to demonstrate your findings. You will be expected to dress appropriately at all times in the Hospital; treat the patients with courtesy and remember that the information obtained must be treated with confidentiality. COURSE OBJECTIVES 1. To encourage students to further their knowledge and understanding of the basic medical sciences and learn to apply these on clinical situations. 2. To consolidate their surgical skills in History taking, examination and interpretation, obtaining a differential diagnosis to back the investigations that will have to be organised to confirm the diagnosis. 3. To acquire knowledge regarding the most common surgical pathologies encountered, and be able to recognise these in the clinical scenarios. 4. To learn how to approach patients and interact with team members. 76 READING LISTS Scott An aid to Clinical Surgery Grace,Hennessy,Cushieri… Clinical Surgery Burnard / Young New Aird’s Companion in Surgical Studies. Bailey & Love’s Short Practice of Surgery Hamilton Bailey’s Physical Signs All these books are available in the library Useful WWW SITES www.facs.org www.rcsi.ie www-medlib.med.utah.edu www.rad.upenn.edu www.comp.leeds.ac.uk/comir/resources/links_c.html http://sprojects.mmi.mcgill.ca/mammography/imageanalysis.htm 77 STUDENT ASSESSMENTS & PROJECTS During the fourth year, students will be submitted to two Multiple Choice Questions exam papers. The first, will take place before Christmas and the other around Easter. During the past years MCQ’s exams have had very bad results. We think this is due to the students expend very little time reading surgical texts. MCQ’s exams are aimed to test the extent of knowledge acquired. The lectures, on its own, are not sufficient. We are planning to do a clinical exam this year at the end of the Summer term. This has not being specified yet, but will be aimed to assess clinical Skills in Surgery and Medicine. 78 PAST EXAMINATION PAPERS MCQ papers are available in the Medical Library. 79 CONTACT DETAILS Department of Surgery Staff and contact details. Staff member Mr. H. Bredin Ms. G. Clarke Mr. M. Corcoran Ms. G. Comer Mr. D. Courtney Ms. C. Curran Mr. W. Curtin Mr. M. FX Gilmore Prof. F. Given Mr. P.K. Gormley Mr. F. Kinsella Mr. J. Lang Mr. A. Martin Mr. O.J. McAnena Mr. J. McCabe Mr. J. McCann Mr. M.E. O'Sullivan Mr. D. Quill Mr. P. Regan Mr. K. Tobin Title Clinical Lecturer Secretary Lecturer Clinical Lecturer Lecturer Snr. Technican Clinical Lecturer Clinical Lecturer Professor Clinical Lecturer Clinical Lecturer Clinical Lecturer Clinical Lecturer Clinical Lecturer Clinical Lecturer Clinical Lecturer Clinical Lecturer Lecturer Clinical Lecturer Lecturer E-mail -- Extension 87-4388 grace.clarke@nuigalway.ie --- 87-4202 87-4297 87-4816 -catherine.curran@nuigalway.ie 87-4300 87-4202 -- 757631 -- 757631 fred.given@nuigalway.ie -- 87-4637 87-4347 -- 87-4208 -- 87-4552 -- 87-4556 -- 87-4300 -- 757631 -- 87-4638 -- 757631 --- 87-4207 87-4714 -- 87-4269 80 ADDITIONAL INFORMATION 81