BIOGRAPHICAL SKETCH Provide the following information for the key personnel and other significant contributors in the order listed on Form Page 2. Follow this format for each person. DO NOT EXCEED FOUR PAGES. NAME POSITION TITLE Gavrilova, Natalia S. Senior Research Associate eRA COMMONS USER NAME ngavrilova EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) INSTITUTION AND LOCATION Moscow State University, Russia Moscow State University, Russia University of Chicago DEGREE (if applicable) YEAR(s) M.S. Ph.D. M.S. 1977 1982 2003 FIELD OF STUDY Chemistry Anthropology Computer Science A. Personal Statement My research and teaching interests have been focused on mortality and biological, socio-economic and environmental influences on longevity and health in humans and I am particularly interested in applying interdisciplinary approach to the study of human aging. My work at the Center on the Demography and Economics of Aging at the University of Chicago has reinforced my abilities to conduct research on biodemography of aging. Working with large databases on human longevity led me to the necessity of improving my research skills in the area of computer science. As a result, I successfully finished a Graduate Program in Computer Science at the University of Chicago and received a master degree in computer science in 2003. These additional skills reinforced my ability to study human longevity and made it possible to apply innovative techniques of web automation to the collection of data on American centenarians. This technique is being used now in the interdisciplinary research project on biodemography of exceptional longevity in the United States funded by the National Institute on Aging where I am a Co-Investigator. B. Positions and Honors Positions and Employment 1981-1982 Research Scientist, Institute of General Genetics, Academy of Sciences, Moscow 1982-1983 Research Scientist, Department of Biology, Moscow State University 1983-1987 Senior Research Scientist, Institute for Medical Information, Moscow 1987-1993 Principal Research Scientist, Institute for Medical Information, Moscow 1993-1997 Senior Research Scientist, Institute for Systems Analysis, Moscow 1997-Present Sr. Research Analyst, Center on Demography and Economics of Aging, NORC at the University of Chicago 2005-Present Senior Research Associate, Department of Obstetrics and Gynecology, University of Chicago Other Experience and Professional Memberships Editorial Board Member: Demografie, Biogerontology (2006-2012). Research Proposal Reviewer: National Institutes of Health Grant Review Commitee: ZRG HOPB 02 (2005), ZRG HOPB 90 (2009), Special Emphasis Panel/Scientific Review Group 2009/10 ZRG1 PSE-J (Challenge Grant Panel), 2012 Special Emphasis PAR Panel: Biodemography of Aging ZRG1 PSE-H (59), 2013 Social Science and Population Studies Panel B (SSPB); The Maurice Falk Institute for Economic Research in Israel. Referee (manuscript reviewer): AGE (Journal of the American Aging Association), American Journal of Human Biology, American Journal of Public Health, Annals of Epidemiology, Biogerontology, Biology Letters (Royal Society), Comparative Economic Studies, Demography, Economics & Human Biology, Europe-Asia Studies, European Journal of Population, Experimental Gerontology, Gender Medicine, Genus, Gerontology, Human Genetics, International Journal of Epidemiology, Journal of the American Geriatrics Society, Journal of AntiAging Medicine, Journal of Gerontology, Journal of Theoretical Biology, Mathematical Population Studies, Mechanisms of Ageing and Development, Population, Population and Development Review, Population Research and Policy Review, Statistics in Medicine, Social Biology, Social Forces, TheScientificWorldJournal, Theoretical Population Biology Membership: Fellow of the Gerontological Society of America, Population Association of America. Consultant for the NIA: NIH Professional Service Contract #263 SDN74858. Honors Moscow Society of Naturalists. Award for the best scientific research in natural science in 1986-1988 International Science Foundation Emergency Award for Russian Scientists of the Top Category (1993) U.S. Civilian Research and Development Foundation Proposal Development Program Award (1996) Featured in Wall Street Journal (March 2nd, 2012), The NIH Record (October 26, 2012), Science (6 June 1997, p.1503), The Scientist (May 13, 2002, p.20), Sunday Times London (June 15, 1997), The Guardian, UK (September 01, 2004), IEEE Spectrum (September 2004 issue, cover story). Cited by Encyclopedia Britannica as the author of recommended book "The Biology of Life Span." Invited author for Macmillan Encyclopedia of Aging (3 articles), Journal of Theoretical Biology special issue (2001, vol. 213), Springer-Verlag monograph "Sex and Longevity" (2000), Handbook of the Biology of Aging (2005), International Handbook of the Demography of Aging (2009). C. Selected Publications (in chronological order) 1. Gavrilov L. A., and N. S. Gavrilova. 1991. The Biology of Life Span: A Quantitative Approach, New York: Harwood Academic Publisher. 385p. 2. Gavrilova, N. S., and L. A. Gavrilov. 1999. Data Resources for Biodemographic Studies on Familial Clustering of Human Longevity. Demographic Research, 1 (4): 1-48. 3. Gavrilova NS, Gavrilov LA, Semyonova VG, Evdokushkina GN. 2004. Does Exceptional Human Longevity Come With High Cost of Infertility? Testing the Evolutionary Theories of Aging. Annals of the New York Academy of Sciences, 1019: 513-517. PMID: 15247077 4. Gavrilova N.S., Gavrilov L.A. 2007. Search for predictors of exceptional human longevity: using computerized genealogies and internet resources for human longevity studies. North American Actuarial Journal, 11(1): 49-67. PMID: 22308064 5. Gavrilova N., Lindau S.T. 2009. Salivary sex hormone measurement in a national, population-based study of older adults. The Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 64, Suppl.1, i94-105. doi:10.1093/geronb/gbn028. PMID: 19204073. PMCID: PMC2763516 6. Lindau, S.T. and Gavrilova, N. 2010. Sex, health, and years of sexually active life gained due to good health: evidence from two US population based cross sectional surveys of ageing. British Medical Journal 340: c810. doi: 10.1136/bmj.c810. PMID: 20215365. PMCID: PMC2835854 7. Gavrilova N.S., Gavrilov L.A., Search for mechanisms of exceptional longevity. Rejuvenation Research, 2010, 13(2-3): 262-264. PMID: 20370503. PMCID: PMC2946054 8. Guillot M, Gavrilova N, Pudrovska T. Understanding the "Russian mortality paradox" in Central Asia: Evidence from Kyrgyzstan. Demography, 2011, 48(3): 1081-1104. PMID: 21618068. PMCID: PMC3315848 9. Gavrilova N.S., Gavrilov L.A. Comments on dietary restriction, Okinawa diet and longevity. Gerontology, 2012, 58(3): 221-223. DOI: 10.1159/000329894. PMID: 21893946. PMCID: PMC3362219 10. Gavrilov L.A., Gavrilova N.S. Season of birth and exceptional longevity: Comparative study of American centenarians, Their Siblings, and Spouses. Journal of Aging Research, 2011, Article ID 104616, 11 pages, doi:10.4061/2011/104616. PMID: 22187646. PMCID: PMC3236478 11. Gavrilova N.S., Gavrilov L.A., Severin, F.F. and Skulachev, V.P. Testing predictions of the programmed and stochastic theories of aging: Comparison of variation in age at death, menopause, and sexual maturation. Biochemistry (Moscow), 2012, 77(7), 754-760. PMID: 22817539. PMCID: PMC3428266 12. Gavrilov L.A., Gavrilova N.S. Biodemography of exceptional longevity: Early-life and mid-life predictors of human longevity. Biodemography and Social Biology, 2012, 58(1):14-39, DOI: 10.1080/19485565.2012.666121. PMID: 22582891. PMCID: PMC3354762 13. Guillot M, Gavrilova N, Torgasheva L, Denisenko M. Divergent Paths for Adult Mortality in Russia and Central Asia: Evidence from Kyrgyzstan. PLoS ONE, 2013, 8(10): e75314. doi:10.1371/journal.pone.0075314. PMID: 24116034. PMCID: PMC3792976 14. Gavrilov LA, Gavrilova NS. Determinants of exceptional human longevity: new ideas and findings. Vienna Yearbook of Population Research 2013;11:295-323. PMCID: PMC4165392. 15. Gavrilova NS, Gavrilov LA. Biodemography of old-age mortality in humans and rodents. J Gerontol A Biol Sci Med Sci 2014:Feb 17. [Epub ahead of print], doi: 0.1093/gerona/glu009. PMID: 24534516. PMC Journal - In Process. D. Research Support Ongoing Research R01 AG028620 (Gavrilov) 1/1/09 to 31/12/13 (unfunded continuation to 12/31/2014) NIA Biodemography of Exceptional Longevity in the United States This project proposes to investigate why some people manage to survive to extreme old age (100+ years) and what are the biological and social correlates of exceptional longevity. The project will take advantage of the ongoing revolution in information technology for human longevity studies to examine the determinants of exceptional survival both on individual and population levels, using a rich variety of the U.S. data sources available through the Internet, including Social Security Administration datasets, Census data, family reconstitutions and validated genealogies, and military draft records. Role: Co-Investigator Completed Research (The Last Three Years) P30 AG012857 (Waite) 8/15/97 to 6/30/14 NIA “Center on Demography and Economics of Aging” The Center on Aging consists of the four cores: (1) an Administrative and Research Support Core, (2) a Program Development Core, (3) an External Innovative Network Core focusing on Biological Measures in Aging and (4) an External Research Resources Support and Dissemination Core. These four cores together continue to facilitate and support a large and extremely active program of research and training at Chicago. The focus of the Center include: (1) social relationships, living arrangements and family; (2) the social context of aging; (3) health care research; and (4) biobehavioral pathways. Role: Sr. Project Professional, Chicago Core on Biomarkers in Population-Based Aging Research (CCBAR). R01HD045531 (Guillot) 4/15/06 – 2/28/11 NICHD “Mortality in Central Asia” The goal of this project is to improve our knowledge of mortality in former Soviet Central Asia. Role: Co-Investigator