Database: MEDLINE <1966 to May Week 4 2002> Search Strategy: (Medial collateral ligament injuries) ------------------------------------------------------------------------------1 exp Knee Injuries/ (8213) 2 exp COLLATERAL LIGAMENTS/in [Injuries] (426) 3 1 and 2 (120) 4 limit 3 to (human and english language) (97) 5 limit 4 to yr=1996-2002 (68) 6 medial.tw. and 5 (32) 7 from 6 keep 1-32 (32) 8 from 7 keep 1-32 (32) *************************** <1> Unique Identifier 9059420 Medline Identifier 97212564 Authors Lundberg M. Thuomas KA. Messner K. Institution Department of Orthopaedics and Sports Medicine, University Hospital, Linkoping, Sweden. Title Evaluation of knee-joint cartilage and menisci ten years after isolated and combined ruptures of the medial collateral ligament. Investigation by weight-bearing radiography, MR imaging and analysis of proteoglycan fragments in the joint fluid. Source Acta Radiologica. 38(1):151-7, 1997 Jan. Abstract PURPOSE: To compare radiography, MR imaging, and chemical analysis in posttraumatic knees. MATERIAL AND METHODS: Ten matched pairs with either isolated partial rupture of the medial collateral ligament or combined medial collateral ligament/anterior cruciate ligament rupture were compared with matched controls 10 years after trauma. Weight-bearing radiographs and MR examinations were compared with proteoglycan fragment concentrations in the joint fluid. RESULTS: The chemical analyses were similar in both trauma groups. The radiographs showed mild signs of arthrosis in half the patients with combined injury. MR images showed almost all injured knees to have degenerative changes of various degrees in the cartilage and menisci. More frequent and more advanced changes were found after combined injury than after isolated injury (p < 0.01). There were no changes in the controls. CONCLUSION: MR imaging is the best method for detecting and differentiating early posttraumatic knee arthrosis. <2> Unique Identifier 9762977 Medline Identifier 98433941 Authors De Maeseneer M. Lenchik L. Starok M. Pedowitz R. Trudell D. Resnick D. Institution Department of Radiology, Veterans Administration Medical Center, San Diego, CA 92161, USA. Title Normal and abnormal medial meniscocapsular structures: MR imaging and sonography in cadavers. Source AJR. American Journal of Roentgenology. 171(4):969-76, 1998 Oct. Abstract OBJECTIVE: The purpose of this study was to develop imaging criteria for the diagnosis of meniscocapsular separation by correlating findings on MR imaging, MR arthrography, and sonography of normal and abnormal medial meniscocapsular structures with corresponding anatomic sections in cadavers. MATERIALS AND METHODS: Eight cadaveric knee specimens were examined with MR imaging, MR arthrography, and sonography before arthroscopy. In six specimens the following lesions were arthroscopically created: meniscocapsular separation (n = 3), medial collateral ligament (MCL) tear (n = 3), tear of the meniscofemoral extension of the deep MCL (n = 2), and coronary ligament tear (n = 2). After arthroscopy, all imaging studies were repeated. The specimens were sectioned for correlation with imaging studies. RESULTS: MR findings that correlated with meniscocapsular separation were interposition of fluid between the meniscus and the MCL, irregular meniscal outline, and increased distance between the meniscus and the MCL. On MR arthrography meniscocapsular separation correlated with interposition of contrast medium between the meniscus and the MCL. Tears of the meniscofemoral extension of the deep MCL were best shown on MR arthrography. Sonography showed deep and superficial MCL lesions but did not show meniscocapsular separations. CONCLUSION: In arthroscopically created meniscocapsular separation, the lesion is suggested on MR images when fluid is interposed between the meniscus and the MCL, when the meniscal outline is irregular, or when the distance between the meniscus and the MCL is increased. On MR arthrograms, a meniscocapsular separation is suggested when contrast medium is interposed between the meniscus and the MCL. Sonography does not allow accurate diagnosis of meniscocapsular separation. <3> Unique Identifier 9574586 Medline Identifier 98233773 Authors Rubin DA. Kettering JM. Towers JD. Britton CA. Institution Department of Radiology, University of Pittsburgh Medical Center, PA 15213, USA. Title MR imaging of knees having isolated and combined ligament injuries. [see comments.]. Comments Comment in: AJR Am J Roentgenol. 1999 Jan;172(1):239-40 ; 9888775 Source AJR. American Journal of Roentgenology. 170(5):1207-13, 1998 May. Abstract OBJECTIVE: Although clinical evaluation and MR imaging both accurately reveal injuries in knees with isolated ligament tears, physical examination becomes progressively less reliable when multiple lesions exist. We investigated the accuracy of MR imaging of knees having varying degrees and numbers of ligament injuries. SUBJECTS AND METHODS: We prospectively interpreted the MR images of 340 consecutive injured knees and compared these interpretations with the results of subsequent arthroscopy or open surgery, which served as the gold standard. Our interpretations of MR images focused on five soft-tissue supporting structures (the two cruciate ligaments, the two collateral ligaments, and the patellar tendon) and the two menisci. Patients were divided into three groups: no ligament injuries, single ligament injuries, and multiple ligament injuries. RESULTS: Using MR imaging, we found overall sensitivity and specificity for diagnosing ligament tears to be 94% and 99%, respectively, when no or one ligament was torn and 88% and 84%, respectively, when two or more supporting structures were torn. The difference in specificity was statistically significant (p < .0001). Sensitivity for diagnosing meniscal tears decreased as the number of injured structures increased, but the relationship achieved statistical significance (p = .001) only for the medial meniscus. For all categories of injury, MR imaging was more accurate than clinical evaluation, statistics for which were taken from the orthopedic literature. CONCLUSION: In knees with multiple ligament injuries, the diagnostic specificity of MR imaging for ligament tears decreases, as does the sensitivity for medial meniscal tears. <4> Unique Identifier 10626911 Medline Identifier 20090337 Authors Shelbourne KD. Jennings RW. Vahey TN. Institution Methodist Sports Medicine Center, Indianapolis, Indiana, USA. Title Magnetic resonance imaging of posterior cruciate ligament injuries: assessment of healing. Source American Journal of Knee Surgery. 12(4):209-13, 1999 Fall. Abstract This study evaluated posterior cruciate ligament (PCL) healing using magnetic resonance imaging (MRI). Forty knees with acute PCL injuries underwent acute and follow-up (>6 months) MRI examinations. Twenty-three knees had isolated injuries, and 17 knees had associated ligament damage. The initial MRI scans showed 22 high-grade injuries with complete disruption, 14 with midgrade injuries with extensive edema on T2 images with some bridging fibers present, and 4 patients had low-grade injuries. At a mean time of 3.21.3 years after the initial MRI, the follow-up MRIs revealed the PCL healed with continuity in all of the low-grade and midgrade injuries, and in 19 of 22 high-grade injuries. Of the 19 high-grade PCL tears that healed, 4 healed with normal contour and 15 were continuous with altered morphology at follow-up. Of 11 high-grade PCLinjured knees with associated ligament damage, only 1 PCL failed to regain continuity. The 3 PCLs that did not regain continuity were in 2 patients with isolated injuries and 1 patient with associated anterior cruciate and medial collateral ligament injuries. These results demonstrate that most nonoperatively treated PCL injuries, even in association with other knee ligament damage, can heal with continuity. <5> Unique Identifier 9006689 Medline Identifier 97159349 Authors Hull ML. Institution Department of Mechanical and Aeronautical Engineering, University of California, Davis 95616-5294, USA. Title Analysis of skiing accidents involving combined injuries to the medial collateral and anterior cruciate ligaments. Source American Journal of Sports Medicine. 25(1):35-40, 1997 Jan-Feb. Abstract Two types of ligament injuries common in skiing are the isolated ruptures of the anterior cruciate and ruptures of the medial collateral, either with or without rupture of the anterior cruciate. Based on research related to ligament injury mechanics and two-mode release binding function, the purpose of this paper was to critically assess the ability of two-mode release bindings to prevent combined medial collateral and anterior cruciate ligament injuries. Making this assessment entailed several steps. First, I determined the loads typically transmitted by the knee during falls in which combined injuries occurred. Because more than one load was transmitted, the next step was to discern which of the loads was more damaging. Finally, heel-toe type bindings were evaluated for their potential to release in response to damaging loads. I concluded that combined medial collateral and anterior cruciate ligament injuries typically occur in forward, twisting-type falls in which the primary loads are external axial and valgus moments. An external axial moment is more damaging than a valgus moment, both to the medial collateral ligament when the joint is intact and to the anterior cruciate ligament when the medial collateral ligament is damaged. Because heel-toe type bindings offer release sensitivity to this moment, the release level of the toepiece in twist is an important factor in the prevention of these injuries. <6> Unique Identifier 9167817 Medline Identifier 97310918 Authors Levy AS. Wetzler MJ. Lewars M. Laughlin W. Institution American Orthopaedic Rugby Football Association, Philadelphia, Pennsylvania, USA. Title Knee injuries in women collegiate rugby players. Source American Journal of Sports Medicine. 25(3):360-2, 1997 May-Jun. Abstract We evaluated the prevalence and patterns of knee injuries in 810 women collegiate rugby players. Injuries that resulted in players missing at least one game were recorded and a questionnaire was used to delineate players' rugby and knee injury history. There were 76 total knee injuries in 58,296 exposures. This resulted in a 1.3 knee injury rate per 1000 exposures. Twenty-one anterior cruciate ligament tears were reported for a 0.36 incidence per 1000 exposures. Other injuries included meniscal tears (25), medical collateral ligament sprains (23), patellar dislocations (5), and posterior cruciate ligament tears (2). Sixty-one percent of the medial collateral ligament sprains occurred in rugby forwards and 67% of anterior cruciate ligament tears occurred in rugby backs. All other injuries occurred with equal frequency in backs and forwards. This study demonstrates that knee injury rates in women's collegiate rugby are similar to those reported for other women's collegiate sports. The overall rate of anterior cruciate ligament injury in women's rugby, however, is slightly higher than that reported for women soccer and basketball players. <7> Unique Identifier 9474396 Medline Identifier 98134737 Authors Miller MD. Osborne JR. Gordon WT. Hinkin DT. Brinker MR. Institution United States Air Force Academy Hospital, Colorado, USA. Title The natural history of bone bruises. A prospective study of magnetic resonance imaging-detected trabecular microfractures in patients with isolated medial collateral ligament injuries. Source American Journal of Sports Medicine. 26(1):15-9, 1998 Jan-Feb. Abstract We conducted a prospective study to evaluate bone bruises, or trabecular microfractures, associated with isolated medial collateral ligament injuries. Magnetic resonance imaging was performed on 65 patients with isolated medial collateral ligament injuries determined by physical examination and imaging studies. Of these 65 patients, 29 (45%) had associated trabecular microfractures. Follow-up images were completed at various intervals on 24 of these 29 patients (83%). Complete resolution of these lesions was observed in all cases. This process appears to occur as a result of gradual diffusion over a period of 2 to 4 months. Bone bruises associated with medial collateral ligament injuries are approximately one-half as common as bone bruises associated with anterior cruciate ligament injuries. However, medial collateral ligamentassociated trabecular microfractures may be a better natural history model because these injuries are treated nonoperatively. <8> Unique Identifier 8775113 Medline Identifier 96371278 Authors Lundberg M. Messner K. Institution Department of Orthopaedics-Sports Medicine, University Hospital, Linkoping, Sweden. Title Long-term prognosis of isolated partial medial collateral ligament ruptures. A ten-year clinical and radiographic evaluation of a prospectively observed group of patients. Source American Journal of Sports Medicine. 24(2):160-3, 1996 Mar-Apr. Abstract We prospectively observed 38 patients with nonoperatively treated isolated partial ruptures of the knee medial collateral ligament at 3 months, 4 years, and 10 years after the initial trauma using clinical and radiographic examinations. The initial diagnoses were based on clinical and arthroscopic examinations. Three months after injury, 28 patients (74%) had regained nearly normal knee function and muscle strength, and 75% of these patients could perform at their preinjury activity level (competitive team sports). Five patients (13%) had increased valgus laxity (grade 1) in the injured knee. After 4 years, the patients had a median Lysholm score of 100 (range, 64 to 100). Thirty-three patients (87%) had normal knee function during strenuous activities. Repeat injuries to the medial collateral ligament occurred in two patients (5%), and another two patients sustained cruciate ligament injuries during the follow-up period. After 10 years, the Lysholm score (median, 95; range, 73 to 100) was lower compared with the 4-year score (P < 0.03), but the patients still performed on a similarly high activity level. Five patients (13%) had distinct signs of beginning osteoarthritis (Fairbank's signs) on radiographs, but none had joint space reduction. <9> Unique Identifier 10496578 Medline Identifier 99424897 Authors Nordt WE 3rd. Lotfi P. Institution Plotkin E. Williamson B. West End Orthopaedic Clinic, Richmond, Virginia 23229, USA. Title The in vivo assessment of tibial motion in the transverse plane in anterior cruciate ligament-reconstructed knees. Source American Journal of Sports Medicine. 27(5):611-6, 1999 Sep-Oct. Abstract Twenty-one knees with acutely injured anterior cruciate ligaments were reconstructed with patellar tendon autografts. Eight of the knees had concomitant medial ligament injuries that were not addressed surgically. Follow-up evaluation (average, 25 months) included computed tomography measurements to analyze transverse-plane laxity in both translation and rotation. These measurements were performed with the patient's leg in a load cell device that stabilizes the distal femur and applies known anterior translational force to the proximal tibia at approximately 20 degrees of flexion. A torque apparatus was used to apply internal and external rotational torque to the leg. Images of the tibial plateau in neutral, internal, and external rotation were performed, with and without an anterior translational force. Both knees of each patient were tested and categorized as group I (anterior cruciate ligament-reconstructed) or group II (uninjured). Translation as measured by computed tomography averaged 1 mm side-to-side difference. Internal rotation averaged 8.7 degrees in group I knees and 10.8 degrees in group II knees. External rotation averaged 9.1 degrees in group I knees and 7.4 degrees in group II knees. The eight knees with concomitant medial ligament injuries were analyzed separately; external rotation without anterior load in group I was 9.5 degrees, compared with 5 degrees in group II. This difference was significant (P < 0.01). <10> Unique Identifier 9143665 Medline Identifier 97288714 Authors McDougall JJ. Bray RC. Sharkey KA. Institution Department of Surgery, University of Calgary, Alberta, Canada. Title Morphological and immunohistochemical examination of nerves in normal and injured collateral ligaments of rat, rabbit, and human knee joints. Source Anatomical Record. 248(1):29-39, 1997 May. Abstract BACKGROUND: Knee joints possess an abundant nerve supply that relays sensory and motor information on such aspects as proprioception, nociception, and vasoregulation. Although synovial innervation has been well documented, little is known of the nerves that supply the collateral ligaments. METHODS: The morphology of rabbit and human collateral ligament nerves was examined by silver impregnation. Immunohistochemistry was performed on rabbit and rat collateral ligaments to determine the presence of peptidergic nerves in these tissues. A 6-week gap injury was performed on three rabbit medial collateral ligaments, and the localisation of peptidergic nerves in these tissues was determined. RESULTS: Irrespective of species or type of ligament examined, the greatest density of nerve fibres was found in the epiligament. Nerve fibres commonly accompanied blood vessels along the long axis of the ligament and then entered the substance of the tissue before ramifying in the deeper layers. Substance P and calcitonin gene-related peptideimmunoreactive nerve fibres were found in the collateral ligaments of the rat and rabbit. Injured ligaments showed a higher than normal level of immunoreactivity in and around the healing zone; however, the nerve fibres appeared tangled and truncated. CONCLUSIONS: Like other structures in knee joints, collateral ligaments possess a complex nerve supply. The presence of peptidergic nerves suggests that ligaments may be susceptible to neurogenic inflammation and may be centres of articular nociception. <11> Unique Identifier 10447618 Medline Identifier 99376645 Authors Petersen W. Laprell H. Institution Lubinusklinik, Hospital for Surgery and Orthopedics, Steenbeker Weg 25, D-24106 Kiel, Germany. Title Combined injuries of the medial collateral ligament and the anterior cruciate ligament.Early ACL reconstruction versus late ACL reconstruction. Source Archives of Orthopaedic & Trauma Surgery. 119(5-6):258-62, 1999. Abstract Aim of this retrospective study is to evaluate the effect of acute and late anterior cruciate ligament (ACL) reconstruction in patients with a combined injury of the ACL and the medial collateral ligament (MCL). All MCL injuries were treated non-operatively. In 27 patients (group I) we performed early ACL reconstruction (within the first 3 weeks after injury). The postoperative rehabilitation protocol included brace treatment for all patients over a period of 6 weeks. In 37 patients we performed late ACL reconstruction (after a minimum of 10 weeks). In this group initial non-operative MCL treatment (6 weeks brace treatment) was followed by a period of accelerated rehabilitation. Patients with late ACL reconstruction had a lower rate of loss of motion after finishing the postoperative rehabilitation programme and a lower rate of rearthroscopies for a loss of extension (group I: 4 patients, group II: 1 patient). The difference in the mean quadriceps muscle strength (group I: 83.3%, group II: 86.3%) was not statistically significant. After a mean interval of 22 months, we saw no difference in the frequency of anterior or medial instabilities or in the loss of motion. The Lysholm score was significantly better in the group with late ACL reconstruction (group I: 85.3, group II: 89.9). The position on the Tegner activity scale decreased in both groups, to 5.5 in group I (preoperatively: 6.0) and to 5.6 in group II (preoperatively: 5.9). With regard to the lower rate of motion complications in the early postoperative period, the lower rate of re-arthroscopies, and the significantly better results in the Lysholm score, we prefer late ACL reconstruction in the treatment of combined injuries of the ACL and the MCL. <12> Unique Identifier 9685095 Medline Identifier 98348237 Authors Zuhosky JP. Dugan SA. Young JL. Bode RK. Kelly JP. Institution Department of Physical Medicine and Rehabilitation, Northwestern University Medical School, Chicago, IL, USA. Title A retrospective review of the incidence and rehabilitation outcome of concomitant traumatic brain injury and ligamentous knee injury. Source Archives of Physical Medicine & Rehabilitation. 79(7):805-10, 1998 Jul. Abstract OBJECTIVES: To estimate the incidence of ligamentous knee injuries in patients with traumatic brain injury (TBI) involved in pedestrian versus motor vehicle collisions (PVMVC), to identify associated risk factors, and to compare rehabilitation outcomes and costs in TBI patients with and without ligamentous knee injury. DESIGN: Retrospective, case control. SETTING: An academic rehabilitation hospital with a large metropolitan referral base. PATIENTS: Twenty-three consecutive adolescent and adult subjects admitted for acute inpatient rehabilitation after a PVMVC from January 1, 1994, to January 1, 1996. RESULTS: Five subjects (22%) were found to have a ligamentous knee injury, one with bilateral injuries. Two of these six injuries were diagnosed only after presentation to the rehabilitation setting. The most common injury was an anterior cruciate ligament (ACL) disruption in 5 of 6 knees. A coupled ACL and medial collateral ligament injury was identified in 4 of 6 injured knees. The risk of ligamentous knee injury was most closely associated with the presence of a tibial plateau fracture (n=3) (chi2=12.420, p < .001). There was no statistical difference between groups with and without ligamentous knee injuries with respect to age, gender, inpatient acute or rehabilitation length of stay, admission, discharge, or change in motor Functional Independence Measure (FIM) interval measures, or rehabilitation costs. Four of the 5 patients with ligamentous knee injuries were successfully managed nonoperatively. A case illustrating longitudinal management is presented. CONCLUSIONS: TBI and ligamentous knee injuries, in particular ACL injuries, are common comorbidities after PVMVC. Physicians must maintain a high index of suspicion for ligamentous knee injuries in this population, particularly when a tibial plateau fracture is present. TBI patients with and without ligamentous knee injuries can have comparable functional outcomes when the ligament injuries are identified and appropriately managed, without incurring undue cost or length of inpatient rehabilitation. <13> Unique Identifier 11337708 Medline Identifier 21234782 Authors Ambrose HC. Simonian PT. Sims WF. Institution Department of Orthopaedic Surgery, The University of Washington, Seattle, Washington 98195, U.S.A. Title Arthroscopic localization of medial collateral ligament injury: Report of 2 cases in adults. Source Arthroscopy. 17(5):E21, 2001 May. Abstract Injury to the medial collateral ligament has previously been assessed primarily using the clinical examination and magnetic resonance imaging. In this article, we describe an adjunct to these diagnostic tools: an arthroscopic observation to assess the specific location of the medial collateral ligament injury. <14> Unique Identifier 11951187 Medline Identifier 21947530 Authors Borden PS. Kantaras AT. Caborn DN. Institution Division of Sports Medicine, The University of Louisville, Louisville, Kentucky 40202, USA. Title Medial collateral ligament reconstruction with allograft using a double-bundle technique. Source Arthroscopy. 18(4):E19, 2002 Apr. Abstract Medial collateral ligament (MCL) reconstruction has been a topic of controversy in regard to the need for surgical reconstruction as well as the type of surgical reconstruction to be performed. Combined anterior cruciate ligament (ACL) and MCL reconstruction has been found to be associated with a higher incidence of postoperative arthrofibrosis than isolated ACL reconstruction; performing these reconstructions in a staged format has been proposed to avoid this devastating complication. We present a technique for MCL reconstruction that physiometrically reestablishes both anterior and posterior stabilizing components of the MCL and is performed with a limited soft-tissue dissection. This technique can easily be combined with an ACL allograft or hamstring reconstruction without need for staged or significantly delayed procedure. The technical details of this technique allow for stable fixation of an allograft reconstruction to allow for immediate postoperative knee range of motion with low patient morbidity because of the limited surgical approach. <15> Unique Identifier 9043600 Medline Identifier 97196510 Authors Maffulli N. Chan KM. Bundoc RC. Cheng JC. Institution Department of Orthopaedics and Traumatology, Chinese University of Hong Kong, Faculty of Medicine, Prince of Wales Hospital, Shatin, New Territories, Hong Kong. Title Knee arthroscopy in Chinese children and adolescents: an eight-year prospective study. Source Arthroscopy. 13(1):18-23, 1997 Feb. Abstract In the period January 1985 to December 1992, 69 Chinese boys and 20 Chinese girls (average 14.6 years, age range 6 to 16 years) with a total of 92 involved knees underwent examination under anaesthesia and knee arthroscopy. Two thirds of the patients were engaged in sports activities. A haemarthrosis was present in 51 patients. In one patient, Staphylococcus aureus was shown, and in two children a serous-purulent aspirate grew Mycobacterium tuberculosis. The lateral meniscus was torn in four knees and the medial meniscus in six. An intact discoid lateral meniscus was found in five girls. Three partial anterior cruciate ligament (ACL) tears, three complete ACL tears and two posterior cruciate ligament tears were diagnosed. One child had an osteochondral defect of the lateral femoral condyle accompanying an ACL and a lateral meniscal tear. Nonspecific synovitis of unknown etiology was diagnosed in six patients who had presented subacutely with at least a 2-month history of a symptomatic monoarticular knee effusion with low grade local inflammation and no history of major trauma. The synovitis gradually resolved over a 6- to 10-month period after arthroscopy. Knee arthroscopy in children and adolescent patients is safe, gives a high diagnostic accuracy, and allows treatment of a variety of intraarticular conditions. This study also demonstrates that the range of intraarticular knee problems found in Chinese children and adolescents differs from that described in their Western counterparts. <16> Unique Identifier 9343655 Medline Identifier 98003550 Authors MacDonald PB. Institution Section of Orthopaedics, University of Manitoba, St Boniface General Hospital, Winnipeg, Canada. Title Combined tear of the posterior cruciate and medial collateral ligaments resulting in a locked knee. Source Arthroscopy. 13(5):639-40, 1997 Oct. Abstract A case is presented of a combined tear of the posterior cruciate and medial collateral ligaments with medial collateral ligament fibers herniated through the medial capsule and occupying the medial compartment, which resulting in a locked knee. The author is not aware of any reports in the literature of this and presents this to raise awareness of another cause of knee locking. <17> Unique Identifier 10695848 Medline Identifier 20158395 Authors Munshi M. Davidson M. MacDonald PB. Froese W. Sutherland K. Institution Department of Radiology, St. Boniface Hospital, University of Manitoba, Winnipeg, Canada. Title The efficacy of magnetic resonance imaging in acute knee injuries. Source Clinical Journal of Sport Medicine. 10(1):34-9, 2000 Jan. Abstract OBJECTIVE: To evaluate the clinical efficacy of magnetic resonance imaging (MRI) of the knee in acute injuries with indeterminate clinical findings, using arthroscopy as a gold standard. DESIGN: A prospective double-blind study was performed. All patients underwent MRI on a 1.5 T magnet using dual spin echo pulse sequences. This was followed by arthroscopy. SETTING: Tertiary care referral center. PATIENTS: Twentythree patients with an average age of 26 years satisfied the study criteria. Patients had to have been seen by one of two orthopaedic surgeons within 6 weeks of sudden trauma to the knee complicated by a hemarthrosis, clinical assessment of which was equivocal. RESULTS: The respective sensitivity and specificity for MRI of the knee were 90% (18/20) and 67% (2/3) for detecting any anterior cruciate ligament injury, 50% (1/2) and 86% (18/21) for detecting medial meniscal tears, and 88% (7/8) and 73% (11/15) for detecting lateral meniscal tears. MRI also identified injuries that could not be assessed on arthroscopy, including 14 bone bruises, five posterior cruciate ligament tears, nine medial collateral ligament tears, and one lateral collateral ligament tear. The detection of composite injury requiring surgical intervention yielded a sensitivity of 100% (16/16) and a specificity of 71% (5/7). Prospective use of MRI evaluation of the knee could have prevented 22% (5/23) of diagnostic arthroscopic procedures. CONCLUSION: Equivocal clinical findings in patients with acute knee injury should lead to use of MRI in an appropriate clinical setting. To our knowledge a prospective study of the efficacy of MRI of the knee in this patient population has not been reported. In the presence of such inclusion criteria, the results of our study support the use of early MRI to guide further surgical management. <18> Unique Identifier 9007366 Medline Identifier 97159850 Authors Colletti P. Greenberg H. Terk MR. Institution LAC-USC Imaging Science Center 90033, USA. Title MR findings in patients with acute tibial plateau fractures. Source Computerized Medical Imaging & Graphics. 20(5):389-94, 1996 Sep-Oct. Abstract OBJECTIVE: The purpose of this study was to demonstrate the MRI findings associated with acute tibial plateau fractures. MATERIALS AND METHODS: MR scans of 29 patients with acute tibial plateau fractures were analyzed retrospectively. The images were evaluated for the presence of injuries involving the menisci, cruciate and collateral ligaments. The presence of a lipohemarthrosis or a simple joint effusion was also noted. The tibial plateau fractures were classified according to the scheme devised by Schatzker. RESULTS: Evidence of internal derangement of the knee was found in 28 (97%) patients. Tibial collateral ligament (55%) injuries and lateral meniscus (45%) tears were noted most frequently. Medial meniscus tears were seen in 21% and fibular collateral ligament injuries were diagnosed in 34%. Forty-one percent had anterior cruciate ligament injuries while the posterior cruciate ligament was injured in 28%. Twelve (41%) patients demonstrated the characteristic MRI features of a lipohemarthrosis. Simple joint effusions were found in the remaining 17 (59%) patients. CONCLUSION: MR imaging in patients with acute tibial plateau fractures commonly demonstrates associated ligamentous and meniscal injuries. By imaging in multiple planes, MRI can aid in the accurate characterization of tibial plateau fracture patterns and severity. <19> Unique Identifier 9639983 Medline Identifier 98304165 Authors Scoggin JF 3rd. Institution Department of Orthopaedic, Surgery and Sports Medicine, Straub Clinic & Hospital, Honolulu, Hawaii 96813, USA. Title Common sports injuries seen by the primary care physician. Part II: Lower extremity. Source Hawaii Medical Journal. 57(5):502-5, 1998 May. Abstract Sports medicine is the science of caring for the medical and surgical needs of athletes and their injuries. Injuries of the upper extremity were dealt with in Part I in a previous article. Part II deals with injuries of the lower extremity. Trochanteric bursitis and hamstring strains are treated with rest, rehabilitation, and correction of training errors. Patellofemoral pain syndromes require accurate diagnosis and usually a rehabilitative program. Injuries to the medial collateral ligament are very common, but can be associated with tears of the meniscus and cruciate ligaments. The latter two often require surgical intervention. Ankle sprains are graded by severity. The most severe can result in chronic pain or instability, but most respond well to functional bracing and progressive return to activity. <20> Unique Identifier 8727746 Medline Identifier 96284376 Authors Shelbourne KD. Patel DV. Institution Methodist Sports Medicine Center, Indianapolis, Indiana, USA. Title Management of combined injuries of the anterior cruciate and medial collateral ligaments. Source Instructional Course Lectures. 45:275-80, 1996. <21> Unique Identifier 8739577 Medline Identifier 96320798 Authors Lundberg M. Odensten M. Thuomas KA. Messner K. Institution Department of Orthopedics and Sports Medicine, University Hospital, Linkoping, Sweden. Title The diagnostic validity of magnetic resonance imaging in acute knee injuries with hemarthrosis. A single-blinded evaluation in 69 patients using high-field MRI before arthroscopy. Source International Journal of Sports Medicine. 17(3):218-22, 1996 Apr. Abstract Sixty-nine patients with traumatic knee hemarthrosis were evaluated an average of 3 days after trauma by high field (1.5T) magnetic resonance imaging (MRI) using sagittal T1, T2-weighted and coronal 3D-gradient echo images. All knees were arthroscopically examined shortly afterwards. The diagnostic validity of MRI for intraarticular pathology was determined using arthroscopy as golden standard. All patients had pathological findings on arthroscopy. The injuries were sports-related in 77% of the cases. MRI was highly sensitive (86%) and specific (92%) for diagnosis of anterior cruciate ligament tears. Diagnosis of medial meniscal tears showed a 74% sensitivity and 66% specificity. MRI detected lateral meniscal tears in 50% with an 84% specificity. As such, MRI missed 10 significant meniscus ruptures requiring surgical treatment. The sensitivity for partial or total medial collateral ligament tears was 56%, the specificity 93%. Rupture of the medial retinaculum in cases with patellar dislocation or significant damage of articular cartilage were only detected by MRI in a few cases (27% and 20% sensitivity, respectively). MRIs low diagnostic validity for intraarticular pathology with hemarthrosis may be attributed to the shifting paramagnetic properties of the blood remains and catabolic processes in meniscal and chondral tissues during the hemoglobin degradation process. Accordingly, MRI, with the technique used, could neither replace arthroscopy in the diagnosis and screening of acute knee injuries, nor select patients with need for immediate arthroscopic meniscal surgery. <22> Unique Identifier 10894382 Medline Identifier 20350880 Authors Shirakura K. Terauchi M. Katayama M. Watanabe H. Yamaji T. Takagishi K. Institution Department of Orthopaedic Surgery, Gunma University Faculty of Medicine, Japan. kshiraku@akagi.sb.gunma-u.ac.jp Title The management of medial ligament tears in patients with combined anterior cruciate and medial ligament lesions. Source International Orthopaedics. 24(2):108-11, 2000. Abstract The management of patients with combined medial collateral (MCL) and anterior cruciate (ACL) rupture remains controversial. We studied 25 such patients who elected to have the ACL lesion treated conservatively; 14 underwent MCL repair with early mobilization and 11 were treated with immobilization for two weeks. The mean follow up was 5.9 years (2 to 11). There was no difference in the clinical assessment of ligamentous laxity, KT-1000 measurements or Tegner activity scores between the two groups but there were significantly higher Lysholm function scores in the operated group. <23> Unique Identifier 9109554 Medline Identifier 97263639 Authors Woo SL. Chan SS. Yamaji T. Institution Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh, PA 15213, USA. Title Biomechanics of knee ligament healing, repair and reconstruction. [Review] [68 refs] Source Journal of Biomechanics. 30(5):431-9, 1997 May. Abstract Injuries of the anterior cruciate ligament (ACL) and the medial collateral ligament (MCL) are common, accounting for 90% of all knee ligament injuries in young and active individuals. During the last decade, our research center has focused on MCL healing and ACL reconstruction. We have found that the MCL heals without intervention after an isolated injury, and that primary repair offers no apparent advantage. After a combined injury of the ACL and MCL, the ACL requires reconstruction, whereas primary repair again contributes little or nothing toward MCL healing. Midsubstance ACL injuries have limited healing ability. Hence, the treatment of choice for a torn ACL in a young, active patient is generally reconstruction with an autograft or allograft. However, the appropriate replacement graft and reconstruction technique to use are still debated. Current research efforts have been placed on investigating the magnitude and direction of in situ forces in the human ACL. We use a six-component universal force moment sensor combined with a six-degree-of-freedom (DOF) robotic manipulator to learn as well as to reproduce the six-DOF motion of the knee before and after ACL injury. This way, the in situ force in the ACL under an anterior posterior tibial load of 110 N was obtained. This methodology should make it possible to obtain the needed data to aid in better understanding of ACL reconstruction and possible development of improved clinical management. [References: 68] <24> Unique Identifier 11205863 Medline Identifier 21073836 Authors Leopold SS. McStay C. Klafeta K. Jacobs JJ. Berger RA. Rosenberg AG. Institution Rush-Presbyterian-St Luke's Medical Center, Chicago, Illinois 60612, USA. Title Primary repair of intraoperative disruption of the medical collateral ligament during total knee arthroplasty. Source Journal of Bone & Joint Surgery. 83-A(1):86-91, 2001 Jan. Abstract BACKGROUND: Intraoperative disruption of the medial collateral ligament during total knee arthroplasty is an uncommon complication that is frequently treated by implanting a prosthesis with varus-valgus constraint. To our knowledge, no data have been published on primary repair or reattachment of the medial collateral ligament and implantation of a minimally constrained posterior-stabilized or cruciate-retaining prosthesis. This retrospective study evaluates the hypothesis that satisfactory clinical results, at a minimum of two years, can be achieved with immediate repair or reattachment of the medial collateral ligament and without a constrained total knee prosthesis. METHODS: Of 600 knees treated with primary total knee arthroplasty, sixteen (in fourteen patients) sustained either a midsubstance disruption of the medial collateral ligament or an avulsion of the ligament from bone during the procedure. Preoperatively, all patients had either neutral or varus alignment and an intact medial collateral ligament. Midsubstance tears were treated with direct primary repair, and avulsions of the ligament off the tibia or femur were treated with suture-anchor reattachment to bone. All patients wore a hinged knee brace, with no limit to the range of motion, for six weeks postoperatively. Clinical and radiographic data were gathered prospectively as part of a database that was ongoing throughout the period of study; the cohort of patients was assembled retrospectively by searching that database. RESULTS: No patients were lost to follow-up. The mean duration of follow-up was forty-five months (range, twenty-four to ninety-five months). The Hospital for Special Surgery knee scores increased from a mean of 47 points (poor) preoperatively to a mean of 93 points (excellent) at the time of final follow-up. On physical examination, no patient had a Hospital for Special Surgery score in the fair or poor range and all patients had regained normal stability in the coronal plane both at full extension and at 30 degrees of flexion. No patient required knee-bracing beyond the initial six-week postoperative period. The range of motion at the time of final follow-up averaged 108 degrees (range, 85 degrees to 125 degrees ), although one knee required manipulation under anesthesia to obtain a satisfactory range of motion. No arthroplasties required revision. Radiographic examination demonstrated appropriate limb alignment in all patients at the time of final follow-up. CONCLUSIONS: Intraoperative disruption of the medial collateral ligament can be treated with primary repair or reattachment of the ligament to bone and postoperative bracing with good results; this avoids the potential disadvantages associated with the use of varus-valgus constrained implants. <25> Unique Identifier 8609106 Medline Identifier 96190455 Authors Hillard-Sembell D. Daniel DM. Stone ML. Dobson BE. Fithian DC. Institution San Diego Kaiser Medical Center, California, USA. Title Combined injuries of the anterior cruciate and medial collateral ligaments of the knee. Effect of treatment on stability and function of the joint. Source Journal of Bone & Joint Surgery. 78(2):169-76, 1996 Feb. Abstract We performed a retrospective study of sixty-six patients (forty-one male and twenty-five female) who had a combined injury of the anterior cruciate and medial collateral ligaments. Our purpose was to determine the prevalence of late valgus instability of the knee. The mean age of the patients was thirty-five years (range, sixteen to sixty-three years). The mean follow-up interval was forty-five months (range, twenty-one to 108 months). Twenty patients had been injured while snow-skiing; twentyfour, during other sports activities; seven, in a motor-vehicle accident; and the remaining fifteen, during activities of daily living. Eleven patients had reconstruction of the anterior cruciate ligament and repair of the medial collateral ligament, thirty-three had reconstruction of only the anterior cruciate ligament, and twenty-two were managed nonoperatively. There was no evidence of valgus instability on clinical examination at the most recent follow-up visit. However, there was evidence of instability on stress roentgenograms of the knee in eight (13 per cent) of sixty patients. With the numbers available, we could detect no relationship between the presence of valgus instability and the method of treatment of the ligamentous tears ( p > 0.4). We also compared the results for twenty-one of the thirty-three patients who had a combined ligamentous injury and reconstruction of only the anterior cruciate ligament with those for thirty-seven patients who had reconstruction of an isolated tear of the anterior cruciate ligament. After a mean followup interval of thirty-five months (range, twenty-one to sixty-six months), there was no difference in the anterior displacement, impairment of function, level of participation in sports activities, results of the one-leg-hop for distance test, or strength as determined by testing on a Cybex machine. On the basis of the findings in this study, we believe that, when there is mild or moderate valgus instability, an injury of the medial collateral ligament does not need to be repaired when the anterior cruciate ligament is repaired after a combined ligamentous injury. <26> Unique Identifier 10633898 Medline Identifier 20099715 Authors Eygendaal D. Olsen BS. Jensen SL. Seki A. Sojbjerg JO. Institution Department of Orthopaedic Surgery, Academic Hospital Leiden, The Netherlands. Title Kinematics of partial and total ruptures of the medial collateral ligament of the elbow. Source Journal of Shoulder & Elbow Surgery. 8(6):612-6, 1999 Nov-Dec. Abstract In this study the kinematics of partial and total ruptures of the medial collateral ligament of the elbow are investigated. After selective transection of the medial collateral ligament of 8 osteoligamentous intact elbow preparations was performed, 3-dimensional measurements of angular displacement, increase in medial joint opening, and translation of the radial head were examined during application of relevant stress. Increase in joint opening was significant only after complete transection of the anterior part of the medial collateral ligament was performed. The joint opening was detected during valgus and internal rotatory stress only. After partial transection of the anterior bundle of the medial collateral ligament was performed, there was an elbow laxity to valgus and internal rotatory force, which became significant after transection of 100% of the anterior bundle of the medial collateral ligament and was maximum between 70 degrees to 90 degrees of flexion. No radial head movement was seen after partial or total transection of the anterior bundle of the medial collateral ligament was performed. In conclusion, this study indicates that valgus or internal rotatory elbow instability should be evaluated at 70 degrees to 90 degrees of flexion. Detection of partial ruptures in the anterior bundle of the medial collateral ligament based on medial joint opening and increased valgus movement is impossible. <27> Unique Identifier 8898522 Medline Identifier 97054143 Authors Malanga GA. Smith HM. Institution Department of Physical Medicine and Rehab, Mayo Clinic, Rochester, MN 55905, USA. Title Lower extremity injuries in in-line skaters: a report of two cases. Source Journal of Sports Medicine & Physical Fitness. 36(2):139-42, 1996 Jun. Abstract In-line skating has become a very popular sport over the past several years. Previous studies examining the injuries associated with this sport have emphasized the incidence upper extremity injuries. Two cases are described in which patients suffered severe lower extremity injuries while in-line skating: one had a femoral shaft spiral fracture and the other bilateral anterior cruciate ligament and medial collateral ligament injuries. Although a predominance of upper extremity injuries associated with this sport has been widely noted, increased numbers of participants, higher speeds and changing skate designs may further predispose skaters to leg, knee and ankle injuries. <28> Unique Identifier 9604195 Medline Identifier 98267554 Authors Frolke JP. Oskam J. Institution Vierhout PA. Department of Traumatology, Free University Hospital, Amsterdam, The Netherlands. Title Primary reconstruction of the medial collateral ligament in combined injury of the medial collateral and anterior cruciate ligaments. Shortterm results. Source Knee Surgery, Sports Traumatology, Arthroscopy. 6(2):103-6, 1998. Abstract We describe our experiences with 22 patients who underwent acute surgical intervention for complete combined injury of the anterior cruciate ligament (ACL) and medial collateral ligament (MCL) in our hospital. In all patients, an arthroscopically guided repair of the MCL was performed, while the torn ACL was treated non-surgically. Primary reconstruction of the MCL in patients with complete disruptions of the MCL complex as well as the ACL reduces combined anteromedial instability to an isolated problem of the ACL. As a result of this treatment, the condition of 15 of 22 knees was improved, after an average duration of follow-up of 2 and a half years. In conclusion, our treatment strategy of an immediate repair of the MCL and reconstruction of the ACL when conservative treatment has failed seems safe and effective. <29> Unique Identifier 9728679 Medline Identifier 98396872 Authors Abdel-Rahman EM. Hefzy MS. Institution Department of Mechanical, Industrial and Manufacturing Engineering, The University of Toledo, OH 43606, USA. Title Three-dimensional dynamic behaviour of the human knee joint under impact loading. Source Medical Engineering & Physics. 20(4):276-90, 1998 Jun. Abstract The objective of this study is to determine the three-dimensional dynamic response of the human knee joint. A three-dimensional anatomical dynamic model was thus developed and consists of two body segments in contact (the femur and tibia) executing a general three-dimensional dynamic motion within the constraints of the different ligamentous structures. Each of the articular surfaces at the tibio-femoral joint was represented mathematically by a separate mathematical function. The joint ligaments were modelled as nonlinear elastic springs. The six-degrees-offreedom joint motions were characterized by using six kinematic parameters, and ligamentous forces were expressed in terms of these six parameters. Knee response was studied by considering sudden external forcing pulse loads applied to the tibia. Model equations consist of nonlinear second-order ordinary differential equations coupled with nonlinear algebraic constraint conditions. Constraint equations were written to maintain at least one-point contact throughout motion; one- and two-point contact versions of the model were developed. This Differential-Algebraic Equations (DAE) system was solved by employing a DAE solver: the Differential/Algebraic System Solver (DASSL) developed at Lawrence Livermore National Laboratory. A solution representing the response of this three-dimensional dynamic system was thus obtained for the first time. Earlier attempts to determine the system's response were unsuccessful owing to the inherent numerical instabilities in the system and the limitations of the solution techniques. Under the conditions tested, evidence of "femoral roll back" on both medial and lateral tibial plateaus was not observed from the model predictions. In the range of 20 degrees to 66 degrees of knee flexion, the lateral tibial contact point moved posteriorly while the medial tibial contact point moved anteriorly. In the range of 66 degrees to 90 degrees of knee flexion, contact was maintained only on the medial side and the tibial contact point (on the medial side) continued to move anteriorly. It was further found that increasing pulse amplitude and/or duration caused a decrease in the magnitude of the tibio-femoral contact force at a given flexion angle. These results suggest that increasing load level caused a decrease in joint stiffness. The results of this study also show that the anterior fibres of the posterior cruciate and the medial collateral ligaments are the primary restraints for a posterior forcing pulse in the range of 20 degrees to 90 degrees of knee flexion; this explains why most isolated posterior cruciate ligament injuries and combined injuries to the posterior cruciate and the medial collateral result from a posterior impact on a flexed knee. <30> Unique Identifier 11046165 Medline Identifier 20501343 Authors Recondo JA. Salvador E. Villanua JA. Barrera MC. Gervas C. Alustiza JM. Institution Department of Magnetic Resonance, Osatek, Hospital Aranzazu, Complejo Hospitalario Donostia, Paseo Doctor Beguiristain 109, 20014 San Sebastian, Spain. rm.donostia@ostatek.es Title Lateral stabilizing structures of the knee: functional anatomy and injuries assessed with MR imaging. Source Radiographics. 20 Spec No:S91-S102, 2000 Oct. Abstract The lateral aspect of the knee is stabilized by a complex arrangement of ligaments, tendons, and muscles. These structures can be demonstrated with routine spin-echo magnetic resonance (MR) imaging sequences performed in the sagittal, coronal, and axial planes. Anterolateral stabilization is provided by the capsule and iliotibial tract. Posterolateral stabilization is provided by the arcuate ligament complex, which comprises the lateral collateral ligament; biceps femoris tendon; popliteus muscle and tendon; popliteal meniscal and popliteal fibular ligaments; oblique popliteal, arcuate, and fabellofibular ligaments; and lateral gastrocnemius muscle. Injuries to lateral knee structures are less common than injuries to medial knee structures but may be more disabling. Most lateral compartment injuries are associated with damage to the cruciate ligaments and medial knee structures. Moreover, such injuries are frequently overlooked at clinical examination. Structures of the anterolateral quadrant are the most frequently injured; posterolateral instability is considerably less common. Practically all tears of the lateral collateral ligament are associated with damage to posterolateral knee structures. Most injuries of the popliteus muscle and tendon are associated with damage to other knee structures. MR imaging can demonstrate these injuries. Familiarity with the musculotendinous anatomy of the knee will facilitate accurate diagnosis with MR imaging. <31> Unique Identifier 10512209 Medline Identifier 99440760 Authors Larsen E. Jensen PK. Jensen PR. Institution Gildhoj Speciallaegeklinik, Copenhagen, Denmark. Title Long-term outcome of knee and ankle injuries in elite football. Source Scandinavian Journal of Medicine & Science in Sports. 9(5):285-9, 1999 Oct. Abstract To estimate the risk and evaluate the long-term outcome of knee and ankle injuries in former national team elite football, 69 players were randomly selected, followed by clinical and stress radiographic examinations. Thirty-nine players (49 knees) had had knee injuries and 29 ankle injuries (35 ankles). The median time from injury until study examination was 25 years. The knee injuries were tears of the medial collateral ligament (MCL) in 24 cases combined with rupture of the anterior cruciate ligament (ACL) and meniscus lesions in three. Meniscus lesions had occurred in 17 cases including three combined with ACL and MCL and another two with ACL ruptures. Isolated rupture of the ACL had occurred in four cases. The ankle lesions were in 26 of 35 cases ruptures of the lateral ligaments. In all, 12 players had completely stopped football and three had changed occupation. Signs of arthritis were present in 63% of the injured knees and in 33% of the injured ankles. The incidence of arthritis in the group of 17 uninjured players was 26% in the knee and 18% the ankle. In elite football players knee and ankle injuries seem to have a serious long-term outcome, but also uninjured players have a higher risk of developing arthritis than the normal population. <32> Unique Identifier 10591931 Medline Identifier 20059954 Authors Patel JJ. Institution Department of Radiology, Baystate Medical Center, 759 Chestnut Street, Springfield, MA 01199, USA. Title Intra-articular entrapment of the medial collateral ligament: radiographic and MRI findings. Source Skeletal Radiology. 28(11):658-60, 1999 Nov. Abstract Displacement of the medial collateral ligament (MCL) into the medial knee joint is an extremely rare finding associated with MCL tears, and is easily diagnosed on magnetic resonance imaging. A case of intra-articular interposition of the MCL during a severe knee injury is presented. A radiolucent "fat stripe" sign and adjacent skin dimpling on radiographs may be relatively specific indicators of this injury.