Appendix 4

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Amendment Appendix 4 (rev 9-08)

TO BE COMPLETED FOR ALL SURGERY PROJECTS

Check all that apply to your amendment ( IACUC Guideline 13 )

Species Type of Surgical Procedure

Terminal (non-survival) surgery

Survival surgery (once per animal)

Multiple survival surgery

Non-survival second surgery

Check (x) and provide appropriate location of surgery:

SOM-ULAR Surgery- Richards 7 th

floor Surgery Suite

SOM-ULAR Surgery- Stemmler 5 th floor Surgery Suite

SOM-ULAR BRB 3 Surgery Suites

SOM-ULAR Glenolden Surgery Suites

SVM-VHUP 4115 Surgery

SVM-Student 296E

Animal Facility Rodent Procedure Room Bldg/Rm Number:

Investigator’s Lab. Bldg/Rm Number:

If other, specify

1.

List the names, roles, training and years of experience of those who will perform the surgery.

Name Role in the Procedure Years Experience with

Procedure

Note: The Principal Investigator is responsible for the training of all personnel participating in the study. If individual training is necessary for a particular procedure, please contact ULAR staff for training.

2.

PRE-OPERATIVE FASTING

Will food be withheld?

If yes, for how long?

Yes

Will water be withheld?

If yes, for how long?

Yes

No

No

Amendment Appendix 4 (rev 9-08)

3.

PRE-ANESTHETIC/ANALGESIC, ANESTHETIC AGENTS & INTRA-

OPERATIVE ANALGESIC

Species Preanesthetic agent mg/kg

Pre- analgesic agent mg/kg

Anesthetic:

Induction

Dose (mg/kg or % gas)

Anesthetic:

Maintenance

Dose (mg/kg or % gas)

Intra-

Operative

Analgesic mg/kg

Route a.

Describe how you will determine depth of anesthesia and how it will be increased if necessary. b.

Describe the surgical procedure. Include descriptions regarding preparation for the surgical procedure (e.g. techniques used for skin prep, instrument prep, surgeon prep, etc), anesthesia, peri-operative analgesia, actual procedure, and the method of closure. c.

Do you anticipate the possibility of sudden death during the post-operative period?

NO YES.

If yes, please describe, including why this is the case, the expected mortality rates and any actions taken to limit mortality

4.

POSTOPERATIVE CARE : a.

Provide a description of the post-surgical care, include that provided immediately postoperatively and long-term. Include objective criteria that are suggestive of post-operative pain, the frequency and time course of observations, and the person(s) who are responsible for post-operative care.

Are analgesics administered? Yes No (If no, justify why not; If yes, complete chart)

Post Operative Analgesics and Sedatives and Antibiotics

Species Agent Dose mg/kg & Route Frequency of Adm.

Amendment Appendix 4 (rev 9-08)

5.

Will multiple survival surgery be required? Yes No

If yes, ” give a detailed justification for the necessity of the multiple survival surgeries. If they differ from the original surgery, please describe them in detail. What is the time interval between the surgeries?

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