Characterizations of Particle Size Distribution of the Droplets Exhaled by Sneeze Z.Y. Han, W.G. Weng, Q.Y. Huang Supplementary Material 1 Time stability of the sneeze droplet size distribution. In this experiment, the sampling frequency was set as 2.5 kHz. The size distribution of the spray would be measured and recorded every 0.4ms. And so the time stability of the droplet size distribution for each sneeze is also studied. Figs. S1 and S2 demonstrate the size distribution of sneeze droplets measured at 100ms, 200ms, 300ms, 400ms, 500ms and 600ms after the sneeze begin, for unimodal and bimodal distributions respectively. As shown in Figs. S1 and S2, the volume-based size distribution measured at different time during a sneeze is similar, both for unimodal and bimodal distributions. This result proves that the distribution characteristic of sneeze droplets will remain almost the same in the duration of the sneeze, both for unimodal and bimodal distributions. Fig. S1 Volume-based size distribution measured at different time in the duration of one sneeze (unimodal distribution). Fig. S2 Volume-based size distribution measured at different time in the duration of one sneeze (bimodal distribution). 2 Average number size distribution of sneeze droplets According to the calculation method proposed in this work, the number size distribution of the droplets of all the forty-four sneezes can be calculated, both for unimodal and bimodal distributions. The average number size distribution can be calculated for the two types of distributions, respectively. Detailed information of the calculated average number size distribution is given in Table S1 and S2. Table S1. The average number size distribution of the unimodal size distribution Size class (μm) Quantity Proportion (averaged per person) Standard deviation <100 100.0~116.6 116.6~135.9 135.9~158.5 158.5~184.8 184.8~215.4 215.4~251.2 251.2~292.9 292.9~341.5 341.5~398.1 398.1~464.2 464.2~541.2 541.2~631.0 631.0~735.6 735.6~857.7 857.7~1000.0 <0.005 0.007988 0.010455 0.012922 0.022143 0.044248 0.078955 0.115100 0.140896 0.150130 0.141863 0.117941 0.083330 0.047723 0.020718 0.005588 / 0.016852 0.024912 0.030314 0.032966 0.039646 0.047411 0.049041 0.038497 0.027529 0.042390 0.055308 0.049051 0.030705 0.013904 0.004269 Table S2. The average number size distribution of the bimodal size distribution Size class (μm) Quantity Proportion (averaged per person) Standard deviation <21.5 21.5~25.1 25.1~29.3 29.3~34.1 34.1~39.8 39.8~46.4 46.4~54.1 54.1~63.1 63.1~73.6 73.6~85.8 85.8~100.0 100.0~116.6 116.6~135.9 135.9~158.5 158.5~184.8 184.8~215.4 215.4~251.2 251.2~292.9 292.9~341.5 341.5~398.1 398.1~464.2 464.2~541.2 541.2~631.0 631.0~735.6 735.6~857.7 857.7~1000.0 <0.005 0.006572 0.013065 0.021522 0.055594 0.065905 0.085975 0.109173 0.132693 0.144683 0.134911 0.100702 0.058045 0.026841 0.010709 0.004418 0.003003 0.003528 0.004513 0.004989 0.004700 0.003765 0.002533 0.001398 0.000599 0.000164 / 0.017948 0.034184 0.048413 0.068620 0.072299 0.069034 0.049518 0.037744 0.062749 0.077350 0.069915 0.048540 0.025886 0.010625 0.003878 0.002008 0.002379 0.003439 0.004937 0.004418 0.003781 0.002695 0.001575 0.000713 0.000202 3 Results of Linear Regression Analysis By using Linear Regression Analysis, the relationships between the distribution parameters of the volume-based size distribution and each physiological characteristic of the subjects are 2 investigated. And the P-value and adjusted R value can be obtained to test the significance level and goodness of the fitting results. The fitting results show that the significant correlation can be found between the variance of peak 1, and the height and weight of the subjects (P-value <0.02), and also between the mean of peak 2, with the height and weight of the subjects (P-value <0.04). Fig. S3 shows the fitting results and the fitting curves to demonstrate the correlation. However, although significant correlation can be found, the average values of the means and variances in this work can also be used for approximate evaluation of the volume-based size distribution of an adult. Fig. S3 Relationships between the size distribution parameters of sneeze droplets and the physiological characteristics of the subjects: (a) Relationships between the height and the variance of bimodal distribution of Peak 1; (b) Relationships between the weight and the variance of bimodal distribution of Peak 1; (c) Relationships between the height and the mean of bimodal distribution of Peak 2; (d) Relationships between the weight and the mean of bimodal distribution of Peak 2.