MATERIAL SAFETY DATA SHEET DOC NO. 20300 PAGE 1/9 MicroSi part number: CEM 388SS SECTION 1- COMPANY AND PRODUCT IDENTIFICATION PREPARED BY: MICROSI, INC. 10028 S. 51ST ST. PHOENIX, AZ 85044 MANUFACTURER: EMERGENCY TELEPHONE: (800) 424-9300 (CHEMTREC) (480) 893-8898 (INFORMATION) MICROSI, INC. 10028 S. 51ST ST, PHOENIX, AZ 85044 TELEPHONE FOR INFORMATION: (480) 893-8898 PREPARED 08/17/98 REVISED 3/12/03 PRODUCT NAME: CHEMICAL NAME: CEM 388SS CONTRAST ENHANCEMENT MATERIAL SECTION 2 COMPOSITION CHEMICAL FAMILY: FORMULA: MIXTURE MIXTURE APPROX % ACGIH TLV OSHA PEL NIOSH REL CAS NO. PROPYLENE GLYCOL METHYL ETHER ACETATE ISOPROPYL ALCOHOL >70 None None None 108-65-6 <6 67-63-0 <15 400 ppm 980 mg/m3 500 ppm STEL 1225 mg/m3 None 400 ppm 8 hr TWA 500 ppm STEL TRADE SECRET COMPONENT 1** TRADE SECRET COMPONENT 2 400 ppm 980 mg/m3 500 ppm STEL 1225 mg/m3 None <9 None None None PRODUCT COMPOSITION None Some items on this MSDS may be designated as trade secrets. Bonafide requests for disclosure of trade secret information to medical personnel must be made in accordance with the provisions contained in 29 CFR 1910.1200 I 1-13. **Note: Review Section 11, Toxicological Information, for data on this Trade Secret Component 1. MATERIAL SAFETY DATA SHEET PAGE 2/9 CEM 388SS SECTION 3 HAZARDS IDENTIFICATION HAZARD CLASSIFICATION: FIRE AND EXPLOSION: POTENTIAL HEALTH EFFECTS: INGESTION: INHALATION: SKIN CONTACT: FLAMMABLE LIQUID (BASED ON IMO) NONE MAY BE HARMFUL IF SWALLOWED NONE KNOWN MAY CAUSE MILD IRRITATION, PROLONGED SKIN CONTACT MAY CAUSE DERMATITIS EYE CONTACT: EYE IRRITATION MAY RESULT MEDICAL CONDITIONS AGGRAVATED: UNKNOWN CHRONIC EFFECTS OF OVEREXPOSURE: NONE KNOWN Propylene Glycol Methyl Ether Acetate European Community Hazards Identification: R: 10-36 R10—Flammable R36—Irritant to eyes. S: 2-25 S2 — Keep out of the reach of Children. S25 --Avoid contact with eyes. Danger Symbol(s): Xi -- Irritant Isopropyl Alcohol R: 10-36 R11—Highly flammable R36—Irritant to eyes. R67 –Vapors may cause drowsiness and dizziness. S: 2-25 S2 —Keep out of the reach of Children. S7 —Keep Container Tightly Closed S16—Keep away from sources of ignition. No smoking. S24—Avoid contact with skin. S25—Avoid contact with eyes. S26 --In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Danger Symbol(s): Xi Irritant F Flammable SECTION 4 FIRST AID MEASURES INHALATION: SKIN CONTACT: EYE CONTACT: INGESTION: REMOVE TO FRESH AIR, IF NOT BREATHING GIVE ARTIFICAL RESPIRATION, PREFERABLY MOUTH-TO-MOUTH. IF BREATHING IS DIFFICULT, GIVE OXYGEN. GET MEDICAL ATTENTION. IMMEDIATELY FLUSH SKIN WITH PLENTY OF SOAP AND WATER FOR AT LEAST 15 MINUTES. GET MEDICAL ATTENTION. REMOVE CONTAMINATED CLOTHING AND LAUNDER BEFORE USE. IMMEDIATELY FLUSH EYES WITH PLENTY OF WATER FOR AT LEAST 15 MINUTES. GET MEDICAL ATTENTION IF IRRITATION PERSISTS. IF SWALLOWED DO NOT INDUCE VOMITING, GIVE LARGE QUANTITIES OF WATER TO DRINK. NEVER GIVE ANYTHING TO AN UNCONSCIOUS PERSON. GET MEDICAL ATTENTION IMMEDIATELY. MATERIAL SAFETY DATA SHEET PAGE 3/9 CEM 388SS SECTION 5 FIRE FIGHTING MEASURES FLASH POINT: 26 C (80 F) FLAMMABLE LIMITS IN AIR (%): LOWER 1.3, UPPER 13.1 EXTINGUISHING MEDIA: ALL STANDARD FIREFIGHTING MEDIA SPECIAL FIREFIGHTING PROCEDURES: WEAR RESPIRATORY PROTECTION IF IN A CONFINED AREA UNUSUAL FIRE AND EXPLOSION HAZARDS: NONE SECTION 6 ACCIDENTAL RELEASE MEASURES ACTION TO BE TAKEN IF MATERIAL IS RELEASED OR SPILLED: WIPE, SOAK UP IN AN INERT MATERIAL SCRAPE UP AND PUT IN A CONTAINER FOR DISPOSAL WEAR PROPER PROTECTIVE EQUIPMENT AS SPECIFIED IN THE PROTECTIVE EQUIPMENT SECTION WARN OTHER WORKERS OF SPILL DISPOSAL METHOD: DISPOSAL SHOULD BE MADE IN ACCORDANCE WITH FEDERAL, STATE AND LOCAL REGULATIONS. INCINERATION RECOMMENDED. SECTION 7 HANDLING AND STORAGE KEEP CONTAINER CLOSED WHEN NOT IN USE STORE UPRIGHT IN A COOL PLACE BETWEEN 18C – 24C (65F - 75F) AVOID CONTACT WITH SKIN AND EYES WASH HANDS BEFORE EATING OR SMOKING DO NOT INALE VAPORS USE IN A WELL VENTILATED AREA EXHAUST VENTILATION SHOWERS EYEWASH STATIONS INFORMATION ON EMPTIED CONTAINER DO NOT REUSE THIS CONTAINER THIS CONTAINER MAY BE HAZARDOUS WHEN EMPTIED RESIDUES WILL BE EXPLOSIVE OR FLAMMABLE KEEP AWAY FROM HEAT, SPARKS AND FLAME DO NOT PUNCTURE OR CUT THIS CONTAINER, AND DO NOT WELD ON OR NEAR THIS CONTAINER SECTION 8 EXPOSURE CONTROLS/PERSONAL PROTECTION EXPOSURE GUIDELINES: REFERENCE SECTION 2 COMPOSITION. RESPIRATORY PROTECTION: USE APPROVED RESPIRATORY PROTECTION VENTILATION: USE ONLY IN WELL-VENTILATED AREA PROTECTIVE GLOVES: RUBBER GLOVES EYE AND FACE PROTECTION: SAFETY GLASSES; CHEMICAL GOGGLES MATERIAL SAFETY DATA SHEET PAGE 4/9 CEM 388SS SECTION 8 EXPOSURE CONTROLS/PERSONAL PROTECTION CONTINUED OTHER PROTECTIVE CLOTHING OR EQUIPMENT: WEAR EYE PROTECTION AND PROTECTIVE CLOTHING WORK/HYGIENE PRACTICES: AVOID BREATHING VAPOR AVOID CONTACT WITH EYES, WASH HANDS AND FACE AFTER HANDLING SECTION 9 PHYSICAL AND CHEMICAL PROPERTIES BOILING POINT: VAPOR PRESSURE (20 C): VAPOR DENSITY (AIR=1): SPECIFIC GRAVITY: MELTING POINT: EVAPORATION RATE: SOLUBILITY IN WATER: APPEARANCE - COLOR: APPEARANCE - FORM: ODOR: ~125 C 3.7MM HG NA ~. 95 NF >1 NA YELLOW LIQUID SLIGHT SECTION 10 STABILITY AND REACTIVITY STABILITY: CONDITIONS TO AVOID: INCOMPATIBILITY (MATERIALS TO AVOID): HAZARDOUS DECOMPOSITION PRODUCTS: HAZARDOUS POLYMERIZATION: STABLE HEAT, SPARKS, AND OTHER SOURCES OF IGNITION OXIDIZING AGENTS, HALOGENS, ACIDS, AMINES, LIGHT CARBON MONOXIDE, CARBON DIOXIDE, FUMES OF AROMATIC HYDROCARBONS WILL NOT OCCUR SECTION 11 TOXICOLOGICAL INFORMATION Chemical Name: Propylene Glycol Methyl Ether Acetate (PGMEA) RTECS Number (Registry of Toxic Effects of Chemical Substances): CAS Number: EEC Number EEC Index number: Acute Effects: Causes Skin Irritation Causes Eye Irritation Chronic Effects: Target Organs: Liver and Kidney Ames Assay Test: No Data NTP (National Toxicology Program): Not Listed IARC (International Agency for Reach on Cancer): Not Listed AI8925000 108-65-6 203-603-9 607-195-00-7 MATERIAL SAFETY DATA SHEET PAGE 5/9 CEM 388SS SECTION 11 TOXICOLOGICAL INFORMATION CONTINUED Toxicity Data Route |Organism| Dose | Source RTE | ORGN | DOSE | SOURCE ===============+========+=========+========= oral |rat |LD50 8532|DOWCC* | |mg/kg |MSD-1582 ---------------+--------+---------+--------Intraperitoneal|mouse |LD50 750 |NTIS** | |mg/kg |AD691-490 ---------------+--------+---------+--------skin |rabbit |LD50 >5 |DOWCC* | |g/kg |MSD-1582 TOXICITY DATA REFERENCES: DOWCC* Dow Chemical Company Reports (Dow Chemical USA, Health and Environment Research, Toxicology Research Lab., Midland, MI 48640) NTIS** National Technical Information Service (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Other Multiple Dose Data OEL-AUSTRIA: MAK 50 ppm (275 mg/m3), JAN1999 OEL-DENMARK: TWA 50 ppm (270 mg/m3), JAN1999 OEL-SWEDEN: NGV 50 ppm (230 mg/m3), KTV 75 ppm (350 mg/m3, Skin, JAN19 99 OEL-UNITED KINGDOM: TWA 50 ppm (274 mg/m3), STEL 150 ppm (822 mg/m3), SEP2000 Chemical Name: Isopropyl Alcohol (IPA) RTECS Number (Registry of Toxic Effects of Chemical Substances): CAS Number: EEC Number EEC Index number: NT8050000 67-63-0 200-661-7 603-117-00-0 Acute Effects: Eye Irritant Respiratory Irritant Chronic Effects: Target Organs: Respiratory system, Central Nervous System Ames Assay Test: No Data NTP (National Toxicology Program): Not Listed IARC (International Agency for Reach on Cancer): Group 3 Unclassifiable as to carcinogenicity to humans. MATERIAL SAFETY DATA SHEET PAGE 6/9 CEM 388SS SECTION 11 TOXICOLOGICAL INFORMATION CONTINUED Toxicity Data |oral |rat |LD50 5045 | |GISAAA | | |mg/kg | |43(1),8,19 | | | | |78 -----------+---------------+------------+-----------+--------+---------|inhalation |rat |LC50 |8H |NPIRI* | | |1.6000E+04 | |1,100,1974 | | |ppm | | -----------+---------------+------------+-----------+--------+---------|intraperitoneal|rat |LD50 2735 | |EVHPAZ | | |mg/kg | |61,321,198 | | | | |5 -----------+---------------+------------+-----------+--------+---------|intravenous |rat |LD50 1088 | |EVHPAZ | | |mg/kg | |61,321,198 | | | | |5 -----------+---------------+------------+-----------+--------+---------|oral |mouse |LD50 3600 | |GISAAA | | |mg/kg | |43(1),8,19 | | | | |78 -----------+---------------+------------+-----------+--------+---------|oral |rabbit |LD50 6410 | |FAONAU | | |mg/kg | |48A,114,19 | | | | |70 -----------+---------------+------------+-----------+--------+---------|skin |rabbit |LD50 | |NPIRI* | | |1.2800E+04 | |1,100,1974 | | |mg/kg | | -----------+---------------+------------+-----------+--------+---------|intraperitoneal|rabbit |LD50 667 | |EVHPAZ | | |mg/kg | |61,321,198 | | | | |5 -----------+---------------+------------+-----------+--------+---------|intravenous |rabbit |LD50 1184 | |EVHPAZ | | |mg/kg | |61,321,198 | | | | |5 -----------+---------------+------------+-----------+--------+---------|intraperitoneal|guinea pig |LD50 2560 | |EVHPAZ | | |mg/kg | |61,321,198 | | | | |5 -----------+---------------+------------+-----------+--------+---------|intraperitoneal|hamster |LD50 3444 | |EVHPAZ | | |mg/kg | |61,321,198 | | | | |5 TOXICITY DATA REFERENCES: GISAAA Gigiena i Sanitariya For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.11936NPIRI* Raw Material Data Handbook, Vol 1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) EVHPAZ EHP, Environmental Health Perspectives (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.11972FAONAU FAO Nutrition Meetings Report Series (Rome, Italy) No.-57, 1948-77. Discontinued. Only Selected Registry of Toxic Effects of Chemical Substances (RTECS) data is presented here. See actual entry in RTECS for complete information. **Trade Secret Component 1 – Mutagenic effects: Positive in the Ames test. 1999/45/EC Annex II Reference Section 3 HAZARDS IDENTIFICATION MATERIAL SAFETY DATA SHEET PAGE 7/9 CEM 388SS SECTION 12 ECOLOGICAL INFORMATION BIODEGRADATION: BIOACCUMULATION: AQUATICTOXICITY: 1999/45/EC Annex III NO INFORMATION IS AVAILABLE NO INFORMATION IS AVAILABLE NO INFORMATION IS AVAILABLE No Environmental hazards SECTION 13 DISPOSAL CONSIDERATIONS CAN BE BURNED IN A CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER . DO NOT DISPOSE OF THE EMPTIED CONTAINER UNLESS THE CONTENTS HAVE BEEN COMPLETELY REMOVED AND THE CONTAINER HAS BEEN FLUSHED AND THEN DRIED. DO NOT DISPOSE OF THE EMPTIED CONTAINER UNLAWFULLY. OBSERVE ALL FEDERAL, STATE, AND LOCAL LAWS. SECTION 14 TRANSPORTATION INFORMATION DOT SHIPPING NAME: DOT HAZARD CLASS: DOT LABEL(S): UN/NA NUMBER: PLACARDS: RESIN SOLUTION FLAMMABLE LIQUID FLAMMABLE LIQUID UN1866 FLAMMABLE LIQUID EXPORT: RESIN SOLUTION UN1866 EPA HAZARD WASTE: OSHA HAZARD CLASS: CPSC CLASSIFICATION: TRANSPORTATION CLASS: NA FLAMMABLE LIQUID NA IMO 3.3 FLAMMABLE RID(OCTI) FLAMMABLE ADR(ECE) FLAMMABLE RAR(IATA) FLAMMABLE NFPA/HMIS CLASSIFICATION: FLAMMABILITY 3, REACTIVITY 0, HEALTH 2 SECTION 15 REGULATORY INFORMATION TOXIC SUBSTANCES CONTROL ACT (TSCA) STATUS: THE INGREDIENTS CONTAINED IN THIS PRODUCT ARE COMPLIANT WITH TSCA REGULATIONS. THIS PRODUCT SHOULD BE USED IN COMPLIANCE WITH LOW VOLUME EXEMPTIONS UNDER TSCA. SUPERFUND AMENDMENTS AND REAUTHORIZATION ACT OF 1986 (SARA) TITLE III SECTION 313 SUPPLIER NOTIFICATION: THIS REGULATION REQUIRES SUBMISSION OF ANNUAL REPORTS OF TOXIC CHEMICAL(S) THAT APPEAR IN SECTION 313 OF THE EMERGENCY PLANNING AND COMMUNITY RIGHT TO KNOW ACT OF 1986 AND 40 CFR 372. THIS INFORMATION MUST BE INCLUDED IN ALL MSDSs THAT ARE COPIED AND DISTRIBUTED FOR THE MATERIAL. THE TOXIC CHEMICALS CONTAINED IN THIS PRODUCT ARE: NONE CALIFORNIA PROPOSITION 65: THIS REGULATION REQUIRES A WARNING FOR CALIFORNIA PROPOSITION 65 CHEMICAL (S) UNDER THE STATUTE. THE CALIFORNIA PROPOSITION 65 CHEMICAL (S) CONTAINED IN THIS PRODUCT ARE: NONE MATERIAL SAFETY DATA SHEET PAGE 8/9 CEM 388SS SECTION 15 REGULATORY INFORMATION CONTINUED STATE RIGHT-TO-KNOW: MASSACHUSETTS RIGHT-TO-KNOW, SUBSTANCE LIST (MSL) HAZARDOUS SUBSTANCES AND EXTRAORDINARILY HAZARDOUS SUBSTANCES ON THE MSL MUST BE IDENTIFIED WHEN PRESENT IN PRODUCTS. COMPONENTS PRESENT IN THIS PRODUCT AT A LEVEL WHICH COULD REQUIRE REPORTING UNDER THE STATUTE ARE: HAZARDOUS SUBSTANCES (> 1%) UPPER BOUND CHEMICAL CAS NUMBER CONCENTRATION % NONE PENNSYLVANIA RIGHT-TO-KNOW, SUBSTANCE LIST (MSL) HAZARDOUS SUBSTANCES AND EXTRAORDINARILY HAZARDOUS SUBSTANCES ON THE MSL MUST BE IDENTIFIED WHEN PRESENT IN PRODUCTS. COMPONENTS PRESENT IN THIS PRODUCT AT A LEVEL WHICH COULD REQUIRE REPORTING UNDER THE STATUTE ARE: HAZARDOUS SUBSTANCES (> 1%) UPPER BOUND CHEMICAL CAS NUMBER CONCENTRATION % NONE This product has been reviewed for compliance with the following European Community Directives: Directive 67/548/EEC, Directive 2001/59/EC, Directive 1999/45/EC, Directive 91/155/EC, and Directive 2001/58/EC. COMPONENT PGMEA COMPONENT Isopropyl Alcohol EINEC/ELINC NUMBER EINEC/ELINC STATUS CMR CLASSIFICATION DANGER SYMBOL RISK PHRASE NUMBER SAFETY PHRASE NUMBER WGK 203-603-9 LISTED Not Classified Xi R10, R36 S2, S25 0 EINEC/ELINC NUMBER EINEC/ELINC STATUS CMR CLASSIFICATI ON DANGER SYMBOL RISK PHRASE NUMBER SAFETY PHRASE NUMBER WGK 200-661-7 LISTED Not Classified F, Xi R11, R36-67 S2, S7-16-24, 25-26 0 Note: A component of Trade Secret 1 is not listed in EINICS. All other components of this product are listed in EINICS. EINECS: European Inventory of Existing Commercial Chemical Products. ELINCS: European List of Notified Chemical Substances MATERIAL SAFETY DATA SHEET PAGE 9/9 CEM 388SS SECTION 16 OTHER INFORMATION FOR INDUSTRIAL USE ONLY THIS MATERIAL SAFETY DATA SHEET IS OFFERED SOLELY FOR YOUR INFORMATION, CONSIDERATION AND INVESTIGATION. THE DATA DESCRIBED IN THIS MSDS CONSIST OF DATA ON LITERATURE, OUR ACQUISITIONAL DATA AND ANALOGICAL INFERENCE BY DATA OF SIMILAR CHEMICAL SUBSTANCES OR PRODUCTS. SHIN-ETSU CHEMICAL CO. LTD. PROVIDES NO WARRANTIES, EITHER EXPRESSED OR IMPLIED, AND ASSUMES NO RESPONSIBILITY FOR THE ACCURACY OR COMPLETENESS OF THE DATA CONTAINED HEREIN. ADDITIONAL INFORMATION THIS DATA IS OFFERED IN GOOD FAITH AS TYPICAL VALUES AND NOT AS A PRODUCT SPECIFICATION. NO WARRANTY, EITHER EXPRESSED OR IMPLIED, IS MADE. THE RECOMMENDED HANDLING PROCEDURES ARE BELIEVED TO BE GENERALLY APPLICABLE. HOWEVER, EACH USER SHOULD REVIEW THESE RECOMMENDATIONS IN THE SPECIFIC CONTENT OF THE INTENDED USE.