(16.Juli 2007)
Program:
Ion Beams in Biology and Medicine
11th HCPMB-Workshop
Annual conference of the German-Swiss Association for Radiation
Protection
Joint GAST Conference
* invited speakers
Wednesday, September 26th, 2007
Radiation Safety
Morning session
9.00 - 9.15
Welcome
9.15 - 10.00
Opening Lecture
10.30 - 11.00
11.00 -11.30
11.30 - 12.00
12.00 -12.30
Afternoon session
14:00 - 14.30
Poster report 1:
N.N.
Chairmen: G. Kraft (GSI), O. Jäkel
(DKFZ)
J. Debus
E. Hall (Columbia)*
10.00 – 10.30 coffee
D. Schardt (GSI)*
A. Fuchs (PSI)*
G. Fehrenbacher (GSI)*
J. Griebel (BFS
München)*
12.30 – 14.00 lunch
Particle physics
Eursch (IWB, München)
M. Hultquist (Sweden)
P. Kundrat (Czech
Republic)
G. Dollinger (Universität
der Bundeswehr)
The Impact of New Technologies on the
Incidence of Second Cancers in
Radiotherapy
Neutrons and other secondary products
Radiation protection of personal &
environment
Shielding design for Ion beam therapy
Clinical research versus patient care:
Legal regulations for particle
therapy
Chairmen: T. Otto (CERN), K. Henrichs
(Siemens, München)
Improved Radiation Protection for Manual
Tasks by the Use of an Immersive Camera
System and the Technology of Augmented
Reality
Secondary doses to patient in light ion
therapy – Monte Carlo studies coupled
with anthropomorphical phantoms.
-Probabilistic two-stage model of cell
killing by ionizing radiation
-Modeling the biological effectiveness of
radiations of different qualities
Does radio biological effectiveness change
in laser driven ion therapy?
14.30 - 14.50
I. Gudowska (Sweden)
14.50 - 15.10
I. Jadrníčková (Prague)
15.10 - 15.30
Ö. Kartal (DKFZ, IMPS)
16.00 - 16.20
15.30 – 16.00 coffee
Biology Session 1
B. Jakob (GSI)
16.20 - 16.40
16.40 - 17.00
V. Hable (UniBw
München)
J. Splinter (GSI)
17.00 - 17.20
Y. Schweinfurth (GSI)
17.20 - 17.40
C. Baumstark-Khan
(DLR)
S. Ritter (GSI)
17.40 - 18.00
Dinner session
Verification of the multiple scattering and
energy for therapeutic light ion beams
implemented in a semi-analytical pencil
beam model and the MC code SHIELDHIT; benchmark with experiments
Spectrometry of LET using track-etch
detectors – Fragmentation studies and
radiobiological effectiveness in heavier
ion beams
Studying the secondary electron fluence in
12C ion beams by means of an
extrapolation chamber
Dynamics of DNA double strand breaks
detected by live cell microscopy indicates
only limited cluster formation after high
LET ionizing radiation.
Micro Irradiation of Living Cells at
SNAKE
Heavy Ions vs. UV Laser Microirradiation
– Two systems to induce localized DNA
lesions in living cells
Measurements of DNA-double strand
breaks after tumour therapy-related carbon
irradiation and comparison with γH2AX
analysis after induction of highly complex
DNA-lesions
Genotoxicity of Heavy Ions in
Recombinant Bacteria
Cytogenetic damage induced in vivo by
high and low LET radiation:
follow up of radiotherapy patients
Reception, Industry
Exhibition and poster
viewing
Thursday, September 27th, 2007
Physics + Dosimetry
Morning session
9.00 - 9.30
9.30 - 9.50
J. Pawelke (FZD)*
F. Sommerer (CERN)
9.50 - 10.10
J. Kempe (Sweden)
10.40 - 11.10
10.10 – 10.40 coffee
C. Karger (DKFZ)*
Chairmen: N. Saito (GSI), S. Brons (GSI,
HIT)
Therapy monitoring with PET techniques
Experiments and Simulations for In-beam
PET Monitoring with Oxygen Beams
Analytical transport expressions and
absorbed dose distribution of β+ emitters
in light ion radiation therapy
Dosimetry of Carbon RT Instrumentation
11.10 - 11.30
11.30 - 12.00
12.00 -12.20
N. Bassler (DKFZ)
M. Durante (Naples)*
O. Kavatsyuk (GSI)
Antiproton Radiation Dosimetry
Radiobiology for space research
Particle-induced phosphene stimulation in
heavy-ion tumor therapy
12.20 – 14.00 lunch
Afternoon session
14:00 - 14.20
Maruyama (Japan)
14.20 - 14.40
M. Rebisz (GSI)
14.40 - 15.10
C. Bert (GSI)
15.10 – 15.30
N. Saito (GSI)
16.00 - 17.00
Round table
17.00 - 17.30
Poster report 2:
N.N.
15.30 – 16.00 coffee
G. Kraft (GSI)
(Moderator)
C. Bert (GSI)
S. Webb (Royal Marsden)
S. Minohara (NIRS,
Japan)
C. Bert (GSI)
K. Henkner (DKFZ)
A. Schmidt (GSI)
17.30 - 18.00
T. Haberer (HIT)
Dinner session
at the HIT facility
HIT guided tours /
barbecue
Chairmen: Karger (DKFZ), Durante
(Naples)
Analysis of the Factors that Disturb Dose
Concentration in Carbon Beam Therapy
Diamond detectors for heavy-ion beams
dosimetry
Integrated 3D Online Motion
Compensation system for scanned carbon
ion therapy
Technical improvement of the 3D-Online
Motion Compensation System for scanned
ion beam therapy
Treatment of moving organs
Gating with scanned carbon beams
Monte Carlo Depth-Dose Calculations for
different I-Values in Heavy Ion Therapy
Cell survival studies in the presence of
target motion
Physical aspects of an ion application and
Introduction to HIT facility
Friday, September 28th, 2007
Morning session
9.00 - 9.30
9.30 - 10.00
10.30 - 11.00
11.00 - 11.30
11.30 - 12.00
Poster report 3:
N.N.
Radiobiology
M. Löbrich (Homburg)*
D. Bettega (Milano)*
10.00 – 10.30 coffee
M. Scholz (GSI)*
P. Peschke (DKFZ)*
C. Hellweg (DLR)
J. Czub (Poland)
C. Fournier (GSI)
Chairmen: M. Beuve (IPNL, CNRS),
G. Dollinger (Universität der
Bundeswehr)
Molecular biology of ion beams
Cell transformation
Biological aspects of carbon RT
Normal tissue toxicity
High-LET ion beams activate the
transcription factor NF-κB in human cells
Heavy ion radiobiological studies in the
Bragg Peak region
Fate of human fibroblasts following
C. Fürweger (Wien)
H. Hromčíkova(Czech
Republic)
M. Davídková (Czech
Republic)
R. Lee (GSI)
12.00 - 12.30
Poster report 4:
N.N.
M. Hollmark (Sweden)
M. Maalouf (France)
A. Meijer (Sweden)
T. Pouthier (GSI)
C. Schicker (GSI)
Afternoon session
12.30 – 14.00 lunch
Treatment planning
14:00 - 14.20
C. Karger (DKFZ)
14.20 -14.40
T. Elsässer (GSI)
14.40 - 15.00
M. Beuve (IPNL, CNRS)
15.00 – 15.30 coffee
O. Jäkel (DKFZ)*
M. Krämer (GSI)*
N.N.
J. Debus (Moderator)
H. Tsujii (NIRS, Japan)
B. Didinger (Heidelberg)
15.30 - 16.00
16.00 - 16.30
16.30 - 17.00
17.00 - 18.00
Round table
exposure to low and high LET irradiation:
senescence or genetic instability?
Early Cellular Signalling after Exposure
to Particles of High Linear Energy
Transfer (LET)
Analysis of repair processes in different
hamster cell lines exposed to carbon
irradiation
Effect of oxygen on DNA damage caused
by ionizing radiation of different quality
Estimating the genotoxic effects of Feions: impact of cell cycle effects,
apoptosis and intra-individual variability
Comparison of radiobiological models for
light ion therapy
Different cell death pathways for radiosensitive and radio-resistant Head and
Neck Squamous Carcinomas Cells
exposed to high and low LET radiation:
Implications for future clinical application
in hadron therapy
Apoptotic and cell cycle responses in the
small cell lung cancer cell line U-1690
following exposure to different LET of
boron and nitrogen ions
Studies on bystander effect using the GSI
heavy ion microbeam
OER Measurements in an Extended
Volume
Chairmen: M. Löbrich (Homburg),
A .Friedl (LRZ Uni München)
Measurement of relative biological
effectiveness (RBE) and fractionation
ratios (α/β) after single and fractionated
doses of carbon ions to the spinal cord of
the rat
Dependence of Cell Survival after Carbon
irradiation on the α/β-ratio for photon
irradiation – Implications of the Local
Effect Model
Theoretical limits of Local Effect Model
Treatment planning for ion beams
Biological planning optimization
Protons
Immobilisation techniques, necessity of a
particle gantry
19.00
Social event
R. Sweeney (Innsbruck)
Concert and reception at
Heidelberg Castle, free
evening at the old town of
Heidelberg
Saturday, September 29th, 2007
Morning session
9.00 - 9.30
9.30 - 10.00
10.30 - 11.00
11.00 - 11.30
11.30 - 12.00
12.00 - 12.30
Afternoon session
14.00 - 15.00
15.30 - 17.00
Round table
17.00
Closing speech
Clinical results of
particle therapy
S. Rossi (CNAO)*
T. DeLaney (MGH
Boston) (to be
confirmed)*
10.00 – 10.30 coffee
E. Hug (PSI)*
H. Tsujii (NIRS,
Japan)*
D. Schulz-Ertner
(Heidelberg)*
announcement
12.30 – 14.00 lunch
Status reports
S. Rossi (CNAO)
Q. Li (IMP, China)
U. Weber (RKA)
T. Auberger
(Innsbruck,MedAustron)
M. Bajard (Ètoile)
R. Kampf (Uni Kiel)
15.00 – 15.30 coffee
P. Pommier (Lyon)
J. DeLaney (MGH
Boston) (to be
confirmed)
T. Auberger (Innsbruck)
D. Schulz-Ertner
(Heidelberg)
K.P. Thiele (KC
Onkologie Düsseldorf)
J. Debus
Chairmen: D. Schulz-Ertner, Q. Li
Hospital-based therapy units for particle
therapy
Clinical results of proton RT in the USA
(MGH, Loma Linda)
Clinical results of proton RT in Europe
(PSI)
Clinical results of carbon ion RT in Japan
Clinical results of carbon ion RT at GSI
Chairmen: J. Debus, E. Hug (PSI)
Pavia
Lan Zhou
Marburg
Wiener Neustadt
Lyon
Kiel
Clinical indications for particle therapy, cost
effectiveness of particle therapy