B70 Animal Genetics Name ____________________________________ Date __________ Introduction No two animals are exactly alike. Even with twins one may be taller, one may be heavier, or grow faster. What two main factors contribute to these differences in animals? 1. 2. Phenotype Define phenotype: Define genotype: Both the _________________________ and the ____________________________ affect the physical appearance of the animal. Environmental Factors The quantity and quality of the ______________ ________________ conditions Exposure to ___________________ and ________________________ The type of _______________________ How much influence does a livestock producer have over the animal’s environment? How much influence does he have in the genetic make up of the animal? Explain how the above information would influence the kinds of livestock management practices that are going to have the greatest impact on the profitability of the operation? Natural Selection Explain natural selection: Controlled breeding A producer crosses two parents based on a desired outcome. A tough, dominant, alpha male may not be a desirable trait for domestic animals. Agriculture producers select for traits that have ____________________ importance. List four traits of economic importance 1. 3. 2. 4. The economically important traits are influenced by both the environment and the genetic make up of the animal. Controlled Breeding Programs ______________________: Breeding purebred animals with unrelated purebred animals. ______________________: Breeding animals of the same species but of a different breed. Hybrid Vigor or Heterosis A biological phenomenon which causes crossbreeds to _______________________ the average of their parents This will achieve _______________ % immediate increase in yield. The more __________________________ the breeds, the greater the heterosis: (British breed crossed with Zebu breed) Two-Breed Cross Purebred bulls X purebred cows of another breed Angus X Hereford = ___________________________ __________ % increase in weaning weight Two-Breed Backcross or Crisscross Breed A X Breed B = Crossbred calves Crossbred X Breed A or B Charolais Bull X Hereford Cow = Cross Cross X Charolais Yields _______ % of maximum heterosis Three Breed Rotation Cross 3 Breeds (Angus, Simmental, Charolais) Crossbred females bred to purebred bull of breed A Resulting cross mated to purebred bull of breed B Resulting cross mated to purebred bull of breed C Repeat rotation _______ % of maximum heterosis Gene Transfer All selection is based on the concept that desired characteristics are passed on from the parents to the offspring. Humans have _______ chromosomes. Each parent contributes ________. Define Chromosome: Define DNA: Each gene is responsible for a particular trait. Genes form a code or a blueprint for how the animal is to be formed. One chromosome (strand of DNA) will attach to another forming a spiral shape called a ______________________________ Each half is bound together by substances called ________________________. List the four main nucleotides. 1. 3. 2. 4. Nucleotides are shaped so that each substance can pair with one particular nucleotide. Adenine can only pair with _____________________ Cytosine can only pair with _____________________. When cells undergo _____________________ and divide, each half replicates itself so two strands exactly alike are formed. (DNA replication) The genetic sequence on the DNA is used as a pattern for how the animal is to be constructed. ________________________ reads the pattern and transfers the information the rest of the cell. Genetic Engineering Genetic engineering is a technology that allows specific genetic information or traits to be built into or engineered into the genes of a species. In genetic engineering, segments of DNA are ___________ and ________________ into existing DNA placing new genetic information into the existing DNA. Differentiation As the embryo begins to grow and develop, cells differentiate. Some cells develop into ___________________ and ________________, some into ____________ and some into ______________________________. The process of how cells differentiate is not fully understood. Sex cells called __________________________ undergo _________________ and only carry one strand of DNA. At conception, chromosome halves from each parent combine to form a paired chromosome. There is almost an infinite number of ways that the genes can be arranged on a strand of DNA. This arrangement determines the make up of the new animal. Alleles Each male gene that controls a specific trait combines with the female gene for the same trait. A pair of genes that control a specific trait are called ______________________. If both genes that control a specific trait are alike, they are said to be ___________________. For example: if the male gene for hair color is black and the female gene that controls hair color is also black. Gene Dominance If they are different (black & red) they are said to be _________________________. In this case one gene will be ___________________________, and determine coat color. Dominant Gene = trait overpowers others How are recessive genes expressed? ____________________________________ Gene Dominance P = _____________ p = _____________ Define genotype: Define phenotype: Punnett Squares 1. A homozygous horned cow (pp) is mated to a homozygous polled bull (PP), What is the genotypic result of this cross? ________________ What is the phenotypical result of this cross? _______________ 2. If a homozygous horned cow (pp) is bred with a heterozygous polled bull (Pp), What is the Genotypic result of this cross? ________________ What is the phenotypical result of this cross? _______________ 3. If two heterozygous polled animals are mated. What is the genotypic result of this cross? ________________ What is the phenotypical result of this cross? _______________ Define a monohybrid cross: Define a dihybrid cross: 4. If an Angus bull that is homozygous black and polled (BBPP) is mated to a red shorthorn cow that is homozygous red and horned (bbpp). BBPP can be simplified to BP (Black & Polled) bbpp can be simplified to bp (RED & Horned) What is the genotypic result of this cross? ________________ What is the phenotypical result of this cross? _______________ 5. If two of the offspring which are heterozygous for black/red and polled/horned (BbPp) are mated. How do you do a Punnett square for two heterozyous animals? Use all possible gene combinations Both the bull and cow are BbPp. What are the possible contributions? BP, Bp, bP,bp for both animals. (4 x 4 grid) What is the genotypic result of this cross? What is the phenotypical result of this cross? Black Polled = Black Horned = Red Polled = Red Horned = 6. When a heterozygous bull (BbPp) is mated to a homozygous cow (BBPP) What are the outcomes? 7. If a (BbPp) bull is mated to a (BBPp) cow. What are the outcomes? Mendilin Genetics 8. Paint color is desirable characteristic of paint horses and is dominate to solid color. If a homozygous dominant stallion is bred with a solid colored mare, how likely is it that a paint foal would result? 9. What if the stallion is heterozygous for paint color, how likely is it that I will get a paint foal? Codominate Genes Some alleles may have _____________ dominate genes. Shorthorn cattle are ___________, ______________, and _______________ Red shorthorns carry the gene for red coat color RR White shorthorns carry the gene for white coat color WW Cattle that are roan or spotted carry a gene for red and a gene for white RW Both are dominant, creating a spotted or roan colored animal. The Additive Expression of Genes Instead of a single pair a number of genes may be added together to produce a single trait. Examples: _______________ production is controlled by several genes. Size and ________________________ of the female __________________ production __________________ size and function Rate of _____________________ ___________________________ Genetic Mutations Occasionally a defect will happen and genetic traits are not passed on as intended. Example: two headed calves. Explain the difference between an abnormality and a genetic mutation? Sometimes genetic mutations can be used to introduce new kinds of species. _____________________________________ Determining an Animal’s Sex. Whether a mammal is a male or a female is determined upon _________________. _____________________ (sex cell) contains ___________ of the sex chromosome from the parent. The female chromosome is referred to as _________. When the chromosome divides and half goes to the offspring each half is the same. The male chromosome is referred to as _______. When divided, a gamete will be either X or Y. When the male and female gametes combine they will either be XX Female or XY male. What is the probability of a male child being conceived over a female?