Join us for a Southeast Regional Educational Meeting by conference call! GUEST SPEAKER John J. Bissler MD (Pediatric Nephrologist / Kidney Specialist) TOPIC Dr. Bissler addresses recent discoveries made in research, what that means to individuals living with TSC and how it translates into clinical trials. WHEN? Tuesday, March 31, 2009 7:00 p.m. CST 8:00 p.m. EST WHERE? Please dial 1-866-613-5223 Enter the pass code 9083528 followed by the # sign Please RSVP to Amy Hobbs by March 1, 2009 Phone: (615)665-3397 or E-mail: amyghobbs@aol.com Please RSVP by sending in any questions you may have for Dr. Bissler to Amy. She will compile a list of all questions and we will be forwarding those to Dr Bissler so he may customize his presentation. This will enable us to address as many questions as possible without taking up valuable phone time with a larger crowd. When you have reserved your spot, you will receive a copy of the presentation in late March. John J. Bissler MD Clark D. West Chair of Nephrology Director Nephrology Fellowship Training Program Associate Program Director for Research and Academic Careers John J. Bissler, M.D. is a graduate (AOA) of the Northeastern Ohio Universities College of Medicine after he earned his B.S. degree (Phi Bata Kappa, Magna Cum Laude) at Kent State University. After a three-year pediatric residency and chief residency at Akron Children’s Hospital, Dr. Bissler came to Cincinnati Children’s in 1988 for a fellowship in nephrology and in basic science. In 1991, he was awarded a William Cooper Procter pediatric research scholarship for two years. Now in his 18th year in the Division of Nephrology and Hypertension, he is an Associate Professor of Pediatrics and of Cell Biology as well as a clinical attending physician. In 2004, Dr. Bissler became the first recipient of the Clark D. West Endowed Chair of Pediatric Nephrology. Dr. Bissler treats patients with polycystic kidney disease and renal angiomyolipomas. After the brain, the kidney is the organ next most affected by TSC. Dr. Bissler is one of only two nephrologists worldwide with expertise in managing TSC-related kidney disease. His research has focused on alternative dialysis means, the treatment of renal angiomyolipomas, and on the recombinogenic sequences in the PKD1 and TSC2 genes. His research grants have come from the NIH as well as from the LAM Foundation and from the Tuberous Sclerosis Alliance. Dr. Bissler has had 11 U.S. patents and ten foreign country patents licensed. He is a member of the Scientific Advisory Board for grant review of the LAM Foundation and of the Tuberous Sclerosis Alliance. He is a member of the Editorial Board of Pediatric Nephrology and a member of the Medical Advisory Board of the Kidney Foundation of Greater Cincinnati. Dr. Bissler is the Director of the Pediatric Nephrology Fellowship Training Program in the Division of Nephrology and Hypertension as well as the Associate Program Director for Research and Academic Careers. Dr. Bissler practices at the Children's Hospital Medical Center Tuberous Sclerosis Complex Clinic in Cincinnati, Ohio. This clinic has more than 400 patients, making it one of the largest TSC clinics in the world. Dr. Bissler cares for the renal component of this disease process. Furthermore, in conjunction with Dr. David Franz, Director of the Tuberous Sclerosis Clinic, and Dr. Frank McCormack, Pulmonologist who specializes in the lymphangioleiomyomatosis, Dr. Bissler is conducting a clinical trial in hopes to discover a pharmacological treatment for the renal lesions of TSC.