BIOGRAPHICAL SKETCH
Provide the following information for the key personnel and other significant contributors.
Follow this format for each person. DO NOT EXCEED FOUR PAGES.
NAME
POSITION TITLE
David Roger Quilici
Director of the Nevada Proteomics Center
eRA COMMONS USER NAME
quilici
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION
University of Nevada
University of Nevada
DEGREE
(if applicable)
YEAR(s)
B.S.
Ph.D.
1990
1997
FIELD OF STUDY
Biochemistry
Biochemistry
A. Personal Statement
The goal as Director of the Nevada Proteomics Center is to provide high quality proteomic analysis to the
Nevada System of Higher Education. The facility is partially funded by an NIH-INBRE grant which also allows
for providing this high quality service to other INBRE funded states.
B. Positions and Honors.
Positions and Employment
1996-2006 Mass Spec. Manager, University of Nevada
2006-present Director of Proteomics, University of Nevada
Other Experience and Professional Memberships
1996-present Member, American Society for Mass Spectrometry
2007-present Member, Association of Biomolecular Resource Facilities
C. Selected Peer-reviewed Publications
Most relevant to the current application
Ulrich C, Quilici DR, Schegg K, Woolsey RJ, Nordmeier A, Buxton IL. (2012) Uterine Smooth Muscle SNitrosylproteome in Pregnancy. Mol Pharm 81(2):143-153. Doi:10.1124/mol.111.075804
Chang IF, Curran A, Woolsey R, Quilici D, Cushman JC, Mittler R, Harmon A, Harper JF (2009) Proteomic
Profiling of Tandem Affinity Purified 14-3-3 Protein Complexes in Arabidopsis thaliana Proteomics
9(11):2967-85
Deluc LG, Quilici DR, Decendit A, Grimplet J, Wheatley MD, Schlauch KA, Mérillon JM, Cushman JC, Cramer
GR. (2009) Water deficit alters differentially metabolic pathways affecting important flavor and quality traits
in grape berries of Cabernet Sauvignon and Chardonnay. BMC Genomics. May 8;10:212.
Hull JJ, Copley KS, Schegg KM, Quilici DR, Schooley DA, Welch WH. (2009) De novo molecular and
biophysical characterization of Manduca sexta eclosion hormone. Biochemistry Sep 29;48(38):9047-60.
Deluc LG, Grimplet J, Wheatley MD, Tillett RL, Quilici DR, Osborn C., Schooley DA, Schlauch KA, Wheatley
M, Cushman JC, Cramer GR. (2007) Transcriptomic and metabolomic analyses of Cabernet Sauvignon
grape berry development. BMC Genomics. 8:429.
Vincent D, Ergul A, Bohlman MC, Tattersall EA, Tillett R, Woosley R, Quilici DR, Joets J, Schlauch KA,
Schooley DA, Cushman JC, Cramer GR (2007) Proteomic analysis reveals differences between Vitis
vinifera L. cv. Chardonnay and Cabernet Sauvignon and their responses to water-deficit and salinity. J.
Exp. Botany. 58:1873-1892.
Rodriquez Milla, M.A., I-F. Chang, J. Townsend, E.A. Maher, D. Quilici, and J.C. Cushman. “A novel yeast
two-hybrid approach to identify CDPK substrates: Characterization of the interaction between AtCPK11
and AtDi19, a nuclear zinc finger protein1.” FEBS Letters 580, 904-911(2006).
Cramer G.R., J.C. Cushman, D.A. Schooley, D. Quilici, D. Vincent, C. Bohlman, A. Ergul, E.A. Tattersall, R.
Tillett, J. Evans, R. Delacruz, K. Schlauch, P. Mendes. Progress in bioinformatics – the challenge of
integrating transcriptomic, proteomic and metabolomic information. Acta Hort. 689: 417-425 (2005).
Hancock R., K. Schegg, D. Quilici, D.A. Schooley, R.S. Pardini. “Proteome Analysis of Omega-3 Fatty Acid
Treated Human Ovarian Carcinoma Using 2 D-electrophoresis and MALDI TOF/TOF Mass
Spectrometry,” Proc. Am. Assoc. Cancer Res. 45 (#3914) (2004).
Cramer, GR, Ergul, A, Vincent, D, Bohlman, C, Grimplet, J, Tattersall, EAR, Tillett, R, Evans, J, Quilici, D,
Schooley, D, Cushman, J, Schlauch, K, and Mendes, P. Integrative functional genomics of abioticallystressed grapevine: a system for discovery of gene and plant functions. 2006.
C. Research Support
Ongoing Research Support
P20 RR-016464
Kenyon PI 9/1/10-5/31/15
IDEA Network of Biomedical Research Excellence
The objective of this project is to promote multi-institutional cooperation and facilitate successful scientific
research by promising junior faculty, with an emphasis on research infrastructure. Quilici is in charge of the
mass spec lab in the Nevada Proteomics Center. The five year budget in support of this center is shown above
(direct costs only).
Completed Research Support
1S10RR23587-01A2
Quilici PI 7/1/09-6/31/10
IDEA Network of Biomedical Research Excellence
The objective of this project is to enhance the Nevada Proteomics Center’s LC-MS capabilities to meet the
current need in post translational site mapping. The Center has purchased a Thermo LTQ Orbitrap XL with
ETD.
5P20RR16464-5
Weber PI 7/1/05-5/31/10
IDEA Network of Biomedical Research Excellence
The objective of this project is to promote multi-institutional cooperation and facilitate successful scientific
research by promising junior faculty, with an emphasis on research infrastructure. Quilici is in charge of the
mass spec lab in the Nevada Proteomics Center. The five year budget in support of this center is shown above
(direct costs only).