Clinical Pharmacology
Teachers:
dr hab. n. med. Grzegorz Grześk
prof. dr hab. n. med. Leszek Szadujkis-Szadurski
dr n. med. Tomasz Kornatowski
dr n. med. Marek Krzyżanowski
dr n. med. Anna Witkowska
dr n. med. Ahmad Sinjab Thabit
dr n. med. Katarzyna Szadujkis-Szadurska
dr Rafał Szadujkis-Szadurski
dr n. med. Michał Wiciński
lek. Grzegorz Matusiak
Contact: kizfarmak@cm.umk.pl
Syllabus
I. Chair and Department of Pharmacology and Pharmacological Therapy
II. Head of the Department: dr hab. n. med. Grzegorz Grześk
III. Faculty of Medicine, sixth year
IV. Programme Tutor: dr hab. n. med. Grzegorz Grześk
V. Seminars, tutorials
VI. Assessment: credit with grade, 2 ECTS points
VII. Subject Hours: seminars 15h, tutorials 15h
VIII. Aims of the subject:
1) Understanding the mechanism and effects of drugs with particular emphasis on
therapeutic activities, adverse reaction (side effects), toxicity, teratogenic,
embiotoxic and carcinogenic effects;
2) Assimilating the principles of clinical procedures in cardiovascular disease,
urinary system, alimentary system, hematopoietic system and evaluation of drug
action, analysis of the risks and benefits. Understanding the paths of drug
dosing, pharmacokinetic basics and principles of drug dosing;
3) Reasonable chemioteraphy, the use of antibiotics, antimycoctic and antivirus
drugs
4) Placental transfer of drugs;
5) Objective clinical methods for drug acting efficiency on humans with particular
emphasis on risks and benefits evaluation;.
6) Pharmacokinetic and pharmacodynamical interactions.
IX.Topics of lectures/ tutorials/ seminars
Seminars and tutorials:
1) Clinical Pharmacology of drugs acting on cardiovascular system:

Pharmacotherapy of coronary disease;

Pharmacotherapy of coronary attack

Drugs used in pharmacotherapy of heart failure;

Treatment of hypertension- clinical examples;

Reasonable therapy of heart muscle insufficiency.
2) Arteriosclerosis and metabolizm of lipoproteins. Lipid- lowering drugs:

Clinical basics of hyperlipidemics treatment.
3) Homeostasis and thrombosis- clinical examples.
4). Pharmacokinetic of respiratory system- clinical examples:

Bronchial asthma- clinical examples;

COPD (chronic obstructive lung disease);

Acute spastic states.
5). Pharmacotherapy of urial system:

Urolithiasis- clinical examples;

Urinary tract infection therapeutic treatment;

Acute and chronic renal failure- clinical examples.
6). Pharmacotherpay of digestive system:

Duodenal ulcer- clinical examples;

Reflux disease- methods of treatment;

Pancreatitis (acute, chronic) - clinical examples;

Hepatisis.
7). Disease of endosecretory glands:

Diabetes mellitus;

Thyroid’s and parathyroid failures- clinical examples;

Hypothalamus and Hypophysys failures;

Adrenal diseases.
8). Osteoporosis.
9). Menopause.
10). Andropause – hormonal- replacement therapy.
11). Drugs interactions:

Pharmacokinetic;

Pharmacodnamical- clinical examples.
X. Self study topics.
XI. Booklist:
XII. Detailed list of required practical skills and confirmation of completing
STUDENT COMPETENCY CARD
COURSE SYLLABUS: CLINICAL PHARMACOLOGY
MEDICAL FACULTY – 6TH YEAR OF STUDY
Students name/surname: .........................................................................................................
Practical assessment
Using the evaluation methods of
pharmacological drug action
including toxicity evaluation, side
effects, mechanisms of action and
the point of the handle.
Solving pharmacotherapeutic
problems in selected patients.
Date of pass
Instructor’s
Confirmation
Remarks
Rules and regulations