Beavers, Kristen Marie BIOGRAPHICAL SKETCH Provide the following information for the key personnel and other significant contributors in the order listed on Form Page 2. Follow this format for each person. DO NOT EXCEED FOUR PAGES. NAME POSITION TITLE Beavers, Kristen M. eRA COMMONS USER NAME (credential, e.g., agency login) Visiting Assistant Professor kbeavers EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) INSTITUTION AND LOCATION Cornell University, Ithaca, NY University of North Carolina, Chapel Hill, NC Baylor University, Waco, TX Wake Forest University, Winston-Salem, NC DEGREE (if applicable) YEAR(s) BS MPH, RD PhD Postdoc 2004 2006 2009 2012 FIELD OF STUDY Human Biology Nutrition Exercise & Nutrition Gerontology A. Positions and Honors. List in chronological order previous positions, concluding with your present position. List any honors. Include present membership on any Federal Government public advisory committee. Positions: 2004-2006 2006-2009 2007-2009 2009-2012 2012-Present Research Assistant, Department of Nutrition, UNC - Chapel Hill NC Research Assistant, Exercise, Sport, and Nutrition Laboratory, Baylor University, Waco TX Teacher of Record: Introduction to Nutrition, Baylor University, Waco TX Postdoctoral Research Fellow, Wake Forest School of Medicine, Winston-Salem NC Visiting Assistant Professor, Department of Health and Exercise Science, Wake Forest University, Winston-Salem NC B. Selected peer-reviewed publications (in chronological order; 15 of 18). 1. Gordon-Larsen P, Nelson MC, Beam K. Associations among active transportation, physical activity, and weight status in young adults. Obesity Research. 2005; 13(5):868-75. 2. Beavers KM, Beavers DP, Serra MC, Bowden RG, Wilson RL. Low Relative Skeletal Muscle Mass Indicative of Sarcopenia is Associated with Elevations in serum Uric Acid Levels: Findings from NHANES III. Journal of Nutrition, Health, and Aging. 2009; 13(3):177-182. 3. Beavers KM, Jonnalagadda SS, Messina MJ. Soy consumption, adhesion molecules, and proinflammatory cytokines: a brief review of the literature. Nutrition Reviews. 2009; 67(4):213-21. 4. Beavers KM, Beavers DP, Bowden RG, Gentile M, Wilson RL. The Effect of OTC Fish Oil Administration on Plasma Lp(a) Levels in an End Stage Renal Disease Population. Journal of Renal Nutrition. 2009; 19(6):443–449. 5. Beavers KM, Serra MC, Beavers DP, Cooke MB, Willoughby DS. Soymilk supplementation does not alter plasma markers of inflammation and oxidative stress in postmenopausal women. Nutrition Research. 2009; 29(9):616-22. 6. Beavers KM, Brinkley TE, Nicklas BJ. Effect of exercise on chronic inflammation. Clinica Chimica Acta 2010; 411(11-12):785-93. PHS 398/2590 (Rev. 11/07) Page 1 Biographical Sketch Format Page Beavers, Kristen Marie 7. Beavers KM, Serra MC, Beavers DP, Hudson GM, Willoughby DS. The lipid lowering effects of four weeks of daily soymilk or dairy milk ingestion in a postmenopausal female population. Journal of Medicinal Food. 2010; 13(3):650-656. 8. Beavers KM, Serra MC, Beavers DP, Cooke MB, Willoughby DS. Soy and the Exercise Induced Inflammatory Response in Postmenopausal Women. Applied Physiology, Nutrition, and Metabolism. 2010; 35(3):261–269. 9. Nicklas BJ, Beavers KM. Exercise, Weight Loss, and Effects on Inflammation. Current Cardiovascular Risk Reports. 2010; 4(4):284-292. 10. Beavers KM, Hsu FC, Isom S, Kritchevsky SB, Church T, Goodpaster B, Pahor M, Nicklas BJ. Longterm physical activity and inflammatory biomarkers in older adults. Med Sci Sports Exerc. 2010; 42(12):2189-96. 11. Beavers DP, Beavers KM, Miller M, Stamey J, Messina MJ. Exposure to Isoflavone-Containing Soy Products and Endothelial Function: A Bayesian Meta-Analysis of Randomized Controlled Trials. Nutr Metab Cardiovasc Dis. 2010 Aug 14. [Epub ahead of print] 12. Beavers KM and Nicklas BJ. Effects of lifestyle interventions on inflammatory markers in the metabolic syndrome. Front Biosci (Schol Ed). 2011; 3:168-177. 13. Kreider RB, Serra MC, Beavers KM, Moreillon J, Kresta JY, Byrd M, Oliver JM, Jitomir-Gutierrez J, Hudson G, Deike E, Shelmadine B, Leeke P, Rasmussen C, Greenwood M, Cooke M, Kerksick C, Campbell JK, Beiseigel J, Jonnalagadda SS. A structured diet and exercise program promotes favorable changes in weight loss, body composition, and weight maintenance. J Am Diet Assoc. 2011; 111(6):828-43. 14. Beavers KM, Lyles MF, Davis CC, Wang X, Nicklas BJ. Is lost lean mass from intentional weight loss recovered during weight regain in postmenopausal women? Am J Clin Nutr. 2011; 94(3):767-74. 15. Beavers KM, Miller ME, Rejeski WJ, Nicklas BJ, Kritchevsky SB. Fat mass loss predicts gain in physical function with intentional weight loss in older adults. Accepted to the Journal of Gerontology: Medical Sciences. C. Research Support. Current and Pending: K99 AG044478 (PI: Beavers) Submitted 6/12/12 NIH/NIA “Clinical Effects of Dietary Protein Source during Weight Loss in Older Adults.” This study is designed to determine whether a soy-based weight loss program is more effective at reducing ectopic fat stores and associated cardio-metabolic impairments, while preserving lean mass, than a nonsoy control. Additionally, grant support will allow Dr. Beavers the opportunity to gain additional training in microarray and CT image analysis. Pepper Pilot Grant (PI: Beavers) 7/1/11-12/31/12 OAIC “Use of a Soy-based Meal Replacement Weight Loss Intervention to Impact Ectopic Fat and Associated Cardio-metabolic Risk in Obese, Older Adults: A Feasibility Study”. This study is designed to determine whether a soy-based weight loss program is more effective at reducing ectopic fat stores and associated cardio-metabolic and functional impairments than a non-soy control. Because this is a pilot study, the primary endpoints for this study are measures of feasibility – accrual, retention, and compliance. Support provided by the Older Americans Independence Center has been leveraged with PHS 398/2590 (Rev. 11/07) Page 2 Continuation Format Page Beavers, Kristen Marie support committed by the Wake Forest School of Medicine Clinical Research Unit, Center for Integrative Medicine, Translational Science Institute, Translational Science Center, and Jason Pharmaceuticals, Inc. Role: Principle Investigator Past: F32 AG039186 (PI: Beavers) 1/1/11-6/30/12 NIH/NIA “The role of metabolic syndrome and inflammation on physical function in the elderly.” This study will examined whether the relationship between metabolic syndrome and physical dysfunction is mediated by inflammation in older adults in the Health ABC cohort. Role: Principle Investigator CRU Pilot Study Grant 1/1/09-6/30/10 WFU CRC “The Relationship Between Serum Uric Acid and Physical Function in Older Adults At Risk for Disability.” This study is an ancillary study to the on-going Lifestyle Interventions and Independence for Elders (LIFE) study, a 4-site, randomized, controlled trial in 424 elderly men and women at risk for physical disability. The primary hypothesis is that elevations in baseline serum uric acid will be inversely related to measures of physical function (walking speed and muscle strength) and lean body mass (DEXA measurements). Role: Co-Principle Investigator R01 HL093713 (PI: Nicklas) 7/1/09-6/30/14 NIH/NHLBI “Effect of fat loss on functional and cardiovascular benefits of aerobic exercise” This study will determine whether older, obese men and women who lose more fat during an exercise training program will experience greater improvements in aerobic function as a result of the exercise training. Role: Co-Investigator R01 AG027529 (PI: Nicklas) 9/15/06-8/31/10 NIH/NIA “Exercise training and inflammatory risk factors for disability.” This study is an ancillary study to the on-going Lifestyle Interventions and Independence for Elders (LIFE) study, a 4-site, randomized, controlled trial in 424 elderly men and women at risk for physical disability. The primary hypothesis is: compared to a non-exercise health education intervention, a 12-month exercise training intervention will decrease con-centrations of inflammatory biomarkers in elderly men and women. Role: Co-Investigator PHS 398/2590 (Rev. 11/07) Page 2 Continuation Format Page