Table of graduate student supervisor
Name
Ji Min
Professional titles
Professor
Doctoral
supervisor Doctoral supervisor
OR
Master's
supervisor
Major
Nano medicine, Medicinal Chemistry
Academic
expertise 1. Design, synthesis and application
and research direction
pharmaceutical nano-material
of
novel
2. Anti-tumor activity of multi-targets kinase inhibitors
3. Design and synthesis of central nerves system (CNS)
drugs
4. Research of Drug delivery system
Current research and  July, 2011 – July, 2014
other projects
“Technology development
and
industrialization
of
enzyme catalyzed synthesis of high quality atorvastatin
calcium and its intermediates”, Major Achievements
Transfer Projects of Jiangsu province (BA2011130), the
team leader.
 July, 2011 – July, 2014
“Continuous chromatographic separation technique for
preparation
of
high
purity
Netilmicin”,
Major
Achievements Transfer Projects of Jiangsu province
(BA2011035), the team leader.
 July, 2012 – July, 2014
“Green technology and industrialization of atorvastatin
calcium preparation”, The prospective project of Jiangsu
Province (BY2012203), the team leader.
 July, 2009 – July, 2012
“Multiple targets kinase inhibitors Segitinib for antitumor
preclinical studies”, Social Development---Technology
Supporting Program of Jiangsu province (BE2009639),
Books and papers
the team leader.
Books:
1.《Combinatory Chemistry》Chemical series of books in the
21st century Chemical Industry press 2004.6. Jimin
Write
2．《Medicinal Chemistry》（Ordinary higher education " 15
" teaching materials of national-level planning "）Higher
Education Press 2004.11. Jimin join writing
3．
《Medicinal Chemistry》The guide for entrance of National
operation pharmacist's qualifying examination Chinese
Pharmaceutical Scientific and technological publishing
house 1997,2001 Jimin join writing
Papers:
1. Zhang, S. G.; Feng, C. L.; Cai, J.; Chen, J. Q.; Hu, H. Y.; Ji, M.
Solvent free synthesis of 2-acylpyrroles and its derivatives catalysed
by reuseable zinc oxide. Journal of Chemical Research 2013,
480-482.
2. Zheng, Y. G.; Zheng, M.; Ling, X.; Liu, Y.; Xue, Y. S.; An, L.;
Gu, N.; Ji, M. Design, synthesis, quantum chemical studies and
biological activity evaluation of pyrazole-benzimidazole derivatives
as potent Aurora A/B kinase inhibitors (vol 23, pg 3523, 2013).
Bioorganic & Medicinal Chemistry Letters 2013, 23, 4471-4471.
3. Feng, C. L.; Zhang, S. G.; Chen, J. Q.; Cai, J.; Ji, M. First total
synthesis of isoquinolinone alkaloid marinamide and its methyl ester.
Chinese Chemical Letters 2013, 24, 767-769.
4. Zhang, S. G.; Huang, S.; Feng, C. L.; Cai, J.; Chen, J. Q.; Ji, M.
Novel preparation of tiaprofenic acid. Journal of Chemical Research
2013, 406-408.
5. Zheng, M.; Zheng, Y. G.; Xie, L.; Chang, W. W.; Gu, N.; Ji, M.
Orally Active Aurora A/B Kinase Inhibitor, AM-005, Suppresses the
Growth of Human Colon Carcinoma Cells. Drug Development
Research 2013, 74, 272-281.
6. Zheng, Y. G.; Zheng, M.; Liu, Y.; Xue, Y. S.; Zhang, L.; An, L.;
Liu, L.; Ji, M. Design, Synthesis, and In vitro Antitumor Evaluation
of Novel Phenylaminopyrimidine Derivatives. Medicinal Chemistry
2013, 9, 340-350.
7. Cai, J.; Sun, M.; Wu, X. Q.; Chen, J. Q.; Wang, P.; Zong, X.; Ji,
M. Design and synthesis of novel 4-benzothiazole amino
quinazolines Dasatinib derivatives as potential anti-tumor agents.
European Journal Of Medicinal Chemistry 2013, 63, 702-712.
8. Zhang, S. G.; Feng, C. L.; Cai, J.; Chen, J. Q.; Ji, M. Total
synthesis of a novel isoquinolinone alkaloid marinamide and its
methyl ester. Journal of Chemical Research 2013, 291-293.
9. Zheng, M.; Zheng, Y. G.; Xue, Y. S.; Liu, Y.; An, L.; Zhang, L.;
Ji, M.; Xue, B.; Wu, X.; Gong, X. D.; Gu, N.; Zhan, X. Synthesis and
Quantum Chemical Studies of New 4-aminoquinazoline Derivatives
as Aurora A/B Kinase Inhibitors. Chemical Biology & Drug Design
2013, 81, 399-407.
10. Wang, P.; Cai, J.; Yang, J. B.; Sun, C. L.; Li, L. S.; Ji, M.
Solvent-Dependent Regioselective Oxidation of trans-Chalcones
using Aqueous Hydrogen Peroxide. Journal Of The Brazilian
Chemical Society 2013, 24, 518-522.
11. Wang, P.; Cai, J.; Yang, J. B.; Sun, C. L.; Li, L. S.; Hu, H. Y.; Ji,
M. Zinc(II)-catalyzed oxidation of alcohols to carbonyl compounds
with chloramine-T. Tetrahedron Letters 2013, 54, 533-535.
12. Duan, Y. B.; Ji, M.; Lu, X. H. Simultaneous high-performance
liquid chromatographic determination of a rhein-diclofenac prodrug
and its active compounds. Pharmazie 2013, 68, 12-14.
13. Wang, P.; Yang, J. B.; Cai, J.; Sun, C. L.; Li, L. S.; Ji, M. An
efficient and facile synthesis of flavanones catalyzed by
N-methylimidazole. Journal Of The Serbian Chemical Society 2013,
78, 917-920.
14. Cao, M.; Zhan, T. L.; Ji, M.; Zhan, X. Dimerization is necessary
for MIM-mediated membrane deformation and endocytosis.
Biochemical Journal 2012, 446, 469-475.
15. Cai, J.; Duan, Y. B.; Yu, J.; Chen, J. Q.; Chao, M.; Ji, M.
Bone-targeting glycol and NSAIDS ester prodrugs of rhein:
Synthesis, hydroxyapatite affinity, stability, anti-inflammatory,
ulcerogenicity index and pharmacokinetics studies. European Journal
Of Medicinal Chemistry 2012, 55, 409-419.
16. Hu, H. Y.; Liu, Y.; Zhong, H.; Zhu, Y. L.; Wang, C.; Ji, M.
Heck-Type Cross-Dehydrogenative Coupling Reactions of
Indolizines at the 3-Position with Electron-Deficient Alkenes through
Palladium-Catalyzed C?H Activation. Chemistry-an Asian Journal
2012, 7, 884-888.
17. Cai, J.; Zhang, S. N.; Zheng, M.; Wu, X. Q.; Chen, J. Q.; Ji, M.
Design, synthesis, and in vitro antiproliferative activity of novel
Dasatinib derivatives. Bioorganic & Medicinal Chemistry Letters
2012, 22, 806-810.
18. Wu, X. Q.; Li, M. D.; Tang, W. H.; Zheng, Y. G.; Lian, J. Q.; Xu,
L.; Ji, M. Design, Synthesis, and In vitro Antitumor Activity
Evaluation of Novel 4-pyrrylamino Quinazoline Derivatives.
Chemical Biology & Drug Design 2011, 78, 932-940.
19. Zheng, Y. G.; Sun, M.; Liu, Y.; Li, M. D.; Ji, M. Design,
Synthesis of Novel Quinazolone Alkaloids Derivatives as Potential
Antitumor Agents. Medicinal Chemistry 2011, 7, 295-300.
20. Chen, J. Q.; Sun, M.; Cai, J.; Cao, M.; Zhou, W.; Ji, M. The
Synthesis and Crystal Structure of (4 alpha,8 beta,13 beta,16
beta)-13-Methyl-16,18-diol-17-Norkaurane:
A
Simultaneous
Reduction Product of Isosteviol. Journal Of Chemical
Crystallography 2011, 41, 519-522.
21. Chen, J. Q.; Zha, X. M.; Sun, M.; Cai, J.; Zhou, W.; Ji, M.
Synthesis and In Vivo Acute Antihyperglycemic Evaluation of Novel
Isosteviol Derivatives. Letters in Drug Design & Discovery 2010, 7,
686-693.
22. Zheng, Y. G.; Wu, X. Q.; Xue, B.; Li, M. D.; Ji, M. Design,
Synthesis, Docking and Antitumor Activity of Quinazolino [3, 4-a]
thieno [3, 2-d] pyrimidin-8-one Derivatives. Chemical Biology &
Drug Design 2010, 76, 285-290.
23. Wu, X. Q.; Li, M. D.; Qu, Y.; Tang, W. H.; Zheng, Y. G.; Lian, J.
Q.; Ji, M.; Xu, L. Design and synthesis of novel Gefitinib analogues
with improved anti-tumor activity. Bioorganic & Medicinal
Chemistry 2010, 18, 3812-3822.
24. Sun, M.; Wu, X. Q.; Chen, J. Q.; Cai, J.; Cao, M.; Ji, M. Design,
synthesis, and in vitro antitumor evaluation of novel diaryl ureas
derivatives. European Journal Of Medicinal Chemistry 2010, 45,
2299-2306.
25. Sun, M.; Chen, J. Q.; Cai, J.; Cao, M.; Yin, S. Q.; Ji, M.
Simultaneously Optimized Support Vector Regression Combined
With Genetic Algorithm for QSAR Analysis of KDR/VEGFR-2
Inhibitors. Chemical Biology & Drug Design 2010, 75, 494-505.
26. Duan, Y. B.; Yu, J.; Liu, S.; Ji, M. Synthesis of
Anthraquinone-Ibuprofen Prodrugs with Hydroxyapatite Affinity and
Anti-Inflammatory Activity Characteristics. Medicinal Chemistry
2009, 5, 577-582.
27. Sun, M.; Zheng, Y. G.; Wei, H. T.; Chen, J. Q.; Ji, M. QSAR
studies on 4-anilino-3-quinolinecarbonitriles as Src kinase inhibitors
using robust PCA and both linear and nonlinear models. Journal Of
Enzyme Inhibition And Medicinal Chemistry 2009, 24, 1109-1116.
28. Zheng, Y. G.; Wu, X. Q.; Sun, M.; Feng, L. H.; Li, M. D.; Ji, M.
Design, Synthesis, Crystal Structure and Antitumor Activity of A New
Ethyl 3-(quinazolin-4-ylamino)-1H-pyrrole-2-carboxylate Derivative.
Letters in Drug Design & Discovery 2009, 6, 538-541.
29. Duan, Y. B.; Yu, J.; Liu, H. F.; Ji, M. Bone-Targeting
Anthraquinone-Diclofenac Prodrugs with Hydrolytic and Bone
Affinity Characteristics. Letters in Drug Design & Discovery 2009, 6,
393-396.
30. Sun, M.; Chen, J. Q.; Wei, H. T.; Yin, S. Q.; Yang, Y.; Ji, M.
Quantitative Structure-Activity Relationship and Classification
Analysis of Diaryl Ureas Against Vascular Endothelial Growth Factor
Receptor-2 Kinase Using Linear and Non-Linear Models. Chemical
Biology & Drug Design 2009, 73, 644-654.
31. Wei, H. T.; Sun, M.; Ji, M. A straightforward expeditious
synthesis of 5-nitrobenzo[b]thiophene-2-carbaldehyde. Journal Of
Chemical Research-s 2009, 359-360.
32. Zheng, Y. G.; Li, M. D.; Zhang, S. N.; Ji, M. Novel preparation
of gefitinib. Journal Of Chemical Research-s 2009, 388-390.
33. Sun, M.; Zheng, Y. G.; Wei, H. T.; Chen, J. Q.; Cai, J.; Ji, M.
Enhanced Replacement Method-based Quantitative Structure Activity Relationship Modeling and Support Vector Machine
Classification of 4-Anilino-3-quinolinecarbonitriles as Src Kinase
Inhibitors. Qsar & Combinatorial Science 2009, 28, 312-324.
34. Cai, J.; Zhou, W.; Chen, J. Q.; Sun, M.; Ji, M. Synthesis and
Crystal Structure of Benzoyloxymethyl (4 alpha,8 beta,13
beta)-13-methyl-16-oxo-17-norkauran-18-carbonate Ester. Journal Of
Chemical Crystallography 2009, 39, 108-111.
35. Liu, H. F.; Wu, X. Q.; Duan, Y. B.; Dou, R. B.; Sun, H. F.; Ji, M.
An efficient one-pot synthesis of cyclovirobuxine A from buxozine C.
Chemistry Of Natural Compounds 2008, 44, 829-830.
36. Shi, C. L.; Chen, H.; Li, Y.; Shi, D. Q.; Ji, M. A
three-component synthesis of N-substituted quinoline-3-carbonitrile
derivatives catalysed by L-proline. Journal Of Chemical Research-s
2008, 534-537.
37. Shi, C. L.; Shi, D. Q.; Kim, S. H.; Huang, Z. B.; Ji, S. J.; Ji, M.
A novel and efficient one-pot synthesis of furo[3 ',4 ':
5,6]pyrido[2,3-c]pyrazole
derivatives
using
organocatalysts.
Tetrahedron 2008, 64, 2425-2432.
38. Liu, H. F.; Wu, X. Q.; Duan, Y. B.; Gu, B.; Ji, M. An efficient
one-pot, two-step synthesis of cyclobuxophyllinine M from
cyclovirobuxine D in aqueous media. Letters In Organic Chemistry
2008, 5, 140-141.
39. Yang, F.; Gu, A. Y.; Chen, Z. P.; Gu, N.; Ji, M. Multiple
emulsion microbubbles for ultrasound imaging. Materials Letters
2008, 62, 121-124.
40. Sun, M.; Wei, H. T.; Li, D.; Zheng, Y. G.; Cai, J.; Ji, M. Mild and
efficient one-pot synthesis of 2-imidazolines from nitriles using
sodium hydrosulfide as catalyst. Synthetic Communications 2008, 38,
3151-3158.
41. Shi, C. L.; Shi, D. Q.; Kim, S. H.; Huang, Z. B.; Ji, M. A novel
and
efficient
synthesis
of
3,3
'-benzylidenebis(4-hydroxy-6-methylpyridin-2(1H)-one) derivatives
through a multi-component reaction catalyzed by L-proline.
Australian Journal Of Chemistry 2008, 61, 547-551.
42. Wei, H.; Cai, J.; Sun, M.; Ji, M. Synthesis of substituted
thieno[2,3-b]pyrroles. Heteroatom Chemistry 2007, 18, 236-238.
43. Liu, H. F.; Ji, M.; Cai, J. Short and efficient approach towards
buxozine-C, an alkaloid from Buxus sempervirens. Archiv Der
Pharmazie 2006, 339, 675-676.
Email
jimin@seu.edu.cn
Other explanation
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