Physical Growth and Development In Adolescents Warren M. Seigel M.D., F.A.A.P., F.S.A.M. Chairman, Department of Pediatrics Director of Adolescent Medicine Coney Island Hospital Brooklyn, NY Associate Professor of Clinical Pediatrics State University of New York at Brooklyn I. Normal Growth and Development A. Puberty – the physical changes associated with development 1. Major changes during puberty Maturation of primary sex organs and the appearance of secondary sexual characteristics (e.g. pubic hair, facial hair) Skeletal growth increases Body composition and distribution of fat becomes more adult like Strength and endurance increases 2. Features of Puberty Sequence of changes is similar for all adolescents Variations in tempo or timing are common among adolescents Physical changes reflect underlying hormonal change. II. Pubertal Development General Concept – sexual maturity rating (also known as Tanner Staging) – a shorthand notation used to describe stages of physical development A. Female 1. Typical sequence of events Thelarche – breast development Adrenarche – pubic hair development Pubarche – growth Menarche – appearance of menses B. Breast Development SMR-1: the typical preadolescent breast. Lacking breast tissue or significant development of the nipple or areola SMR-2: the breast and papilla become elevated and appear as a small mound. There is increased areolar diameter as well as the appearance of increased areolar pigmentation SMR-3: the breast and areola are enlarged but are continuous in contour, with separation of the nipple from the contour of the breast SMR-4: the breast and areola continue to increase in size and mass. There is separation of the areola and papilla of the nipple to form a separate mound of tissue SMR-5: the mature female breast. The nipple projects slightly but the areola is contiguous with the contour of the breast C. Pubic Hair SMR-1: preadolescent SMR-2: sparse, downy, straight pubic hair appears first at the medial border of the labia majora. SMR-3: darker, curly pubic hair, appears at the medical aspect of the labia majora and spreads upward and outward in a typical triangular distribution SMR-4: coarse, curly pubic hair becomes more abundant, but less than typical adult amount and distribution SMR-5: coarse, curly pubic hair, in typical adult female distribution with pubic hair present on the medial aspects of the thighs or coursing upwards along linea alba up toward the umbilicus D. III. Important Features of Adolescent Female Development 1. Average age of onset of puberty = 10 years (range 813). 2. Growth spurt (peak height velocity) occurs during SMR-2. 3. Average height achieved during growth spurt = 4-6 inches. 4. Rate of growth in females decreases immediately prior to the onset of menses. 5. Menarche (onset of menses) occurs during SMR-4 in the majority of females (May be delayed to SMR-5 occasionally). 6. Average age at menarche = 12 years (range 10-16) 7. At menarche, the majority of females have achieved 95% of their ultimate adult height. 8. Length of puberty = 4 years Pubertal development may be delayed by poor health, intense exercise, low body weight, poor nutrition, chronic illness. 9. Breast asymmetry is common in adolescent females and does not signify pathology. 10.Acne often accompanies pubertal development and may become severe during SMR stages 3 and 4. PUBERTAL DEVELOPMENT IN ADOLESCENT MALES A. Sequence of pubertal changes in males Enlargement of the testes Lengthening of penis Appearance of pubic hair Physical growth Sexual maturity rating (also known as Tanner stage) are utilized in the assessment of adequacy of males development B. Testicular development SMR-1: preadolescent testes SMR-2: testicles slightly enlarged, scrotal skin darkens in pigment, texture thins SMR-3: testicles increase in size and volume SMR-4: testicles increase in size, scrotal skin dark SMR-5: adult tests and scrotum C. Penis development SMR-1: preadolescent male SMR-2: darkening of site of circumcision (in circumcised males), slight increase in length SMR-3: enlargement of the glans penis and increase in length SMR-4: larger, glans and breadth increases in size SMR-5: adult penis D. Pubic hair development SMR-1: preadolescent; no pubic hair SMR-2: sparse, downy straight pubic hair located at the base of the pubic bone and base of the penis SMR-3: coarse, darker pubic hair initially located at the base of the penis and extending in an upward, outward direction SMR-4: darker, curly pubic hair increased in amount, in similar distribution to stage 3 but less amount than in the adult SMR-5: adult masculine pubic hair distribution to include pubic hair present at medial aspects of the thighs. May not hair coursing upwards alone linea alba toward the umbilicus E. Important features of male pubertal development Average age of onset of puberty = 12 years (range 9-13) Growth spurt (peak height velocity) occurs generally between SMR-3 and SMR-4 First ejaculation occur at SMR-3 F. Sperm production (spermarche) occurs at SMR-3 Average height gained during puberty = 5-7 inches Strength peak occurs between SMR-4 and SMR-5 Gynecomastia (swelling of breast tissue) very common among adolescent males; occurs in approximately 60% of boys between SMR-2 and SMR-4 Common concerns about puberty in adolescents Pubertal delay – often perceived delay by the adolescent, but within normal range Puberty beginning early – more common in females (may result in stress), but generally normal variation Partial puberty beginning early Premature thelarche – isolated breast development Premature adrenarche – isolated pubic hair development Neither premature adrenarche or thelarche indicate significant pathology or endocrine abnormality. Must be placed within the context of the patient and his/her history and physical examination. G. Other physical or laboratory findings associated with pubertal change in adolescents Serum alkaline phosphatase levels rise for both males and females during periods of rapid growth. Elevated levels will decrease following period of significant growth. Hemoglobin and hematocrit will increase under hormonal influence during period of growth. Increase will be sustained following pubertal change.