SHARED CARE GUIDELINES (SCG) September 2014 For any drug listed the status will be red if using for an unlicensed indication unless the indication is specifically mentioned below. Expired SCGs may be used at the discretion/risk of the responsible prescriber. Drugs marked ** differ from the GMMMG overarching RAG list. Drug (proprietary examples) Acamprosate Agomelatine** Indications & Rationale Expiry date Maintenance of alcohol abstinence Adults with major depressive disorder where therapy initiated before July 2011 when NICE gave a negative assessment Antibiotics – nebulised Colomycin®, Expired but drug is only to be used for preexisting patients September 2015 Guideline (if available) Red as no SCP provided to SCCG Pennine 3346 Agomelatine for the treatment of major d Colomycin SCP. Sep 13.pdf Promixin®, Antipsychotic injections (Schizophrenia) Tobramycin - Tobi® Podhaler Only for those patients under the care of a community psychiatric nurse. Apomorphine injection Parkinson’s disease Red as no SCP provided to SCCG Expired antipsychotics including LA injections Expired Apomorphine Oct2011.pdf Atomoxetine ADHD (Adults and children over 6) Specialist to initiate and only request SCP when patient is on a stable dose >3 months Expired Atomoxetine_in_child _and_adolescent_ADHD_May_2012.pdf Methylphenidate_an d_atomoxetine_in_Adult_ADHD_Version_ Atypical Antipsychotics (oral) Use in dementia patients. Specialist initiation and follow up required. In development Atypical antipsychotics (oral) except clozapine which is RED Licensed indications (including Aripiprazole) and unlicensed indications as recommended by NICE (i.e. psychotic depression or anxiety in bipolar disorder) Expired Red as no SCP approved by SCCG Antipsychotics SCP Pennine Azathioprine Autoimmune disease (licensed) or for maintenance therapy in inflammatory bowel diseases (unlicensed) or severe refractory eczema (unlicensed) or Rheumatoid Arthritis - April 2016 SCP Azathioprine and Mercaptopurine.v1 Apr 14.pdf No SCP Expired Azathioprine.pdf Ciclosporin Licensed indications Rheumatoid Arthritis Expired Ciclosporin in RA.pdf Cinacalcet Dalteparin Deferasirox Denosumab Other licensed indications Transplant rejection Atopic dermatitis or psoriasis Nephrotic syndrome NB Unlicensed use in ulcerative colitis is RED Primary hyperparathyroidism NB For secondary hyperparathyroidism the drug is RED See also Low Molecular weight heparins Christie SCP can be used by any Trust for Cancer patients Licensed indications only For osteoporosis in post menopausal women-Use 60mg/ml All other indications Red as no SCP provided to SCCG October 2016 Cinacalcet_Shared_C are_Protocol v2 Oct 14.pdf September 2014 Dalteparin for cancer patients- Christie Red as no SCP provided to SCCG Expired Denosumab.pdf Disease Modifying agents in Rheumatic disease (DMARDs) For bone metastases (120mg/ml) NICE do not recommended use in primary care so RED status applies Gold Injections Azathioprine Penicillamine Sulfasalazine Ciclosporin Hydroxychloroquine Leflunomide Methotrexate All SCPs expire March 2013 but review is in progress for Stepping Hill Hospital Protocols All SCGs expired Sodium Aurothiomalate.pdf Azathioprine.pdf Penicillamine.pdf Sulfasalazine.pdf Ciclosporin in RA.pdf Hydroxychloroquine. pdf Leflunomide.pdf Disulfiram Dornase alfa Flutamide Fulvestrant Gonadorelin analogues Goserelin/ Leuprorelin Gonadorelin analogues-Goserelin/ Leuprorelin/ Triptorelin Patients must be stable > 3 months before care is shared. Public Health funded Cystic Fibrosis Drug is funded & commissioned by NHS England not CCGs no not locally funded. For Prostate cancer Grey listed – For use only where patient started treatment before December 2011 when NICE TA did not recommend use For new patients status is RED Red as no SCP agreed with SCCG Red as no SCP with SCCG Red as no SCP provided to SCCG Expired -No new patients only for patients initiated before Dec. 2011 Licensed indications only endometriosis, pre-op management prior to endometrial ablation/fibroid surgery, pituitary desensitisation- Goseralin for Breast Ca Fulvestrant inj.pdf ALL Red as no SCP provided to SCCG Red as no SCP provided to SCCG Expired Goserelin.pdf All drugs licensed for Prostate cancer Red as no SCP provided to SCCG Pre-op management prior to endometrial ablation/ fibroid surgery Red as no SCP provided to SCCG Red for precocious puberty, male hypersexuality or unlicensed indications Growth hormone For use in children as per NICE guidance National shared care SCP. To be provided by Hospital Growth hormone Histrelin Hydroxycarbamide For primary and secondary hypopituitarism Red for any other indication in adults Palliative treatment of advanced prostate cancer as per IPNTS recommendations Essential thrombocythaemia or polycythaemia with high risk of complications Hydroxycarbamide Sickle cell disease Hydroxychloroquine Drug is RED for Chronic Myeloid Leukaemia Also listed in DMARDS Red as no SCP provided to SCCG In development with SHH Red as no SCP provided to SCCG Red as no SCP provided to SCCG Red as no SCP provided to SCCG Expired Hydroxychloroquine. pdf Ibandronic acid Breast cancer Expired Ibandronate_shared _care1final.pdf Immunosuppressants See individual drugs Ciclosporin Tacrolimus and Sirolimus Interferon alpha Leukaemia and carcinoid tumours Ketamine Palliative Care use is unlicensed Red as no SCP provided to SCCG Can be used under the direction of a palliative care specialist without a formal shared care Red as no SCP provided to SCCG Use for Chronic Pain Management is RED Lanreotide /Octreotide Licensed indications Leflunomide Also listed in DMARDs Expired Leflunomide.pdf Lisdexamfetamine ** Lisdexamfetamine is an option as per the licensed Indication where methylphenidate is not tolerated or fails to achieve a positive outcome. Use in adults is unlicensed but may be considered when all other treatments have failed. September 2015 isdexamfetamine-V109-2013.pdf Lithium November 2014 Lithium SCG ADULTS Version 2 November 2012.pdf Lithium SCG over 65 Version 2 November 2012.pdf Low molecular weight heparins ( Treatment of VTE) If in doubt about status seek advice from Medicines Management Low molecular weight heparins** If in doubt about status seek advice from Medicines Management Low molecular weight heparins If in doubt about status seek advice from Medicines Management Melatonin Mercaptopurine Extended treatment of VTE in cancer patients i.e.Dalteparin as per Christie SCG. For prophylaxis of DVT in cancer drug is RED Expired Dalteparin Feb2011.pdf Expired Enoxaparin as per UHSM SCG Please note this is an unlicensed indication for this particular drug NB Short term use for prophylaxis in cancer is RED DVT/PE treatment > 2 weeks after event (anticoagulation required but warfarin contraindicated). Enoxaparin.pdf Expired Enoxaparin.pdf Pregnancy – see Tinzaparin (only this LMWH is licensed) SCP under consideration Prophylactic use e.g. immobile patients or those deemed to be at particularly high risk of DVT at home or in care situation. Red as no SCP provided to NHS SCCG Pre and Postoperative prophylaxis is RED and will be provided by the operating Trust even as replavement for warfarin RED Travel – over 8 hours by high risk patients is allowed without shared care Paediatric patients e.g. sleep disorders, ADHD once patient is stabilised using the licensed product (Circadin®) Use of licensed product in adults not recommended Inflammatory bowel diseases Unlicensed but in BNF Green following specialist advice In development April 16 SCP Azathioprine and Mercaptopurine.v1 Apr 14.pdf Methotrexate Oral and parenteral** Rheumatic disease Expired Methotrexate Rheumatic Disease.pdf Crohn’s disease-Unlicensed indication but in the BNF Methylphenidate Psoriasis Shared care should only be accepted once the patient is stabilised (> 3 months) by Pennine Mental Health Team Red as no SCP provided to SCCG Expired Methylphenidate_an d_atomoxetine_in_Adult_ADHD_Version_ Expired Methylphenidate & dexamfetamine_for_child_and_adolscen Modafinil Sleepiness associated with narcolepsy Modafinil for sleepiness associated with narcolepsy.pd NB: For Postural Hypotension, idiopathic sleepiness or excessive sleepiness associated with sleep apnoea or shift work disorder (unlicensed) are all designated RED by GMMMG Mycophenolate mofetil RED of any indication without a shared care. Expired Mycophenolate Mofetil for RA.pdf Octreotide/ Lanreotide Licensed indications Pegvisomant Licensed indications Penicillamine Rheumatoid arthritis Red as no SCP provided to SCCG Red as no SCP provided to SCCG Expired Penicillamine.pdf Rheumatology DMARDS Rheumatoid arthritis- see under DMARD or individual drug All Expired Riluzole Risperidone consta Red as no SCP provided to SCCG Long acting injection of this atypical antipsychotic Expired antipsychotics including LA injections Sirolimus Licensed indications Sulfasalazine For use in Rheumatoid conditions see under DMARDs Red as no SCP provided to SCCG Expired Sulfasalazine.pdf For GI indications Red as no SCP provided to SCCG Tacrolimus Licensed indications Tinzaparin Low molecular weight heparin licensed for prophylactic use in pregnancy but not for treatment of DVT Treatment of spasticity Red as no SCP provided to SCCG SCP under consideration by CCG Tizanidine Tuberculosis, antibiotic therapy Various drugs Shared care no longer applies. Drugs must be initiated by a specialist but then can be prescribed by a GP. In development Red as no SCP provided to SCCG