伊普瑞斯科技有限公司
Express Technology Co., Ltd.
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微囊藻毒素系列：
Microcystin-LR
规格：100µg ， 500µg ， 1mg
Product Specifications
FORMULA: C49H74N10O12
MW: 995.2
CAS NUMBER: 101043-37-2
RTECS: GT2810000
SOURCE/HOST: Isolated from Microcystis aeruginosa.
PURITY: 96%
APPEARANCE: Whitish film adhered to inside of the vial.
SOLUBILITY: Soluble in 100% ethanol, methanol or DMSO.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
USE/STABILITY: Stock solutions are stable for up to 6 months when stored at -20°C.
Unstable at pH>7.7.
HAZARD: VERY TOXIC. HIGHLY IRRITANT. TUMOR PROMOTER.
Product Description
Heptapeptide ester hepatotoxin. Equally potent and selective inhibitor of protein phosphatase 1
(PP1) and
2A (PP2A). PP2B is less sensitive and PP2C is not inhibited up to 4μM. Useful for
affinity-purification of
PP2A. The product is not cell permeable except in liver cells, which appear to have a functional
uptake
system. Has no effect on protein kinases. Frequently contaminates fresh-water lakes and ponds.
Causes
livestock poisonings.
Microcystin-RR
规格：250µg
Product Specifications
FORMULA: C49H75N13O12
MW: 1038.2
CAS NUMBER: 111755-37-4
SOURCE/HOST: Isolated from Microcystis aeruginosa.
PURITY: 95%
APPEARANCE: Lyophilized solid.
SOLUBILITY: Soluble in 80% aqueous methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HAZARD: VERY TOXIC. HIGHLY IRRITANT. TUMOR PROMOTER.
Product Description
Arg-Arg analog of microcystin-LR (Prod. No. ALX-350-012). Hepatotoxic, although found to be up
to
10-fold less toxic than microcystin-LR on i.p. injection in mice. Potent inhibitor of protein
phosphatase 2A
(PP2A).
Microcystin-LW
规格：25µg
Product Specifications
FORMULA: C54H72N8O12
MW: 1025.2
SOURCE/HOST: Isolated from Microcystis aeruginosa.
PURITY: 95%
APPEARANCE: Whitish film adhered to inside of the vial.
SOLUBILITY: Soluble in 100% methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HAZARD: HIGHLY IRRITANT. VERY TOXIC. TUMOR PROMOTER.
Product Description
Analog of microcystin-LR (Prod. No. ALX-350-012) with Trp substituted in place of Arg.
Hydrophobic and
believed to be more cell permeable than other microcystins. May prove useful in biochemical
studies in
intact cells. Microcystin-LW has a characteristically different absorption spectrum compared to
other
microcystins, making it a useful reference compound for HPLC analysis. The Trp confers an
absorption
maximum at 222nm, whereas most microcystins have a characteristic maximum at 239nm.
Microcystin-LF
规格：25µg
Product Specifications
FORMULA: C52H71N7O12
MW: 986.2
SOURCE/HOST: Isolated from Microcystis aeruginosa.
PURITY: 95%
APPEARANCE: Whitish film adhered to inside of the vial.
SOLUBILITY: Soluble in 100% methanol.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HAZARD: HIGHLY IRRITANT. VERY TOXIC. TUMOR PROMOTER.
Product Description
Analog of microcystin-LR (Prod. No. ALX-350-012) with Phe substituted in place of Arg.
Hydrophobic and
believed to be more cell permeable than other microcystins.
Microcystin-YR
规格：25µg
Product Specifications
FORMULA: C52H72N10O13
MW: 1045.2
CAS NUMBER: 101064-48-6
SOURCE/HOST: Isolated from Microcystis aeruginosa.
PURITY: 95%
IDENTITY: Identity determined by MS.
APPEARANCE: Whitish film adhered to inside of the vial.
SOLUBILITY: Soluble in 100% ethanol, methanol or DMSO.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HAZARD: HIGHLY IRRITANT. VERY TOXIC. TUMOR PROMOTER.
Product Description
Analog of microcystin-LR (Prod. No. ALX-350-012) with Tyr substituted in place of Leu. As for all
microcystins the conjugated double bonds in the ADDA moiety cause a characteristic absorption
maximum at 238nm. The Tyr residue in position 2 of microcystin-YR confers an absorption
maximum at
232nm. Potent inhibitor of eukaryotic protein phosphates 1 and 2A. Useful as a reference
compound in
environmental analysis. The hydroxyl group of the Tyr residue may prove useful for linking
microcystin-YR
via conjugation to other chemicals.
Monoclonal Antibody to Microcystin-LR (MC10E7)
规格：200 μg
Product Specifications
CLONE: MC10E7
ISOTYPE: Mouse IgG1
IMMUNOGEN: Microcystin-LR linked via N-methyl-dehydroalanine to cationized
ovalbumin.
SPECIFICITY: Recognizes all 4-Arg microcystins.
APPLICATION: ELISA (1:10'000-1:100'000)
Microcystin concentrations can be measured in the range of
~0.006μg/l to 0.3μg/l. The ELISA sensitivity is about 1'000 times
higher compared to UV detection.
FORMULATION: Lyophilized from antibody purified by protein G affinity
chromatography.
RECONSTITUTION: Reconstitute with 200μl PBS containing sodium azide.
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Storage at 4°C will decrease antibody activity and must be avoided.
HANDLING: Avoid freeze/thaw cycles. After opening, prepare aliquots and store
at -20°C.
Product Description
With a direct competitive enzyme-linked immunosorbent assay (ELISA) using antibody MC10E7,
IC50
values for microcystin-LR of 0.06 μg/l have been obtained. The provisional guideline value
proposed by
the WHO is 1 μg/l for drinking water. The detection limit for microcystin-LR is 0.006 μg/l. All
microcystin
variants containing an arginine at position 4 show similar IC50 values and detection limits,
whereas other
microcystins, such as microcystin-LA are not recognized. The affinity constant for MC10E7 was
determined to be at least 7 x 1010 l/mol.
The antibody was tested for its robustness against interferences (humic acids, pH, salt content,
surfactants or organic solvents) and was found to be very stable. Microcystin-LR spiked water
samples in
the concentration range between 0.01 and 0.1 μg/l were measured and a mean recovery of 99.9 ±
16.4%
was found. The antibody is well suited for the sensitive analysis of microcystins in drinking as well
as
surface water.
Monoclonal Antibody to Microcystins (Addaspecific) (AD4G2)
规格：100 μg
Product Specifications
CLONE: AD4G2
ISOTYPE: Mouse IgG1
IMMUNOGEN: N-Acetyl-Adda-KLH and N-Acetyl-Adda-BSA.
SPECIFICITY: Recognizes all microcystins.
APPLICATION: ELISA (1:10'000)
Microcystins can be measured at a detection limit of ~0.03μg/l.
FORMULATION: Lyophilized.
RECONSTITUTION: Reconstitute with 100μl PBS containing sodium azide.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: After reconstitution, prepare aliquots and store at -20°C. Avoid
freeze/thaw cycles.
POSITIVE CONTROL: Products No. ALX-350-012, ALX-350-043, ALX-350-080 and
ALX-350-081.
Product Description
With a direct competitive enzyme-linked immunosorbent assay (ELISA) using antibody AD4G2,
IC50
values for microcystin-LR of 0.06 μg/l have been obtained. The provisional guideline value
proposed by
the WHO is 1μg/l for drinking water. The detection limit for microcystin-LR is 0.07μg/l. All
microcystin
variants show similar IC50 values and detection limits. No microcystins are known, that are not
recognized
by this antibody. Microcystin-LR spiked water samples in the concentration range between 0.1 and
1μg/l
were measured and a mean recovery of 113 ± 23% was found. The antibody is well suited for the
sensitive analysis of all microcystins in drinking as well as surface water. Due to the very even
cross-reactivity pattern of the antibody, a calibration with one microcystin (preferably MC-LR)
(Prod. No.
ALX-350-012) is sufficient for the quantitative determination of a sum concentration of all
microcystins
contained in a a sample.
Nodularin
规格：10ug , 100ug , 250ug
Product Specifications
FORMULA: C41H60N8O10
MW: 825.0
CAS NUMBER: 118399-22-7
SOURCE/HOST: Isolated from Nodularia spumigena.
PURITY: 96%
APPEARANCE: Dry residue containing traces of monobasic potassium phosphate.
SOLUBILITY: Soluble in methanol:water (1:1).
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HAZARD: TUMOR PROMOTER. HIGHLY IRRITANT.
Product Description
Inhibitor of protein phosphatase 1 (PP1) (IC50=1.8nM), protein phosphatase 2A (PP2A) (IC50
=0.026nM) and to a lesser extent protein phosphatase 2B (PP2B) (IC50=8.7μm). Similar to
microcystin-LR
(Prod. No. ALX-350-012) but with increased water solubility.
伊普瑞斯科技有限公司
www.express-cn.com
info@express-cn.com
kanyinbi@163.com
010-60206266
联系人：Colin Kan(阚先生)