SCHOOL OF BIOMEDICAL SCIENCES RESEARCH PUBLICATIONS @ 12-8-2009 1. Adams, V., G.A. Challen, E. Zuba-Surma, H. Ulrich, G. Vereb, and A. Tarnok, EDITORIAL: Where new approaches can stem from: focus on stem cell identification. Cytometry A, 2009. 75(1): p. 1-3 Category: Biochemical Research Methods Impact Factor: 3.259 Ranking: 19/65 [ANT] 2. Adler, B. and A. de la Pena Moctezuma, REVIEW: Leptospira and leptospirosis. Vet Microbiol, 2009. E-Pub Category: Microbiology Impact Factor: 2.370 Ranking: 40/91 [MICRO] 3. Aguilar, M.I., T.-H. Lee, B. Catimel, and E.C. Nice, Miniaturization of Highperformance liquid chromatographic separations and equipment in peptide and protein analysis, miniaturization of, in Encyclopedia of Analytical Chemistry. 2009, John Wiley & Sons Ltd. p. 1-21. 4. Allen, J.E., R.J. Bischof, H.Y. Sucie Chang, J.A. Hirota, S.J. Hirst, M.D. Inman, W. Mitzner, and T.E. Sutherland, Animal models of airway inflammation and airway smooth muscle remodelling in asthma. Pulm Pharmacol Ther, 2009. E-Pub Category: Respiratory System Impact Factor: 2.283 Ranking: 17/40 [PHY] 5. Alves, N.L., O.R. Goff, N.D. Huntington, A.P. Sousa, V.S. Ribeiro, A. Bordack, F.L. Vives, L. Peduto, A. Chidgey, A. Cumano, R. Boyd, G. Eberl, and J.P. Di Santo, Characterization of the thymic IL-7 niche in vivo. Proc Natl Acad Sci U S A, 2009. 106(5): p. 1512-1517 Category: Multidisciplinary Sciences Impact Factor: 9.380 Ranking: 3/42 [MISCL] 6. Alvisi, G., D.M. Roth, D. Camozzi, G.S. Pari, A. Loregian, A. Ripalti, and D.A. Jans, The flexible loop of human cytomegalovirus DNA polymerase processivity factor ppUL44 is required for efficient DNA binding and replication in cells. J Virol, 2009. EPub Category: Virology Impact Factor: 5.308 Ranking: 3/27 [BCH] 7. Ambrose, Z., B.D. Herman, C.W. Sheen, S. Zelina, K.L. Moore, G. Tachedjian, D.V. Nissley, and N. Sluis-Cremer, The human immunodeficiency virus type 1 (HIV-1) nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs. J Virol, 2009. 83(8): p. 3826-3833 Category: Virology Impact Factor: 5.308 Ranking: 3/27 [MICRO] 8. Andrews, K.L., J.C. Irvine, M. Tare, J. Apostolopoulos, J.L. Favaloro, C.R. Triggle, and B.K. Kemp-Harper, A role for nitroxyl (HNO) as an endotheliumderived relaxing and hyperpolarizing factor in resistance arteries. Br J Pharmacol, 2009. 157(4): p. 540-550 Category: Pharmacology & Pharmacy Impact Factor: 4.902 Ranking: 18/216 [PHARM,PHY] 9. Andrews, Z.B. and T. Horvath, Uncoupling Protein 2 regulates lifespan in mice. Am J Physiol Endocrinol Metab, 2009. 296(4): p. E621-E627 Category: Physiology Impact Factor: 3.855 Ranking: 14/74 [PHY] -1- 10. Anukulkitch, C., A. Rao, F.R. Dunshea, and I.J. Clarke, A test of the lipostat theory in a seasonal (ovine) model under natural conditions reveals close relationship between adiposity and melanin concentrating hormone expression. Domest Anim Endocrinol, 2009. 36(3): p. 138-151 Category: Endocrinology & Metabolism Impact Factor: 2.165 Ranking: 62/93 [PHY] 11. Archbold, J.K., W.A. Macdonald, S. Gras, L.K. Ely, J.J. Miles, M.J. Bell, R.M. Brennan, T. Beddoe, M.C. Wilce, C.S. Clements, A.W. Purcell, J. McCluskey, S.R. Burrows, and J. Rossjohn, Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition. J Exp Med, 2009. 206(1): p. 209-19 Category: Immunology Impact Factor: 15.219 Ranking: 5/121 [BCH] 12. Aurelio, L., C. Valant, B.L. Flynn, P.M. Sexton, A. Christopoulos, and P.J. Scammells, Allosteric Modulators of the Adenosine A(1) Receptor: Synthesis and Pharmacological Evaluation of 4-Substituted 2-Amino-3-benzoylthiophenes. J Med Chem, 2009. 52(14): p. 4543-4537 Category: Medicinal Chemistry Impact Factor: 4.898 Ranking: 3/40 [PHARM] 13. Badea, L., S.A. Beatson, M. Kaparakis, R.L. Ferrero, and E.L. Hartland, Secretion of flagellin by the LEE-encoded type III secretion system of enteropathogenic Escherichia coli. BMC Microbiol, 2009. 9(30): p. 1-10 Category: Microbiology Impact Factor: 2.877 Ranking: 28/91 [MICRO] 14. Bailey, S.R., S. Boustany, J.K. Burgess, S.J. Hirst, H.S. Sharma, D.E. Simcock, P.R. Suravaram, and M. Weckmann, Airway vascular reactivity and vascularisation in human chronic airway disease. Pulm Pharmacol Ther, 2009. E-Pub Category: Respiratory System Impact Factor: 2.283 Ranking: 17/40 [PHY] 15. Baran, K., M. Dunstone, J. Chia, A. Ciccone, K.A. Browne, C.J. Clarke, N. Lukoyanova, H. Saibil, J.C. Whisstock, I. Voskoboinik, and J.A. Trapani, The molecular basis for perforin oligomerization and transmembrane pore assembly. Immunity, 2009. 30(5): p. 684-95 Category: Immunology Impact Factor: 20.579 Ranking: 4/121 [BCH,MICRO] 16. Barken, K.B., S.J. Pamp, L. Yang, M. Gjermansen, J.J. Bertrand, M. Klausen, M. Givskov, C.B. Whitchurch, J.N. Engel, and T. Tolker-Nielsen, Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures in Pseudomonas aeruginosa biofilms. Environ Microbiol, 2008. 10(9): p. 2331-2343 Category: Microbiology Impact Factor: 4.929 Ranking: 12/94 [MICRO] 17. Barry, E.F., F.A. Felquer, J.A. Powell, L. Biggs, F.C. Stomski, A. Urbani, P. Hoffmann, M.C. Wilce, M.A. Grimbaldeston, A.F. Lopez, and M.A. Guthridge, 14-3-3:SHC scaffolds integrate phoshoserine and phosphotyrosine signaling to regulate PI 3kinase activation and cell survival. J Biol Chem, 2009. 284(18): p. 12080-12090 Category: Biochemistry & Molecular Biology Impact Factor: 5.520 Ranking: 41/276 [BCH] 18. Baskurt, O.K., M. Boynard, G.C. Cokelet, P. Connes, B.M. Cooke, S. Forconi, F. Liao, M.R. Hardeman, F. Jung, H.J. Meiselman, G. Nash, N. Nemeth, B. Neu, B. Sandhagen, S. Shin, G. Thurston, and J.L. Wautier, New guidelines for hemorheological laboratory techniques. Clin Hemorheol Microcirc, 2009. 42(2): p. 75-97 Category: Hematology Impact Factor: 1.814 Ranking: 45/62 [MICRO] -2- 19. Beckham, S.A., D. Piedrafita, C.I. Phillips, N. Samarawickrema, R.H. Law, P.M. Smooker, N.S. Quinsey, J.A. Irving, D. Greenwood, S.H. Verhelst, M. Bogyo, B. Turk, T.H. Coetzer, L.C. Wijeyewickrema, T.W. Spithill, and R.N. Pike, A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites. Int J Biochem Cell Biol, 2009. 41(7): p. 1601-12 Category: Biochemistry & Molecular Biology Impact Factor: 4.178 Ranking: 73/276 [BCH,PHY] 20. Beddoe, T., Z. Chen, C.S. Clements, L.K. Ely, S.R. Bushell, J.P. Vivian, L. KjerNielsen, S.S. Pang, M.A. Dunstone, Y.C. Liu, W.A. Macdonald, M.A. Perugini, M.C. Wilce, S.R. Burrows, A.W. Purcell, T. Tiganis, S.P. Bottomley, J. McCluskey, and J. Rossjohn, Antigen Ligation Triggers a Conformational Change within the Constant Domain of the alphabeta T Cell Receptor. Immunity, 2009. 30(6): p. 777788 Category: Immunology Impact Factor: 20.579 Ranking: 4/121 [BCH] 21. Bell, M.J., J.M. Burrows, R. Brennan, J.J. Miles, J. Tellam, J. McCluskey, J. Rossjohn, R. Khanna, and S.R. Burrows, SHORT COMMUNICATION: The peptide length specificity of some HLA class I alleles is very broad and includes peptides of up to 25 amino acids in length. Mol Immunol, 2009. E-Pub: p. 1-7 Category: Biochemistry & Molecular Biology Impact Factor: 3.555 Ranking: 89/276 [BCH] 22. Bergstrom, F.C., S. Reynolds, M. Johnstone, R.N. Pike, A.M. Buckle, D.J. Kemp, K. Fischer, and A.M. Blom, Scabies mite inactivated serine protease paralogs inhibit the human complement system. J Immunol, 2009. 182(12): p. 7809-17 Category: Immunology Impact Factor: 6.000 Ranking: 16/121 [BCH] 23. Bernstein, I.D., R.L. Boyd, and M.R. Van den Brink, INTRODUCTION: Clinical strategies to enhance posttransplant immune reconstitution. Biol Blood Marrow Tr, 2008. 14(1 Suppl.): p. 94-99 Category: Hematology Impact Factor: 3.797 Ranking: 15/63 [MISCL] 24. Boyce, J.D., M. Harper, F. St Michael, M. John, A. Aubry, H. Parnas, S.M. Logan, I.W. Wilkie, M. Ford, A.D. Cox, and B. Adler, Identification of novel glycosyltransferases required for assembly of the Pasteurella multocida A:1 lipopolysaccharide and their involvement in virulence. Infect Immun, 2009. 77(4): p. 1532-1542 Category: Infectious Diseases Impact Factor: 3.987 Ranking:10/51 [MICRO] 25. Boyd, R.L., J. Sutherland, T. Heng, G. Goldberg, D. Gray, A. Fletcher, N. Seach, and A.P. Chidgey, Manipulation of the thymus and bone marrow to improve engraftment and restoration of immune competence un autologous and allogeneic HSCT. Biology of Blood and Marrow Transplantation, 2008. 14(1 Suppl.): p. 97-99 Category: Hematology Impact Factor: 3.797 Ranking: 15/63 [MISCL] 26. Boyd, S.E., F.K. Kerr, D.W. Albrecht, M.G. de la Banda, N. Ng, and R.N. Pike, Cooperative effects in the substrate specificity of the complement protease C1s. Biol Chem, 2009. 390(5-6): p. 503-507 Category: Biochemistry & Molecular Biology Impact Factor: 3.035 Ranking: 113/276 [BCH] -3- 27. Bracho, G., C. Zayas, L. Wang, R. Coppel, O. Perez, and N. Petrovsky, AFCo1, a meningococcal B-derived cochleate adjuvant, strongly enhances antibody and T-cell immunity against Plasmodium falciparum merozoite surface protein 4 and 5. Malar J, 2009. 8: p. 1-10 Category: Parasitology Impact Factor: 2.913 Ranking: 7/25 [MICRO] 28. Broughton, B.R., D.C. Reutens, and C.G. Sobey, Apoptotic Mechanisms After Cerebral Ischemia. Stroke, 2009. 40(5): p. e331-e339 Category: Clinical Neurology Impact Factor: 6.499 Ranking: 6/156 [PHARM] 29. Brown, K.A., K.J. McInnes, N.I. Hunger, J.S. Oakhill, G.R. Steinberg, and E.R. Simpson, Subcellular Localization of Cyclic AMP-Responsive Element Binding Protein-Regulated Transcription Coactivator 2 Provides a Link between Obesity and Breast Cancer in Postmenopausal Women. Cancer Res, 2009. 69(13): p. 5392-5399 Category: Oncoloty Impact Factor: 7.514 Ranking: 12/141 [PHY,BCH] 30. Bruce, C.R., A.J. Hoy, N. Turner, M.J. Watt, T.L. Allen, K. Carpenter, G.J. Cooney, M.A. Febbraio, and E.W. Kraegen, Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high fat diet-induced insulin resistance. Diabetes, 2009. 58(3): p. 550-559 Category: Endocrinology & Metabolism Impact Factor: 8.398 Ranking: 4/93 [PHY] 31. Burman, K.J. and M.G. Rosa, Architectural subdivisions of medial and orbital frontal cortices in the marmoset monkey (Callithrix jacchus). J Comp Neurol, 2009. 514(1): p. 11-29 Category: Zoology Impact Factor: 3.743 Ranking: 3/125 [PHY] 32. Challen, G.A., N. Boles, K.K. Lin, and M.A. Goodell, REVIEW: Mouse hematopoietic stem cell identification and analysis. Cytometry A, 2009. 75(1): p. 14-24 Category: Biochemical Research Methods Impact Factor: 3.259 Ranking: 19/65 [ANT] 33. Challen, G.A. and M.A. Goodell, Promiscuous expression of H2B-GFP transgene in hematopoietic stem cells. PLoS ONE, 2008. 3(6): p. e2357 [ANT] 34. Chand, A.L., K.C. Fab, E.R. Simpson, and C.D. Clyne, Aromatase expression is increased in BRCA1 mutation carriers. BMC Cancer, 2009. 9(1): p. 148 Category: Oncology Impact Factor: 3.087 Ranking: 59/141 [BCH] 35. Chaouche-Drider, N., M. Kaparakis, A. Karrar, M.I. Fernandez, L.A. Carneiro, J. Viala, I.G. Boneca, A.P. Moran, D.J. Philpott, and R.L. Ferrero, A commensal Helicobacter sp. of the rodent intestinal flora activates TLR2 and NOD1 responses in epithelial cells. PLoS ONE, 2009. 4(4): p. e5396-1-e5396-10 [MICRO] 36. Cheung, J.K., M.M. Awad, S. McGowan, and J.I. Rood, Functional analysis of the VirSR phosphorelay from Clostridium perfringens. PLoS ONE, 2009. 4(6): p. e5849 [MICRO,BCH] 37. Chia, J., K.P. Yeo, J.C. Whisstock, M.A. Dunstone, J.A. Trapani, and I. Voskoboinik, Temperature sensitivity of human perforin mutants unmasks subtotal loss of cytotoxicity, delayed FHL, and a predisposition to cancer. Proc Natl Acad Sci U S A, 2009. 106(24): p. 9809-9814 Category: Multidisciplinary Sciences Impact Factor: 9.380 Ranking: 3/42 [BCH,MICRO] -4- 38. Chow, J.D., E.R. Simpson, and W.C. Boon, Alternative 5'-untranslated first exons of the mouse Cyp19A1 (aromatase) gene. J Steroid Biochem Mol Biol, 2009. 115(35): p. 115-25 Category: Biochemistry & Molecular Biology Impact Factor: 2.827 Ranking: 122/276 [ANT,BCH] 39. Clarke, I.J., Y. Qi, I.P. Sari, and J.T. Smith, REVIEW: Evidence that RF-amide Related Peptides are Inhibitors of Reproduction in Mammals. Front Neuroendocrinol, 2009. E-Pub Category: Endocrinology & Metabolism Impact Factor: 8.692 Ranking: 3/93 [PHY] 40. Clayton, D., I. Hanchapola, P. Perlmutter, A.I. Smith, and M.I. Aguilar, The active site specificity of angiotensin converting Enzyme 2 investigated tghrough single and multiple residue changes and {beta}-amino acid substrate analogs, in Adv Exp Med Biol-Peptides for Youth, E.E.W.L. S Del Valle, Editor. 2008, Springer New York LLC: USA. p. 559-560. [BCH] 41. Comper, W.D., LETTER TO THE EDITOR: Is the LPS-mediated proteinuria mouse model relevant to human kidney disease? Nat Med, 2009. 15(2): p. 133; author reply 133-4 Category: Biochemistry & Molecular Biology Impact Factor: 27.553 Ranking: 3/276 [BCH] 42. Comper, W.D., B. Haraldsson, and W.M. Deen, Resolved: normal glomeruli filter nephrotic levels of albumin. J Am Soc Nephrol, 2008. 19(3): p. 427-32 Category: Urology & Nephrology Impact Factor: 7.111 Ranking: 1/55 [BCH] 43. Comper, W.D., L.M. Hilliard, D.J. Nikolic-Paterson, and L.M. Russo, REVIEW: Disease-dependent mechanisms of albuminuria. Am J Physiol Renal Physiol, 2008. 295(6): p. F1589-600 Category: Urology & Nephrology Impact Factor: 4.416 Ranking: 6/55 [BCH,PHY] 44. Comper, W.D. and L.M. Russo, REVIEW: Where does albu minuria come from in diabetic kidney disease? Curr Diab Rep, 2008. 8(6): p. 477-485 [BCH] 45. Comper, W.D. and L.M. Russo, The glomerular filter: an imperfect barrier is required for perfect renal function. Curr Opin Nephrol Hypertens, 2009. 18(4): p. 336-342 Category: Urology & Nephrology Impact Factor: 4.000 Ranking: 8/57 [BCH] 46. Conn, P.J., A. Christopoulos, and C.W. Lindsley, REVIEW: Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders. Nat Rev Drug Discov, 2009. 8(1): p. 41-54 Category: Pharmacology & Pharmacy Impact Factor: 28.690 Ranking: 1/216 [PHARM] 47. Coppel, R.L., REVIEW: Vaccinating with the genome: a Sisyphean task? Trends Parasitol, 2009. 25(5): p. 205-212 Category: Parasitology Impact Factor: 4.690 Ranking: 3/25 [MICRO] 48. Cottle, D.L., M.J. McGrath, B.R. Wilding, B.S. Cowling, J.M. Kane, C.E. D'Arcy, M. Holdsworth, I. Hatzinisiriou, M. Prescott, S. Brown, and C.A. Mitchell, Slimmer (FHl1B / KYOT3) interacts with the pro-apoptotic protein siva-1 (CD27BP) and delays skeletal myoblast apoptosis. J Biol Chem, 2009. E-Pub Category: Biochemistry & Molecular Biology Impact Factor: 5.520 Ranking: 41/276 [BCH] -5- 49. Crossley, K.J., C.J. Morley, B.J. Allison, P.G. Davis, G.R. Polglase, M.J. Wallace, V.A. Zahra, and S.B. Hooper, Antenatal Corticosteroids Increase Fetal, But Not Postnatal, Pulmonary Blood Flow In Sheep. Pediatr Res, 2009. E-Pub Category: Pediatrics Impact Factor: 2.604 Ranking: 15/86 [PHY] 50. Crowe, S., L.E. Wu, C. Economou, S.M. Turpin, M. Matzaris, K.L. Hoehn, A.L. Hevener, D.E. James, E.J. Duh, and M.J. Watt, SHORT ARTICLE: Pigment epithelium-derived factor contributes to insulin resistance in obesity. Cell Metab, 2009. 10(1): p. 40-7 Category: Cell Biology Impact Factor: 16.107 Ranking: 7/157 [PHY] 51. Dagley, M.J., P. Dolezal, V.A. Likic, O. Smid, A.W. Purcell, S.K. Buchanan, J. Tachezy, and T. Lithgow, The protein import channel in the outer mitosomal membrane of Giardia intestinalis. Mol Biol Evol, 2009. E-Pub Category: Biochemistry & Molecular Biology Impact Factor: 7.280 Ranking: 27/276 [BCH] 52. De Silva, T.M., B.R. Broughton, G.R. Drummond, C.G. Sobey, and A.A. Miller, Gender influences cerebral vascular responses to angiotensin II through Nox2derived reactive oxygen species. Stroke, 2009. 40(4): p. 1091-1097 Category: Clinical Neurology Impact Factor: 6.499 Ranking: 6/156 [PHARM] 53. Demangel, C., T.P. Stinear, and S.T. Cole, REVIEW: Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans. Nat Rev Microbiol, 2009. 7(1): p. 50-60 Category: Microbiology Impact Factor: 14.310 Ranking: 3/91 [MICRO] 54. Dey, A., D.T. Nguyen, R.J. Lang, and B. Exintaris, Spontaneous Electrical Waveforms in Aging Guinea Pig Prostates. J Urol, 2009. 181(6): p. 2797-2805 Category: Urology & Nephrology Impact Factor: 3.952 Ranking: 9/57 [PHY] 55. Diwakarla, S., L.D. Mercer, L. Kardashsyan, P.W. Chu, Y.S. Shin, C.L. Lau, M.L. Hughes, P. Nagley, and P.M. Beart, GABAergic striatal neurons exhibit caspaseindependent, mitochondrially mediated programmed cell death. J Neurochem, 2009. 109(Suppl 1): p. 198-206 Category: Biochemistry & Molecular Biology Impact Factor: 4.500 Ranking: 60/276 [BCH] 56. Dudakov, J.A., G.L. Goldberg, J.J. Reiseger, A.P. Chidgey, and R.L. Boyd, Withdrawal of sex steroids reverses age- and chemotherapy-related defects in bone marrow lymphopoiesis. J Immunol, 2009. 182(10): p. 6247-60 Category: Immunology Impact Factor: 6.000 Ranking: 16/121 [MICSL] 57. Ebert, L.M., Y.C. Liu, C.S. Clements, N.C. Robson, H.M. Jackson, J.L. Markby, N. Dimopoulos, B.S. Tan, I.F. Luescher, I.D. Davis, J. Rossjohn, J. Cebon, A.W. Purcell, and W. Chen, A Long, Naturally Presented Immunodominant Epitope from NY-ESO-1 Tumor Antigen: Implications for Cancer Vaccine Design. Cancer Res, 2009. 69(3): p. 1046-1054 Category: Oncology Impact Factor: 7.514 Ranking: 12/141 [BCH] 58. Elefanty, A., EDITORIAL: ESTOOLS, a project funded by the European Commission(FP6), gathers expertise on human embryonic stem cells in 10 countries of the European Research Area. Stem Cell Res, 2009. 2(2): p. 95-6 [MISCL] -6- 59. Elefanty, A., EDITORIAL: In this Issue.....This review explores the various stem and progenitor cell populations that are resident in the microvasculature, endothelium, and vessel walls. Stem Cell Res, 2009. 2(1): p. 1 [MISCL] 60. Elefanty, A., EDITORIAL: Stem Cell Research. In this issue.....On behalf of the editors of Stem Cell Research.... Stem Cell Res, 2009. 2(3): p. 163-164 [MISCL] 61. Eppel, G.A., D. Lo Jacono, M. Shirai, K. Umetani, R.G. Evans, and J.T. Pearson, Contrast angiography of the rat renal microcirculation in vivo using synchrotron radiation. Am J Physiol Renal Physiol, 2009. 296(5): p. F1023-F1031 Category: Physiology Impact Factor: 3.890 Ranking: 13/74 [PHY] 62. Evans, R.G., G.A. Head, G.A. Eppel, S.L. Burke, and N.W. Rajapakse, Angiotensin II and neurohumoral control of the renal medullary circulation. Clin Exp Pharmacol Physiol, 2009. E-Pub Category: Physiology Impact Factor: 2.196 Ranking: 38/74 [PHY] 63. Evans, R.G. and C.N. May, EDITORIAL: Tissue hypoxia as a therapeutic target in acute kidney injury. Clin Exp Pharmacol Physiol, 2009. E-Pub Category: Pharmacology & Pharmacy Impact Factor: 2.196 Ranking: 114/216 [PHY] 64. Everitt, S., R.J. Hicks, D. Ball, T. Kron, M. Schneider-Kolsky, T. Walter, D. Binns, and M. Mac Manus, Imaging Cellular Proliferation During Chemo-Radiotherapy: A Pilot Study of Serial (18)F-FLT Positron Emission Tomography/Computed Tomography Imaging for Non-Small-Cell Lung Cancer. Int J Radiat Oncol Biol Phys, 2009. E-Pub Category: Radiology, Nuclear Medicine & Medical Imaging Impact Factor: 4.639 Ranking: 7/90 [RAD] 65. Exintaris, B., T.N. DT, M. Lam, and R.J. Lang, Inositol trisphosphate-dependent Ca(2+) stores and mitochondria modulate slow wave activity arising from the smooth muscle cells of the guinea pig prostate gland. Br J Pharmacol, 2009. 156(7): p. 1098-1106 Category: Pharmacology & Pharmacy Impact Factor: 4.902 Ranking: 18/216 [PHY] 66. Favaloro, J.L. and B.K. Kemp-Harper, Redox variants of nitric oxide (NO* and HNO) elicit vasorelaxation of resistance arteries via distinct mechanisms. Am J Physiol Heart Circ Physiol, 2009. 296(5): p. H1274-H1280 Category: Cardiac & Cardiovascular Impact Factor: 3.643 Ranking: 19/78 [PHARM] 67. Fenalti, G. and A.M. Buckle, Structural biology of the GAD autoantigen. Autoimmun Rev, 2009. E-Pub Category: Immunology Impact Factor: 5.371 Ranking: 18/121 [BCH] 68. Fischer, K., C.G. Langendorf, J.A. Irving, S. Reynolds, C. Willis, S. Beckham, R.H. Law, S. Yang, T.A. Bashtannyk-Puhalovich, S. McGowan, J.C. Whisstock, R.N. Pike, D.J. Kemp, and A.M. Buckle, Structural Mechanisms of Inactivation in Scabies Mite Serine Protease Paralogues. J Mol Biol, 2009. 390(4): p. 635-645 Category: Biochemistry & Molecular Biology Impact Factor: 4.146 Ranking: 74/276 [BCH] -7- 69. Fitzpatrick, R.E., L.C. Wijeyewickrema, and R.N. Pike, REVIEW: The gingipains: scissors and glue of the periodontal pathogen, Porphyromonas gingivalis. Future Microbiol, 2009. 4(4): p. 471-87 Category: Microbiology Impact Factor: 1.976 Ranking: 55/91 [BCH] 70. Fletcher, A.L., T.E. Lowen, S. Sakkal, J.J. Reiseger, M.V. Hammett, N. Seach, H.S. Scott, R.L. Boyd, and A.P. Chidgey, Ablation and regeneration of toleranceinducing medullary thymic epithelial cells after cyclosporine, cyclophosphamide, and dexamethasone treatment. J Immunol, 2009. 183(2): p. 823-31 Category: Immunology Impact Factor: 6.000 Ranking: 16/121 [MISCL] 71. Fletcher, A.L., N. Seach, J.J. Reiseger, T.E. Lowen, M.V. Hammett, H.S. Scott, and R.L. Boyd, Reduced thymic Aire expression and abnormal NF-kappaB2 signaling in a model of systemic autoimmunity. J Immunol, 2009. 182(5): p. 2690-9 Category: Immunology Impact Factor: 6.000 Ranking: 16/121 [MISCL] 72. Fry, B.G., S. Wroe, W. Teeuwisse, M.J. van Osch, K. Moreno, J. Ingle, C. McHenry, T. Ferrara, P. Clausen, H. Scheib, K.L. Winter, L. Greisman, K. Roelants, L. van der Weerd, C.J. Clemente, E. Giannakis, W.C. Hodgson, S. Luz, P. Martelli, K. Krishnasamy, E. Kochva, H.F. Kwok, D. Scanlon, J. Karas, D.M. Citron, E.J. Goldstein, J.E. McNaughtan, and J.A. Norman, A central role for venom in predation by Varanus komodoensis (Komodo Dragon) and the extinct giant Varanus (Megalania) priscus. Proc Natl Acad Sci U S A, 2009. 106(22): p. 8969-8974 Category: Multidisciplinary Sciences Impact Factor: 9.380 Ranking: 3/42 [PHARM] 73. Gao, F., K.G. Harikumar, M. Dong, P.C. Lam, P.M. Sexton, A. Christopoulos, A. Bordner, R. Abagyan, and L.J. Miller, Functional importance of a structurally-distinct homo-dimeric complex of the Family B G protein-coupled secretin receptor. Mol Pharmacol, 2009. 76(2): p. 264-274 Category: Pharmacology & Pharmacy Impact Factor: 4.711 Ranking: 22/216 [PHARM] 74. Geng, G., L.A. Johnston, E. Yan, J.M. Britto, D.W. Smith, D.W. Walker, and G.F. Egan, Biomechanisms for modelling cerebral cortical folding. Med Image Anal, 2009. E-Pub: p. 1-11 Category: Computer Science - Interdisciplinary applications Impact Factor: 3.602 Ranking: 4/94 [PHY] 75. Ghildyal, R., A. Ho, M. Dias, L. Soegiyono, P.G. Bardin, K.C. Tran, M.N. Teng, and D.A. Jans, The Respiratory Syncytial Virus Matrix Protein Possesses a Crm1Mediated Nuclear Export Mechanism. J Virol, 2009. 83(11): p. 5353-5362 Category: Virology Impact Factor: 5.308 Ranking: 3/27 [BCH] 76. Ghildyal, R., B. Jordan, D. Li, H. Dagher, P.G. Bardin, J.E. Gern, and D.A. Jans, Rhinovirus 3c Protease Can Localise in the Nucleus and Alter Active and Passive Nucleocytoplasmic Transport. J Virol, 2009. 83(14): p. 7349-7352 Category: Virology Impact Factor: 5.308 Ranking: 3/27 [BCH] 77. Gibbs, M.E. and D.N. Bowser, Astrocytes and Interneurons in Memory Processing in the Chick Hippocampus: Roles for G-Coupled Protein Receptors, GABA(B) and mGluR1. Neurochem Res, 2009. E-Pub Category: Biochemistry & Molecular Biology Impact Factor: 2.260 Ranking: 162/276 [ANT] -8- 78. Gibbs, M.E., Z. Gibbs, and L. Hertz, Rescue of A{beta}(1-42)-induced memory impairment in day-old chick by facilitation of astrocytic oxidative metabolism: implications for Alzheimer's disease. J Neurochem, 2009. 109 Suppl 1: p. 230-6 Category: Neuroscience Impact Factor: 4.500 Ranking: 40/219 [ANT] 79. Glenister, F.K., K.M. Fernandez, L.M. Kats, E. Hanssen, N. Mohandas, R.L. Coppel, and B.M. Cooke, Functional alteration of red blood cells by a Mega-Dalton protein of Plasmodium falciparum. Blood, 2009. 113(4): p. 919-928 Category: Hematology Impact Factor: 10.432 Ranking: 2/62 [MICRO] 80. Glover, D.J., S.M. Ng, A. Mechler, L.L. Martin, and D.A. Jans, Multifunctional protein nanocarriers for targeted nuclear gene delivery in nondividing cells. Faseb J, 2009. E-Pub Category: Biochemistry & Molecular Biology Impact Factor: 7.049 Ranking: 31/276 [BCH] 81. Gold, E., N. Jetly, M.K. O'Bryan, S. Meachem, D. Srinivasan, S. Behuria, L.G. Sanchez-Partida, T. Woodruff, S. Hedwards, H. Wang, H. McDougall, V. Casey, B. Niranjan, S. Patella, and G. Risbridger, Activin C antagonizes activin A in vitro and overexpression leads to pathologies in vivo. 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Lemasurier, F. Olsson, T. Dang, J. Yao, M. Yang, M. Plebanski, D.J. Phillips, R.A. Mollard, J.M. Rolland, and R. O'Hehir, IL-13 Regulates Secretion of the TGF-{beta} Superfamily Cytokine Activin A in Allergic Airway Inflammation. Am J Respir Cell Mol Biol, 2009. E-Pub Category: Cell Biology Impact Factor: 4.477 Ranking: 49/157 [BCH] 92. Haylor, J.L., E. Parker, G.P. Risbridger, D. Beale, B.L. Brown, P.R. Dobson, I.J. Clarke, and J.E. Hart, Inhibition of compensatory renal growth by the N-terminus of a sheep-derived peptide. Regul Pept, 2009. 152(1-3): p. 48-53 Category: Physiology Impact Factor: 2.422 Ranking: 33/78 [PHY] 93. Henriques, S., L. Pattenden, M.I. Aguilar, and M. Castanho, The toxicity of prion protein fragment PrP(106-126) is not mediated by membrane permeabilization as shown by a M112W substitution. Biochemistry, 2009. 48(19): p. 4198-4208 Category: Biochemistry & Molecular Biology Impact Factor: 3.379 Ranking: 96/276 [BCH] 94. Henry, B.A., F.R. Dunshea, M. 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Holland, A.M. and E.G. Stanley, Stem Cells and the price of immortality. Stem Cell Res, 2009. 2(1): p. 26-28 [MISCL] 102. Hooper, S.B., M.J. Kitchen, M.L. Siew, R.A. Lewis, A. Fouras, A.B. te Pas, K.K. Siu, N. Yagi, K. Uesugi, and M.J. Wallace, REVIEW: Imaging lung aeration and lung liquid clearance at birth using phase contrast X-ray imaging. Clin Exp Pharmacol Physiol, 2009. 36(1): p. 117-25 Category: Pharmacology & Pharmacy Impact Factor: 2.196 Ranking: 114/216 [PHY] 103. Hoppe, C.C., K.M. Moritz, S.M. Fitzgerald, J.F. Bertram, and R.G. Evans, Transient hypertension and sustained tachycardia in mice housed individually in metabolism cages. Physiol Res, 2009. 58(1): p. 69-75 Category: Physiology Impact Factor: 1.653 Ranking: 51/74 [ANT,PHY] 104. Hoy, A.J., A.E. Brandon, N. Turner, M.J. Watt, C.R. Bruce, G.J. Cooney, and E.W. Kraegen, Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt or AS160 phosphorylation. Am J Physiol Endocrinol Metab, 2009. 297(1): p. E67-E75 Category: Physiology Impact Factor: 3.855 Ranking: 14/74 [PHY] 105. Huijsman, E., C. van de Par, C. Economou, C. van der Poel, G.S. Lynch, G. Schoiswohl, G. Haemmerle, R. Zechner, and M.J. Watt, Adipose triacylglycerol lipase deletion alters whole body energy metabolism and impairs exercise performance in mice. Am J Physiol Endocrinol Metab, 2009. 297(2): p. E505-E513 Category: Physiology Impact Factor: 3.855 Ranking: 14/74 [PHY] 106. Huynh, J., W.G. Thomas, M.I. Aguilar, and L. Pattenden, REVIEW: Role of helix 8 in G protein-coupled receptors based on structure–function studies on the type 1 angiotensin receptor. Mol Cell Endo, 2009. 302(2): p. 118-127 Category: Cell Biology Impact Factor: 3.611 Ranking: 66/157 [BCH] 107. Ijiri, H., F. Coulibaly, G. Nishimura, D. Nakai, E. Chiu, C. Takenaka, K. Ikeda, H. Nakazawa, N. Hamada, E. Kotani, P. Metcalf, S. Kawamata, and H. Mori, Structurebased targeting of bioactive proteins into cypovirus polyhedra and application to immobilized cytokines for mammalian cell culture. Biomaterials, 2009. 30(26): p. 4297-4308 Category: Engineering, Biomedical Impact Factor: 6.646 Ranking: 2/51 [BCH] -11- 108. Iqbal, J., O. Latchoumanin, I.P. Sari, R.J. Lang, H.A. Coleman, H.C. Parkington, and I.J. Clarke, Estradiol-17{beta} inhibits GnRH-induced Ca2+ in gonadotropes to regulate negative feedback on LH release. Endocrinology, 2009. EPub Category: Endocrinology & Metabolism Impact Factor: 4.945 Ranking: 20/93 [PHY] 109. Ireland, Z., H. Dickinson, B. Fleiss, L.C. Hutton, and D.W. Walker, Behavioural Effects of Near-Term Acute Fetal Hypoxia in a Small Precocial Animal, the Spiny Mouse (Acomys cahirinus). Neonatology, 2009. 97(1): p. 45-51 Category: Pediatrics Impact Factor: 1.920 Ranking: 26/86 [PHY] 110. 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