As you are aware the content of MOPART corresponds to a critical need of efficient and robust optimisation methods and tools for aircraft and engine designers and manufacturers. Here are the key parameters of the CA : the main framework includes multi objective and multi disciplinary optimization problems to be tackled cooperatively on a real or virtual communication and software platform. Validation and verification methods and guidelines of multiphysics analysers are also part of the CA since validation for optimization and validation for analysis are strongly nested procedures. Title : Promoting Cooperative Multidisciplinary Design Optimization in Aeronautics (PROMOPART) Duration : 18 months A.The key ingredients of the CA : (i) o Optimization methods and tools for strongly coupled disciplines; (ii) o Verification and Validation methods and guidelines for optimization and analysis ; (iii) o Integrated Software Platform (sharing tools and working together) ; Participation in designing an integrated platform for numerical simulation and visualization of blood vessels and blood circulation under specific set of parameters characterizing in flight cabin conditions. Integrated Simulation platform in order to involve Modeling of Cardiovascular System coupling with dynamic multibody systems, Network models, inflight Aircraft Cabin Environments. (iv) o E-Communication System; (v) o Design; (vi) o Database; including historical and simulated data on interaction disease/inflight parameters. Analysis of Data of exsisting consultation on the Possible Effects on Health, Comfort and Safety of Aircraft Cabin Environments. (vii) o Mesh generators; (viii) o CADCAM tools (ix) o Parameterization Identification of main physical, design, biological parameter in order to Perform suitable case studies control for aircraft cabin health. Identification of reliable scale for simulation of cardiovascular system and for Dynamics of body of aircraft passengers. Parametrization of design variables with respect Health Effects in Aircraft Cabin Environment. (x) o Turbulent flows (LES,?) B.The interfaces of the key ingredients to be studied : xi) o Cadcam systems / discretized environment ; x) o Multi-physics enviroment analysers ; Coupling of biophysical parameters related to tissue of blood vessels, blood circulation and geometric/physical parameters in the aircraft cabin during flight . xi) o Evolutionary/deterministic optimizers ; Implementation of stochastic methods of optimization based on multiagent systems such as ANT SYSTEMS (Ant Colony Optimizers). In contrast with classical methods ACO's the stochastic component provides better exploration of the space of solutions. Agents evolve stochastically , strongly coupled with a chemoattractant underlying field. Develop algorithms and theory necessary to consider parallel computer for ant systems simulation. xii) o Optimizers and solvers ; Shape optimization methods are needed for optimizing seat and cabin shape to reduce risk of cardiovascular diseases. Wavelet , multiresolution and multilevel methods for optimal shape design and for large scale optimization problems. xiii) o Multi-disciplinary applications A multidisciplinary approach is strongly necessary ( including BiomedicinePhysiology-Mathematical modelling - Simulation and Visualization toolsEngineering - Statistics) for coordinating Statistics of available and designed data Modelling and analysis of the rheological blood circulation systems Optimization and control of environmental parameters in aircraft cabins with respect to risk reduction Clinical follow up studies xiv) o Others C.The multidisciplinary targeted applications are : xv) o Noise prediction and Reduction ; xvi) o Flutter prediction and Reduction ; xvii) o High Lift Devices ; xviii) o Thermal Flows ; xix) o Reduction of risk with blood circulation systems in civil aircraft cabins ; In recent times there is more and more concern about quality of life of passengers on board of commercial flights. A general alarm has been launched among commercial airline companies due to recent cases of death from DVT. A careful cause - effect analysis in terms of the risk of a diseases such as DVT or others is needed for prevention purposes in ergonomic design of aircraft cabins in terms of geometry and general environmental conditions such as pressure, temperature etc. xx) o Others The studies envisaged are prospective only and target means and tools have been chosen in order to demonstrate - the benefit of human and numerical cooperative work for future multidisciplinary design optimization (MDO) to reduce design & manufacturing cycle ; - the benefit of the integration platform prototype as a sustainable european plateau ; - the master of interfaced disciplines with innovative seamless methods.