First French-Argentine First French-Argentine Immunology Congress LVIII Reunión Anual de la Sociedad Argentina de Inmunología XIII Jornada Científica del Grupo Rioplatense de Citometría de Flujo 3º Jornadas Argentinas de Inmunodeficiencias Primarias (SAP) Buenos Aires, Argentina 2nd-5th November, 2010 www.faic-cooperation.com www.inmunologia.org.ar November 2nd School of Medicine, Buenos Aires University, Aula Magna (Main Floor) 17:30 - 20:00 18:30 - 19:30 19:30 - 20:30 20:30 - 21:00 21:00 - 22:00 REGISTRATION Opening Ceremony FAIC Organizers: E. Chuluyan, E. Piaggio and J. Cohen Decano Facultad de Medicina: Prof. Alfredo Buzzi; Rector UBA: Dr. Ruben Hallu; Ministro de Salud CABA: Dr. Jorge Lemus; Ministro de Educación: Prof. Alberto Estanislao Sileoni; Ministro de Ciencia y Tecnologia e Innovacion Productiva: Prof. Dr. Lino Barañao; Embajador de Francia: Jean-Pierre Asvazadourian Opening Conference - Chairman: J. Wietzerbin Sebastian Amigorena: "Antigen presentation and T cell activation by dendritic cells" Cultural Activity Welcome cocktail November 3rd PALAIS ROUGE (Jerónimo Salguero 1431, Buenos Aires) 8 :00 – 19 :00 Registration Session Room Pigalle, 2nd Floor AUTOIMMUNITY - Chairmen: O. Boyer, V. Rivero 08:30 – 09:00 L. Chatenoud Restoration of self-tolerance in experimental and clinical autoimmunity' 09:00 –09:30 A. Gruppi : Role of Fc-gamma RIIB in the survival of B cells subsets and its association with autoimmunity. 09:30 - 10:00 BIOTECH - Chairmen: A. Diaz, F. Goldbaum Romikin/Elea – Arg, Remy Urbain LFB, France 10:00 – 10:30 Coffee break (Doree Room, 1st Floor) 10:30 – 11:20 4 Selected abstract (8 min presentation and 4 min discussion) 11:20 – 11:50 R. Liblau : Animal models of CNS autoimmunity: what have we learned? 11:50 – 12:20 J. Lafaille : Regulatory T cells that control autoimmune diseases: antigen specificity and timing of protection 12:20 - 14:30 Room Matisse B, Ground Floor Symposiums, oral presentations and minicourses MODULE V: Immune Deficiencies Flow cytometry in diagnosis, treatment and follow-up of Primary Immune Deficiencies (J. Rossi, Hospital Garrahan) MODULE VI: FRET and BRET Methods to Study Protein Interactions in Immunology: FRET and BRET (J. Iovanna, N. Ducetti, INSERM, Marseille, France) Rodin Room, 2nd Floor : Immunology I (Posters) Session IMMUN0DEFICIENCY - Chairmen: F. Rieux Laucat, L. Bezrodnik Neuroimmunology: Chairmen: Dr. E. Arzt 14:30 – 15:00 S. Rosenweig: Genetic susceptibility to fulminant A Hepatitis 15:00 – 15:30 J. Bustamante NEMO: poli-ubiquitinization defects Symposium : D. Verthelyi TLRs as therapeutic targets in CNS inflammation and infection C. Perez Leirós 15:30 –16:00 BOITECH - Chairmen: P. Maffia Lic. Marcelo Arguelles (BioSidus – Arg). France 16:00 - 16:30 Coffee break (Doree Room 1st Floor) 16:30 – 17:20 4 Selected abstract (8 min presentation and 6 min discussion) 17:20 – 17:50 F. Rieux Laucat : “Genetic bases of Primary Immunodeficiencies accompanied with auto-immune manifestations” 17:50 – 18:30 Critical Topics: A. Ginaca: “Searching Primary Complement Immunodeficiency ” S. Danielian: “Selecting THE gene in PIDs: a variety of disorders but overlapping characteristics" 18 :30 -19 :30 Immunology II: Oral Presentations Leonardo Satz Conference – Chairman: Prof. L. Fainboim Alain Fischer: Primary Immuno-Deficiencies: Pathological models to study the human immune system development Autoimmunity and Immunotherapy : Chairmen : Dr. Clelia Riera M. Perone : Autoimmune Diabetes G. Prat Gay: Molecular basis for the recognition of DNA by auto-antibodies. Immunology III: Oral Presentations November 4th PALAIS ROUGE (Jerónimo Salguero 1431, Buenos Aires) Registration 8 :00 – 19 :00 Room Pigalle, 2nd floor Session ALLERGY-INFLAMMATION - Chairmen: A. Magnan, G. Docena 08:30 – 09:00 A. Larregina: Regulatory role of pro-inflammatory neuropeptides in cutaneous T helper immune response: contact and atopic dermatitis immunity 9:00 –09:30 N. Glaichenhaus Breast milk immune complexes are potent inducers of oral tolerance in neonates and prevent asthma development. 9:30 - 10:00 BIOTECH – Chairmen : F. Chirdo Amega Biotech, Argentina, Stallergene, Philippe Moingeon : Sublingual vaccines for respiratory allergies. 10:00 – 10:30 2 Selected abstract (8 min presentation and 4 min discussion) 10:50 – 11:20 J-M Sallenave 11:20 – 11:50 A. Tsicopoulos: Chemokines in allergic diseases, beyond migratory functions 12:30 - 14:30 INFECTIOUS DISEASES - Chairmen: C. Leclerc, O. Bottasso 14:30 – 15:00 A. Epstein: How to defeat immunity. A virologist perspective 15:30 –16:00 SAP Infections: Chairman: V. Garcia H. Lujan: Disruption of antigenic variation is crucial for effective parasite vaccine M. Gherardi: Relevance of HIV-1 subtype specific immunity in the development of vaccines for Argentina S. Di Genaro 8:30- 8:45 Welcome by L. Bezrodnik 8:45- 9:30 S. Amigorena: Fagosome Functions. Coordinator: M. Zelazko ; Secretary: I. Uriarte 9.45-10:30 A. Fischer : Gene therapy of primary immunodeficiencies Coordinator: S. Danielian ; Secretary: A. Lozano 11:00-12:45 Round Table: Update in Chronic Granulomatous Disease (CGD) Coordinator: H. Díaz; Secretary: J. Orellana S. Rosenzweig: CGD in 2010. A. Condino: CGDE in tuberculosis. L. Bezrodnik: Intestinal disease and B lymphocytes commitment Critical Topics: A. Trevani: Matrix extracellular DNA is a relevant proinflammatory component of bacterial biofilms, V. del Pino Rodin Room, 2nd Floor Immunology IV (Posters) Session 15:00 – 15:30 Room Matisse B (Ground floor) Coffee Break (Doree Room 1st Floor) 10:30 – 10:50 11:50 – 12:30 Room Matisse A Ground floor J.C. Sirard: Mucosal detection of microorganisms: outside or inside taste different BIOTECH – Chairmen : N. Amiano Inmunova - ArgFrance 16:00 - 16:30 16:30 - 17:00 E. Zúñiga Immune Dysregulation During Chronic Viral Infection 17:00 – 17:40 Critical Topics: V. Garcia: Cytokine production by signaling proteins during immune response against M. tuberculosis, M. del C. Sassiain: Influence of Mycobacterium tuberculosis genotypes on the host immune response 17:40 –18:00 2 Selected abstract (7 min presentation and 3 min discussion) 18:00 – 18:30 Up-date on Grant Applications for France-Argentine Collaborations 18 :30 – 19 :30 Assembly of the SAI Immunology V: Oral presentation 14:30-16:00 Coffee Break (Doree Room 1st Floor) 4 Selected abstract (8 min presentation and 6 min 16:30-17:15 discussion) 17:30-18:15 Oral Presentations J. Bustamante: Mendelian susceptibility to mycobacterial diseases. Coordinator: N. Pérez; Secretary: A. Lozano F. Rieux-Laucat : Impact of somatic genetic events in Autoimmune lymphoproliferative syndrome. Coordinator: C. Riganti; Secretary: G. Belardinelli Day 5, November PALAIS ROUGE (Jerónimo Salguero 1431, Buenos Aires) Registration 8 :00 – 19 :00 Room Pigalle, 2nd Floor Session 08:30 – 09:00 9:00 –09:30 09:30 - 10:00 CANCER - Chairmen: A. Bensussan, N. Zwirner J. F. Eliaou: Inflammation and Cancer: a role for IL-17 D. Klatzmann: Cancer immunosurveillance or no cancer immunosurveillance? BIOTECH – Chairmen: A. Díaz, R. Diez L. Alonso: A cost-effective prophylactic HPV vaccine for massive application, XBIO, SA, Arg; Ch. De Romeuf, LFB: EMABLING® antibodies: from fetomaternal alloimmunisation prophylaxis to chronic lymphocytic leukaemia therapy. 11:20 – 11:50 11:50 – 12:30 12:30 - 14:30 Session 14:30 – 15:00 15:00 – 15:30 15:30 –16:00 16:00 - 16:30 16:30 – 17:00 17:00 – 18:00 18:00 – 19:15 19 :30 – 20 :30 22 :00 Room Matisse B Ground Floor SAP 08:3010:00 Round Table: Primary Immunodeficiency Patients Recording. Coordinator: D. Di Giovanni; Secretary: G. Seminario A. Condino: LASID Recording in 2010. A. Gómez Raccio: One Center reccording in Buenos Aires City Three Centers experience: M. Galicchio: Rosario; J. Orellana: Córdoba; L. Regairaz: La Plata Coffee Break (Doree Room 1st Floor) 10:00 – 10:30 10:30 – 11:20 Room Matisse A Ground Floor Tolerance – Chairmen: L. Lustig, T. Gentile L. Arruvito: T regs. V. Guazzone J.L. Touraine : Immunological tolerance to both donor and host, and "allo+x" recognition of antigen 4 Selected abstract (8 min presentation and 4 min discussion) Immunology VI: Oral Presentations Dendritic Cells- Chairman: J. 10.30Geffner. 11.45 A. Morelli; C. Cuturi; C. LeClerc.: Antigen delivery to MGL+ CD103- dermal dendritic cells favors Th2 responses and Critical Topics: Mariana Maccioni + Stella Maris Ranuncolo 11:45the induction of potent anti12 :15 tumoral antibody responses, in the absence of adjuvant Rodin Room 2nd Floor Immunology VII and SAP (Posters) TRANSPLANTATION - Chairmen: Ignacio Anegon, Martin Rumbo Perspectives in BiotechnologyChairman: M. Palermo E. Carrosela: Immunological function of HLA-G molecule. M.L. Cerutti: Oncoprotein based immunotherapy for HPV linked to cervical cancer S. Maury: Regulatory T-cells in allogeneic stem cell transplantation: a phase I/II D. Pardo : BIOTECH 2010, challenges clinical trial and opportunities in South America Wolf Hervé Fridman: Immune control of human tumors BIOTECH – Chairmen : A. Díaz, P. Maffia Bernard Vanhove, TcL Pharma : Developing an immunosuppression compatible with Treg function, France. Centro Hemoderivados de Córdoba, Arg Coffee Break (Doree Room 1st Floor) M. Brown: T Cell Adaptation to chronic antigen stimulation. Critical Topics: A. Toubert: "Thymic function in allogeneic stem cell transplantation",F. Cicora Leonardo Satz Award Closing Conference- Chairman: E. Charreau G. Rabinovich: Tolerogenic circuits driven by galectin-glycan lattices in the resolution of inflammation Closing Dinner Round Table: Gammaglobulin in Primary Immunodeciency patients (PIDP). Coordinator: L. Castro Zorrilla; Secretary: C. Cantisano D. Liberatore: IVIG Indications in PIDP; M. Galicchio: IVIG: Mechanisms of action D. Di Giovanni: IVIG usage impact in PIDP. Aid association for PIDP Sra. R. Pena; Secretary: D. Díaz Ballve