Quality Assurance Unit
Faculty of Pharmacy
Course Specifications
1- Basic Information:
Course code: 446
Course title: STATISTICS, DRUG
Year: 4th (New curriculum)/
SCREENING AND BIOLOGICAL
EVALUATION
Semester:4th (New
curriculum)/
No. of contact hours/week )‫)بالنسبة لمرحلة البكالوريوس‬: 2/w
Theoretical: 24 hrs
Practical: 24 hrs
2- Course Goals:
1. Develop the knowledge gained by studying and understanding the pharmacology
course and apply it for biological screening procedures of drugs.
2. Understand how to use some biological screening procedures to evaluate the
potency (biological standardization ) of newly developed active compounds either
natural or synthetic or even established drugs in comparison with existing standard
drugs.
3. Develop the knowledge to screen and biologically standardize hormonally active
compounds.
4. Learn various statistical procedures to analyze different data obtained from
biological experiments.
5. Plan , design and conduct biological researches.
6. Develop presentation skills.
7. Able to be self learner for continuous improvement of professional knowledge and
skills.
3- Intended Learning Outcomes of Course (ILOs):
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Quality Assurance Unit
Faculty of Pharmacy
a. Knowledge and
understanding
After completing the course the student should be able to:
a.1. That is relevant to biological screening basic
pharmacology and standardization of drug activities.
a.2. Various methods of biological screening of drug activities
a.3. Principles of identification and standardization methods
of pharmaceutical compounds using biological
systems.
a.4. Methods of biostatistical analysis.
a.5. Interpretion of the mathematical results of biostatistical
procedures
b. Professional and
Practical Skills
After completing the course the student should be able to:
b.1. Identify and / or standardize active substances from
different origins using biological systems .
b.2. Design appropriate biological screening and
standardization experiments.
b.3. Use basic pharmacological laboratory equipment safely
and effectively.
b.4. Explain the principles and limitations of practical
techniques.
c. Intellectual Skills After completing the course the student should be able to:
c.1.
Apply qualitative and quantitative biological methods
for QC and bioassay of raw materials as well as
pharmaceutical preparations.
c.2.
Select the appropriate methods of identifications ,
screening and standardization of active substances
from different origins.
c.3.
Retrieve and select the proper statistical procedure for a
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Quality Assurance Unit
Faculty of Pharmacy
given process.
d. General and
Transferable
c.4.
Indentify and classify the main screening procedure to
various related and complementary tests to investigate
other possible beneficial or adverse effects of agents or
new drugs.
c.5.
Present the data correctly , with tables and graphs.
c.6.
Analyze and interpret experimental data as well as
published literature.
After completing the course the student should be able to:
d.1.
Skills
Use numeracy , calculation and statistical methods as
well as information technology tools.
d.2.
Work effectively in groups.
d.3.
Practice independent learning needed for continuous
professional development.
d.4.
Adopt safety guidelines regarding animal handling.
d.5.
Implement writing and presentation skills.
d.6.
Demonstrate critical thinking problem solving and
decision making abilities.
4- Course Content:
1. Biostatistics.
2. Introduction to screening procedures.
3. Screening and bioassay of various drug groups.
4. Bioassay of hormones.
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Faculty of Pharmacy
Quality Assurance Unit
5- Teaching and Learning Methods:
1. Lectures .
2. Laboratory work.
3. Assignments .
4. Reports and posters .
5. Round case discussions.
6. Web based search assignments.
6- Student Assessment:
Methods of Assessment
Weighting
Assessment Schedule
%
Practical exam
30
7th and 14th week
Written Exam
50
15th week
Oral Exam
20
15th week
7- List of Textbooks and References:
1. Course Notes:
Departmental lecture notes
2. Essential Books (Text
Books):
Pharmacological basis of therapeutics Goodman and
3. Recommended Books:
Drug discovery and evaluation Vogel and Vogel latest
Gilman latest edition
edition
4. Periodicals, Web Sites:
Pub med and science direct
8- Required Facilities for Teaching & Learning:
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Faculty of Pharmacy
Quality Assurance Unit
1. Personal Computer (available for each staff member),
2. Power Point Displayer (Data-Show); easy available for the usual lectures and
Labs.
3. Lecture Hall
4. Computer Hall with enough devices and internet connection
5. Meeting rooms for office hours
6. Laboratories , appropriate instruments and experimental animals
9- Matrices of knowledge and skills:
Topics
Number of
weeks
Knowledge and
understanding
Professional
and Practical
Skills
Intellectual
Skills
General and
Transferable
Skills
Theor.
Pract.
1. Introduction
2
2
a1
B2,b3
c1, c2
D4
2. biostatics
5
5
A4,a5
-
C3,c5,
c6
D1,d6
3. bioassay and screening
of autonomic drugs
7
7
A1,a2 a3
B1,b4
C4
-
4. bioassay and screening
of hormones
2
2
A1, a2 ,a3
B1,b4
C4
-
5. bioassay and screening
of central nervous
system
4
4
A1,a2,a3
B1,b4
C4
D2,d5,d3
6. bioassay and screening
5
5
A1,a2,a3
B1,b4
C4
-
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Faculty of Pharmacy
Quality Assurance Unit
of cardio vascular
drugs
7. bioassay and screening
of autacoids
2
2
A1,a2,a3
B1,b4
C4
-
Knowledge and
understanding
Professional and
Practical Skills
Intellectual
Skills
General and
Transferable
Skills
A1,a2,a3,a4,a5
B1,b2
C1,c2
-
2. Laboratory work
-
B3,b4
C1,c2,c3,c4
D2,d4
3. assignments
-
-
C5,c6
-
4. laboratory activities
-
-
C3
D1,d3,D5,d6
Teaching and Learning Methods
1. lectures
Student assessment methods
Knowledge and
understanding
Professional
and Practical
Skills
Intellectual
Skills
General and
Transferable Skills
A1,a2,a3,a4,a5
B1,b2
C1,c1,c3,
c4
D1
-
B1,b2
C1,c2
D3,d4
A1,a2,a3,a4,a5
B1,b2
C1,c2,c4
-
1. written exam
2.
practical exam
3. oral exam
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Faculty of Pharmacy
Quality Assurance Unit
Course Coordinator:
Signature:
Name: Dr Engy mohamad
Head of Department:
Signature:
Name: Assistant. Prof. Dr Amany Ali
Eissa
Date: 29-11-2011
Academic year: 2010/2011
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