Department of Biochemistry Seminar Schedule 2009-2014 Tuesdays at noon Tuesday April 22ndt 2014 @ noon (3A) John Hill, PhD Senor Scientist Department of Pharmacology Amgen Title: "Drug Discover” Michael Garrett, PhD Associate Professor Department of Pharmacology University of Mississippi Medical Center Title: "Genomic Technologies at UMMC: The stuff that dreams are made of…” Tuesday December 10, 2013 @ noon (4A) Ritu Aneja, PhD Associate Professor Department of Biology, College of Arts and Sciences Georgia State University Title: "Severing the ties that bind: Centrosome declustering is a chemotherapeutic strategy of exceptional potential" Tuesday November 26, 2013 @ noon (4A) Gene “Lee” Bidwell III, PhD Assistant Professor Department of Neurology University of Mississippi Medical Center Title: "Maternally restricted therapeutic proteins for treatment of preeclampsia" Tuesday October 29, 2013 @ noon (4A) Eric George, PhD Assistant Professor Department of Physiology and Biophysics University of Mississippi Medical Center Title: "New pathogenic mechanisms in preeclampsia" Tuesday October 15, 2013 @ noon (4A) Radhika Pochampally, PhD Associate Professor Cancer Institute Department of Biochemistry University of Mississippi Medical Center Title: "Tumor supportive microRNA and cytokines in exosomal fraction of stressed Mesenchymal Stem/Stromal Cells" Tuesday October 1, 2013 @ noon (4A) Michael A. Puskarich, MD Assistant Professor Department of Emergency Medicine Adjunct Professor Department of Biochemistry University of Mississippi Medical Center Title: "Frontiers in sepsis: The riddle of the mitochondria and microcirculation" Tuesday August 20, 2013 @ 10:00 AM (3A) Eszter K. Vladar, Ph.D. Postdoctoral Researcher Department of Pathology Stanford University School of Medicine Title: "How to Make a Functional Ciliated Cell" Tuesday June 4, 2013 @ noon (3A) Martina Brueckner, MD Associate Professor Departments of Pediatrics & Genetics Yale University School of Medicine Title: "Congenital heart disease and the cilium" Tuesday May 21, 2013 @ noon (3A) John David Dignam, Ph.D. Professor Department of Biochemistry and Cancer Biology University of Toledo College of Medicine Title: "Use of Polyethylene Glycol Modifed Human Albumin in the Treatment of Hypovolemia Associated with Sepsis and Trauma" Tuesday May 14, 2013 @ noon (3A) Emily I. Chen, Ph.D. Assistant Professor Department of Pharmacological Sciences Scientific Director, Proteomics Center School of Medicine Stony Brook University Title: "TBD" Tuesday May 7, 2013 @ noon (3A) Merry L. Lindsey, Ph.D., FAHA, FAPS Director, Jackson Center for Heart Research Director, San Antonio Cardiovascular Proteomics Center Professor Department of Physiology and Biophysics University of Mississippi Medical Center Title: "Exploring the Cardiac Extracellular Matrix" Tuesday April 23, 2013 @ noon (3A) Nichola C. Garbett, Ph.D. Director of Laboratory Operations Louisville Bioscience Inc. Instructor of Medicine Department of Medicine University of Louisville Title: "Diagnostic application of plasma protein calorimetry" Tuesday April 16, 2013 @ noon (3A) Kirk A. Mykytyn, Ph.D. Associate Professor Department of Pharmacology The Ohio State University Title: "Physiology and Pathophysiology of Neuronal Primary Cilia" Tuesday April 2, 2013 @ noon (4A) José Javier Miguel-Hidalgo, Ph.D., D.M.Sc. Assistant Professor Department of Psychiatry and Human Behavior University of Mississippi Medical Center Title: "Neurochemistry of Depression and Alcoholism: Lessons from Postmortem Studies of the Human Brain" Tuesday March 19, 2013 @ noon (3A) Kounosuke Watabe, Ph.D. Professor Departments of Microbiology & Biochemistry Associate Director for Basic Science Cancer Institute University of Mississippi Medical Center Title: "Roles of microRNA and Notch signaling in brain metastasis of breast cancer" Tuesday February 19, 2013 @ noon (3A) Yin-Yuan Mo, Ph.D. Professor Department of Pharmacology and Toxicology & Cancer Institute University of Mississippi Medical Center Title: "Non-coding RNAs in cancer" Tuesday January 8, 2013 @ noon (6A) Mark E. Hatley, M.D., Ph.D. Assistant Member Solid Tumor Division, Department of Oncology St. Jude Children's Research Hospital Title: "Rhabdomyosarcoma originating outside of the muscle lineage" Tuesday December 11, 2012 @ noon (6A) Jian-Xiong Chen, M.D. FAHA Associate Professor Department of Pharmacology and Toxicology University of Mississippi Medical Center Title: "Mechanisms of diabetes-induced impairment of angiogenesis" Tuesday November 13, 2012 @ noon (3A) James A. Stewart, Jr., Ph.D. Assistant Professor Department of Biological Sciences Mississippi State University Title: "AGE/RAGE Axis in Type 2 Diabetes" Thursday November 1, 2012 @ 11:00 am (6A) David L. Bain, Ph.D. Associate Professor and Director, Pharmaceutical Sciences Graduate Program Department of Pharmaceutical Sciences University of Colorado Anschutz Medical Campus Title: "Toward a Quantitative Understanding of the Human Steroid Receptors: The Role of Energetics" Thursday May 10, 2012 @ 11:00 am (4A) Matthew E. Burow, Ph.D. Associate Professor Department of Medicine Tulane University School of Medicine Title: "Glyceollins - Novel Selective Estrogen Receptor Modulators identified from stressed soy" Thursday April 19, 2012 @ 11:00 am (4A) Istvan Arany, Ph.D., C.Sc. Professor Department of Pediatrics University of Mississippi Medical Center Title: "Signaling Pathways Involved in Adverse Effects of Chronic Nicotine Exposure on Kidney Injury" Thursday March 29, 2012 @ 11:00 am (3A) Azeddine Atfi, PhD Director, Tumor Cell Biology Program Cancer Institute Professor Department of Biochemistry University of Mississippi Medical Center Title: "Mechanisms of Wnt signaling amplification by the homeodomain protein TGIF" Thursday March 1, 2012 @ 11:00 am (3A) Bruce Littlefield, PhD Distinguished Scientist, Oncology Eisai, Inc. Title: "Discovery and Development of Halichondrin B Macrocyclic Ketone Analog Eribulin (Halaven®) as a New Drug for Late-Stage Metastatic Breast Cancer Patients " Thursday February 23, 2012 @ 11:00 am (3A) Radhika Pochampally, PhD Associate Professor Cancer Institute Department of Biochemistry University of Mississippi Medical Center Title: "MicroRNA-mediated Mesenchymal Stromal Cell Survival in Breast Cancers" Thursday February 2, 2012 @ 11:00 am (3A) Jonathan Hosler, PhD Professor Department of Biochemistry University of Mississippi Medical Center Title: "Pathways for Copper in Cytochrome Oxidase Assembly" Thursday December 4, 2011 @ 4:00 pm (CW308) Runzhao Li, MD Assistant Professor Department of Hematology and Medical Oncology Winship Cancer Institute Emory University School of Medicine Title: "Paradoxes of the Function and Variant forms of EAPII/TTRAP/TDP2 in Human Tumors" Thursday November 10, 2011 @ 4:00 pm (CW106) Seongjin Seo, Ph.D. Assistant Professor Department of Ophthalmology and Visual Sciences University of Iowa Carver College of Medicine Title: "The Molecular Pathophysiology of Bardet-Biedl Syndrome: Biochemical, Cell Biological, and Genetic Approaches" Thursday October 27, 2011 @ 4:00 pm (CW106) Rakesh K. Singh, Ph.D. Postdoctoral Research Associate Department of Biomedical Sciences College of Medicine Florida State University Title: "Histone Proteolysis and Its Role in Genome Maintenance" Thursday October 20, 2011 @ 11:00 am (CW308) Istvan Arany, Ph.D., C.Sc. Professor Department of Pediatrics University of Mississippi Medical Center Title: "Signaling pathways involved in chronic nicotine exposure-mediated kidney injury" Thursday October 13, 2011 @ 4:00 pm (CW106) Daitoku Sakamuro, Ph.D. Assistant Professor Department of Pathology Stanley S. Scott Cancer Center LSU Health Sciences Center Title: "Oncogenic c-MYC, Genomic Instability & DNA Damage Resistance" Thursday September 29, 2011 @ 4:00 pm (CW308) Maureen Wirschell, Ph.D. Research Assistant Professor Department of Cell Biology Emory University School of Medicine Title: " The Essential Cilium: Assembly, Targeting and Regulation of the Ciliary Dynein Motors" Thursday September 8, 2011 @ 4:00 pm (CW308) John P. Hagan, Ph.D. Postdoctoral Research Fellow Department of Hematology and Oncology Children’s Hospital Boston Title: "MicroRNAs: Medulloblastoma and Their Regulation by Lin28/Zcchc11" Thursday August 18, 2011 @ 11:00 am (CW308) James G. Wilson, M.D. Director Clinical and Population Studies Professor Department of Physiology and Biophysics University of Mississippi Medical Center Title: "A high resolution recombination map of the human genome, and new insights into mechanisms of recombination" Thursday June 16, 2011 @ 11:00 am Jia (Joe) L. Zhuo, M.D., Ph.D. Professor Departments of Pharmacology & Toxicology and Medicine University of Mississippi Medical Center Title: " Intracrine/intracellular angiotensin II: a new paradigm in cardiovascular and renal regulation" Thursday May 12, 2011 @ 11:00 am A. Clay Clark, Ph.D. Professor Department of Molecular and Structural Biochemistry North Carolina State University Title: "Allosteric control of caspases as a strategy to kill cells" Thursday April 14, 2011 @ 11:00 am Michael D. Hebert, PhD Professor Department of Biochemistry University of Mississippi Medical Center Title: "The Cajal body: What have we learned in the last 108 years?" Thursday March 10, 2011 @ 11:00 am Wael M. Elshamy, PhD Associate Professor Director, Molecular Cancer Therapeutics Program Cancer Institute Department of Biochemistry University of Mississippi Medical Center Title: “Inhibiting breast cancer metastasis through suppressing Geminin and/or its aneuploidy inducing pathways” Thursday March 3, 2011 @ 11:00 am David T. Brown, PhD Professor Department of Biochemistry University of Mississippi Medical Center Title: "The role of linker histone isotypes in chromatin structure" Thursday February 24, 2011 @ 11:00 am Paul R.S. Baker, PhD Assistant Professor Department of Pharmacology University of Pittsburgh Title: “Biogeneration and Anti-Inflammatory Properties of Nitrated Fatty Acids” Thursday February 3, 2011 @ 11:00 am Damian G. Romero, PhD Assistant Professor Department of Biochemistry University of Mississippi Medical Center Title: "Regulator of G-protein signaling 22 and breast cancer cell proliferation" Thursday January13, 2011 @ 11:00 am Victor L. Davidson, PhD Professor Department of Biochemistry University of Mississippi Medical Center Title: " Remote enzyme microsurgery: How to generate powerful oxidants and specifically modify proteins without causing oxidative stress" Thursday December 9, 2010 @ 11:00 am Luis A. Martinez, PhD Associate Professor Department of Biochemistry University of Mississippi Medical Center Title: "Regulation of E2F3 by Chemotherapy" Thursday November 18, 2010 @ 11:00 am John J. “Jack” Correia, PhD Professor Department of Biochemistry University of Mississippi Medical Center Title: "Progress on the Biophysics of Anti-Cancer Drugs" Wednesday November 10, 2010 @11:00 am Tomoo Iwakuma, MD, PhD Assistant Professor Department of Genetics Louisiana State University Health Sciences Center Title: TBD October 21, 2010 @11:00 am Anait S. Levenson, MD, PhD Associate Professor Department of Pathology Cancer Institute University of Mississippi Medical Center Title: “Epigenetic Mechanisms of Anticancer Activity of Resveratrol in Prostate Cancer: the Role of MTA1” September 23, 2010 @11:00 am - CANCELLED Paul R.S. Baker, PhD Assistant Professor Department of Pharmacology University of Pittsburgh Title: “Biogeneration and anti-Inflammatory Properties of Nitrated Fatty Acids” September 16, 2010 @11:00 am John E. Hall, PhD Arthur C. Guyton Chair & Professor Associate Vice Chancellor for Research Department of Physiology and Biophysics University of Mississippi Medical Center Title: “Obesity-induced hypertension: role of the sympathetic nervous system, leptin and melanocortins” August 26, 2010 @11:00 am Chindo Hicks, PhD Associate Professor Associate Director, Bioinformatics Center of Biostatistics & Bioinformatics Director, Cancer Bioinformatics Cancer Institute University of Mississippi Medical Center Title: “Elucidating the Molecular Signature of the Notch Signaling Pathway in Breast Cancer” July 29, 2010 @11:00 am Christine Maric, PhD, FAHA, FASN Associate Professor Department of Physiology and Biophysics University of Mississippi Medical Center Title: “Role of sex steroids in diabetic renal disease” July 8, 2010 @4:00 pm Felix Kratz, PhD Head, Macromolecular Prodrugs Tumor Biology Center (Freiburg, Germany) Title: “Albumin, a versatile drug carrier with increasing clinical application” June 24, 2010 @4:00 pm George W. Booz, PhD, FAHA Associate Professor Department of Pharmacology and Toxicology University of Mississippi Medical Center Title: “Uncovering the Versatility of STAT3 in Endothelial Cells” May 27, 2010 @4:00 pm D. Ashley Robinson, PhD Associate Professor Department of Microbiology University of Mississippi Medical Center Title: “MRSA Evolution in High Resolution” April 22, 2010 @4:00 pm – CANCELLED DUE TO VOLCANIC ASH Felix Kratz, PhD Head, Macromolecular Prodrugs Tumor Biology Center (Freiburg, Germany) Title: “Albumin, a versatile drug carrier carrier with increasing clinical application” March 25, 2010 @4:00 pm Lucio Miele, MD, PhD Ergon Professor of Medicine and Pharmacology Director, University of Mississippi Cancer Institute University of Mississippi Medical Center Title: “Notch signaling in breast cancer” January 28, 2010 @4:00 pm Guri Tzivion, PhD Associate Professor Cancer Institute & Department of Biochemistry University of Mississippi Medical Center Title: “AKT-FOXO and Nicotinamidase-sirtuin pathways in regulation of cancer and longevity” December 3, 2009 @4:00 pm Wolfgang H. Kramer, PhD Associate Professor of Chemistry and Biochemistry Millsaps College Title: “Potential Photodynamic Therapy Agents: Synthesis, Photophysical Properties and DNA Interactions of Nitrogen Onium Salts” November 19, 2009 @4:00 pm Cheng-Xin Gong, MD Head, Laboratory of Brain Metabolism New York State Institute for Basic Research in Developmental Disabilities Staten Island, New York Title: “Diabetes Increases the Risk for Alzheimer Disease- Mechanism Studies” October 15, 2009 @4:00 pm Ruisheng Liu, MD, PhD Assistant Professor Department of Physiology and Biophysics Division of Nephrology, Department of Medicine University of Mississippi Medical Center Title: “Regulation of macula densa neuronal nitric oxide synthase (nNOS)” September 17, 2009 @4:00 pm Elise P. Gomez-Sanchez, DVM, PhD Professor of Medicine Division of Endocrinology, University of Mississippi Medical Center Senior Research Physiologist Jackson VA Medical Center Title: “MR Selectivity: Tying down a Promiscuous Receptor” August 20, 2009 @4:00 pm JunMing Wang, PhD Assistant Professor Department of Pathology, University of Mississippi Medical Center Title: “Gonadal Hormone Receptors and Alzheimer’s Disease Risk Factors” June 18, 2009 @4:00 pm David Stec, PhD Assistant Professor Department of Physiology and Biophysics University of Mississippi Medical Center Title: “Kidney Heme Oxygenase and Hypertension”