Plastic surgery Definition: is branch of surgery that is concerned with remold, repair and restore body parts especially by transfer of tissues. Plastic as adjective mean capable of being shaped or formed. Divided into 2 parts: 1. Aesthetic or cosmetic surgery: which performed to reshape normal structure of body to improve the patient appearance e.g.rhinoplasty, face lift. 2. Reconstructive surgery: which is done for these who have congenital deformities e.g. cleft lip and palate, or those who have acquired deformities as result f infection, accident, burn. Anatomy of skin: skin is largest organ in body ranging from 0.22 m² in new born to more than 2m² in the adult. It provided barrier to invasion by microorganism, regulate the exchange of heat with environment, provided surface for vitamin D synthesis by U.V. light. It consists of epidermis and dermis. Epidermis: is the outer layer composed of keratinized stratified squamous epithelium, it divided into: Stratum germinatirum: which rest on dermis and generate the cell of stratum corneum. Stratum corneum: This is the desquamating dead superficial layer. Dermis: which is 20 times thicker than epidermis, it consists of non-cellular connective tissues (collagen and elastic fibers) and ground substances. It divided into: Upper papillary dermis (thin). Lower reticular dermis (thick) which extended form papillary dermis to subcutaneous tissues. Dermis contained sweat gland, blood vessels, lymphatics and pilosebaceous units. Subcutaneous layer: the skin is connected to the underlying bone and deep fascia by layer of areolar tissues that varies in thickness, it prominent in palm and sole, and absent in eyelid. 1 Blood supply: 1. Major vessels: deep to muscle (musculocutaneous) perforators which pass perpendicular through the muscle and deep fascia dermosubdermal plexus which supply the skin. 2. Direct cutaneous artery: superficial to muscles then dermosubdermal plexus. Wounds: is the disruption of unity or breech in surface epithelium. In primitive animals respond to this by mitosis, selected part in our body still have this ability e.g. liver, intestinal mucosa. Phases of wound healing: 1. inflammatory phases: begin at time of injury and last 2-3 days, begin with vasoconstriction to achieved hemostasis ,then vasodilatation with infiltration of neutrophils,monocytes and limited number of lymphocytes 2. Proliferative phase: begin around day 3 and last through week during which collagen synthesis and epithelization occur. 3. Remolding phase: during which increase in collagen production and breakdown, continuous for 6 month-1 year. Wound strength increase as collagen reorganized and vascularity decrease. Ladder of reconstruction: By secondary intention→direct closure→skin graft→local flap→distance Flap→free flap. Secondary intention: mostly used for small wound, by leaving wound heal by itself without surgical intervention, apart from local wound care. It depends on epithelization an contraction provided by myoblast. Direct closure: most preferable method, because it use the same skin of area with same colour and quality. it involved approximating the two end of 2 the wound by suturing. Usually done to wound with straight, clean edge, such as simple cut. Closing in such method depends on area of defect and availability of surrounding tissues. Principles of wound closure: 1. When the wound is clean, incised wound as seen in surgical wound or clear cut wound, direct closure achieved y approximation its edge without tension. 2. When the wound is lacerated, with irregular edge and contaminated, direct approximation should not done unless the wound is irrigated and debrided. Debridment: involves the excision of all devitalized, contaminated tissues and foreign body. Irrigation: involves washing the wound by copious amount of saline and ringer lactate. Method of debridment: Mechanical: This involved sharp or blunt excision of dead tissues. Gauze: repetitive application of moistened gauze which desiccates and gradually removed necrotic debris from the wound. Chemical: topical enzyme application which digests devitalized tissues. 3. When handling the tissues during closure we should avoiding excessive retraction and pressure on wound, irrigation and moist pack should be used to prevent wound desiccation. 4. aseptic technique: by strict using aseptic measurement such as hand scrubbing, using of sterile instrument, and clean operative site, and hair shaving 5. hemostasis: as bleeding can cause ischemia and hematoma formation which can lead to infection which affect normal wound healing.hemostasis can achieved by: Topical application of adrenaline. Electrocautery. Large vessels can be clamped or suture. Topical hemostatic e.g. fibrin glue. 6. antibiotics: which indicated for the fallowing: 3 Acute wound with surrounding cellulitis with gross contaminated. Human or animal bit. Immunosuppressed or diabetic patient. Vulvular heart disease to prevent endocarditis. Most soft tissues infection caused by gram (+) organism e.g. (staph., strept.).Usually we begin with broad spectrum antibiotics such as cephalosporin, and more specific therapy directed by bacterial culture and sensivity. Closure methods: 1. 2. 3. 4. Simple interrupted suture. Horizontal and vertical mattress. Subcuticular continuous suture. Continuous running suture. Closure materials: 1. Suture materials: This divided to natural and synthetic materials or to absorbable or non-absorbable. 2. Staples: which more rapid than sutures and create minimum reaction. 3. Surgical tapes: either alone or with other suture materials e.g. steristrip. 4. Biological or synthetic materials e.g. Cynoacrylate. Direct wound closure either: Primary closure which mean wound closed surgically soon after creation. Delayed primary closures which mean wound remain open for days before closure to reduce risk of infection in contamination wound. Flap: Segment of tissue contained network of blood vessels at the base of flap. Flap can classify according to the fallowing: 4 1. according to blood supply: Axial flap: which has direct cutaneous vessels lying above the muscle, it could be: a-peninsular axial flap which keep both skin and vessels intact. b-island flap in which the skin cut and keeps vessels. Random flap: which depend on musculocutaneous artery pass deep to the muscle and send perforator to base of flap. 2. According to method of transfer: Rotational flap: flap that rotate around pivot point, its semicircular flap. Transposition flap: triangular flap that rotate on pivot point, the donor site can be either closed directly or if not possible covered by skin graft. Advancement flap: it moved primarily in straight line from donor site to recipient site. There are various advancement flap like single pedicle advancement flap, bipedicle advancement flap and V-Y advancement flap. Interpolation flap: in which the donor site is separated from recipient site by pedicle of flap, so should pass above or beneath tissue to reach the recipient area. 3. According to its contents: Cutaneous Fasciocutaneous. Musculocutaneous. Osteomusculocutaneous. Omental. 4. According to proximity to defect. Local flap: flap has side of defect. Regional flap: flap not immediate adjacent to defect e.g. paramedian forehead flaps. Distance flap: not near to defect e.g. groin flap. Free flap: which mean free tissue transfer with its own blood supply and anastomosis is done with recipient site by microvascular surgery. 5 5. According to site of donation: Groin flap which supply by superficial circumflex iliac artery. Deltopectoral flap which supply by internal mammary artery. Indication of skin flap: Wound with poor vascularity. Full thickness defect of ear, check,nose. Padding of body prominence e.g. patient with bed sore. Muscle flap as motor unit. Control of infection since have good blood supply. Factors which lead to flap necrosis: Hematoma collection under flap. Tight dressing. Tight sutures. Pressure from position. Kinking of flap or pedicle. Cool ambient. Nicotine ,caffeine or other vsconstrictive agents Technical error especially from free tissue transfer. 6