CALENDAR AND THEMATIC PLAN of lectures of “Organic chemistry ” for the 2-d Year students of the Pharmaceutical Faculty (Autumn semester of 2013/2014 educational year) № 1 2 3 4 5 1. 2 3 4 Theme of lecture Module 1. Nomenclature, classification, methods of identification and purification of the organic compounds. Reactivity of the hydrocarbons. Introduction to the organic chemistry. Chemical bond and atoms interaction in the organic compounds. Hours Date 2 06.09 Methods of the identification of the organic compounds. Spatial (stereo) structure of the organic compounds Classification of the organic reactions and reagents. Saturated hydrocarbons. Unsaturated hydrocarbons Aromatic compounds Total hours Module 2. Halogen-, oxygen-, sulfur- and nitrogencontaining organic compounds Halogen-derivatives of the hydrocarbons. Mechanisms of the nucleophilic substitution and elimination. Hydroxy derivatives of hydrocarbons and thio-analogs (alcohols, thioles, phenols) Amines. Acidic and basic properties of organic compounds. Nitrogen-containing organic compounds (nitro-, diazo-, azocompounds, azodyes ) Total hours 2 20.09 2 04.10 2 2 10 18.10 01.11 2 15.11 2 29.11 2 13.12 2 27.12 Head of pharmaceutical, organic and bioorganic chemistry chair, Academician 8 B.S. Zimenkovsky CALENDAR AND THEMATIC PLAN of practical works of “Organic chemistry ” for the 2-d Year students of the Pharmaceutical Faculty (Autumn semester of 2013/2014 educational year) № 1. 2 3 4 5 6 7 8 9 1. 2 3 4 5 6 7 Theme Module 1. Nomenclature, classification, methods of identification and purification of the organic compounds. Reactivity of the hydrocarbons. Introduction. Classification, nomenclature, and structural isomerism of the organic compounds. Types of the chemical bonds and atoms interactions in the molecules of the organic compounds. Laboratorial equipments. Methods of the purification of the organic compounds. Determination of the physic-chemical constants of the organic compounds. Spatial structure of the biologically active compounds Determination of the organic compounds structures. Classification of the organic reactions and reagents Saturated hydrocarbons. (Alkanes and cycloalkanes) Unsaturated hydrocarbons (Alkenes,alkynes, alkadienes) Mononuclear aromatic compounds Polynuclear aromatic compounds. Total hours Final module control Module 2. Halogen-, oxygen-, sulfur- and nitrogencontaining organic compounds Halogen-derivatives of the hydrocarbons. Mechanisms of the nucleophilic substitution and elimination. The methods of halogenation Mono alcohols, ethers. The methods of halogenation (continuation). Polyalcohols, phenols, naphtols. Thioalcohols. Amines. Acidic and basic properties of organic compounds. Nitro-compounds. The methods of nitration of the organic compounds. Diazo- and azocompounds. The methods of nitration of the organic compounds (continuation). Azo-dyes. The methods of diazotation and azo coupling. Total hours Final module control Head of pharmaceutical, organic and bioorganic chemistry chair, Academician Hours Date 5 06.09 5 13.09 5 20.09 4 4 27.09 04.10 4 5 5 4 41 4 11.10 18.10 25.10 01.11 5 15.11 5 22.11 4 4 29.11 06.12 4 13.12 4 20.12 5 31 4 27.12 B.S. Zimenkovsky 08.11 10.01 THEMATIC PLAN of out-classes works of “Organic chemistry ” for the 2-d Year students of the Pharmaceutical Faculty (Autumn semester of 2013/2014 educational year) № 1. 2 3 4 5 6 7 8 9 10 1. 2 3 4 5 6 7 8 Theme Module 1. Nomenclature, classification, methods of identification and purification of the organic compounds. Reactivity of the hydrocarbons. Physical methods of structure confirmation of organic compounds (NMR, mass-spectrometry) Types of the chemical bonds. Types of hybridization of atomic orbitals (Nitrogen, Oxygen). The main characteristics of covalent σ- and π-bonds. Methods of study and confirmation the structure of organic compounds Conformers and isomers. Newman and Fischer projections. Enantiomers and diastereomers. Mechanisms of reactions in organic chemistry. Types of chemical reactions Determination of molecular mass of organic compounds. Energy conditions of organic reactions Non-benzene aromatic systems Triphenylmethane dyes Preparation to the final module № 1 Total hours Module 2. Halogen-, oxygen-, sulfur- and nitrogencontaining organic compounds Reactivity halogen-derivatives of the hydrocarbons. Synthesis and properties of naphtoles Identification of aromatic and aliphatic amines. Structure of azo dyes Hard and soft acids and bases Red-ox reactions of different classes of the organic compounds Acidic and basic properties of organic compounds Preparation to the final module № 2 Total hours Head of pharmaceutical, organic and bioorganic chemistry chair, Academician Hours 5 5 3 5 5 3 4 5 3 6 44 4 3 3 4 3 3 4 30 B.S. Zimenkovsky