Principal Investigator (last, first, middle): BIOGRAPHICAL SKETCH NAME POSITION TITLE Margaret Gatz Professor eRA COMMONS USER NAME margat INSTITUTION AND LOCATION Rhodes College, Memphis, TN Duke University, Durham, NC Center for the Study of Aging and Human Development, Duke University Medical Center DEGREE YEAR(s) B.A. Ph.D. Postdoctoral Research Fellow 1966 1972 1972-1973 FIELD OF STUDY Psychology Clinical Psychology Gerontology A. Positions and Honors. 1973-78 University of Maryland: Assistant Professor (1973-78), Associate Professor (1978) 1979-University of Southern California: Associate Professor (1979-85), Full Professor (1985--) 1997 Distinguished Mentorship Award, Behavioral & Social Sci., Gerontological Society of America 1999 Master Mentor Award, Div. 20, Am. Psychological Assoc., Retirement Research Foundation 2000-Foreign Adjunct Professor, The Karolinska Institute, Department of Medical Epidemiology 2003-2004 Zenith Award, Alzheimer’s Association 2005 APA Committee on Aging, Award for the Advancement of Psychology and Aging 2005 Distinguished Research Achievement Award, Division 20, American Psychological Assoc. B. Selected peer-reviewed publications (last three years). Andel, R., Crowe, M., Pedersen, N.L., Mortimer, J., Crimmins, E., Johansson, B., & Gatz, M. (2005). Complexity of work and risk of Alzheimer’s disease: A population-based study of Swedish twins. J Gerontol B Psychol Sci Soc Sci, 60, 251-258 Fiske, A., Gatz, M., Aadnøy, B., & Pedersen, N.L. (2005). Assessing age of dementia onset: Validity of informant reports. Alzheimer Dis Assoc Disord, 19, 128-134. Gatz, M., Fratiglioni, L., Johansson, B., Berg, S., Mortimer, J.A., Reynolds, C.A., Fiske, A., & Pedersen, N.L.. (2005). Complete ascertainment of dementia in the Swedish Twin Registry: the HARMONY study. Neurobiol Aging, 26, 439-447. Heflin, L. H., Meyerowitz, B. E., Hall, P., Lichtenstein, P., Johansson, B., Pedersen, N. L., & Gatz, M. (2005). Cancer as a risk factor for long-term cognitive deficits and dementia. J Natl Cancer Inst, 9, 854–856. Reynolds, C. A., Turner, A., Gatz, M., & Pedersen, N. L. (2005). Comparative Rating Measures of Health and Environmental Exposures: How Well Do Twins Agree? Twin Res, 8, 113-119. Gatz, M. (2005). Educating the brain to avoid dementia: Can mental exercise prevent Alzheimer disease? PLoS Med, 2, 38-40. Rasgon, N.L., Magnusson, C., Johansson, A.L.V., Pedersen, N.L., Elman, S, & Gatz, M. (2005). Endogenous and exogenous hormone exposure and risk of cognitive impairment in Swedish twins: A preliminary study. Psychoneuroendocrinology, 30, 558-567. Fiske, A., Gatz, M., & Hannell, E. (2005). Rural suicide rates and availability of health care providers. J Community Psychol, 33, 537-543. Wirdefeldt, K., Gatz, M., Pawitan, Y., & Pedersen, N.L. (2005). Risk and protective factors for Parkinson's disease: A study in Swedish twins. Ann Neurol, 57, 27-33. Reynolds, C.A., Finkel, D., McArdle, J.J, Gatz, M., Berg, S. & Pedersen, N.L. (2005). Quantitative genetic analysis of latent growth curve models of cognitive abilities in adulthood. Dev Psychol, 41, 3-16. Heller, K., Alexander, D.B., Gatz, M., Knight, B.G., & Rose, T. (2005). Social and personal factors as predictors of earthquake preparation: The role of support provision, network discussion, negative affect, age, and education. J Appl Soc Psyc, 35, 399-422. Le Roux, H., Wetherell, J.L., & Gatz, M. (2005). Age of onset of generalized anxiety disorder in older adults. Am J Geriatr Psychiatry, 13, 23-30. Wetherell, J. L., & Gatz, M. (2005). The Beck Anxiety Inventory in older adults with generalized anxiety disorder. J Psychopathology Behav Assess, 27, 17-24. Wetherell, J. L., Hopko, D. R., Diefenbach, G. J., Averill, P. M., Beck, J. G., Craske, M. G., Gatz, M., Novy, D. M., & Stanley, M. A. (2005). Cognitive-behavioral therapy for late-life generalized anxiety disorder: Who gets better? Behav Ther, 36, 147-156. PHS 398/2590 (Rev. 09/04) Page _______ Biographical Sketch Format Page Principal Investigator (last, first, middle): McHugo, G.J., Kammerer, N., Jackson, E.W., Markoff, L.S., Gatz, M., Larson, M.J., Mazelis, R., & Hennigan K. (2005). Women, Co-Occurring Disorders, and Violence Study: Evaluation design and study population. J Subst Abuse Treat, 28, 91-107. Morrissey, J.P., Ellis, A.R., Gatz, M., Amaro, H., Reed, B.G., Savage, A., Finkelstein, N., Mazelis, R., Brown, V., Jackson, E.W., & Banks, S. (2005). Outcomes for women with co-occurring disorders and trauma: program and person-level effects. J Subst Abuse Treat. 28, 121-133. Gatz, M., Russell, L.A., Grady, J., Kram-Fernandez, D. Clark, C., & Marshall, B. (2005). Women’s recollections of victimization, psychological problems, and substance use. J Community Psychol, 33, 479-493. Becker, M. A., Noether, C. D., Larson, M. J., Gatz, M., Brown, V., Heckman, J. P., & Giard, J. (2005). Characteristics of women engaged in treatment for trauma and co-occurring disorders: Findings from a national multisite study. J Community Psychol, 33, 429-443. Jin, Y-P., Gatz, M., Johansson, B., & Pedersen, N.L. (2004). Sensitivity and specificity of dementia coding in two Swedish disease registries. Neurology, 63, 739-741. Katzov, H., Bennet, A., Kehoe, P., Wiman, B., Gatz, M., Blennow, K., Lenhard, B., Pedersen, N.L., deFaire, U., & Prince, J.A. (2004). A cladistic model of ACE sequence variation with implications for myocardial infarction, Alzheimer’s disease, and obesity. Hum Mol Genet,13, 2647-2657. Serrano J.P., Latorre, J.M., Gatz, M., & Montanes, J. (2004). Life review therapy using autobiographical retrieval practice for older adults with depressive symptomatology. Psychol Aging,19, 272-277. Kehoe, P.G., Katzov, H., Andreasen, N., Gatz, M., Wilcock, G.K., Cairns, N.J., Palmgren, J., De Faire, U., Brookes, A.J., Pedersen, N.L., Blennow, K., & Prince, J.A. (2004). Common variants of ACE contribute to variable age-at-onset of Alzheimer's disease. Hum Genet, 114, 478-483. Katzov, H., Chalmers, K., Palmgren, J., Andreasen, N., Johansson, B., Cairns, N.J., Gatz, M., Wilcock, G.K., Love, S., Pedersen, N.L., Brookes, A.J., Blennow, K., Kehoe, P.G., & Prince, J.A. (2004). Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism. Hum Mutat, 23, 358-367. Pedersen, N.L., Gatz, M., Berg, S., & Johnasson, B. (2004). How heritable is Alzheimer's disease late in life? Findings from Swedish Twins. Ann Neurol, 55, 180-185. Wirdefeldt, K., Gatz, M., Schalling, M., & Pedersen, N.L. (2004). No evidence for heritability of Parkinson’s Disease in Swedish twins. Neurology, 63, 305-311. Watari, K., & Gatz, M. (2004). Pathways to care for Alzheimer's disease among Korean Americans. Cultur Divers Ethnic Minor Psychol, 10, 23-38. Wetherell, J.L., Thorp, S.R., Patterson, T.L., Golshan, S., Jeste, D.V., & Gatz M. (2004). Quality of life in geriatric generalized anxiety disorder: a preliminary investigation. J Psychiatr Res, 38, 305-312. Jansson, M., Gatz, M., Berg, S., Johansson, B., Malmberg, B., McClearn, G.E., Schalling, M., & Pedersen, N.L. (2004). Gender differences in heritability of depressive symptoms in the elderly. Psychol Med, 34, 471-479. Suthers, K.M., Gatz, M., & Fiske, A. (2004). Screening for depression: A comparative analysis of the 11-item CES-D and the CIDI-SF. J Ment Health Aging, 10, 209-219. Wetherell, J. L., Le Roux, H., & Gatz, M. (2003). DSM-IV criteria for generalized anxiety disorder in older adults: Distinguishing the worried from the well. Psychol Aging, 18, 622-627. Reynolds, C.F., III, & Gatz, M. (2003). Research training in mental health and aging: The harvest is plentiful; the laborers, few. Am J Geriatr Psychiatry, 11, 267-270. Fiske, A., Gatz, M., & Pedersen, N. L. (2003). Depressive symptoms and aging: The effects of illness and nonhealth related events. J Gerontol B Psychol Sci Soc Sci, 58, P320-P328. Gatz, M., Fiske, A., Reynolds, C.A., Wetherell, J.L., Johansson, B., & Pedersen, N.L. (2003). Sex differences in genetic risk for dementia. Behav Genet, 33, 95-105. Finkel, D., Reynolds, C.A., McArdle, J.J., Gatz, M., & Pedersen, N.L. (2003). Latent growth curve analyses of accelerating decline in cognitive abilities in adulthood. Dev Psychol, 39, 535-550. Crowe, M., Andel, R., Pedersen, N.L., Johansson, B., & Gatz, M. (2003). Does participation in leisure activities lead to reduced risk of Alzheimer’s disease? A prospective study of Swedish twins. J Gerontol B Psychol Sci Soc Sci, 58, P249-P255. Gatz, M. & Fiske, A. (2003). Aging women and depression. Prof Psychol Res Practice, 34, 3-9. Ripatti, S., Gatz, M., Pedersen, N.L., & Palmgren, J. (2003). A three-state frailty model for age at onset of dementia and death in Swedish twins. Genet Epidemiol, 24, 139-149. Wetherell, J.L., Gatz, M., & Craske, M.G. (2003). Treatment of generalized anxiety disorder in older adults. J Consult Clin Psychol, 71, 31-40. PHS 398/2590 (Rev. 09/04) Page _______ Biographical Sketch Format Page Principal Investigator (last, first, middle): C. Research Support Ongoing Research Support R01 AG10175 (Pedersen, PI) 09/30/03 - 08/31/07 PHS (NIH) Genetic and Environmental Influences—Behavioral Aging The major goal of this project, known as the Swedish Adoption/Twin Study of Aging, is to examine the importance of genetic and environmental influences on individual differences in biobehavioral aging. Role: Co-Investigator R01 ES10758 (Pedersen, PI) 05/01/01 - 04/30/06 PHS (NIH) Environmental Factors for Parkinson’s in Swedish Twins The major goal of this project is to assess the importance of environmental factors for Parkinson’s disease in a population-based sample of Swedish twins. Role: Co-Principal Investigator P50 AG05142 (Chui, PI) 04/01/04 – 03/31/09 Alzheimer Disease Research Center The purpose of this project focuses reducing the cognitive and behavioral impact of AD and CVD among ethnically diverse populations, encompassing research from basic biological mechanisms of Alzheimer disease to health services research. Role: Director of Education, Information Transfer Core R03 CA119697 (Gatz, PI) 09/30/05 – 08/31/07 PHS (NIH) A Twin Study of Cognitive Outcomes in Older Adult Cancer Survivors This project addresses the long term cognitive impact of cancer and its treatment on older adults through secondary analysis using the population-based Swedish Twin Registry and the Study of Dementia in Swedish Twins. Role: Principal Investigator PHS 398/2590 (Rev. 09/04) Page _______ Biographical Sketch Format Page Principal Investigator (last, first, middle): PHS 398/2590 (Rev. 09/04) Page _______ Biographical Sketch Format Page