NIH Biosketch - University of Southern California

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Principal Investigator (last, first, middle):
BIOGRAPHICAL SKETCH
NAME
POSITION TITLE
Margaret Gatz
Professor
eRA COMMONS USER NAME
margat
INSTITUTION AND LOCATION
Rhodes College, Memphis, TN
Duke University, Durham, NC
Center for the Study of Aging and Human
Development, Duke University Medical Center
DEGREE
YEAR(s)
B.A.
Ph.D.
Postdoctoral
Research Fellow
1966
1972
1972-1973
FIELD OF STUDY
Psychology
Clinical Psychology
Gerontology
A. Positions and Honors.
1973-78
University of Maryland: Assistant Professor (1973-78), Associate Professor (1978)
1979-University of Southern California: Associate Professor (1979-85), Full Professor (1985--)
1997
Distinguished Mentorship Award, Behavioral & Social Sci., Gerontological Society of America
1999
Master Mentor Award, Div. 20, Am. Psychological Assoc., Retirement Research Foundation
2000-Foreign Adjunct Professor, The Karolinska Institute, Department of Medical Epidemiology
2003-2004
Zenith Award, Alzheimer’s Association
2005
APA Committee on Aging, Award for the Advancement of Psychology and Aging
2005
Distinguished Research Achievement Award, Division 20, American Psychological Assoc.
B. Selected peer-reviewed publications (last three years).
Andel, R., Crowe, M., Pedersen, N.L., Mortimer, J., Crimmins, E., Johansson, B., & Gatz, M. (2005).
Complexity of work and risk of Alzheimer’s disease: A population-based study of Swedish twins. J Gerontol
B Psychol Sci Soc Sci, 60, 251-258
Fiske, A., Gatz, M., Aadnøy, B., & Pedersen, N.L. (2005). Assessing age of dementia onset: Validity of
informant reports. Alzheimer Dis Assoc Disord, 19, 128-134.
Gatz, M., Fratiglioni, L., Johansson, B., Berg, S., Mortimer, J.A., Reynolds, C.A., Fiske, A., & Pedersen,
N.L.. (2005). Complete ascertainment of dementia in the Swedish Twin Registry: the HARMONY study.
Neurobiol Aging, 26, 439-447.
Heflin, L. H., Meyerowitz, B. E., Hall, P., Lichtenstein, P., Johansson, B., Pedersen, N. L., & Gatz, M. (2005).
Cancer as a risk factor for long-term cognitive deficits and dementia. J Natl Cancer Inst, 9, 854–856.
Reynolds, C. A., Turner, A., Gatz, M., & Pedersen, N. L. (2005). Comparative Rating Measures of Health and
Environmental Exposures: How Well Do Twins Agree? Twin Res, 8, 113-119.
Gatz, M. (2005). Educating the brain to avoid dementia: Can mental exercise prevent Alzheimer disease?
PLoS Med, 2, 38-40.
Rasgon, N.L., Magnusson, C., Johansson, A.L.V., Pedersen, N.L., Elman, S, & Gatz, M. (2005). Endogenous
and exogenous hormone exposure and risk of cognitive impairment in Swedish twins: A preliminary study.
Psychoneuroendocrinology, 30, 558-567.
Fiske, A., Gatz, M., & Hannell, E. (2005). Rural suicide rates and availability of health care providers. J
Community Psychol, 33, 537-543.
Wirdefeldt, K., Gatz, M., Pawitan, Y., & Pedersen, N.L. (2005). Risk and protective factors for Parkinson's
disease: A study in Swedish twins. Ann Neurol, 57, 27-33.
Reynolds, C.A., Finkel, D., McArdle, J.J, Gatz, M., Berg, S. & Pedersen, N.L. (2005). Quantitative genetic
analysis of latent growth curve models of cognitive abilities in adulthood. Dev Psychol, 41, 3-16.
Heller, K., Alexander, D.B., Gatz, M., Knight, B.G., & Rose, T. (2005). Social and personal factors as predictors
of earthquake preparation: The role of support provision, network discussion, negative affect, age, and
education. J Appl Soc Psyc, 35, 399-422.
Le Roux, H., Wetherell, J.L., & Gatz, M. (2005). Age of onset of generalized anxiety disorder in older adults.
Am J Geriatr Psychiatry, 13, 23-30.
Wetherell, J. L., & Gatz, M. (2005). The Beck Anxiety Inventory in older adults with generalized anxiety
disorder. J Psychopathology Behav Assess, 27, 17-24.
Wetherell, J. L., Hopko, D. R., Diefenbach, G. J., Averill, P. M., Beck, J. G., Craske, M. G., Gatz, M., Novy, D.
M., & Stanley, M. A. (2005). Cognitive-behavioral therapy for late-life generalized anxiety disorder: Who
gets better? Behav Ther, 36, 147-156.
 PHS 398/2590 (Rev. 09/04)
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Principal Investigator (last, first, middle):
McHugo, G.J., Kammerer, N., Jackson, E.W., Markoff, L.S., Gatz, M., Larson, M.J., Mazelis, R., & Hennigan K.
(2005). Women, Co-Occurring Disorders, and Violence Study: Evaluation design and study population. J
Subst Abuse Treat, 28, 91-107.
Morrissey, J.P., Ellis, A.R., Gatz, M., Amaro, H., Reed, B.G., Savage, A., Finkelstein, N., Mazelis, R., Brown,
V., Jackson, E.W., & Banks, S. (2005). Outcomes for women with co-occurring disorders and trauma:
program and person-level effects. J Subst Abuse Treat. 28, 121-133.
Gatz, M., Russell, L.A., Grady, J., Kram-Fernandez, D. Clark, C., & Marshall, B. (2005). Women’s recollections
of victimization, psychological problems, and substance use. J Community Psychol, 33, 479-493.
Becker, M. A., Noether, C. D., Larson, M. J., Gatz, M., Brown, V., Heckman, J. P., & Giard, J. (2005).
Characteristics of women engaged in treatment for trauma and co-occurring disorders: Findings from a
national multisite study. J Community Psychol, 33, 429-443.
Jin, Y-P., Gatz, M., Johansson, B., & Pedersen, N.L. (2004). Sensitivity and specificity of dementia coding in
two Swedish disease registries. Neurology, 63, 739-741.
Katzov, H., Bennet, A., Kehoe, P., Wiman, B., Gatz, M., Blennow, K., Lenhard, B., Pedersen, N.L., deFaire, U.,
& Prince, J.A. (2004). A cladistic model of ACE sequence variation with implications for myocardial
infarction, Alzheimer’s disease, and obesity. Hum Mol Genet,13, 2647-2657.
Serrano J.P., Latorre, J.M., Gatz, M., & Montanes, J. (2004). Life review therapy using autobiographical
retrieval practice for older adults with depressive symptomatology. Psychol Aging,19, 272-277.
Kehoe, P.G., Katzov, H., Andreasen, N., Gatz, M., Wilcock, G.K., Cairns, N.J., Palmgren, J., De Faire, U.,
Brookes, A.J., Pedersen, N.L., Blennow, K., & Prince, J.A. (2004). Common variants of ACE contribute to
variable age-at-onset of Alzheimer's disease. Hum Genet, 114, 478-483.
Katzov, H., Chalmers, K., Palmgren, J., Andreasen, N., Johansson, B., Cairns, N.J., Gatz, M., Wilcock, G.K.,
Love, S., Pedersen, N.L., Brookes, A.J., Blennow, K., Kehoe, P.G., & Prince, J.A. (2004). Genetic variants
of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism. Hum
Mutat, 23, 358-367.
Pedersen, N.L., Gatz, M., Berg, S., & Johnasson, B. (2004). How heritable is Alzheimer's disease late in
life? Findings from Swedish Twins. Ann Neurol, 55, 180-185.
Wirdefeldt, K., Gatz, M., Schalling, M., & Pedersen, N.L. (2004). No evidence for heritability of Parkinson’s
Disease in Swedish twins. Neurology, 63, 305-311.
Watari, K., & Gatz, M. (2004). Pathways to care for Alzheimer's disease among Korean Americans. Cultur
Divers Ethnic Minor Psychol, 10, 23-38.
Wetherell, J.L., Thorp, S.R., Patterson, T.L., Golshan, S., Jeste, D.V., & Gatz M. (2004). Quality of life in
geriatric generalized anxiety disorder: a preliminary investigation. J Psychiatr Res, 38, 305-312.
Jansson, M., Gatz, M., Berg, S., Johansson, B., Malmberg, B., McClearn, G.E., Schalling, M., & Pedersen,
N.L. (2004). Gender differences in heritability of depressive symptoms in the elderly. Psychol Med, 34,
471-479.
Suthers, K.M., Gatz, M., & Fiske, A. (2004). Screening for depression: A comparative analysis of the 11-item
CES-D and the CIDI-SF. J Ment Health Aging, 10, 209-219.
Wetherell, J. L., Le Roux, H., & Gatz, M. (2003). DSM-IV criteria for generalized anxiety disorder in older
adults: Distinguishing the worried from the well. Psychol Aging, 18, 622-627.
Reynolds, C.F., III, & Gatz, M. (2003). Research training in mental health and aging: The harvest is plentiful;
the laborers, few. Am J Geriatr Psychiatry, 11, 267-270.
Fiske, A., Gatz, M., & Pedersen, N. L. (2003). Depressive symptoms and aging: The effects of illness and nonhealth related events. J Gerontol B Psychol Sci Soc Sci, 58, P320-P328.
Gatz, M., Fiske, A., Reynolds, C.A., Wetherell, J.L., Johansson, B., & Pedersen, N.L. (2003). Sex differences
in genetic risk for dementia. Behav Genet, 33, 95-105.
Finkel, D., Reynolds, C.A., McArdle, J.J., Gatz, M., & Pedersen, N.L. (2003). Latent growth curve analyses of
accelerating decline in cognitive abilities in adulthood. Dev Psychol, 39, 535-550.
Crowe, M., Andel, R., Pedersen, N.L., Johansson, B., & Gatz, M. (2003). Does participation in leisure activities
lead to reduced risk of Alzheimer’s disease? A prospective study of Swedish twins. J Gerontol B Psychol
Sci Soc Sci, 58, P249-P255.
Gatz, M. & Fiske, A. (2003). Aging women and depression. Prof Psychol Res Practice, 34, 3-9.
Ripatti, S., Gatz, M., Pedersen, N.L., & Palmgren, J. (2003). A three-state frailty model for age at onset of
dementia and death in Swedish twins. Genet Epidemiol, 24, 139-149.
Wetherell, J.L., Gatz, M., & Craske, M.G. (2003). Treatment of generalized anxiety disorder in older adults. J
Consult Clin Psychol, 71, 31-40.
 PHS 398/2590 (Rev. 09/04)
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Principal Investigator (last, first, middle):
C. Research Support
Ongoing Research Support
R01 AG10175
(Pedersen, PI)
09/30/03 - 08/31/07
PHS (NIH)
Genetic and Environmental Influences—Behavioral Aging
The major goal of this project, known as the Swedish Adoption/Twin Study of Aging, is to examine the
importance of genetic and environmental influences on individual differences in biobehavioral aging.
Role: Co-Investigator
R01 ES10758
(Pedersen, PI)
05/01/01 - 04/30/06
PHS (NIH)
Environmental Factors for Parkinson’s in Swedish Twins
The major goal of this project is to assess the importance of environmental factors for Parkinson’s disease in a
population-based sample of Swedish twins.
Role: Co-Principal Investigator
P50 AG05142
(Chui, PI)
04/01/04 – 03/31/09
Alzheimer Disease Research Center
The purpose of this project focuses reducing the cognitive and behavioral impact of AD and CVD among
ethnically diverse populations, encompassing research from basic biological mechanisms of Alzheimer disease
to health services research.
Role: Director of Education, Information Transfer Core
R03 CA119697
(Gatz, PI)
09/30/05 – 08/31/07
PHS (NIH)
A Twin Study of Cognitive Outcomes in Older Adult Cancer Survivors
This project addresses the long term cognitive impact of cancer and its treatment on older adults through
secondary analysis using the population-based Swedish Twin Registry and the Study of Dementia in Swedish
Twins.
Role: Principal Investigator
 PHS 398/2590 (Rev. 09/04)
Page _______
Biographical Sketch Format Page 
Principal Investigator (last, first, middle):
 PHS 398/2590 (Rev. 09/04)
Page _______
Biographical Sketch Format Page 
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