4-5 B2

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Dr. Hui-Chun Huang
Contact Information
Phone
Email
+886-2-27812121 Ext. 3353
[email protected]
Personal photo
Educations
M.D. National Yang-Ming University School of Medicine, Taiwan
Experiences
Assistant Professor in Medicine, National Yang-Ming University School of
Medicine, Taiwan
Resident in Medicine, Taipei Veterans General Hospital, Taiwan
Chief Resident in Gastroenterology, Taipei Veterans General Hospital, Taiwan
Attending physician in Gastroenterology, Taipei Veterans General Hospital,
Taiwan
Research Interests
1. The pharmacological study on portal-systemic collateral vascular system in
portal hypertension and liver cirrhosis
2. The mechanism of the development and control of hemorrhage of
portal-systemic collateral vascular system in portal hypertension and liver
cirrhosis
3. Hepatic encephalopathy
4. Hepatopulmonary syndrome
Honors and Awards
2008
The best teacher selected by students in National Yang-Ming
University School of Meidicine
2006
2006
2003
The best teacher selected by students in National Yang-Ming
University School of Meidicine
The annual best teacher in Taipei Veterans General Hospital
The best teacher selected by students in National Yang-Ming
University School of Meidicine
Selected publications
1. Chang CC, Lee WS, Huang HC, Lee FY, Wang SS, Lin HC, Nong JY, Lee SD. Aliskiren
reduces portal pressure in portal hypertensive rats. Eur J Clin Invest 2011
(accepted).
2. Chang CC, Wang SS, Huang HC, Chan CY, Lee FY, Lin HC, Nong JY, Chuang CL, Lee SD.
Selective cyclooxygenase inhibition improves hepatic encephalopathy in fulminant
hepatic failure of rat. Eur J Pharmacol 2011;666:226-32.
3. Huang HC, Haq O, Utsumi T, Sethasine S, Abraldes JG, Groszmann RJ, Iwakiri Y.
Intestinal and plasma VEGF levels in cirrhosis: The role of portal pressure. J Cell Mol
Med 2011 Jul 31. doi: 10.1111/j.1582-4934.2011.01399.x. [Epub ahead of print]
4. Lee JY, Huo TI, Huang H*, Lee FY, Lin HC, Chuang CL, Chang CC, Wang SS, Lee SD.
Propranolol modulates the collateral vascular responsiveness to vasopressin via
Gα-mediated pathway in portal hypertensive rats. Clin Sci (Lond) 2011 Jul 8. [Epub
ahead of print](corresponding author)
5. Huang HC, Chang CC, Wang SS, Chan CY, Lee FY, Chuang CL, Hsin IF, Teng TH, Lin
HC, Lee SD. Pravastatin for thioacetamide-induced hepatic failure and
encephalopathy. Eur J Clin Invest 2011 Jun 7. doi: 10.1111/j.1365-2362.2011.
02566.x. [Epub ahead of print]
6. Hsin IF, Hsu CY, Huang HC, Huang YH, Lin HC, Lee RC, Chiang JH, Lee FY, Huo TI, Lee
SD. Liver failure after transarterial chemoembolization for patients with
hepatocellular carcinoma and ascites: incidence, risk factors, and prognostic
prediction. J Clin Gastroenterol 2011;45:556-62.
7. Zhang D, Utsumi T, Huang HC, Gao L, Sangwung P, Chung C, Shibao K, Okamoto K,
Yamaguchi K, Groszmann RJ, Jozsef L, Hao A, Sessa WC, Iwakiri Y. Reticulon 4B
(Nogo-B) is a novel regulator of hepatic fibrosis. Hepatology Accepted manuscript
online: 2011 JAN 19.
8.Huang HC, Wang SS, Lee JY, Chen YC, Lee FY, Lin HC, Chang CC, Lee SD. Simvastatin
effects on portal-systemic collaterals of portal hypertensive rats. J Gastroenterol
Hepatol 2010;25:1401-9.
9.Chang CC, Wang SS, Huang HC, Lee JY, Lee FY, Lin HC, Lee SD. Pravastatin
administration does not induce detrimental effects on hemodynamics and
collaterals of portal hypertensive rats. J Gastroenterol Hepatol 2010;25:1394-400.
10.Hsu CY, Lee FY, Huo TI, Chan CY, Huang HC (corresponding author), Lin HC, Chang
CC, Teng TH, Wang SS, Lee SD. Lack of therapeutic effects of gabexate mesilate on
the hepatic encephalopathy in rats with acute and chronic hepatic failure. J
Gastroenterol Hepatol 2010;25:1321-8.
11.Huang HC, Lee FY, Huo TI. Major adverse events, pretransplant assessment and
outcome prediction. J Gastroenterol Hepatol 2009;24:1716-24.
12.Huang YH, Hung HH, Chan CC, Lai CR, Chu CJ, Huo TI, Lee PC, Su CW, Lan KH, Huang
HC, Lee IC, Lin HC, Lee SD. Core antigen expression is associated with hepatic
necroinflammation in e antigen-negative chronic hepatitis B patients with low DNA
loads. Clin Vaccine Immunol 2010;17:1048-53.
13.Huang HC, Wang SS, Chang CC, Lee FY, Lin HC, Hou MC, Teng TH, Chen YC, Lee SD.
Evolution of portal-systemic collateral vasopressin response in endotoxemic portal
hypertensive rats. Shock 2009;32:503-8.
14.Huang HC, Wang SS, Lee FY, Chang CC, Chang FY, Lin HC, Hou MC, Lee SD.
Vasopressin response and shunting modulation in cirrhotic rats by chronic nitric
oxide inhibition. J Gastroenterol Hepatol 2008;23:e265-9.
15.Huang HC, Wang SS, Lee FY, Chan CY, Chang FY, Lin HC, Chu CJ, Chen YC, Lee SD.
Simvastatin for rats with thioacetamide-induced liver failure and encephalopathy. J
Gastroenterol Hepatol 2008;23:e236-42.
16.Huang HC, Wang SS, Chen YC, Lee FY, Chang FY, Lin HC, Hou MC, Chang CC, Lee SD.
Chronic cyclooxygenase blockade enhances the vasopressin responsiveness in
collaterals of portal hypertensive rats. Scand J Gastroenterol 2006;41:1440-5.
17.Huo TI, Huang YH, Huang HC, Wu JC, Lee PC, Chang FY, Lee SD. Fever and infectious
complications after percutaneous acetic acid injection therapy for hepatocellular
carcinoma: incidence and risk factor analysis. J Clin Gastroenterol 2006;40:639-42.
18.Chan CY, Lee FY, Wang TF, Huang SW, Chang FY, Lu RH, Chen YC, Wang SS, Huang
HC, Lee SD. Lack of detrimental or therapeutic effects of cyclooxygenase inhibition
in bile duct-ligated rats with hepatic encephalopathy. J Gastroenterol Hepatol
2006;21:1483-7.
19.Chu CJ, Chang CC, Wang TF, Lee FY, Chang FY, Chen YC, Chan CC, Huang HC, Wang
SS, Lee SD. Detrimental effects of nitric oxide inhibition on hepatic encephalopathy
in rats with thioacetamide-induced fulminant hepatic failure: role of nitric oxide
synthase isoforms. J Gastroenterol Hepatol 2006;21:1194-9.
20.Chan CC, Chang CC, Huang HC, Wang SS, Lee FY, Chang FY, Lin HC, Tai CC, Lee SD.
Effects of norepinephrine and acetylcholine on portal-systemic collaterals of
common bile duct-ligated cirrhotic rat. J Gastroenterol Hepatol 2005;20:1867-72.
21.Chan CC, Wang SS, Lee FY, Chang FY, Lin HC, Hou MC, Huang HC, Lee SD. Effects of
vasopressin on portal-systemic collaterals of cirrhotic rats. Scand J Gastroenterol
2005;40:83-9.
22.Chen CT, Chu CJ, Wang TF, Lu RH, Lee FY, Chang FY, Lin HC, Chan CC, Wang SS,
Huang HC, Lee SD. Evidence against a role for endotoxin in the hepatic
encephalopathy of rats with thioacetamide-induced fulminant hepatic failure. J
Gastroenterol Hepatol 2005;20:450-5.
23.Chu CJ, Hsiao CC, Wang TF, Chan CY, Lee FY, Chang FY, Chen YC, Huang HC, Wang SS,
Lee SD. Prostacyclin inhibition by indomethacin aggravates hepatic damage and
encephalopathy in rats with thioacetamide-induced fulminant hepatic failure.
World J Gastroenterol 2005;11:232-6.
24.Chan CC, Wang SS, Lee FY, Chang FY, Lin HC, Hou MC, Huang HC, Lee SD. Effects of
endothelin-1 on portal-systemic collaterals of common bile duct-ligated cirrhotic
rats. Eur J Clin Invest 2004;34:290-6.
25.Chan CY, Huang SW, Wang TF, Lu RH, Lee FY, Chang FY, Chu CJ, Chen YC, Chan CC,
Huang HC, Lee SD. Lack of detrimental effects of nitric oxide inhibition in bile
duct-ligated rats with hepatic encephalopathy. Eur J Clin Invest 2004;34:122-8.
26.Huang HC, Wang SS, Chan CC, Lee FY, Chang FY, Lin HC, Hou MC, Tai CC, Lai IN, Lee
SD. Chronic inhibition of nitric oxide increases the collateral vascular responsiveness
to vasopressin in portal hypertensive rats. J Hepatol 2004;40:234-8.
27. Huang HC, Wang SS, Chen YC, Lee FY, Chang FY, Lin HC, Hou MC, Chan CC, Chen CT,
Wu SL, Lee SD. Cyclooxygenase expression in splanchnic hyposensitivity to
glypressin of bleeding portal hypertensive rats. Eur J Clin Invest 2003;33:505-12.
28.Wang SS, Chan CC, Lee FY, Chang FY, Lin HC, Chen CT, Huang HC, Tai CC, Lai IN, Lee
SD. Effects of long-term octreotide treatment on the response of portal-systemic
collaterals to vasopressin in portal hypertensive rats. Eur J Clin Invest
2002;32:316-21.
29.Huang HC, Lee FY, Chan CC, Chang FY, Wang SS, Lin HC, Hou MC, Chen CT, Tai CC,
Lai IN, Lee SD. Effects of somatostatin and octreotide on portal-systemic collaterals
in portal hypertensive rats. J Hepatol 2002;36:163-8.
30.Chan CC, Wang SS, Lee FY, Chang FY, Lin HC, Chu CJ, Chen CT, Huang HC, Lee SD.
Endothelin-1 induces vasoconstriction on portal-systemic collaterals of portal
hypertensive rats. Hepatology 2001;33:816-20.
31.Huang HC, Chu CJ, Lee FY, Chang FY, Wang SS, Lin HC, Hou MC, Chan CC, Wu SL,
Chen CT, Lee SD. Chronic inhibition of nitric oxide ameliorates splanchnic
hyposensitivity to glypressin in a hemorrhage- transfused rat model of portal
hypertension. Scand J Gastroenterol 2000;35:1308-13.
32.Chu CJ, Wang SS, Lee FY, Chang FY, Lin HC, Hou MC, Chan CC, Wu SL, Chen CT,
Huang HC, Lee SD. Detrimental effects of nitric oxide inhibition on hepatic
encephalopathy in rats with thioacetamide-induced fulminant hepatic failure. Eur J
Clin Invest 2001;31:156-63.
33.Lee FY, Chu CJ, Wang SS, Chang FY, Lin HC, Hou MC, Chan CC, Wu SL, Chen CT,
Huang HC, Lee SD. Inhibition of prostacyclin by indomethacin ameliorates the
splanchnic hyposensitivity to glypressin in haemorrhage-transfused common bile
duct-ligated rats. Eur J Clin Invest 2001;31:145-53.
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