Pubblicazioni
1. Bellia, F., Vecchio, G., Rizzarelli, E. Carnosine derivatives: New multifunctional drug-like
molecules. Amino Acids, (2012), 153-163.
2. V Oliveri, ML Giuffrida, G Vecchio, C Aiello, M. Viale Gluconjugates of 8-hydroxyquinolines
as potential anti-cancer prodrugs Dalton Trans 2012, 41, 4530-4535.
3. Puglisi A., Spencer J., Oliveri V., Vecchio G., Kong X., Clarke J., Milton J., Synthesis,
Physicochemical Properties and Antioxidant Activity of Deferiprone-Cyclodextrin Conjugates
and their Iron(III) Complexes Dalton Trans., 2012, 41 (10), 2877 - 2883
4. V., Bellia, F., Vecchio, G., Rizzarelli, E., Cuzzocrea S, Calabrese V., Neuroprotective features
of carnosine in oxidative driven diseases, Mol Aspects Med. 2011, 32.258-66.
5. Di Paola R, Impellizzeri D, Salinaro A T, Mazzon E, Bellia Francesco, Cavallaro M, Cornelius
C, Vecchio G, Calabrese V, Rizzarelli E, Cuzzocrea S. Administration of carnosine in the
treatment of acute spinal cord injury. Biochem. Pharmacol., 2011, vol. 82, p. 1478-1489.
6. G. I. Grasso, G. Arena F. Bellia, G. Maccarrone, M. Parrinello, A. Pietropaolo, E. Rizzarelli
'Intramolecular Weak Interactions in the Thermodynamic Stereoselectivity of Copper(II)
Complexes with Carnosine-trehalose Conjugates Chem. Eur. J. 2011, 17, 9448-9455
7. Grasso, G.I., Bellia, F., Arena, G., Vecchio, G., Rizzarelli, E. Inorg Chem. 50, 4917-4924.
8. V.Lanza, F.Bellia, R.D’Agata, G. Grasso, E.Rizzarelli, G. Vecchio New glycoside derivatives
of carnosine and analogs resistent to carnosinase hydrolysis: Synthesis and characterization of
their copper(II) complexes J. Inorg.Biochem., 105 (2011) 181-188.
9. V. Oliveri, A. Puglisi, G. Vecchio New conjugates of β-cyclodextrin with manganese(III)
salophen and porphyrin complexes as antioxidant systems Dalton Trans., 40 (2011) 2913-2919.
10.V.Oliveri, G.Vecchio A novel artificial superoxide dismutase: non-covalent conjugation of
albumin with a MnIII salophen-type complex Eur. J. Med.Chem. 46, 961 (2011).
11.V. Cucinotta, A. Giuffrida, G. Grasso, G. Maccarrone, A. Mazzaglia, M. Messina, G. Vecchio
Diaminotrehalose-capped b-cyclodextrin, a new member of hemispherodextrins: Synthesis,
thermodynamic and spectroscopic characterization and its exploitation in chiral electrokinetic
chromatography J. Sep. Sci. 34 70, (2011).
12.V. Lanza, F. Bellia, R. D'Agata, G. Grasso, E. Rizzarelli, G. Vecchio New glycoside
derivatives of carnosine and analogs resistant to carnosinase J.Inorg.Biochem 105,
(2011).
181
13.V. Lanza, G. Vecchio : Synthesis of Superoxide Dismutase (SOD) mimetics A bioinorganic
laboratory experiment. J.Chem.Ed., 86, 1419 (2009).
14. E. Benedetti, R. Iacovino, C. Pedone, A. Puglisi, E. Rizzarelli, M. Saviano, G. Vecchio
Crystal and molecular structure of β-cyclodextrins functionalized with the anti-inflammatory
drug Etodolac Biopolymers, 91, 1227 (2009).
15. V. Lanza, G. Vecchio New conjugates of superoxide dismutase/catalase mimetics with
cyclodextrins J.Inorg.Biochem., 103, 381(2009).
16. F.Bellia, D. La Mendola, C.Pedone, E.Rizzarelli, M.Saviano, G.Vecchio Selectively
functionalized cyclodextrins and their metal complexes, Chem. Soc. Rev. 38, 2756 (2009).
17. A.Contino V.Cucinotta, A.Giuffrida, G.Maccarrone, M.Messina, A.Puglisi, G.Vecchio
Synthesis and characterisation of the 3-amino-derivative of γ-cyclodextrin, showing receptor
ability and metal ion coordination properties Tetrahedron Lett., 49 4765 (2008).
18. F. Bellia, A.M.Amorini, D. La Mendola, G. Vecchio, B. Tavazzi, B. Giardina, V. Di Pietro,
G. Lazzarino, E. Rizzarelli, New glycosidic derivatives of histidine-containing dipeptides with
antioxidant properties and resistano to carnosinase activity. Eur. J. Med. Chem., 43, 373
(2008).
19. R. D’Agata, G. Iacono, V. Lanza, G. Spoto, G. Vecchio Lectin Recognition of 1,4,8,11tetraazacyclotetradecane glycoconjugates and their copper(II) complexes J Inorg. Biochem.,
12 (supl 1), S49 (2007).
20. F.Bellia, D.La Mendola, G.Maccarrone, P.Mineo, D.Vitalini, E.Scamporrino, S.Sortino,
G.Vecchio, E.Rizzarelli Copper(II) complexes with the -cyclodextrin homocarnosine
conjugates and their antioxidant activity Inorg, Chim. Acta 360 (2007) 945.
21. S. Cuzzocrea, T. Genovese, M. Failla, G. Vecchio, M. Fruciano, E. Mazzon, R. Di Paola, C.
Muia, C. La Rosa, N. Crimi, E. Rizzarelli, C. Vancheri,
Protective effect of orally
administered carnosine on bleomycin-induced lung injury. Am. J. Physiol. Lung Cell Mol
Physiol 292, L1095 (2007).
22. V. Cucinotta, A. Giuffrida, G.Grasso, G. Maccarrone, M. Messina, G. Vecchio High
selectivity in new chiral separations of dansyl -amino acida by cyclodextrin derivatives in
CD – EKC J.Cromatogr. A, 1155, 172-179 (2007).
23. V.Cucinotta, A.Giuffrida, G.Maccarrone, M.Messina, A.Puglisi, G.Vecchio Synthesis and
NMR characterization of β-alanine-bridged hemispherodextrin: a very efficient chiral selector
in EKC Electrophoresis, 28, 2580 (2007).
24. A.Puglisi, R.Purrello, E.Rizzarelli, S.Sortino, G.Vecchio - Spectroscopic and self-association
behavior of a porphyrin--cyclodextrin conjugate - New J. Chem., 31, 1499 (2007).
25. A.M.Amorini, F. Bellia, V. Di Pietro, B. Giardina, D. La Mendola, G. Lazzarino, S. Sortino,
B. Tavazzi; E. Rizzarelli, G. Vecchio, Synthesis and antioxidant activity of new
homocarnosine β-cyclodextrin conjugates. Eur. J. Med. Chem. 42, 910 (2007).
26. R. D’Agata, G.Grasso, G. Iacono, G. Spoto, G. Vecchio Lectin Recognition of a New SOD
Mimic Bioconjugate Studied with Surface Plasmon Resonance Imaging, Org. Biomol. Chem.,
2006, 610-612 (selected for publication on Chem. Biol.Virtual J. issue 4 (2006).
27. V.Cucinotta, A.Giuffrida, G.Maccarrone, M.Messina, G.Vecchio Ligand exchange capillary
electrophoresis by cyclodextrin derivatives, a powerful tool for enantiomeric separations
Electrophoresis 27, 1471 (2006).
28. V.Cucinotta, A.Giuffrida, G.Maccarrone, M.Messina, A.Puglisi, A.Torrisi, G.Vecchio The 6derivative of -cyclodextrin with succinic acid: a new chiral selector for CD-EKC J.
Pharm.Biomed. Anal. 39, 1009 (2005).
29. V.Cucinotta, A. Giuffrida, G. Maccarrone, M. Messina, A. Puglisi, E. Rizzarelli, G.Vecchio
Coordination Properties of 3-functionalized -cyclodextrins. Thermodynamic stereoselectivity
of copper(II) complexes of the A,B-diamino derivative and its exploitation in LECE, Dalton
Trans, 2005, 2731.
30. V.Cucinotta, A. Giuffrida, D. La Mendola, G.Maccarrone, A. Puglisi, E.Rizzarelli, G.
Vecchio 3-Amino derivative of -cyclodextrin: thermodynamics of copper(II) complexes and
exploitation of its enantioselectivity in the separation of amino acid racemates by ligand
exchange capillary electrophoresis J Chromatogr.B 800, 127 (2004).
31. P.Mineo, D. Vitalini, D. La Mendola, E. Rizzarelli, E. Scamporrino, G.Vecchio Coordination
features of difunctionalized -cyclodextrins with carnosine. ESI-MS and spectroscopic
investigations on 6A,6D-di-(-alanyl-L-histidine)-6A,6D-dideoxy--cyclodextrin and 6A,6Cdi-(-alanyl-L-histidine)-6A,6C-dideoxy--cyclodextrin and their copper(II) complexes – J.
Inorg. Biochem. 98, 254 (2004).
32. A.Puglisi, G.Tabbì, G.Vecchio Bioconjugates of cyclodextrins of manganese salen-type
ligand with superoxide dismutase activity J.Inorg.Biochem. 98, 969-976 (2004).
33. S.Giuffrida, G.G.Condorelli, L.L.Costanzo, I. L.Fragala, G. Ventimiglia, G.Vecchio,
Photochemical Mechanism of the Formation of Nanometer-Sized Copper by UV Irradiation of
Ethanol Bis(2,4-pentanedionato)copper(II) Solutions. Chem.Mat. 16, 1260 (2004).
34. R. P. Bonomo, V.Bruno, E.Conte, G.De Guidi, D. La Mendola, G. Maccarrone, F. Nicoletti,
E. Rizzarelli, S. Sortino, G. Vecchio Potentiometric, spectroscopic and antioxidant activity of
SOD mimics containing carnosine J.Chem.Soc.Dalton Trans 4406-4415 (2003).
35. V.Cucinotta, A. Giuffrida, G. Grasso, G. Maccarrone, G. Vecchio, Ligand exchange chiral
separations by cyclodextrin derivatives in capillary electrophoresis. Analyst 128, 134 (2003).
36. G.Maccarrone, E. Rizzarelli, G. Vecchio Synthesis and Coordination Properties of
Functionalized -Cyclodextrins. Thermodynamic of Proton and Copper(II) Complexes of 3Adeoxy-3A-(2-methylaminopyridine)-
2A(S),3A(R)--cyclodextrin
in
aqueous
solution.
Polyhedron 21, 1531 (2002) (invited paper).
37. P. Mineo, D.Vitalini; D La Mendola, E. Rizzarelli; E. Scamporrino; G. Vecchio, Electrospray
mass spectrometric studies of L-carnosine (-alanyl-L-histidine) complexes with copper(II) or
zinc ions in aqueous solution. Rapid Commun. Mass Sp. 16, 722 (2002).
38. R.P.Bonomo, G.Maccarrone, E.Rizzarelli, G.Vecchio Conformational Features and
Coordination Properties of Functionalized -Cyclodextrins. Formation, Stability and
Structure of Proton and Copper(II) Complexes of 3A-[1-(2-amino)ethylamino]-3A-deoxy2A(S),3A(R)--cyclodextrin Inorg.Chim.Acta 339 455 (2002). (Invited paper).
39. D. La Mendola, S.Sortino, G. Vecchio, E. Rizzarelli Synthesis of new carnosine derivatives of
-cyclodextrin and their .OH scavenger ability, Helv. Chim. Acta 85, 1633 (2002).
40. T.Campagna, R.Marchelli, E.Rizzarelli, G. Vecchio Synthesis and conformation of cyclodextrin functionalized with a phenylalanine derivative. Conformational changes induced
by metal ions. J.Supramol.Chem 1, 117 (2001).
41. V.Cucinotta, A.Giuffrida, G.Grasso, G.Maccarrone, G.Vecchio Hemispherecyclodextrins: a
new class of cyclodextrin derivatives, in capillary electrophoresys J. Chromatogr.A 916, 61
(2001).
42. M. Saviano, E. Benedetti, B. di Blasio, E. Gavuzzo, C. Pedone, E. Rizzarelli, G. Vecchio.
Branched -Cyclodextrins: Synthesis and X-Ray Diffraction Structure of 6I,6II-di[2-(2aminoethyl)pyridine]-6I,6II-dideoxy--cyclomalto heptaose, Perkin Trans 2, 946 (2001).
43. R.P. Bonomo, V.Cucinotta, G.Maccarrone, E.Rizzarelli, G.Vecchio Thermodynamic
Stereoselectivity Assisted by Weak Interactions in Metal Complexes. Chiral Recognition of
L/D-Amino
Acids
by
the
Copper(II)
Complex
of
6-Deoxy-6-[4-(2-
aminoethyl)imidazolyl]cyclomaltoheptaose J.Chem.Soc., Dalton Trans. 1366 (2001).
44. V.Cucinotta, A.Giuffrida, G.Grasso, G.Maccarrone, G.Vecchio New cyclodextrin derivative
as chiral selectors in capillary eletrophoresys Fresenius J. Anal. Chem., 370, 363 (2001).
45. G.Vecchio, D.La Mendola, E.Rizzarelli, The Synthesis and Conformation of -Cyclodextrins
Functionalized with Enantiomers of Boc-Carnosine J.Supramol.Chem., 1, 87 (2001).
46. D. La Mendola, P. Mineo, E. Rizzarelli, E. Scamporrino, Emilio; G. Vecchio, D. Vitalini,
Copper(II) assisted self-assembly of functionalized -cyclodextrins with -alanyl-L-histidine.
J.Supramol. Chem. 1, 147 (2001).
47. G.Vecchio, D.La Mendola, E.Rizzarelli, S.Sortino SOD-like activity of copper(II) complexes
of -cyclodextrins functionalized with carnosine J.Inorg.Biochem 86, 468 (2001).
48. D.La Mendola, F.Nicoletti, E.Rizzarelli, G.Vecchio Neuroprotection against excitotoxic death
by copper(II) complexes of carnosine and its monofunctionalized cyclodextrin derivative
J.Inorg.Biochem 86, 305 (2001).
49. E. Rizzarelli, G. Vecchio Metal Complexes of functionalized cyclodextrins as enzyme models
and chiral receptors Coord.Chem.Rev. 188, 343-364 (1999).
50. V.Cucinotta, G.Grasso, G.Vecchio From Capped to Three-Dimensional Cyclodextrins: the
First Example of a New Class of Receptors by Trehalose Capping of a -Cyclodextrin
J.Inclusion Phenom. 31, 43 (1998).
51. C.Donze', E.Rizzarelli, G.Vecchio Synthesis and intramolecular inclusion studies of
tryptophan-modified--cyclodextrins J.Inclus.Phenom. 31, 27 (1998).
52. T. Campagna, G. Grasso, E. Rizzarelli, G. Vecchio. L- and D- cysteine derivatives of cyclodextrin: different molecular recognition properties of their copper(II) complexes for
amino acids Inorg. Chim.Acta 275-276, 395 (1998).
53. C. Donzé, E. Rizzarelli, G. Vecchio Intramolecular Inclusion of L-Tryptophan within 3functionalized cyclodextrins Supramol. Chem. 10, 33 (1998).
54. G.Galaverna, R.Corradini, A.Dossena, R.Marchelli, G.Vecchio Histamine-modified cyclodextrins for the enantiomeric separation of DNS-amino acids in capillary
electrophoresis Electrophoresis 18, 905 (1997).
55. R.P.Bonomo, V.Cucinotta, F.D'Alessandro, G.Impellizzeri, G.Maccarrone, E.Rizzarelli,
G.Vecchio, L.Carima, R.Corradini, G.Sartor, R.Marchelli Chiral Recognition by means of the
copper(II) complexes of 6-deoxy-6-N-(2-methylaminopyridine)--cyclodextin Chirality 9, 341
(1997).
56. B.Di Blasio, S.Galdieri, M.Saviani, G.Pedone, E.Benedetti, E.Rizzarelli, S.Pedotti,
G.Vecchio, W.A.Gibbons Synthesis and structural characterization of 6I,6II-Diamino,6I,6IIDideoxy-Cyclomaltoheptaose, a Difunctionalized -Cyclodextrin, Carbohydr. Res. 282, 41
(1996).
57. B.Di Blasio, S.Galdieri, M.Saviano, G.Pedone, G.De Simone, E.Benedetti, R.Deschenaux,
E.Rizzarelli, G.Vecchio, Functionalized Cyclodextrins: Crystal Structure of 6-deoxy-6-4-[2-
(N-tert-butoxycarbonyl)aminoethyl]-imidazolyl-cyclomaltoheptaose, Supramolecular Chem.
7, 47, (1996).
58. R.Bonomo, B.Di Blasio, G.Maccarrone, V.Pavone, C.Pedone, E.Rizzarelli, M.Saviano,
G.Vecchio Crystal And Molecular Structure of Ternary Copper(II) Complex Of 6-Deoxy-6[2-(4-Imidazolyl)Ethylamino]Cyclomaltoheptaose With L-Tryptophan. The Role of Weal
Forces in the Chiral Recognition Process Assisted by a Metallocyclodextrin, Inorg.Chem 35,
4497 (1996).
59. R.Bonomo, S.Pedotti, G.Vecchio, E.Rizzarelli Molecular Recognition of Amino Acids by
Copper(II)
Complexes
of
6A,6X-Diamino-6A,6X-Dideoxy--Cyclodextrin
(X=B;C,D)
Inorg.Chem 35, 6873 (1996).
60. V.Cucinotta, F.D'Alessandro, G.Impellizzeri, G.Maccarrone, E.Rizzarelli and G.Vecchio
Functionalized -cyclodextrins: Thermodynamic and NMR Titration on 6-Diethylentriamine
Derivative J.Chem.Soc., Perkin Trans. II, 1785 (1996).
61. R.P.Bonomo, E.Conte, G.De Guidi, G.Maccarrone, E.Rizzarelli, G.Vecchio Characterization
and Superoxide Dismutase Activity of Copper(II) Complexes of 6-Difunctionalized Cyclodextrins J.Chem.Soc., Dalton Trans 4351 (1996).
62. V.Cucinotta, G.Grasso, S.Pedotti, E.Rizzarelli, G.Vecchio, B.DiBlasio, C.Isernia, M-Saviano,
C.Pedone Platinum(II)-diaminocyclodextrin complex: a crystallographyc and solution study.
Synthesis and structural characterization of platinum(II) complex of 6A,6B-diamino-6A,6Bdideoxy-cyclomaltoheptaose. Inorg.Chem., 35, 7535 (1996).
63. V.Cucinotta, G.Grasso, S. Pedotti, E. Rizzarelli, G.Vecchio Three-dimensional Cyclodextrin:
A new class of hosts by trehalose capping of -cyclodextrin J.Inclusion Phenom., 23, 39
(1996).
64. G.Condorelli, L.L.Costanzo, G.De Guidi, S.Giuffrida, E.Rizzarelli, G.Vecchio Inhibition of
Photohemolysis by Copper(II) Complexes with SOD-like Activity J.Inorg.Biochem., 54, 257
(1994).
65. F.D'Alessandro,
F.G.Gulino,
G.Impellizzeri,
G.Pappalardo,
E.Rizzarelli,
D.Sciotto,
G.Vecchio A New Water Soluble Host Compound Possessing Two Different Hydrophobic
Recognition Cavities: Calix[4]arene Derivative Conjugated with Monofunctionalized Cyclodextrin Tetrahedron Lett., 35, 629 (1994).
66. R.Corradini, A.Dossena, G.Impellizzeri, G.Maccarrone, R.Marchelli, E.Rizzarelli, G.Sartor,
G.Vecchio Chiral Recognition and Separation of Amino Acids by Means of a Copper(II) of
Histamine Monofunctionalized -Cyclodextrin J.Am.Chem.Soc., 116, 10267 (1994).
67. L.L.Costanzo, G.De Guidi, S.Giuffrida, E.Rizzarelli, G.Vecchio Determination of Superoxide
Dismutase-Like Activity of Copper(II) Complexes. Relevance of the Speciation for the Correct
Interpretation of In Vitro O2- Scavenger Activity J.Inorg.Biochem., 50, 273 (1993).
68. R.P.Bonomo, V.Cucinotta, F.D'Alessandro, G.Impellizzeri, G.Maccarrone, E.Rizzarelli,
G.Vecchio
Coordination
Properties
of
6-Deoxy-6-[1-(2-Amino)Ethylamino]-
Cyclomaltoheptaose and the Ability of its Copper(Ii) Complex to Recognize and Separate
Amino Acid Enantiomeric Pairs J.Inclus.Phen.Mol.Rec., 15, 167 (1993).
69. V.Cucinotta, A.Mangano, G.Nobile, A.M.Santoro, G.Vecchio New Platinum(II) Complexes of
-Cyclodextrin Diamine Derivatives and Their Antitumour Activity.J.Inorg.Biochem., 52, 183
(1993).
70. R.P.Bonomo, G.Impellizzeri, G.Pappalardo, E.Rizzarelli, G.Vecchio. Cyclo-L-Histidyl-LHistidyl Capped -Cyclodextrin a New Potentially Enzyme-Mimicking Compound or Artificial
Receptor with Two recognition Sites. Gazzetta Chimica Italiana, 123, 593 (1993).
71. G.Impellizzeri, G. Maccarrone, E. Rizzarelli, G. Vecchio Thermodynamic study of chiral
recognition of amino acids by means of copper(II) complex of histamine monofunctionalized
-cyclodextrin. Calor.Anal. Therm. 24, 269 (1993).
72. V.Cucinotta, F.D'Alessandro, G.Impellizzeri, G.Vecchio Synthesis and Conformation of
Dihistamine of Cyclomaltoheptaose (-Cyclodextrin). Carbohydr. Res., 224, 95 (1992).
73. B.Di Blasio, V. Pavone, F. Nastri, C. Isernia, M. Saviano, C. Pedone, V. Cucinotta, G.
Impellizzeri, E. Rizzarelli, G. Vecchio Novel Conformation for a -Cyclodextrin
Monofunctionalized with a Cyclic Dipeptide. Proc. Natl. Acad. Sci. USA, 89, 7218 (1992).
74. V.Cucinotta, F.D'Alessandro, G.Impellizzeri, G.Vecchio The Copper(II) Complex with the
Imidazole-Bound
Histamine
Derivative
of
-Cyclodextrin as a Powerful Chiral
Discriminating Agent. J. Chem.Soc., Chem. Commun., 1743 (1992).
75. V.Cucinotta, F.D'Alessandro, G.Impellizzeri, G.Pappalardo, E.Rizzarelli, G.Vecchio,
Cyclopeptide Functionalized -Cyclodextrin. a NEW Class of Enzyme Mimicking Compound
with Two Recognition Sites. J. Chem.Soc., Chem. Commun., 293 (1991).
76. R.P.Bonomo, V.Cucinotta, F.D'Alessandro, G.Impellizzeri, G.Maccarrone, G.Vecchio,
E.Rizzarelli, Conformational Features and Coordination Properties of Functionalized
Cyclodextrins. Formation, Stability, and Structure of Proton and Copper(II) Complexes of
Histamine bearing -Cyclodextrin in Aqueous Solution. Inorg. Chem., 30, 2708 (1991).
77. R.Corradini, G.Impellizzeri, G.Maccarrone, R.Marchelli, E.Rizzarelli, G.Vecchio, Molecular
Chiral Recognition Assisted by Metal Ion. Copper(II) Ternary Complexes of Functionalized
-Cyclodextrins and Some Aminoacids in Aqueous Solution. J.Inorg.Biochem., 43, 227
(1991).
78. G.Impellizzeri, G.Maccarrone, E.Rizzarelli,
G.Vecchio,
R.Corradini, M.
Marchelli,
Copper(II) Complex a New Enantioselective Receptor for Aromatic Amino Acids. Angew.
Chem., Int. Ed. Engl. 30, 1348 (1991).
79. R.P.Bonomo, V.Cucinotta, F.D'Alessandro, G.Impellizzeri, G.Maccarrone, G.Vecchio,
E.Rizzarelli Metal Complexes of Functionalized Cyclodextrins as Artificial Enzymes
J.Inorg.Biochem., 36, 279 (1989).
Libri
1. R.P.Bonomo, G. Impellizzeri, D. La Mendola, G. Maccarrone, G. Pappalardo, A. Santoro,
G. Tabbi, G. Vecchio, E. Rizzarelli, Functional mimics of Cu, Zn-superoxide dismutase
enzymes in "Metal-ligand interactions in nano-, micro-, and macro-systems in complex
environments "Eds. N. Russo, D.R. Salahub and M. Witko, Kluwer, Dordrecht, 2003 pag
41-63.
2. V. Cucinotta, A. Giuffrida, G. Grasso, G. Maccarrone, A. Mazzaglia, G. Vecchio, The
interaction of cyclodextrins and hemispherodextrins with pesticides as studied by capillary
electrophoresis. Cyclodextrin: From Basic Research to Market, International Cyclodextrin
Symposium, 10th, Ann Arbor, MI, United States, May 21-24 (2000), 393-398.
3. V. Cucinotta, G. Grasso, G. Maccarrone, A. Mazzaglia, G.Vecchio Inclusion properties,
metal ion coordination ability and analitycal applications of trehalose capped
cyclodextrins Proceding of the 9th International Symposium on Cyclodextrins, Kluwer
Academic Publishers 1998 p 501.
4. V.Cucinotta,
G.Grasso,
S.Pedotti,
E.Rizzarelli,
G.Vecchio
Three-dimensional
Cyclodextrin: A new class of hosts by trehalose capping of -cyclodextrin Proceding of the
8th International Symposium on Cyclodextrins, Kluwer Academic Publishers, 1996
Netherlands pag 81.
5. M.Saviano, B.Di Blasio, V.Pavone, C.Pedone, R.P.Bonomo, G.Maccarrone E.Rizzarelli,
G.Vecchio Conformational investigation of functionalized cyclodextrins: a Ternary
Copper(II) Complex Of histamino Cyclodextrin, Copper(II) and L-Tryptophan. in
Syntheses and Methodologies in Inorganic Chemistry, S.Daolio, E.Tondello, P.A.Vigato
eds., 1995, pag 267.
6. G.Maccarrone, E.Rizzarelli, G.Vecchio Complexing Properties of Functionalized
Cyclodextrins in Syntheses and Methodologies in Inorganic Chemistry, S.Daolio,
E.Tondello, P.A.Vigato eds., Padova, 1994, pag 105.
7. R.P.Bonomo, T.Campagna, G.Vecchio Chiral Recognition of Amino Acids Using
Copper(II) Complexes of the 6A,6B-dideoxy,6A,6B-amino--cyclodextrin in Syntheses and
Methodologies in Inorganic Chemistry, S.Daolio, E.Tondello, P.A.Vigato eds., Padova
1994, pag 457.
8. G.Maccarrone, E.Rizzarelli, G.Vecchio Complessi Metallici ad Attivita' Antiossidante.in
Metalli in Medicina, Societa' Chimica Italiana, pag.49-65.
9. G.Maccarrone, E.Rizzarelli, G.Vecchio Chiral Recognition by Functionalized Cyclodextrin
Metal Complexes in Transition Metals in Supramolecular Chemistry, L.Fabbrizi e A.Poggi
eds., Kluwer Academic Publishers 1994, pag 351.
10. R.P.Bonomo, E.Conte, G.Impellizzeri, G.Maccarrone, E.Rizzarelli, G.Vecchio Complexing
Features of Functionalized -Cyclodextrins Sixth International Symposium on
Cyclodextrins, Coll. Minutes, A.R.Hedges Ed., De Sante, Parigi 1992, p 206.
11. R.P.Bonomo, E.Conte, E.Rizzarelli, G.Vecchio Cu(II) Complexes with Functionalized Cyclodextrins Having
Sod-Like Activity. Metal Ions in Biology
and Medicine, Eds
J.Anastassopoulou, Ph.Collery, J.C. Etienne, Th.Theophanides, John Libbey Eurotext,
Paris 1992, p 91.
12. F.Rossi, L.Zaccaro, B.Di Blasio, V.Pavone, O.Maglio, M.Saviano, C.Pedone, V.Cucinotta,
G.Impellizzeri, E.Rizzarelli, G.Vecchio -Cyclodextrins as Potent Bioactive Peptide
Delivery Systems Peptides 1992, C.H.Schneider e A.N.Eberle Eds., ESCOM Scienze
Publisher B.V, pag. 577.
13. R.Corradini,
G.Impellizzeri,
G.Maccarrone,
R.Marchelli,
E.Rizzarelli,
G.Vecchio
Thermodynamics of Chiral Recognition of Aromatic Amino Acids by Histamine
Functionalized--Cyclodextrin Copper Complex in Aqueous Solution. Chemistry and
Properties of Biomedical Systems. E.Rizzarelli, Th.Theophanides, Eds. Kluwer, Dordrecht,
1991, p 209.
Brevetti
1. E. Rizzarelli, G. Vecchio, G. Lazzarino, A. M. Amorini, F. Bellia Trehalose conjugate with
carnosine having antioxidant activity, stable to enzymic hydrolysis, procedure for its
preparation, and pharmaceutical, cosmetic and nutraceutical compositions that contain it. EP
1860116, 2007.
2. E. Rizzarelli, G.Vecchio, A. Puglisi, D. La Mendola, Preparation of cyclodextrins
functionalized with etodolac as specific site release agents. EP 1860110, 2007.
3. A. M. Amorini, F. Bellia, G. Lazzarino, E. Rizzarelli, G. Vecchio Coniugati di trealosio con
carnosina ad attività antiossidante, stabili all’idrolisi enzimatica. procedimento per la loro
preparazione e composizioni farmaceutiche, Cosmetiche e Nutraceutiche che li contengono
MI2006A000690, 2006.
4. D. La Mendola, E. Rizzarelli, A. Puglisi, G. Vecchio Sintesi di ciclodestrine funzionalizzate
con etodolac come agenti di rilascio sito specifico brevetto MI2006A000894, 2006.
5. D.La Mendola, E.Rizzarelli e G.Vecchio (Universita' di Catania), CARNOSINE derivatives, A
process for the preparation thereof AND pharmaceutical compositions containing them.
EP1176154, 2002.
6. D.La Mendola, E.Rizzarelli e G.Vecchio (Universita' di Catania), .