CHE464 Separation and Purification Processes for Biochemical

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CHE464 Separation and Purification Processes for Biochemical Products
Course Description and Syllabus
Spring 2009- 2010
Instructor:
Dr. Ekrem Ozdemir
Room: Z45
Phone: (232) 750 6685
e-mail: ekremozdemir@iyte.edu.tr
The objective of this course is to analyze chemical and physical processes about how to
separate and purify biochemical products by applying the chemical engineering principles.
Schedule (Tentative):
February 16
February 23
March 02
March 09
March 16
March 23
March 30
April 06
April 13
April 20
April 27
May 04
May 11
May 18
May 25
Coverage
Introduction to Bioseparation
Overview of Cell Biology and Biochemistry
Overview of Cell Biology and Biochemistry-Cont.
Group-A : Filtration
Group-B : Centrifugation and Ultracentrifugation
Group-C : Cell Disruption (Chemical and Mechanical)
Group-D : Extraction
Group-E : Adsorption
Group-F : Chromatography
Group-G : Precipitation
Group-H : Ultrafiltration and Electrophoresis
Group-I : Crystallization
Group-J : Drying
General Review
Final (Take-Home)
Reference Books
Belter, P.A., Cussler, E.L., and Hu, W.S., Bioseparations, John Wiley & Sons, New York, 1988
Weatherley, L.R., Engineering Processes for Bioseparations, Butterworth-Heinemann, 1994
Grading
Presentation
Report
Final (Take-Home)
30%
40%
30%
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