Rui Jiang, PhD
Associate Professor of Pattern Recognition and Bioinformatics
MOE Key Laboratory of Bioinformatics
Phone:
Bioinformatics Division, TNList / Dept of Automation
Fax:
FIT 1-107, Tsinghua University
Email:
Beijing 100084, China
(8610) 62795578
(8610) 62773552
ruijiang@tsinghua.edu.cn
ruijiang@gmail.com
RESEARCH FIELDS
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Identification of genetic risk factors underlying complex diseases. Integrative and systems
biology approaches to the identification of gene-disease and domain-disease associations.
Genome-wide association studies. Bayesian methodology, machine learning approaches,
and high performance computing techniques for genome-wide association studies.
Machine learning. Random Forest, AdaBoost, Boosting, other tree-based ensemble learning
approaches.
EDUCATION BACKGROUND
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Ph. D. in Automatic control engineering, Jan. 2002,
Department of Automation, Tsinghua University, Beijing, P. R. China.
M. S. in Automatic control engineering, Jan. 2002,
Department of Automation, Tsinghua University, Beijing, P. R. China.
B. S. in Automatic control engineering, Sept. 1997,
Department of Automation, Tsinghua University, Beijing, P. R. China.
ACADEMIC EXPERIENCES
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Associate Professor, Jul. 2007~ present
MOE Key Laboratory of Bioinformatics and
Bioinformatics Division, TNList / Department of Automation
Tsinghua University, Beijing, China.
Postdoctoral Research Associate, Jan. 2004 ~ Jun. 2007
Computational Biology and Bioinformatics Program, University of Southern California,
USA.
Postdoctoral Research Associate, Feb. 2002 ~ Dec. 2003
Department of Physics, Hong Kong University of Science and Technology, Hong Kong.
Research Assistant, Sept. 1996 ~ Jan. 2002
Department of Automation, Tsinghua University, Beijing, China.
SELECTED PUBLICATIONS
1. Rui Jiang, Zhidong Tu, Ting Chen, and Fengzhu Sun. Network Identification in Stochastic
Networks. Proc. Natl. Acad. Sci. USA, 103(25):9404~9409, 2006
2. Rui Jiang, Hua Yang, Fengzhu Sun, and Ting Chen. Searching for interpretable rules for
human mutations: A simulated annealing bump hunting strategy, BMC Bioinformatics,
7:417, 2006
3. Rui Jiang, Hua Yang, Linqi Zhou, C.-C. Jay Kuo, Fengzhu Sun, and Ting Chen.
Sequence-based prioritization of nonsynonymous single nucleotide polymorphisms for
study of disease mutations, American Journal of Human Genetics, 81(2):346-360, 2007
4. Xuebing Wu, Rui Jiang, Michael Q. Zhang, Shao Li*, Network-based global inference of
human disease genes, Molecular Systems Biology, 4:189, 2008
5. Wanwan Tang, Xuebing Wu, Rui Jiang*, Yanda Li*, Epistatic module detection for
case-control studies: A Bayesian module with a Gibbs sampling strategy, PLoS Genetics,
5(5): e1000464. doi:10.1371/journal.pgen.1000464, 2009
Xuebing Wu, Qifang Liu, Rui Jiang*, Align human interactome with phenome to identify
causative genes and networks underlying disease families, Bioinformatics, 25(1):98-104,
2009
7. Rui Jiang*, Wanwan Tang, Xuebing Wu, Wenhui Fu, A random forest approach to the
detection of epistatic interactions in case-control studies, BMC Bioinformatics, 10 (Suppl
1):S65, 2009
8. Rui Jiang, Ting Chen, and Fengzhu Sun*. Bayesian models and Gibbs sampling strategies
for local graph alignment and motif finding in stochastic networks, Communications in
Information and Systems, 9(4):347-370, 2009
9. Jianxing Feng, Rui Jiang*, Tao Jiang*, A max-flow based approach to the identification of
protein complexes using protein interaction and microarray data, IEEE Transactions on
Computational Biology and Bioinformatics, in press, 2010
10. Wangshu Zhang, Yong Chen, Rui Jiang*, Comparative study of network-based
prioritizations of human protein domains associated with complex diseases, Fronties in
Electronic Engineering in China, in press, 2010
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