Questions for exam in infectious diseases – 5th year 2008-2009 Part I: Organ-oriented approach and special situations 1. Acute tonsillopharyngitis (sore throat) syndrome 2. Acute epiglottitis, laryngitis and laryngotracheitis 3. Community-acquired pneumonia 4. Purulent meningitis (incl. neonatal age) 5. Aseptic meningitis and encephalitis 6. Acute diarrhoea 7. Skin and musculoskeletal infections of bacterial origin 8. Infectious diseases with maculopapular exanthem 9. Infectious diseases with vesicular and pustular exanthem 10. General overview of liver infections. Parenchymatic infections diffuse and focal, hepatobiliary infections 11. Upper and lower urinary tract infections 12. Infective endocardititis 13. Lymphadenopathy and lymfatic tissue infections 14. Sepsis, septic shock 15. Fever of unknown origin. Diagnostic approach, common causes in temperate climatic zones. 16. Fever in patient returning from tropics 17. Diarrhoea in patient returning from tropics 18. Infectious diseases during pregnancy. Congenital and perinatal infections. 19. Biological weapons, with emphasis on anthrax. 20. Animal bite infections (lyssa, cat-scratch disease). 21. Hospital-acquired infections. Part II : Pathogen-oriented approach 1. Influenza 2. Arboviral infections (tick-borne encephalitis, dengue fever, yellow fever) 3. Epidemic parotitis and enteroviral infections (Coxsackie, ECHO viruses, polioviruses) 4. Herpesviruses infections 5. HIV infection. Routes of infection, classification, clinics, diagnosis, therapy, prognosis. 6. Opportunistic infections in HIV disease. Clinics, diagnosis, therapy, prophylaxis 7. Viral hepatitis A-E 8. Staphylococcal infections. Toxic shock syndrome 9. Streptococcal infections. Toxic shock syndrome 10. Pneumococcal infections 11. Meningococcal invasive disease (incl. pathogenesis) 12. Salmonellosis and campylobacteriosis 13. Shigella and E.coli diarhoea infections 14. Spirochetal infections (esp. Lyme borreliosis, leptospirosis) 15. Chlamydia and Mycoplasma infections 16. Clostridial toxin-mediated diseases (esp. botulism, tetanus) 17. Fungal infections in immunocompetent and immunocompromised patients 18. Amoebiasis, giardiasis 19. Malaria 20. Intestinal helminthiases (intestinal nematodes, cestodes) Part III: Antiinfective therapy 1. Beta-lactam antibiotics. Subgroups, antibacterial spectra, indications, adverse effects, mechanisms of resistance. 2. Penicillins. Drugs, antibacterial spectra, indications, doses, adverse effects. 3. Cephalosporins. Drugs, antibacterial spectra, indications, adverse effects. 4. Macrolides, lincosamides. Drugs, antibacterial spectra, indications, adverse effects. 5. Tetracyclines, chloramphenicol, indications, adverse effects. metronidazol. Drugs, antibacterial spectra, 6. Aminoglycosides and glycopeptides. Drugs, antibacterial spectra, indications, adverse effects. Monitoring of therapy. 7. Fluoroquinolones and cotrimoxazol. Drugs, antibacterial spectra, indications, adverse effects. 8. Antibiotic therapy of Gram-positive infections 9. Antibiotic therapy of Gram-negative infections 10. Antibiotic therapy of anaerobic infections 11. Antibiotic therapy of nosocomial infections (resistant bacteria) 12. Chemotherapy of fungal infections. Drugs, indications 13. Chemotherapy of viral infections. Indications, drugs 14. Hyperimmune specific immunoglobulins as part of complex therapy of infections 15. Physiological human microbial flora and its changes due to antibiotics (incl. antibiotic - associated colitis).