Questions for exam in infectious diseases – 5th year 2008-2009
Part I: Organ-oriented approach and special situations
1. Acute tonsillopharyngitis (sore throat) syndrome
2. Acute epiglottitis, laryngitis and laryngotracheitis
3. Community-acquired pneumonia
4. Purulent meningitis (incl. neonatal age)
5. Aseptic meningitis and encephalitis
6. Acute diarrhoea
7. Skin and musculoskeletal infections of bacterial origin
8. Infectious diseases with maculopapular exanthem
9. Infectious diseases with vesicular and pustular exanthem
10. General overview of liver infections. Parenchymatic infections diffuse and focal,
hepatobiliary infections
11. Upper and lower urinary tract infections
12. Infective endocardititis
13. Lymphadenopathy and lymfatic tissue infections
14. Sepsis, septic shock
15. Fever of unknown origin. Diagnostic approach, common causes in temperate climatic
zones.
16. Fever in patient returning from tropics
17. Diarrhoea in patient returning from tropics
18. Infectious diseases during pregnancy. Congenital and perinatal infections.
19. Biological weapons, with emphasis on anthrax.
20. Animal bite infections (lyssa, cat-scratch disease).
21. Hospital-acquired infections.
Part II :
Pathogen-oriented approach
1. Influenza
2. Arboviral infections (tick-borne encephalitis, dengue fever, yellow fever)
3. Epidemic parotitis and enteroviral infections (Coxsackie, ECHO viruses, polioviruses)
4. Herpesviruses infections
5. HIV infection. Routes of infection, classification, clinics, diagnosis, therapy, prognosis.
6. Opportunistic infections in HIV disease. Clinics, diagnosis, therapy, prophylaxis
7. Viral hepatitis A-E
8. Staphylococcal infections. Toxic shock syndrome
9. Streptococcal infections. Toxic shock syndrome
10. Pneumococcal infections
11. Meningococcal invasive disease (incl. pathogenesis)
12. Salmonellosis and campylobacteriosis
13. Shigella and E.coli diarhoea infections
14. Spirochetal infections (esp. Lyme borreliosis, leptospirosis)
15. Chlamydia and Mycoplasma infections
16. Clostridial toxin-mediated diseases (esp. botulism, tetanus)
17. Fungal infections in immunocompetent and immunocompromised patients
18. Amoebiasis, giardiasis
19. Malaria
20. Intestinal helminthiases (intestinal nematodes, cestodes)
Part III: Antiinfective therapy
1. Beta-lactam antibiotics. Subgroups, antibacterial spectra, indications, adverse effects,
mechanisms of resistance.
2. Penicillins. Drugs, antibacterial spectra, indications, doses, adverse effects.
3. Cephalosporins. Drugs, antibacterial spectra, indications, adverse effects.
4. Macrolides, lincosamides. Drugs, antibacterial spectra, indications, adverse effects.
5. Tetracyclines, chloramphenicol,
indications, adverse effects.
metronidazol.
Drugs,
antibacterial
spectra,
6. Aminoglycosides and glycopeptides. Drugs, antibacterial spectra, indications, adverse
effects. Monitoring of therapy.
7. Fluoroquinolones and cotrimoxazol. Drugs, antibacterial spectra, indications, adverse
effects.
8. Antibiotic therapy of Gram-positive infections
9. Antibiotic therapy of Gram-negative infections
10. Antibiotic therapy of anaerobic infections
11. Antibiotic therapy of nosocomial infections (resistant bacteria)
12. Chemotherapy of fungal infections. Drugs, indications
13. Chemotherapy of viral infections. Indications, drugs
14. Hyperimmune specific immunoglobulins as part of complex therapy of infections
15. Physiological human microbial flora and its changes due to antibiotics (incl. antibiotic
- associated colitis).