Conference Faculty - School of Medicine

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Welcome to
19th Annual Cleveland Review of
Rheumatic Diseases
April 9-10, 2010
The Ritz-Carlton, Cleveland
Announcements
Evaluation Form: Please complete the Course Evaluation Form and return it at
the conclusion of the course. We appreciate your comments and find them
useful for future planning.
Category 1 Credits/Certificate of Attendance: Please complete the Credit
Claim Form(s) included with your registration materials and return the yellow
copy at the conclusion of the conference. The white copy is your Category 1
credit certificate. This is the only certificate you will receive for this symposium.
Outcomes
We are interested in assessing the outcomes of our program and we are asking
for your help. Please complete the “Commitment to Change” form included with
your registration materials and return it to the registration desk at the conclusion
of the conference. You will be contacted by email for follow up. Your responses
will remain confidential.
For Further Information
Contact the CME Program
10524 Euclid Avenue
Cleveland, OH 44106-6026
Tel: (216) 983-1239 Fax: (216) 844-8133
Email: [email protected]
http://casemed.case.edu/cme
Conference Faculty
Ali Askari, MD
Course Director
Professor of Medicine
Case Western Reserve University School of Medicine
Chief, Division of Rheumatology
University Hospitals Case Medical Center
Dr. Askari reports no financial relationship with a commercial interest.
Rebecca Burns, MD
Fellow
Division of Rheumatology
University Hospitals Case Medical Center
Dr. Burns reports no financial relationship relevant to this presentation.
Raphaela Goldbach-Mansky, MD
Acting Chief, Translational Autoinflammatory Disease Section
National Institute of Arthritis & Musculoskeletal Diseases
Dr. Goldbach-Mansky reports no financial relationship with a commercial interest. Presentation
will include discussion of unlabeled/investigational uses of a commercial product.
Mark Gourley, MD
Director, Clinical Care and Training
National Institute of Arthritis & Musculoskeletal Diseases
Dr. Gourley reports no financial relationship with a commercial interest.
Salim Hayek, MD, PhD
Associate Professor of Anesthesiology
Case Western Reserve University School of Medicine
Chief, Division of Pain Medicine
University Hospitals Case Medical Center
Dr. Hayek receives grant/research support from Endo Pharmaceuticals, Medtronic, Boston
Scientific and St. Jude Medical; is a consultant for Boston Scientific and Medtronic; and is on the
speaker’s bureau of Pfizer and Pricara. Presentation will include discussion of
unlabeled/investigational uses of a commercial product.
Paula Jofre, MD
Fellow
Division of Rheumatology
University Hospitals Case Medical Center
Dr. Jofre reports no financial relationship with a commercial interest.
Joel Kremer, MD
Pfaff Family Professor of Medicine
Albany Medical College
Director of Research
The Center for Rheumatology
Dr. Kremer receives grant/research support from and is a consultant for Bristol-Myers Squibb,
Roche, Genentech, Ortho-Biotech and Pfizer. Presentation will include discussion of
unlabeled/investigational uses of a commercial product.
Michelle Petri, MD, MPH
Professor of Medicine
Division of Rheumatic Diseases
Johns Hopkins University
Co-Director, Hopkins Lupus Pregnancy Center
Dr. Petri receives grant/research support from and/or is a consultant for HGS, MedImmune, UCB
and Pfizer (all support goes to Johns Hopkins). Presentation will include discussion of
unlabeled/investigational uses of a commercial product.
Christopher Ritchlin, MD, MPH
Professor of Medicine
Director, Clinical Immunology Research Unit
University of Rochester School of Medicine and Dentistry
Dr. Richlin receives grant/research support from Amgen, Bristol-Myers Squibb, Centocor, UCB
and Wyeth, and is a consultant for Abbott, Amgen, Bristol-Myers Squibb, Roche, Wyeth, UCB,
Centocor and Pfizer. Presentation will include discussion of unlabeled/investigational uses of a
commercial product.
Naomi Schlesinger, MD
Associate Professor of Medicine
Chief, Division of Rheumatology & Connective Tissue Research
University of Medicine and Dentistry of New Jersey
Robert Wood Johnson Medical School
Dr. Schlesinger receives grant/research support from and is a consultant for Novartis; is on the
speaker’s bureau of Takeda; and is on the advisory board of Takeda, Enzyme Rx, Savent,
Novartis and URL Pharma. Presentation will include discussion of unlabeled/investigational uses
of a commercial product.
John Shaffer, MD
Professor of Orthopaedic Surgery
Case Western Reserve University School of Medicine
Department of Orthopaedics
University Hospitals Case Medical Center
Dr. Shaffer reports no financial relationship with a commercial interest.
Alexandra Villa-Forte, MD
Center for Vasculitis Care and Research
Department of Rheumatic and Immunologic Diseases
Cleveland Clinic
Dr. Villa-Forte reports no financial relationship with a commercial interest.
Rachel Waldman, MD
Chief Fellow
Division of Rheumatology
University Hospitals Case Medical Center
Dr. Waldman reports no financial relationship with a commercial interest.
Michael Weingarten, MD
Fellow
Division of Rheumatology
University Hospitals Case Medical Center
Dr. Weingarten reports no financial relationship with a commercial interest.
Yusuf Yazici, MD
Assistant Professor of Medicine
Division of Rheumatology
Hospital for Joint Diseases & Medicine
NYU Medical Center
Dr. Yazici receives grant/research support from Centocor; is a consultant for Bristol-Myers
Squibb, Celgene, Genentech, Centocor and UCB; and is on the speaker’s bureau of BristolMyers Squibb and Genentech. Presentation will include discussion of a unlabeled/investigational
uses of a commercial product.
Planning Committee
Ali Askari, MD
Dr. Askari reports no financial relationship with a commercial interest.
Donald Anthony, Jr., MD, PhD
Dr. Anthony reports no financial relationship with a commercial interest.
Douglas Flagg, MD
Dr. Flagg’s spouse/partner receives grant/research support from GlaxoSmithKline and
AstraZeneca; and is a consultant for Cognition Group Biosource and United E-Pharma Solution.
Lawrence Kent, MD
Dr. Kent reports no financial relationship with a commercial interest.
Charles Malemud, PhD
Dr. Malemud reports no financial relationship with a commercial interest.
Roland Moskowitz, MD
Dr. Moskowitz is a consultant for Cypress Bio, Novartis, Nocox and Horizon Therapeutics; and is
on the speakers bureau of Pfizer.
Mathilde Pioro, MD
Dr. Pioro’s spouse/partner is a consultant for Avanir Pharmaceuticals.
Cleveland Society of Rheumatology Officers
Douglas Flagg, MD
President
Rochelle Rosian, MD
President-Elect
Mathilde Pioro, MD
Secretary
Abby Goulder-Abelson, MD
Past President
Disclosure Policy
The policy of Case Western Reserve University School of Medicine CME
Program requires that the Activity Director, planning committee members and all
activity faculty (that is, anyone in a position to control the content of the education
activity) disclose to the activity participants all relevant financial relationships with
commercial interests. Disclosure will be made to activity participants prior to the
commencement of the activity. Case Western Reserve University School of
Medicine also requires that faculty make clinical recommendations based on the
best available scientific evidence and that faculty identify any discussion of “offlabel” or investigational use of pharmaceutical products or medical devices.
The intent of this policy is not to prevent a presenter with a potential conflict of
interest from making a presentation. It is the right of the audience to know about
any such potential conflict of interest which should be openly identified.
Members of the audience may form their own judgments and it is incumbent
upon each listener to determine whether a presenter’s outside interests may
reflect a possible bias in either the exposition or the conclusions presented.
Detailed disclosures are made in the Faculty section of this publication.
Presenters are also obligated to disclose any discussion of unlabeled or
unapproved uses of drugs or devices.
Learning Objectives
After attending this program, participants will be able to:
 Develop strategies for managing patients with rheumatoid arthritis and
related arthritis at every stage of the disease.
 Identify selected treatment modalities for rheumatic disease and
enumerate how these new advances may impact the practice of
rheumatology.
 Identify patients who are at the stage of their disease where stem cell
transplant may be beneficial.
Continuing Education
Physicians
Case Western Reserve University School of Medicine is accredited by the
Accreditation Council for Continuing Medical Education to provide continuing
medical education for physicians.
Case Western Reserve University School of Medicine designates this [learning
format*] for a maximum of 11 AMA PRA Category 1 CreditsTM. Physicians
should claim only the credit commensurate with the extent of their participation in
the activity.
*learning format = live activity, enduring material, journal-based CME activity,
test-item writing activity, manuscript review activity, performance improvement
(PI) CME activity or internet point-of-care activity
Nurses
The American Nurses Credentialing Center (ANCC) accepts AMA PRA Category
1 Credit TM toward recertification requirements.
Medical Disclaimer
Medicine is an ever-changing science. As new research and clinical experience
broaden our knowledge, changes in treatment and drug therapy are required.
The authors have checked with sources believed to be reliable in their efforts to
provide information that is complete and generally in accord with the standards
accepted at the time of publication.
Although every effort is made to ensure that this material is accurate and up-todate, it is provided for the convenience of the user and should not be considered
definitive. Since medicine is an ever-changing science, neither the authors nor
the Case Western Reserve School of Medicine nor any other party who has been
involved in the preparation or publication of this work warrants that the
information contained herein is in every respect accurate or complete, and they
are not responsible for any errors or omissions or for the results obtained from
the use of such information.
Readers are encouraged to confirm the information contained herein with other
sources. This information should not be construed as personal medical advice
and is not intended to replace medical advice offered by physicians. The Case
School of Medicine will not be liable for any direct, indirect, consequential,
special, exemplary, or other damages arising therefrom.
Acknowledgments
Educational grants from the following companies in support
of this conference is gratefully acknowledged
Abbott
Amgen
Centocor Ortho Biotech Services
Genentech
UCB, Inc.
Exhibits provided by
Abbott ♦ Amgen-Pfizer ♦ Bristol-Myers Squibb
Centocor Ortho Biotech Inc. ♦ Forest Pharmaceuticals
Genentech ♦ Genentech/Bioden-Idec
Lilly ♦ Pfizer Inc. ♦ UCB, Inc.
Acceptance of funding in support of this program does not constitute
endorsement of any product or manufacturer
Program Agenda
Friday, April 9
7:30am
Registration and Continental Breakfast
8:15-8:30
Welcome and Introduction
Ali Askari, MD, Course Director
Douglas Flagg, MD, President, Cleveland Society of
Rheumatology
8:30-8:45
Case Presentation of Vasculitis
Paula Jofre, MD
8:45-9:30
Vasculitis: Progress and Controversies
Alexandra Villa-Forte, MD
9:30-9:45
Case Presentation of Lupus
Rebecca Burns, MD
9:45-10:30
Choices of Treatment for Lupus
Michelle Petri, MD, MPH
10:30-10:45
Break
10:45-11:00
Case Presentation of Antiphospholipid Syndrome
Rachel Waldman, MD
11:00-11:45
Choices of Treatment for Antiphospholipid Syndromes
Michelle Petri, MD, MPH
11:45-1:00pm
Lunch
1:00-1:50
Autoinflammatory Diseases (including TRAPS)
Raphaela Goldbach-Mansky, MD
1:50-2:05
Case Presentation of Behcet’s Disease
Rachel Waldman, MD
2:05-2:50
Behcet’s Disease
Yusuf Yazici, MD
2:50-3:00
Break
3:00-3:15
Case Presentation of Rheumatoid Arthritis
Paula Jofre, MD
3:15–4:00
Rheumatoid Arthritis
Joel Kremer, MD
4:00–4:15
Case Presentation of Spondyloarthropathies
Michael Weingarten, MD
4:15–5:00
Choices of Treatment for Spondyloarthropathies
Christopher Ritchlin, MD, MPH
5:00
Adjourn for the day
Program Agenda
Saturday, April 10
7:30-8:00am
Registration and Continental Breakfast
8:00-8:05
Opening Remarks
Ali Askari, MD
8:05-8:20
Case Presentation of Myopathies
Rachel Waldman, MD
8:20-9:05
Myopathies
Mark Gourley, MD
9:05-9:20
Case Presentation of Gout
Michael Weingarten, MD
9:20-10:05
Choices for Treatment of Gout
Naomi Schlesinger, MD
10:05-10:30
Break
10:30-11:15
Pain Management
Salim Hayek, MD, PhD
11:15-11:30
Case Presentation of AVN
John Shaffer, MD
11:30-12:15pm
AVN of the Bone
John Shaffer, MD
12:15
Adjournment
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