SCIENTIFIC PUBLICATIONS A. BOOKS AND MONOGRAPHS Papa MZ, Adar R. Another look at Buerger’s disease. In: H. Boccalon, Ed. Vascular Medicine (Proc. of 16th World Congress of International Union of Angiology). Excerpta Medica 1993, pp. 113-116. _____________________________________________________________________ 2. Hughes KS, Papa MZ, Whitney T, McLellan R : prophylactic mastectomy and Inherited cancer predisposition, in: Shaw GL ed. Cancer genetics for the clinician. Plenum Publishing Corp. New York , 2000. 1. Papa MZ. Sadetzki S, Regional Breast Cancer Treatment. Accepted Feb 2006 –Regional Cancer Therapy. 3. B.1. Articles Published 1. Orda R, Wiznitzer T, Papa MZ, Zolti P. Does appendectomy predispose to inguinal hernia? Am Surg 1974;40:349-351. 2. Bar-Meir S, Papa MZ. Antitrypsin deficiency associated with liver cirrhosis. Harefuah 1975;88:288-289. 3. Bar-Meir S, Papa MZ. Liver damage following salicylate intake. Harefuah 1975;88:247. 4. Schneiderman J, Papa MZ, Adar R. Fresh human umbilical vein for acute animal experiments. Vasc Surg 1978;12(5):306-307. 5. Papa MZ, Klein E, Adar R. Pancreatic abscess. Harefuah 1978;95(5,6):148. 6. Halpern A, Papa MZ, Adar R, Neuman G. Palliative surgery for pancreatic carcinoma. Harefuah 1979;96(10):560. 7. Papa MZ, Halpern Z, Adar R. Vascular surgical infections. Isr J Med Sci 1981;17:257-259. 8. Papa MZ, Halpern Z, Bar-Meir S. Interferon in chronic active hepatits. Harefuah 1981;101:27-28. 9. Adar R, Papa MZ. Impotence in diabetic patients. (Letter to Ed.). Bri Med J 1981;282:312. 10. Mozes M, Papa MZ, Karasik A, Reshef A, Adar R. The role of infection in postmastectomy lymphedema. Surg Ann 1982;14:73-83. 11. Adar R, Papa MZ, Mozes E. Sensitivity to colagen in Thromboangiitis Obliterans. N Engl J Med 1983;309:857-858. 12. Reshef A, Papa MZ, Halpern Z, Lapidot M, Karasik A, Mozes M. Post mastectomy lymphedema. Harefuah 1983;104:41-43. 13. Jacob E, Papa MZ. Cimetidine induced renal transplant rejection. Isr J Med Sci 1983;19:161-164. 14. Bass A, Papa MZ, Morag B, Adar R. Aortic false aneurysm following blunt trauma of the abdomen. J Trauma 1983;23:1072-1073. 15. Adar R, Papa MZ, Halpern Z, Mozes M, Shoshan S, Mozes E. Cellular sensitivity to collagen in Buerger’s disease. N Engl J Med 1983;308(19):1113-1116. 16. Papa MZ, Halpern Z, Rubinstein E, Orenstein A, Gafin S, Adar R. The effect of ischemia of the dog’s colon on transmural migration of bacteria and endotoxin. J Surg Res 1983;35:264-269. 17. Papa MZ, Bass A, Siegel Y, Adar R. Cutaneous complications of coumadin treatment. Harefuah 1983;104:511-512. 18. Adar R, Papa MZ. The definition of Buerger’s disease. World J Surg 1984;8:423. 19. Papa MZ, Amsterdam E, Schneiderman J, Adar R. Hemorrhagic complications encountered in a surgical service. A seven-year survey including unusual presentation. Am J Surg 1984;197:378-381. 20. Mozes M, Horoshowsky H, Bass A, Papa MZ. Iliopsoas injury. Harefuah 1984;106:396398. 21. Papa MZ, Amsalem Y, Bass A, Mozes M, Adar R. Peripheral nerve section as palliation for severe ischemic foot pain. J Cardiovasc Surg 1984;25:115-117. 22. Adar R, Bass A, Nussimovitz M, Papa MZ, Schneiderman J. Angiographic anatomy of the LFCA and preliminary experience with itreconstruction during profundoplasty. Vasc Surg 1984;18:154-164. 23. Keller S, Papa MZ, Wilder JR. Vena Cava interruption. The Mount Sinai Medical Journal 1985;52:353-357. 24. Adar R, Rabi I, Bass A, Papa MZ. Left renal vein ligation in abdominal aortic aneurysm operations: Effects on renal function. Arch Surg 1985;120(9):1033-1036. 25. Adar R, Papa MZ, Amsterdam E, Schneiderman J. Antithrombosis routines and hemorrhagic complications: A seven-year survey comparing vascular and general surgical operations. J Cardiovasc Surg 1985;26:275-279. 26. Yehoshua NM, Papa MZ, Margaliot SZ. Portable air mobile life support unit. Aviation, Space and Environmental Medicine 1985;56(6):598-600. 27. Mozes M, Papa MZ, Zweig A, Adar R. Iliopsoas injury in soccer players. Br J Sports Med 1985;19(3):168-170. 28. Schanzer H, Papa MZ, Miller C. Rupture of a thrombosed abdominal aortic aneurysm. Vasc Surg 1985;2:278-280. 29. Papa MZ, Mule JJ, Rosenberg SA. The anti-tumor efficacy of lymphokine-activated killer cells and recombinant IL-2 in vivo: Successful immunotherapy of established pulmonary metastases from weakly and non-immunogenic murine tumors of three distinct histologic types. Cancer Res 1986;46:4973-4978. 30. Bar-Meir S, Bar-Tal L, Papa MZ, Peled Y. Bromsulfaphtalein clearance and aminopyrine test in patients with Gelbert’s syndrome. Isr J Med Sci 1986;22:376-379. 31. Papa MZ, Vetto JT, Ettinghausen SE, Mule JJ, Rosenberg SA. Effect of corticosteroids on the anti-tumor activity of lymphokine activated killer cells and interleukin-2 in mice. Cancer Res 1986;46:5618-5623. 32. Papa MZ, Shiloni E, McDonald H. Total colonic necrosis, a catastrophic complication of systemic lupus erythematosus. Dis Colon and Rectum 1986;29:576-578. 33. Papa MZ, Drori Y, Bass A, Adar. Cardiovascular changes after upper dorsal sympathectomy: Short and long term effects. Ann Surg 1986;204:715-718. 34. Vetto JT, Papa MZ, Lotze MT, Chang AE, Rosenberg SA. Reduction of toxicity of interleukin-2 and lymphokine activated killer cells in humans by the administration of corticosteroids. J Clin Oncol 1987;5(3):496-503. 35. Papa MZ, Vetto JT, Shiloni E, Eisenthal A, Rosenberg SA. Combined effects of chemotherapy and interleukin-2 in the therapy of mice with advanced pulmonary tumors. Cancer Res 1987;48:122-129. 36. Denicoff KD, Rubinau DR, Papa MZ, Simpson C, Rosenstein D, Rosenberg SA. The neuropsychiatric effects of IL-2 and lymphokine activated killer cell treatment. Ann Int Med 1987;107:293-300. 37. Leffor AA, Hughes KS, Shiloni E, Steinberg SM, Vetto JT, Papa MZ, Sugarbaker PH, Chang AE. Staging of patients with suspected colorectal liver metastases. Current Surg 1987;44(4):308-310. 38. Leffor AA, Hughes KS, Shiloni E, Papa MZ, Sugarbaker P. Intra-abdominal extrahepatic disease in patients with colorectal hepatic metastases. Dis Colon Rectum 1988;31:100-103. 39. Langer JL, Wesson DER, Ein SH, Filler RM, Shandling B, Superina M, Papa MZ. Feeding gastostomy in neurologically impaired children is an antireflux procedure necessary. J Pediatric Gastroenterol & Nutr 1988;7(6):837-841. 40. Papa MZ, Shiloni E, Vetto JT, McDonald H. Surgical complications in patients with SLE. Am J Surg 1989;157:299-303. 41. Papa MZ, Langer JL, Hoffman M, Filler RM. Colonic perforation in cyclic neutropenia. J Pediat Surg 1990;25:346-348. 42. Kashtan H, Papa MZ, Wilson BC, Deutch AA, Hartley SS. Use of photodynamic therapy in the palliation of massive advanced rectal cancer. Dis Colon Rectum 1991;34:600-605. 43. Kashtan H, Papa MZ, Stern HS. Is age an independent variable in the morbidity and mortality of patients with colorectal cancer? A prospective study. Can J Surg 1991;34:374376. 44. Gallinger S, Papa MZ, Reilly MR, et al. Comparative biodistribution and anti- bodydependent cellular cytotoxicity of native and heavy chain chimeric antibody. Mol Biother 1991;3:197-203. 45. Papa MZ, Adar R. A critical look at Thromboangiitis Obliterans (Buerger’s disease). Perspectives in Vasc Surg 1992;5:1-21. 46. Papa MZ, Bass A, Adar R, Halperin Z, Schneiderman J, Becker CG, Brautbar H, Mozes E. Autoimmune mechanisms in Thromboangiitis Obliterans (Buerger’s disease): The role of tobacco antigen and the major histocompatibility complex. Surgery 1992;111:527-531. 47. Stern H, Reilly R, Gallinger S, Kirsch J, DeAngelis C, Papa MZ, Hay K, Schmocker B. Radioimmunodetection of colorectal cancer metastases with 1-131 labelled monoclonal antibody B72.3. A pilot study to determine efficacy of detection and pharmacokinetics. Cancer Investigation 1993;11:129-134. 48. Papa MZ, Adar R. Another look at Buerger’s disease. In: Boccalon H (ed.). Vascular Medicine. Proceedings of the 16th World Congress of the International Union of Angiology, Paris, 1992. Exerpta Medica, Amsterdam, London, New York. Elsevier, 1993, pp. 113-116. 49. Kanety H, Madjar Y, Dagan Y, Levi J, Papa MZ, Pariente C, Goldwasser B, Karasi, A. Serum insulin-like growth factor-binding - 2 (IBFBP-2) is increased and IGFBP-3 is decreased in patients with prostate cancer. Correlation with serum prostate specific antigen. J Clin Endoc Metabol 1993;77:229-233. 50. Feinstein R, Kanety H, Papa MZ, Lunenfeld B, Karasik A. Tumor necrosis factor suppresses insulin induced tyrosine phosphorilation of insulin receptor and its substracts. JBC 1993;268:26055-26058. 51. Papa MZ, Shinfeld A, Klein E, Greif F, Ben-Ari G. Cardiac metastasis of liposarcoma. J Surg Oncol 1994;55(2):132-134. 52. Klein E, Berkenstat G, Koller M, Papa MZ, Ben-Ari G, Liberman N, Perel A. Hemodynamic effects of total abdominal perfusion and stopflow. J Reg Chemother 1994;2:82-85. 53. Kanety H, Finestein R, Papa MZ, Weiss H, Lunenfeld B, Karasik A. TNF suppress insulin induced tyrosine phosphofilation of IRS-1 through increasing serine/threonine phosphorilation of the substrate. JBC 1995;270:23780-23784. 54. Berkovitz L, Papa MZ, Degani H. Effect of tumor necrosis factor on energetics and glucose metabolism of human breast cancer cells. Proceedings of The Society of Magnetic Resonance 1995;3:1697. 55. Lynn M, Klein E, Horowitz A, Kariv N, Papa MZ, Karni T, Ben-Ari G. Effects of stopflow ischemia, regional chemotherapy and reperfusion on healing of bowel anastomosis in the rat. Reg Cancer Treatment 1996;8:82-85. 56. Klein E, Ben-Ari G, Papa MZ, Adar A, Bass A. Vasculr complications of total abdominal perfusion and aortic stop-flow infusion. J Surg Oncol 1996;61:17-19. 57. Papa MZ, Klein E, Karni T, Koller M, Azizi E, Ben-Ari G.. Isolated perfusion with Cisplatinum for the treatment of malignant melanoma of the limbs. AM J Surg 1996;171:416-420. 58. Papa MZ, Davidson B, Karni T, Kline E, Klein E, Sperber F, Koler M, Lynn M, Ben Ari G. The effect of anasthesia type on the needle localization biopsy - another point of view. Am J Surg 1996;171:242-243. 59. Papa MZ, Adar R. A proposed point scoring system for the clinical diagnosis of Buerger’s disease. Eur J Vasc Surg 1996;2:335-339. 60. Kanety H, Hemi R, Papa MZ, Karasik A. Sphingomyelinase and ceramide suppress insulin-induced tyrosine phosphorylation of the insulin receptor substrate-1. JBC 1996;17:9895-9897 61. Bogin L, Papa MZ, Polak-Sharcon S, Degani H. NMR kinetic studies of choline transport and CTP: Phosphocholine cytodylytranseras (CT) activity in TNF--treated human breast cancer cells. Proc Inter Soc for Magnetic Resonance in Medicine 1996;2:1139. 65. Oren R, Dotan I, Papa MZ, Halperin Z. Inhibition of experimentally induced liver cirrhosis in rats by hypothyroidism. Hepatology 24 (2) 419 - 423 1996. 63. Modan B, Gak E, Bar-Sade R, Baruchin R, Hirsh G, Yehezkel G, Theodore L, Lubin F, Ben-Baruch G, Papa MZ, Friedman E. High frequency of BRCA1 185delAG mutation in ovarian cancer in Israel. JAMA: 276; 1823 - 1825, 1996. 64. Papa MZ, Koller M, Klein E, Sarely M, Ben-Ari G. Prostatic cancer presenting as a rectal mass. A surgical pitfall. Brit J Surg, 84; 69-70 1997. 65. Papa MZ, Karni T, Klein E, Killer M, Zippel D, Bersuk D, Ben Ari GY. Avoiding diarrhea after subtotal colectomy for colonic cancer. J AmColl Surgeons : 184; 269 - 272 ,1997. 66. Adar R. Papa MZ. Buerger Disease Eur. J Endovasc Surg. 14. 322. 1997 67. Papa MZ, Bersuk D, Koller M, Klein E, Ben Ari G. The use of “Sentinile lymph node” in breast and melanoma surgery. Harefuah, 133: 428-430. 1997. 68. Zippel D, Klein ES, Davidson B, Mintz Y, Sarely M, Papa MZ, Ben Ari GY. Continuous hyeprtermic peritoneal perfusion for malignant ascites and irresectable intraabdominal cancer. Hyperthermic Oncology, 2: 3-7:1996. __________________________________________________________________ 69. Theodor L. , Bar Sade R. , Kruglikova A. , Ben Baruch G. , Risel S., Hirsch G. , Modan B. , Papa MZ. , Rechavi G. , Friedman E. An identical novel mutation in BRCA 1 and common haplotype in familial ovarian cancer in non - Ashkenazi Jews. Br. Jr. Cancer 77(11) 1880-1884. 1998. 70. Bar Sade R. Kruglikova A. Modan B. Gak E. Yechezkel G. Theodor L. Novikov I. Risel S. Papa MZ . Ben Baruch G and Friedman Eithan. The 185delAG BRCA1 mutation originated before the dispersion of Jews in the diaspora and is not limited to Ashkenazim. Hum Molec. Genetics 7(5) 801-805. 1998. 71. Koller M, Barsuk D, Klien E, Ben Ari G & Papa MZ. Sentinel lymph node Biopsy - a predictor for axillary involvement with breast cancer – has the time come? Eurpean J of Surgical Oncology, 24(3)166-168. 1998. 72. .Theodor L. , Sverdlov R. , Hirsh G. , Bar Sade R. , Gack E. Friedman E. , Kruglova A., Ben Baruch G., Riezel S., Papa MZ. , Goldman B., Friedman E. The experience of the oncogenetic unit in genetic consultation and diagnosis to women who are in high risk for breast and ovarian cancer. Harefuah 134:593-599. 1998 73. Bruck R. Oren R. Shirin H. Abeed H. Papa MZ. Mates Z. Zaidel L. Avni Y. Halpern Z. Hypothyroidism minimizes liver damage and improves survival in rats with thiocetamide induced fulminant hepatic failure. Hepatology 27: 1013-1020 : 1998. 74. Zvibel E. Brill S., Halpern Z.. & Papa M.Z Hepatocyte - extracellular matrix modulates expression of growth factors and growth factor receptors in liver colonizing colon cancer cells Exp. Cell Res. 245:123-131, 1998. 75. Zvibel I. Halpern Z. & Papa MZ. Extracellular matrix modulates expression of growth factors and groes factor receptors in liver-colonizing colon cancer cell line . Int. J. Cancer. 77:295-301, 1998. 76. Koller M. , Papa MZ. , Zwieg A. , Ben Ari G. Spontaneous leak and transection of permanent subclavian catheters. J. of Surg Oncology. 68:166-168,1998. 77. Shiloh S, Petel Y, Papa MZ, Goldman B. Motivations, perceptions and interpersonal differences associated with interest in genetic testing for breast cancer susceptibility among women at high and average risk. Psychology and Health, 13:1071-1086 :1998 78. Bogin L. , Papa MZ. , Polack-Charcon S, Degani H. TNF- induces modulation of Phospholipid metabolism in human breast cancer cells. Biochem- Biophys- Acta 15: 1392(2-3): 217-232: 1998. 79. Papa MZ, Zippel D, Koller M. Klein E,Chetrit A., Ben-Ari G. positive margins of Breast Biopsy :is reexcision always nesessary? Jr. Surg Onc 70 :167-171, 1999. 80. Patel Y. Figer A. Gershoni Baruch R. Papa MZ., Risel S. Chen R. Karasik A. Theodor L and Friedman E. Common origin of the I1307K APC polymorphsim in Ashkenzi and non Ashkenazi Jews Acc. Eur J. Human. Genetics Feb 1999. 81. Shirin H, Dotan I, Papa MZ, Maaravi Y, Aeed H, Zaidel L, Mates Z, Bruck R, Halpern Z. Oren R. Inhibition of conconvalin A-induced acute T-cell dependent hepatic damage in mice by hypothyroidism. Liver. 19:206-211:1999. 82. Bruck R. Frenkel D. Shirin H. Aeed H. Frenkel D. Mates Z. Papa MZ. Zaidel Avni Y. Oren R. & Halpern Z. Hypothyroidisim protects rat liver from acetaminophen hepatotoxicity. Digestive Disease & Sciences. 44. 1228-1235:1999. 83. Hughe K. Papa MZ, Whitney T. , McLellan R. Prophylactic mastectomy and Inherited Predisposition to Breast Carcinoma. Cancer 86: Supp.(8) 1682-1695: 1999, 84. Zvibel I. Mintz Y. Brill S. Halpren Z.& Papa MZ. The role of the liver environment in the regulation of colon cancer metastases. JIMA.2: 48-51: 2000. 85. Adar R. Papa MZ. Schniderman J. Thromangiitis Obliterans: an old disease in need of a new look. Internat. Jr. Cardiology 1: s167-169:2000. 86. Zvibel I, Brill S, Halpern Z, Papa MZ Amphiregulin and and hepatocyte-derived extracellular matrix regulate proliferation and autocrine growth factor expression in colon cancer cell lines of varying liver – colonizing capability. J.Cell Biochem 76: 332-340: 1999 87. Ben Ari G, Scott D, Zippel D, Sareli M , Koller M & Papa MZ. Continuos hyperthermic peritoneal perfusion (chpp) for malignant ascites & irresectable intraabdominal cancer. Japanese Jr. Cancer & Chemotherapy 27(5):436-439: 2000 . 88. Zvibel I. Brill S. , Papa MZ, Halpern Z . Hepatocyte-derived soluble factors regulate proliferation and autocrine growth factor expression in colon cancer cell lines of varying liver colonizing capability. Tumor Biology 21(4) 187- 196:2000. 89. Zvibel I, Brill S, Halpren Z, Moskovitz S, Yayon A and Papa MZ . soluble and matrix associated heparen sulfate proteoglycans increase expression of erb-B2 and Erb-B3 in colon cancer cell lines Int J. Cancer. 91:316- 321,2001 90. Zvibel I , Papa MZ., Halpren Z, and Brill S, Synergies of Heparin seconed messengers pathways involved in tissue specific gene expression in hepatocytes . Dig Dis Sciences 46:1039-1045: 2001. 91. Kouniavski G, Khaikin M, Zvibel I, Zippel D, Brill S, Halpren Z, Papa MZ. Stromal Extracelular matrix reduces chemotherapy- induced apoptosis in colon cancer cell lines. Clinical & Experimental liver Liver Metastases 19:55-60: 2002 92. Fishman F, Brill S, Papa MZ, & Zvibel I. Heparin derived disaccharides modulate proliferation and ERB2 signal transduction in colon cancer cell lines. Int J. Cancer, 99:179-184:2002. 93. Scott D. Papa MZ, Sareli M., Velano A., Ben Ari G. Koller M. Management of Hemorrhoidal disease in patients with chronic spinal cord injury . Techniques in Coloproctology 2002 Apr;6(1):19-22. 94. Shiri-Sverdlov R, Oefner P, Green L, Baruch RG, Wagner T.,Kruglikova A, Haitchick S, Hosfora RM, Papa MZ, Mulder I , Rizel S, Bar Sade RB, Dagan E,Abdeen Z., Goldman B, Friedman E. Mutational analysis of BRCA1 and BRCA2 in Ashkenazi and non Ashkenazi Jewish women with familial breast and ovarian cancer. Hum Mutat: 2000;16:491- 501. 95. Figer A, Karasik YP, Baruch RG, Chetrit A, Papa MZ, Sade RB, Riezel S, Friedman E. Insulin-like growth factor I polymorphism and breast cancer risk in Jewish women Isr Med Assoc J 2002 Oct;4(10):759-62. 96. 97. Figer A, Kaplan A, Frydman M, Lev D, Paswell J, Papa MZ, Goldman B, Friedman E. Germline mutations in the PTEN gene in Israeli patients with Bannayan-Riley-Ruvalcaba syndrome and women with familial breast cancer. : Clin Genet 2002 Oct;62(4):298-302 DiCastro M, Frydman M, Friedman I, Shiri-Sverdlov R, Papa MZ, Goldman B, Friedman E. Genetic counseling in hereditary breast/ovarian cancer in Israel:psychosocial impact and retention of genetic information Am J Med Genet 2002 Aug 1;111(2):147-51. 98. Zippel D. Sigelman – Danieli N, Ayalon S, Kaufman B., Pfeffer R, Papa MZ. Delayed Breast cellulites Following Breast Conserving Operation. European Jr. Surgical Oncol 29(4):327-330:2003. 99. Sadetzki S. Calderon M. Peretz C., NovikovI., Barchana M., Papa MZ. Second primary breast and thyroid cancers (Israel) Cancer Causes Control. 2003 May;14(4):367-75. 100. Zigelmann N, Tamir A, Zohar H, Papa MZ, Chertver LL, Galamidi Z, Stein M., Kuten A. Breast cancer in woman with recent exposure to fertility medication is associated with poor prognostic features. Ann Surg Onc; 10:1031-1038:2003 101. Gal I, Sadetzki S, Gershoni-Baruch R, Oberman B, Carp H, Papa MZ, Diestelman Menachem T, Barzilai Eizenberg S. Friedman E. : Offspring gender ratio and the rate of recurrent spontaneous miscarriages in Jewish women at high risk for breast/ovarian cancer. Am. Jr. of Human Genetics – 74(6):1270-1275:2004 102. Sarely Israelashvili M, Zipple D, Koller M, Valeanu A, Scott D, Ayalon S, Ben-Ari GY & Papa MZ. Use of trans portal balloon catheter occlusion of the portal Triad in prevention of bleeding during liver resection. Jr. of Surgical Oncology 89:39-42:2005. 103. Sadetzki S.Oberman B, Zipple D, Kaufman B, Rizel S, Novikov I & Papa MZ . Breast conservation after neo adjuvant chemotherapy. Ann of Surgical Oncol, 12(6): 480-7:2005. 104. Zippel D.& Papa MZ. The use of MRgFUS in breast cancer patients; a preliminary phase one stady and review. Japn Jr. Breast Cancer 12:32-38:2005 105. Ohayon T, Gershoni-Baruch R, Papa MZ, Distelman Menachem T, Eisenberg Barzilai S, Friedman E. The R72P P53 mutation is associated with familial breast cancer in Jewish women. British Journal of Cancer 92:1144-1148;2005. 106. Wolf I., Sadetzki S., , Gluck I., , Oberman B., Ben-David Merav, Papa MZ, Catane R., Kaufman B. Association between Diabetes Mellitus and adverse characteristics of breast cancer at presentation. Eur J Cancer 42:1077-1082, 2006. 107. Kopelman D., Inbar Yael , Hanannel A, , Freundlich D., Castel D., Perl A., Greenfeld A., Solomon T.l, Sareli M., Valeanu A.. Papa MZ : Magnetic resonance guided focused ultrasound surgery (MRgFUS) Ablation of liver tissue in procine model. Eur J of Rentgenology, Jan 2006 108. Baruchim Bar Sade R., Chetrit A., Figer A., Papa MZ., Flex D., Rizel S., Friedman E.: Hormon replacement therapy is more prevalent among Jewish BRCA1/2 mutation carriers. European J. of Cancer 42;650-655,2006. 109. Koren M., Kimmel G., Ben-Asher E., Gal I., Papa M.Z., Beckmann J.S., Lancet D., Shamir R., Friedman E. ATM haplotypes and breast cancer risk in Jewish high-risk women. British J of Cancer 1-7,2006. 110. Gal I., Kimmel G., Gershoni-Baruch R., Papa MZ., Dagan E., Shamir R., Friedman E.: A specific RAD51 haplotype increases breast cancer risk in Jewish non-Ashkenazi highrisk women . European J. of Cancer 42:1129-1134, 2006 111. Besser M., Treves AJ., HardanArnon I., Nagler A., Itzhaki O.,. Papa MZ, Catane R., Winkler A, Shalmon-Zifroni B, Schachter J., Adoptive Cell Therapy for Metastatic Melanoma Patients: Pre-clinical development at the Sheba Medical Center . The Isr. Medical Association. J. 8(3)164-168,2006 112. Kopelman D., Inbar Y., Hanannel A., Dank G., Freundlich D., Perel A., Castel D, Greenfeld A., Salomon T., Sareli M., Valeanu A.and Papa MZ. Magnetic resonance -guided focused ultrasound surgery (MRgFUS): Four Ablation treatments of a Single Canine Hepatocellular Adenoma. HPB Surgery, (Hepato-Billiary- Pancreatic Surgery) 2006 (in press) 113. Maor S., Mayer D., Yarden R., Lee A.V., Sarfstein R., Werner H., Papa MZ. Estrogen receptor regulates insulin-like growth factor- I receptor gene expression in breast tumor cells: involvement of transcription factor Sp1. J. of Endocrinology.191,605-612,2006. 114. Maor S.,Papa MZ.,Yarden R.,Friedman E.,Lerenthal Y., Lee SW., Mayer D.,Werner H. Insulin-like growth factor-I controls BRCA1 gene expression through activation of transcription factor Sp1. Hormone and Metabolic research. 1-7.2007 115 Atwal GS, Bond GL, Metsuyanim S, Papa M, Friedman E, Distelman-Menachem T, Ben Asher E, Lancet D, Ross DA, Sninsky J, White TJ, Levine AJ, Yarden R. Haplotype structure and selection of the MDM2 oncogene in humans. Proc Natl Acad Sci U S A. 2007 Mar 116 Maor S, Yosepovich A, Papa MZ, Yarden RI, Mayer D, Friedman E, Werner H. Elevated insulin-like growth factor-I receptor (IGF-IR) levels in primary breast tumors associated with BRCA1 mutations. Cancer Lett. 2007 Aug 31; B.1. Articles Accepted 1. Zipple D. Sadetzki S. Papa MZ. Timing of sentinel lymph node biopsy in patients receiving neoadjuvant chemotherapy for breast cancer. Submited Jr. Surg Oncol Feb 2007 B.1. Articles Submitted 1. Maor S, Papa MZ., Yarden R, Friedman E, Sam W. Lee, Mayer D. and Werner H. Coordinated regulation of the insulin-like growth factor system and BRCA1 in breast cancer cells. Submitted Molecular Genetics and Metabolism. 2. Perry S 1, Evron E., Stemmer Salomonn, Taub E. 2 & Papa MZ Psychological impact and preventive strategies following genetic testing for BRCA1/2 mutations. submitted to Jr. of Clinical Oncology . 3.. Zipple D., Papa MZ. Hepatic Venous anatomy- a study of 235 cadavric speciments . Submitted – Liver transplantation B.2. Case Reports 1. Schanzer H, Papa MZ¸ Miller C. Rupture of a thrombosed abdominal aortic aneurysm. Vasc Surg 1985;2:278-280. 2. Langer JL, Papa MZ, Hoffman M, Filler RM. Colonic perforation in cyclic neutropenia. J Pediat Surg 1990;25:346-348. 3. Yosepovich a. Perlmam M. Ayalon S. Papa MZ. Kopilovic J. Syringomatous adenoma of the nipple: a case report. Pathology-Research and Practice:201:405-407:2005. B.3. Review Articles Published 1. Bar-Meir S, Papa MZ. Antitrypsin deficiency associated with liver cirrhosis. Harefuah 1975;88:288-289. 2. Bar-Meir S, Papa MZ. Liver damage following salicylate intake. Harefuah 1975;88:247. 3. Papa MZ, Halpern Z, Bar-Meir S. Interferon in chronic active hepatitis. Harefuah 1981;101:27-28. 4. Reshef A, Papa MZ, Halpern Z, Lapidot M, Karasik A, Mozes M. Post mastectomy lymphedema. Harefuah 1983;104:41-43. _____________________________________________________________________ 5. Gayer G, Zissin R, Apter S, Papa MZ, Hertz M. Pictorial review: adult intussusception--a CT diagnosis. Br J Radiol. 2002 Feb;75(890):185-90. Review. 6. Papa MZ, Ayalon S. Muntz Y. Ben Ari G. The role of prophylactic mastectomy in genetically prone woman for breast cancer. Harfuah , Mar 15;136(6):474-6. 1999. 7. Ehernfeld M, Papa MZ, Adar R. Autoimmune mechanisms in Buerger’s disease. Critical Ischemia Journal Vol 11. 25-32: 2001. 8 Wolf I, Catane R, Symon Z, Papa MZ, Fieder HH, Update on the treatment of common gastrointestinal malignancies. Harfuah144(1):39-42:2005 9. Yarden R., Papa MZ.. BRCA1 at the Cross Road of Transcription, Chromatin Remodeling, DNA repair, Cell Cycle Control and Ubiquitylation: Approaches for Therapeutic Interventions. Molecular Cancer Therapuetics. Feb 2006 B.3. Review Articles Accepted 1. Kopelman D., Papa MZ.: Magnetic resonance guided focused ultrasound surgery (MRgFUS) for the noninvasive curative ablation of tumors and palliative treatment - a review. Annals of Surgical Oncology. C. CHAPTERS IN BOOKS Papa MZ, Adar R. Another look at Buerger’s disease. In: H. Boccalon, Ed. Vascular Medicine (Proc. of 16th World Congress of International Union of Angiology). Excerpta Medica 1993, pp. 113-116. _____________________________________________________________________ 2. Hughes KS, Papa MZ, Whitney T, McLellan R : prophylactic mastectomy and Inherited cancer predisposition, in: Shaw GL ed. Cancer genetics for the clinician. Plenum Publishing Corp. New York , 2000. 1. 3. Papa MZ. Sadetzki S, Regional Breast Cancer Treatment. Accepted Feb 2006