LEPESANT Julie M.J. 27 rue du Stade 66690 Saint André FRANCE Phone: + 33 (0)6 74 13 64 28 Email : julie.lepesant@free.fr : julie.lepesant@univ-perp.fr CURRICULUM VITAE FORMATION 2009-2012 PhD Student (present) Team Environmental and evolutive epigenetics of interactions UMR 5244 CNRS-UPVD (Perpignan) 2007-2009 Master Integrative Biology and Physiology (with honor) Speciality Comparative Biology and Physiology Pierre and Marie Curie University (Paris IV) 2006-2007 Third year of Organisms Biology Licence Speciality Aquatic Ecology Montpellier University (UM II) 2004-2006 First and second year of Biology Licence Joseph Fourier University (Grenoble I) 2004 Scientific High School Diploma, speciality Biology, european section (German) Highschool Champollion of Grenoble EXPERIENCES 2009-2012 PhD Student Team : Ecology and Evolution of Interactions Subject: The role of epigenetics in the generation of phenotypic variability in Schistosoma mansoni and its impact on infection success. Directors Mr Guillaume Mitta and Mr Christoph Grunau. Technics : Dissections, DNA and RNA extractions, QPCR, RT-PCR, Chromatin Immunoprecipitation, Massive sequencing 2009 (6 months) 2008 (3 months) Research training in Arago Laboratory in Banyuls sur Mer (Master 2) Team: Factors of the Mediums and Adaptive Mechanisms Subject: Study of the circadian rhythms and the gonadotropines in the seabass Dicentrarchus labrax. Directors Mr Jack Falcon Technics : Dissections of fishes brains, proteins extraction and quantification, enzymatic activity, QPCR, cloning, In Situ Hybridization Research training in Ecolag Laboratory in Montpellier II (Master 1) Team: Immunity Reactions, Aquaculture and Environment Subject: Contribution under investigation of the immune reaction in oyster Crassostrea gigas. Director Ms Viviane Boulo. Technics : RNA extractions, RT-PCR, QPCR, Agarose gels, Northern Blot 2007 (1 month) Voluntary Research training in Ecolag Laboratory in Montpellier II (Master 1) Team: Ecophysiologic Adaptation and Ontogenesis Subject: Study of the physiological adaptations of the seabass Dicentrarchus labrax to variations of salinity, Director Ms Patricia Cucchi-Mouillot. Technics: Fishery, immunohisto/cytochemestry, histology, Western Blot TEACHING 2009-2012 Practical classes of Animal Physiology (Licence), Animal cellular Physiology (Licence), Informatic certificate (Licence), Bibliography studies (Licence), Molecular Biology (Master) PUBLICATIONS 2011 Julie M.J. Lepesant, Céline Cosseau, Christoph Grunau. Towards an understanding of the epigenetics of schistosomes: A comparative epigenomic study. Memorias do Instituto Oswaldo Cruz (in press) {IF 2.097} Julie M.J. Lepesant, David Roquis, Rémi Emans, Céline Cosseau, Nathalie Arancibia, Guillaume Mitta, Christoph Grunau. De-novo assembly of massive sequencing reads into the repeat genome of Schistosoma mansoni and first-pass annotation. Internationnal Journal of Parasitology (submit) {IF 3,822} Julie M.J. Lepesant, Céline Cosseau, Jérome Boissier, Michael Freitag, Julien Portela, Déborah Climent, Cécile Perrin, Adhemar Zerlotini Neto, Christoph Grunau. The role of heterochromatization in sex chromosome emergence: lessons from the human parasite Schistosoma mansoni. Genome Biology (in correction). {IF 6.626}. COMMUNICATIONS ORAL PRESENTATIONS 2010 National Congress Lepesant J.M.J., Cosseau C., Perrin C., Mitta G. & Grunau C. (2010) A role for epigenetics in adaptative evolution. 13e congrès Young Researchers in Life Science (session : Hostpathogen interactions), Paris, June 7-9 2010 National Congress Lepesant J.M.J., Cosseau C., Perrin C., Mitta G. & Grunau C. (2010) Rôle de l’épigénétique dans l’évolution adaptatives. Congrès Ecologie 2010 (session : Intégration de l’interaction Génotype x Environnement dans l’étude des capacités d’adaptation), Montpellier, september 2-4 POSTERS 2011 International congress Herrero M.J., Isorna E., Besseau L., Fuentes M., Lepesant J.M.J., Sauzet S., Delgado M.J. & Falcon J. (2011) Daily variations of clock genes : testing endogenous rhythms and influence of exogenous melatonin in pituitary of sea bass (Dicentrarchus labrax). 8th congress of iberic association of compared endocrinology, Madrid, Spain, September 5-7 2011. 2011 International congress Lepesant J.M.J., Cosseau C., Boissier J., Rognon A. & Grunau C. (2011) Changes in the epigenome of a human parasite during expérimental adaptative évolution : antihelminth drug. ESF-EMBO Symposium : Epigenetics in Context: From Ecology to Evolution, Sant Feliu de Guixols, Spain, September 18-23 2011 2010 International Congress Lepesant J.M.J., Cosseau C., Portela J., Boissier J., Dejean B. & Grunau C. (2010) Chromatin status and transcription patterns of several new classes of female specific repeats of Schistosoma mansoni. ICOPA XII, Melbourne, Australia, August 15-20 2010 SCIENTIFIQUE VULGARISATION 2009 Joining author of the teaching case “Darwin, l’évolution c’est tout bête”. Case financed by CNRS, composed of 5 posters and 4 workshops (heredity, DNA, natural selection, tree of life), realized within the framework of a partnership between UMR CNRS 5096 and 5244 and association “Les Petits Débrouillars”. Inaugurated and animated at the time of the village of Sciences 2009 (November 23-23) at the convention center of Perpignan then diffused via the association in the school structures. INFORMATIC MAC et PC : Microsoft Word, Excel, Power Point, Keynote, Internet, logiciel libre R, GraphPad, logiciel LightCycler OTHERS French (maternal language) English (read, spoken and written)