Database: Ovid MEDLINE(R) <1966 to January Week 3 2004> Search Strategy: -------------------------------------------------------------------------------1 exp OSTEOCHONDRITIS/ (4914) 2 (knee or akle).af. (52356) 3 1 and 2 (726) 4 exp *OSTEOCHONDRITIS/ and 3 (506) 5 limit 4 to (human and english language) (284) 6 limit 5 to yr=1996-2004 (96) 7 osteochondritis.ti. and 6 (54) 8 6 (96) 9 limit 8 to ovid full text available (10) 10 limit 6 to review (15) 11 9 or 10 (23) 12 7 not 11 (43) 13 from 12 keep 1-2,7,9-10,12-22,24-25,27-28,30-31,33,35,37,39-40,43 (28) 14 from 10 keep 3,6,11-13 (5) 15 10 not 14 (10) 16 9 or 13 or 15 (46) 17 from 16 keep 1-46 (46) 18 from 17 keep 1-46 (46) *************************** <1> Unique Identifier 11573913 Authors Kocher MS. Micheli LJ. Yaniv M. Zurakowski D. Ames A. Adrignolo AA. Institution Department of Orthopaedic Surgery, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. Title Functional and radiographic outcome of juvenile osteochondritis dissecans of the knee treated with transarticular arthroscopic drilling. Source American Journal of Sports Medicine. 29(5):562-6, 2001 Sep-Oct. Abstract Management of juvenile osteochondritis dissecans is controversial. The purpose of this study was to evaluate the functional and radiographic outcomes of transarticular arthroscopic drilling for isolated stable, juvenile osteochondritis dissecans lesions of the medial femoral condyle with an intact articular surface after 6 months of nonoperative management had failed. We reviewed 30 affected knees in 23 skeletally immature patients (mean age, 12.3 years; range, 8.5 to 16.1) at an average follow-up of 3.9 years (range, 2.0 to 7.2). Functional outcome was determined using the Lysholm score and radiographic outcome was determined using lesion size, and the radiographic score of Rodegerdts and Gleissner. There was significant improvement in the mean Lysholm score (from 58 to 93). There was significant improvement in the mean lesion size on anteroposterior (4.5 +/- 5.8 mm decrease) and lateral (8.4 +/- 8.1 mm decrease) radiographs. There was also significant improvement in the mean radiographic score (from 3.0 to 1.9). Radiographic healing was achieved in all patients at an average of 4.4 months after drilling (range, 1 to 11 months). Linear regression analysis revealed that younger age was an independent, multivariate predictor of Lysholm score improvement. There were no apparent surgical complications. <2> Unique Identifier 9474395 Authors Paletta GA Jr. Bednarz PA. Stanitski CL. Sandman GA. Stanitski DF. Kottamasu S. Institution Department of Orthopaedic Surgery, Children's Hospital of Michigan, Detroit, USA. Title The prognostic value of quantitative bone scan in knee osteochondritis dissecans. A preliminary experience. Source American Journal of Sports Medicine. 26(1):7-14, 1998 Jan-Feb. Abstract We reviewed the records of 12 patients ages 9 to 16 years with knee osteochondritis dissecans. All patients had clinical histories and examinations, four radiographic views of the knee, and technetium-99m diphosphonate quantitative bone scans. Scan results (symmetric, increased, or decreased activity), clinical course, healing time, and final outcome were correlated to determine the prognostic value of the scan. We divided the patients into those with open physes (distal femoral and proximal tibial) and those with closed physes. Four of the six patients with open physes had increased activity on the bone scan. All four of these knees healed with nonsurgical treatment. The other two patients had decreased activity on bone scan, and both required surgical treatment after nonsurgical treatment failed. Of the six patients with closed physes, all had increased activity on the bone scan, but only two patients had healing of the osteochondral lesion without surgery. Quantitative bone scanning had a 100% predictive value for the prognosis in osteochondritis dissecans patients with open physes, but for those with closed physes the predictive value was less. Because the natural history in the adolescent group is less predictable, it is in this group that the quantitative scan would be most helpful. In this small group of patients, quantitative bone scanning had limited prognostic value. <3> Unique Identifier 10653545 Authors Peters TA. McLean ID. Institution Prahran Sports Medicine Centre, Victoria, Australia. Title Osteochondritis dissecans of the patellofemoral joint.[see comment]. Comments Comment in: Am J Sports Med. 2001 Jan-Feb;29(1):112-3; PMID: 11206248 Source American Journal of Sports Medicine. 28(1):63-7, 2000 Jan-Feb. Abstract Osteochondritis dissecans of the patellofemoral joint is an uncommon condition that may be the cause of anterior knee pain or crepitus. We present the clinical features of 37 patients with osteochondritis dissecans lesions of the patellofemoral joint (24 on the patella, 13 on the trochlear groove), including two patients with medial trochlear groove lesions, which have not, to our knowledge, been previously reported. The osteochondral lesions involved the convex articular surfaces. The median age of patients when first examined was 15 years, and 54% of patients had open epiphyses. These lesions were more common in male patients than in female patients (four-to-one ratio). Osteochondritis dissecans of the patellofemoral joint can be overlooked unless quality radiographs are viewed with care and, at arthroscopy, both the patella and trochlear groove are assessed. Treatment depends on the symptoms, site, and nature of the lesion and the patient's age. Nonoperative management includes patellar taping and vastus medialis obliquus muscle exercises. Operative intervention is indicated for patients with mechanical symptoms and includes arthroscopy, consisting of chondroplasty and removal of loose bodies, and lateral retinacular release. In this study treatment generally improved the symptoms, but patients with articular cartilage loss had persistent patellofemoral crepitus and discomfort. <4> Unique Identifier 12016089 Authors Yoshizumi Y. Sugita T. Kawamata T. Ohnuma M. Maeda S. Institution Department of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan. Title Cylindrical osteochondral graft for osteochondritis dissecans of the knee: a report of three cases. Source American Journal of Sports Medicine. 30(3):441-5, 2002 May-Jun. <5> Unique Identifier 11206248 Authors Smith JS. Title Osteochondritis dissecans of the patellofemoral joint.[comment]. Comments Comment on: Am J Sports Med. 2000 Jan-Feb;28(1):63-7; PMID: 10653545 Source American Journal of Sports Medicine. 29(1):112-3, 2001 Jan-Feb. <6> Unique Identifier 11599758 Authors Blankstein A. Cohen I. Heim M. Diamant L. Salai M. Chechick A. Ganel A. Institution Department of Orthopaedic Surgery, Sheba Medical Center, Tel-Hashomer, Israel. Title Ultrasonography as a diagnostic modality in Osgood-Schlatter disease. A clinical study and review of the literature. [Review] [14 refs] Source Archives of Orthopaedic & Trauma Surgery. 121(9):536-9, 2001 Oct. Abstract Sonographic examination of the knee has been proposed by several authors in the past as a simple and reliable method to diagnose Osgood-Schlatter disease (OSD). Ultrasound was used to compare the knees of 25 boys and 10 girls with typical OSD with 35 symptom-free knees of an aged-matched group of children. Based on recorded data, patients were categorized (one affected knee in each individual) according to the classification system proposed by De Flaviis et al. in 1989. The results included the following pathological findings: pretibial swelling, fragmentation of the ossification center, insertional thickening of the patellar tendon, and excessive fluid collection in the infrapatellar bursa. Of our patients, 26% fell into the type 1 category, 43% were type 2, 20% type 3, and 11% type 4. This distribution of cases was found to be statistically similar to the initial findings reported by De Flaviis and colleagues. This study therefore supports the validity and reproducibility of their classification method for the ultrasonographic evaluation of children with OSD. This is only the first step, and further assessment of this classification is still required to elucidate its clinical as well as its prognostic value. [References: 14] <7> Unique Identifier 11536094 Authors Aglietti P. Ciardullo A. Giron F. Ponteggia F. Institution First Orthopaedic Clinic, University of Florence, Florence, Italy. Title Results of arthroscopic excision of the fragment in the treatment of osteochondritis dissecans of the knee. Source Arthroscopy. 17(7):741-6, 2001 Sep. Abstract PURPOSE: To evaluate clinical and radiological results of arthroscopic excision of the fragment and debridement of the crater in the treatment of osteochondritis dissecans of the knee (OCD). Type of Study: Case series. METHODS: We investigated 20 patients with partial or complete detachment of the OCD fragment. The average age at surgery was 21 years (range, 12 to 32 years). All the patients were treated by the same surgeon. They were evaluated at an average follow-up of 9 years (range, 6 to 17 years). RESULTS: The combined subjective and objective evaluation showed excellent and good results for 85% of the patients. Radiographic studies showed 2 grades of worsening (from no degenerative signs preoperatively to narrowing of the joint line up to 50% at follow-up) in 1 patient (5%). One grade of worsening (Fairbank's changes without joint space narrowing) was found in 45% of weight-bearing anteroposterior radiographic views and in 35% of weight-bearing bent knee posteroanterior views. Statistical correlations were significant between radiographic degenerative changes and the size of the osteochondral lesion at surgery, with larger lesions resulting in greater degenerative changes. CONCLUSIONS: The arthroscopic removal of an osteochondral fragment and debridement of the crater is a viable option in the treatment of grade III and IV OCD lesions. Results are better in lesions less than 2 cm(2). <8> Unique Identifier 11447548 Authors Mizuta H. Nakamura E. Otsuka Y. Kudo S. Takagi K. Institution Department of Orthopaedic Surgery, Kumamoto University School of Medicine, Kumamoto, Japan. mizuta@kaiju.medic.kumamoto-u.ac.jp Title Osteochondritis dissecans of the lateral femoral condyle following total resection of the discoid lateral meniscus. Source Arthroscopy. 17(6):608-12, 2001 Jul. Abstract PURPOSE: The purpose of this study was to describe the clinical presentation of 6 athletically active children with symptomatic osteochondritis dissecans (OCD) of the lateral femoral condyle following total resection for a torn discoid lateral meniscus and to discuss its cause. TYPE OF STUDY: Case series. METHODS: Six patients in whom OCD affecting the lateral femoral condyle developed after total resection of the discoid lateral meniscus participated in a detailed clinical, radiologic, and arthroscopic review. The average age at the time of meniscectomy was 9 years (range, 6 to 12 years). At a mean of 50 months (range, 36 to 65 months) after surgery they developed recurrent pain in the treated knee; all had radiologic abnormalities at the lateral femoral condyle consistent with OCD. Before the recurrence of pain, all patients had been continuously engaged in sports activity. Radiologic and arthroscopic findings of the OCD lesions were assessed. Clinical outcomes of surgical treatment for OCD were also documented. RESULTS: The radiographic evaluation showed all lesions to be in the central portion of the lateral femoral condyle on the anteroposterior views and posteriorly next to a line extending distally from the posterior femoral cortex on the lateral views. Arthroscopic evaluation revealed softening in 2 knees, a separated fragment in 2 knees, and a completely loose fragment in 2 knees. All lesions were treated surgically, including 2 drillings of the lesion, 2 fixations of separated fragment, and 2 excisions of loose bodies with drilling. At an average follow-up period of 51 months (range, 22 to 77 months), all patients but 1 were asymptomatic. CONCLUSIONS: Repeated impaction in sports activities on the immature osteochondral structures under altered mechanical force transmission after total resection of the discoid meniscus might be a predisposing factor in the development of OCD in the lateral femoral condyle. <9> Unique Identifier 11337726 Authors Friederichs MG. Greis PE. Burks RT. Institution Department of Orthopedics, University of Utah Medical Center, Salt Lake City, Utah, U.S.A. Title Pitfalls associated with fixation of osteochondritis dissecans fragments using bioabsorbable screws. Source Arthroscopy. 17(5):542-5, 2001 May. Abstract The purpose of this study was to evaluate 2 cases in which bioabsorbable screw fixation for an osteochondritis dissecans lesion of the femoral condyle resulted in complications necessitating the need for secondary surgery. We reviewed the case history of these patients and described the circumstances under which the bioabsorbable screws were used, the events leading to the need for secondary surgery, and the ultimate outcome. In the 2 cases presented, these implants were found to retain their mechanical stiffness for many months. This resulted in articular damage in 1 case after the treated lesion failed to heal. In the second case, screw breakage 8 months after implantation resulted in it becoming a loose body, which required removal during a second arthroscopic procedure. We conclude that these implants retain their mechanical properties for many months and cannot be relied on to degrade quickly. If a treated lesion fails to heal, these implants can cause mechanical problems due to their retained structural properties. <10> Unique Identifier 11027774 Authors Kim SJ. Shin SJ. Institution Department of Orthopaedic Surgery, Arthroscopic Surgery Unit, Yonsei University College of Medicine, Seoul, Korea. jinos@yumc.yonsei.ac.kr Title Loose bodies after arthroscopic osteochondral autograft in osteochondritis dissecans of the knee. Source Arthroscopy. 16(7):E16, 2000 Oct. Abstract We report a case of loose bodies from the donor site as a complication after the osteochondral autograft for the treatment of osteochondritis dissecans. Eight months after surgery, 3 osteochondral loose fragments, having dislodged from the donor sites of the osteochondral autograft, were found in the posteromedial portion, posterolateral portion, and anterior compartment of the knee, respectively. A large osteochondral defect can be treated successfully with arthroscopic autogenous bone graft. When filling the donor site with the recipient bone core, only the cancellous portion should be inserted into the donor socket. <11> Unique Identifier 10231112 Authors Berlet GC. Mascia A. Miniaci A. Institution Department of Surgery, University of Toronto, and The Toronto Western Hospital, Ontario, Canada. Title Treatment of unstable osteochondritis dissecans lesions of the knee using autogenous osteochondral grafts (mosaicplasty). Source Arthroscopy. 15(3):312-6, 1999 Apr. Abstract Symptomatic osteochondritis dissecans lesions with minimal fragmentation that may be replaced within their crater have classically been treated by reattachment. The choice for internal fixation is varied. This article reports on the treatment of unstable osteochondritis dissecans lesions using autogenous osteochondral plugs as a means of biological internal fixation. The appearance on magnetic resonance imaging of osteochondral plugs at 6 and 9 months after transplantation is also presented. <12> Unique Identifier 10024029 Authors Mitsuoka T. Shino K. Hamada M. Horibe S. Institution Department of Orthopaedic Sports Medicine, Osaka Rosai Hospital, Japan. Title Osteochondritis dissecans of the lateral femoral condyle of the knee joint. Source Arthroscopy. 15(1):20-6, 1999 Jan-Feb. Abstract Differences in the features of osteochondritis dissecans (OCD) affecting the lateral and medial femoral condyles were investigated in 13 patients (14 knees) treated from 1991 to 1994. OCD affected the lateral femoral condyle in 6 knees (lateral group) and the medial condyle in 8 knees (medial group). The lateral group was younger (mean age, 14 v. 20 years). The radiological stage (Bruckl) of the lateral group was stage 2 in 3 knees and stage 3 in 3. The lateral menisci were all discoid and the condylar articular surface of the lesions was normal in two knees, softened in 3 and detached in 1. The medial group comprised 1 knee in stage 2, 1 in stage 3, 1 in stage 4, and 5 in stage 5. The OCD lesion showed softening in 2 knees and detachment in 6. Repetitive abnormal stress on weaker osteochondral structures in the growing period produced by a discoid meniscus during growth may cause OCD of the lateral femoral condyle. <13> Unique Identifier 9754485 Authors Mitsuoka T. Horibe S. Hamada M. Institution Department of Orthopaedic Sports Medicine, Osaka Rosai Hospital, Japan. Title Osteochondritis dissecans of the medial femoral condyle associated with congenital hypoplasia of the lateral meniscus and anterior cruciate ligament. Source Arthroscopy. 14(6):630-3, 1998 Sep. Abstract We report a patient with osteochondritis dissecans of the medial femoral condyle associated with congenital hypoplasia of the lateral meniscus and anterior cruciate ligament. This is the first report of such a case. <14> Unique Identifier 9195028 Authors Anderson AF. Richards DB. Pagnani MJ. Hovis WD. Institution Lipscomb Clinic, Nashville, Tennessee 37203, USA. Title Antegrade drilling for osteochondritis dissecans of the knee. Source Arthroscopy. 13(3):319-24, 1997 Jun. Abstract Twenty-four knees with osteochondritis dissecans of the femoral condyles failed a conservative program and were treated with antegrade drilling. To our knowledge, this represents the largest reported series using this technique. The average age at the time of surgery was 13 years 6 months. Seventeen patients had open physes, and four were skeletally mature. Nineteen lesions involved the medial femoral condyle, and five involved the lateral femoral condyle. The average follow-up was 5 years. Postoperative evaluation included rating by the International Knee Documentation Committee (IKDC) form and the Hughston Rating Scale for osteochondritis dissecans. Twenty of the 24 lesions healed after antegrade drilling, and the average time of healing was 4 months. According to the criteria on the IKDC grading form, 14 were normal, 6 nearly normal, three abnormal, and one severely abnormal. The results of the Hughston Rating Scale were similar: 15 were excellent, seven good, one fair, and one poor. Only two of the four skeletally mature patients healed after antegrade drilling. Antegrade drilling is an effective method of treatment for osteochondritis dissecans of the knee that occurs in adolescents with open physes. This operation is not as likely to result in a successful outcome in patients with closed physes; consequently, other methods should be considered in skeletally mature patients. <15> Unique Identifier 8864013 Authors Victoroff BN. Marcus RE. Deutsch A. Institution Department of Orthopaedic Surgery, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA. Title Arthroscopic bone peg fixation in the treatment of osteochondritis dissecans in the knee. Source Arthroscopy. 12(4):506-9, 1996 Aug. Abstract An arthroscopic method for the treatment of osteochondritis dissecans lesions in the knee is described. The technique involves using autogenous bone pegs for arthroscopic transfixion of femoral osteochondritis dissecans (OCD) lesions. The method represents a simple biological alternative for arthroscopic fixation of OCD lesions. <16> Unique Identifier 11172259 Authors Scioscia TN. Giffin JR. Allen CR. Harner CD. Institution Department of Orthopaedics, the University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A. Title Potential complication of bioabsorbable screw fixation for osteochondritis dissecans of the knee. Source Arthroscopy. 17(2):E7, 2001 Feb. Abstract The 3 cases presented describe loosening or failure of bioabsorbable screws in the treatment of osteochondritis dissecans (OCD). In case 1, a 17-year-old boy with OCD of the medial femoral condyle was treated with bioabsorbable screw fixation. Six months after surgery, the patient had an acute episode of pain with effusion. Arthroscopic examination revealed 2 of the 4 screws backed out, causing cartilage damage to the corresponding tibial plateau. The shafts of the remaining 2 screws had completely absorbed, leaving the unabsorbed screw heads as intra-articular loose bodies in the knee. Unpredictable and inconsistent degradation of the screws is believed to be the mechanism for screw back-out and cartilage damage. <17> Unique Identifier 11774158 Authors Nakagawa Y. Matsusue Y. Nakamura T. Institution Department of Orthopaedic Surgery, Faculty of Medicine, Kyoto University, Kyoto, Japan. ynaka@kuhp.kyoto-u.ac.jp Title A novel surgical procedure for osteochondritis dissecans of the lateral femoral condyle: Exchanging osteochondral plugs taken from donor and recipient sites. Source Arthroscopy. 18(1):E5, 2002 Jan. Abstract We treated a 16-year-old boy who had a large symptomatic osteochondritis dissecans (OCD) lesion of the lateral femoral condyle by exchanging osteochondral plugs taken from the donor site with plugs taken from the recipient site. At final inspection 36 months after surgery, he had full range of motion and no symptoms in his knees. Our methods can be used to treat grade 2 or 3 OCD lesions, as classified by Clanton and DeLee. <18> Unique Identifier 12724672 Authors Nakagawa Y. Matsusue Y. Suzuki T. Nakamura T. Institution Department of Orthopaedic Surgery, Faculty of Medicine, Kyoto University, Kyoto, Japan. ynaka@kuhp.kyoto-u.ac.jp Title Arthroscopic osteochondral grafting in fissuring osteochondritis dissecans of the knee. Source Arthroscopy. 19(5):E48, 2003 May-Jun. Abstract We encountered a rare case of osteochondritis dissecans in a 13-year-old girl, in which magnetic resonance imaging appeared to show migration of the joint cartilage into the bone marrow of the femoral condyle, with fissuring visible on the joint cartilage. Arthroscopy showed fissuring, 5 x 20 mm, in the right lateral femoral condyle, and the articular cartilage in the center of the lesion had fibrillation and was depressed about 5 mm. We performed arthroscopic osteochondral grafting to the lesion. The microscopic findings showed that the lesion had fibrillated bone marrow and that the cartilage existed only in the superficial layer of the lesion. Twenty-seven months after surgery, the patient was able to participate in sports and had no knee pain. <19> Unique Identifier 11951196 Authors Jurgensen I. Bachmann G. Schleicher I. Haas H. Institution Orthopaedic Department, Justus-Liebig-University of Giessen, Germany. Ingke.Juergensen@ortho.med.uni-giessen.de Title Arthroscopic versus conservative treatment of osteochondritis dissecans of the knee: value of magnetic resonance imaging in therapy planning and follow-up. Source Arthroscopy. 18(4):378-86, 2002 Apr. Abstract PURPOSE: Magnetic resonance imaging (MRI) was used to control the short-term outcome of osteochondritis dissecans (OCD) of the femoral condyle depending on conservative or surgical treatment at the beginning of therapy. TYPE OF STUDY: Case series. METHODS: Treatment planning for OCD depended on the stage on MRI when analyzing the appearance of the interface between parent bone and fragment on T1- and T2-weighted images. Twenty-seven patients received conservative treatment and 46 patients underwent arthroscopic surgery. After 20 to 24 months, patients were re-evaluated by MRI to assess the condition of bony fragment, parent bone, and interface so as to determine partial or complete remission, no change, or progression of OCD. RESULTS: After conservative treatment, MRI showed partial or complete remission in 30% of patients and no change in 63%. Arthroscopic treatment led to remission in 37% and to no change in 57%. Progressive disintegration of OCD was found on MRI in 7% of conservatively treated patients and in 7% of the surgery patients. In 33.3% of the patients initially treated conservatively, it was decided to treat them arthroscopically because of ongoing, unacceptable clinical symptoms. CONCLUSIONS: The rates of remission and progression were not significantly different between the groups. The patients' age was significantly correlated to the rate of consolidation. OCD in juveniles under 16 years of age followed a milder course than in adults. <20> Unique Identifier 12368780 Authors Navarro R. Cohen M. Filho MC. da Silva RT. Institution Knee Division, Department of Orthopaedic Surgery, Federal University of Sao Paulo, Sao Paulo, Brazil. Title The arthroscopic treatment of osteochondritis dissecans of the knee with autologous bone sticks. Source Arthroscopy. 18(8):840-4, 2002 Oct. Abstract PURPOSE: To present a new surgical technique for the fixation of partial dislocated osteochondral fragments in athletes with osteochondritis dissecans (OCD) of the knee. TYPE OF STUDY: Retrospective case series. METHODS: Autologous bone sticks were taken from the ipsilateral tibial metaphysis and used in the arthroscopic fixation of unilateral osteochondritis dissecans of the knee in 11 patients (5 female and 6 male). Patient age ranged from 11 to 20 years (mean, 16 years). Fixation of the partially dislocated fragments of the OCD of the knee was performed following a modified arthroscopic procedure and autologous bone graft. RESULTS: Follow-up ranged from 15 to 108 months (mean, 48 months). Based on modified criteria of Hughston et al., results were satisfactory in 90.9% and unsatisfactory in 9.1% of the cases. CONCLUSIONS: Arthroscopic fixation of OCD of the knee with autologous bone sticks is technically simple and nonaggressive and provides satisfactory results in most cases. <21> Unique Identifier 10845971 Authors Bentley G. Minas T. Institution Institute of Orthopaedics, Royal National Orthopaedic Hospital, Stanmore HA74LP. gbentley@ucl.ac.uk Title Treating joint damage in young people. [Review] [20 refs] Source BMJ. 320(7249):1585-8, 2000 Jun 10. <22> Unique Identifier 14577709 Authors Browne RF. Murphy SM. Torreggiani WC. Munk PL. Marchinkow LO. Institution Department of Radiology, The Adelaide and Meath Hospital, Tallaght, Dublin 24, Ireland. Title Radiology for the surgeon: musculoskeletal case 30. Osteochondritis dissecans of the medial femoral condyle. Source Canadian Journal of Surgery. 46(5):361-3, 2003 Oct. <23> Unique Identifier 9269169 Authors Slawski DP. Institution Department of Orthopedic Surgery, USAF Medical Center, Scott Air Force Base, IL, USA. Title High tibial osteotomy in the treatment of adult osteochondritis dissecans. Source Clinical Orthopaedics & Related Research. (341):155-61, 1997 Aug. Abstract This study reports one surgeon's experience using valgus high tibial osteotomy in the treatment of osteochondritis dissecans of the medial femoral condyle in adult patients. Seven knees in six patients with osteochondritis dissecans were reviewed as the basis of the study. Five patients (five knees) were men, and one patient (two knees) was a woman. The average age at surgery was 32 years. Patients reported medial knee pain, recurrent effusions, and disability. An average of three procedures per knee had been performed previously. Four knees had achieved union of the osteochondral fragments but with overlying articular cartilage degeneration observed at arthroscopy. Three knees had failed attempts at fixation with eventual excision of the fragmented osteochondral lesions. None of the knees showed diffuse medial compartment gonarthrosis by radiographic or arthroscopic examinations. Involved knees had relative varus malalignment with an average femoral and tibial angle of 0 degree compared with the uninvolved knees average of 5 degrees valgus. Preoperative technetium scintigraphy showed isolated uptake in the medial femoral condyle of all involved knees. Preoperative Lysholm scores averaged 39 points. Patients were observed for an average of 30 months after surgery. The average Lysholm score at latest followup was 89 points. Femoral and tibial angles averaged 9 degrees valgus. On subjective questioning, all patients reported marked improvement, satisfaction with the surgery, and said they had no need for additional operative intervention. <24> Unique Identifier 9917687 Authors Dervin GF. Keene GC. Chissell HR. Institution Department of Surgery, Ottawa General Hospital, Ottawa, Canada. Title Biodegradable rods in adult osteochondritis dissecans of the knee. Source Clinical Orthopaedics & Related Research. (356):213-21, 1998 Nov. Abstract Symptomatic osteochondritis dissecans of the knee in skeletally mature patients does not follow a predictable natural history and there has been a trend toward internal fixation of the unstable fragment(s) where possible. Biodegradable implants are enticing for intraarticular use: implant removal is unnecessary and its degradation potentially allows a gradual shift of loading stress to the fracture site. Nine patients with a mean age of 18.6 years (range, 14-23 years) deemed skeletally mature by plain film radiography underwent internal fixation of fragments by 2-mm self reinforced polylactic rods. Six procedures were completed arthroscopically and three required arthrotomy. All fragments were of the medial femoral condyle. The procedure was tolerated well although three patients had early postoperative serosanguinous effusions develop that did not recur after one aspiration. At a mean followup of 33 months (range, 24-54 months), eight fragments radiographically were united whereas one remained ununited at 26 months, accounting for the one poor result in this series. Seven patients had good to excellent results according to Hughston's criteria and were satisfied with the procedure. One of these seven patients had a spontaneous effusion develop at 5 months that did not recur after aspiration and intraarticular steroid injection. Severe, unremitting synovitis did not occur in any patient. Internal fixation of osteochondritis dissecans of the knee with biodegradable polylactic rods provided satisfactory control of symptoms in the short term and resulted in radiographically stable lesions in eight of nine patients. These rods may be suited best for fragmented lesions with intact articular cartilage as an adjunct to drilling. <25> Unique Identifier 10943196 Authors Outerbridge HK. Outerbridge RE. Smith DE. Institution Division of Orthopaedic Surgery, University of Queensland, Princess Alexandra Hospital, Woolloongabba, Australia. Title Osteochondral defects in the knee. A treatment using lateral patella autografts. Source Clinical Orthopaedics & Related Research. (377):145-51, 2000 Aug. Abstract Sixteen patients (13 males and three females; average age, 27 years) with large symptomatic osteochondral defects of the femoral condyle were treated with an osteochondral autograft taken from the ipsilateral lateral patellar facet. Two patients had bilateral procedures for a total of 18 knees. These patients were followed up prospectively with an average followup of 7.6 years (range, 214.6 years). Cincinnati knee scores showed significant changes, from an average preoperative score of 37 to an average final followup score of 85. In all of the patients, knee function was improved, and they were able to return to their normal lifestyle with minimal or no restriction. Eighty-one percent of patients have returned to a high level of functioning. <26> Unique Identifier 8542693 Authors Matsusue Y. Nakamura T. Suzuki S. Iwasaki R. Institution Department of Orthopaedic Surgery, Faculty of Medicine, Kyoto University, Japan. Title Biodegradable pin fixation of osteochondral fragments of the knee. Source Clinical Orthopaedics & Related Research. (322):166-73, 1996 Jan. Abstract The authors present 3 cases of osteochondritis and 2 cases of osteochondral fracture of the knee. These cases were treated with a bioabsorbable ultra high strength poly (L-lactide) pin, which has the highest mechanical strength value of any nonfiber reinforced poly (L-lactide) reported previously. Three of the patients were male, and 2 were females; their ages ranged from 12 to 21 years. The followup period ranged from 2 years to 7 years 9 months (mean, 4.1 years). Two to 4 poly (L-lactide) pins with a diameter of 2 mm were used to fix the osteochondral fragments or the transplanted autogenous osteochondral grafts. In all cases, satisfactory bone union was obtained, and no inflammatory reaction was observed during the entire followup periods. The ranges of motion were normal, and there was no pain in any of the cases. It is concluded that the poly (L-lactide) pin is safe and useful in the repair of osteochondral fractures of the knee and in fixing grafted osteochondral fragments. <27> Unique Identifier 11398358 Authors Birk GT. DeLee JC. Institution Department of Orthopaedics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA. Title Osteochondral injuries. Clinical findings. [Review] [45 refs] Source Clinics in Sports Medicine. 20(2):279-86, 2001 Apr. Abstract Osteochondral injuries are common, mainly affecting a young, active population. Failure to recognize these injuries can lead to long-term disability. A heightened awareness and understanding of the common mechanisms of injury will lead to early diagnosis and rapid recovery. This, along with improved treatment modalities, will keep any long-term disability to a minimum. [References: 45] <28> Unique Identifier 9012566 Authors Obedian RS. Grelsamer RP. Institution Hospital for Joint Diseases, New York, New York, USA. Title Osteochondritis dissecans of the distal femur and patella. [Review] [69 refs] Source Clinics in Sports Medicine. 16(1):157-74, 1997 Jan. Abstract Osteochondritis dissecans (OCD) is a pathologic process characterized by a partial or total separation of a fragment of bone with overlying articular cartilage. OCD may affect any joint, but the knee joint is affected most commonly. This article reviews several potential causes of OCD and classification systems for OCD. Diagnosis and treatment strategies are discussed. [References: 69] <29> Unique Identifier 11398359 Authors Cahill BR. Ahten SM. Institution University of Illinois College of Medicine, Peoria, Illinois, USA. brcahill@mtco.com Title The three critical components in the conservative treatment of juvenile osteochondritis dissecans (JOCD). Physician, parent, and child. [Review] [12 refs] Source Clinics in Sports Medicine. 20(2):287-98, vi, 2001 Apr. Abstract There has been explosive growth of intensive, year-round sports for children of both sexes, with a resulting high degree of family involvement and commitment. Consequently, a diagnosis of juvenile osteochondritis dissecans (JOCD) impacts parent and child on many different levels. Compliance is the key element when a conservative treatment plan for JOCD is appropriate. An informed physician understands the dynamics between the "compliance triad" of physician, parent, and child, and recognizes that compliance is a process with foreseeable stages and characteristic behaviors. [References: 12] <30> Unique Identifier 12544270 Authors Robertson W. Kelly BT. Green DW. Institution Hosptial for Special Surgery, New York, New York 10021, USA. greendw@hss.edu Title Osteochondritis dissecans of the knee in children. [Review] [54 refs] Source Current Opinion in Pediatrics. 15(1):38-44, 2003 Feb. Abstract Osteochondritis dissecans is a term used to describe the separation of an articular cartilage subchondral bone segment from the remaining articular surface. Juvenile osteochondritis dissecans describes an osteochondritis dissecans lesion found in skeletally immature children with a maximum incidence occurring between the ages of 10 and 20. It is found more frequently in children who are active athletically and involved in organized sports and is twice as common in males as in females. Although the etiology of these lesions is unclear, it is believed that repetitive microtrauma may interrupt the already tenuous epiphyseal blood supply in the growing child and contribute to the development of osteochondritis dissecans lesions. Treatment is dependent upon age at presentation, fragment size, fragment location, and fragment stability. Stable lesions in skeletally immature patients are generally amenable to conservative management. Failed conservative management or unstable lesions will more likely require surgical intervention. Lesions in skeletally mature patients have a more unpredictable course and may require surgery. This review article discusses the anatomy, etiology, evaluation, classification, treatment, and expected outcome of osteochondritis dissecans lesions. [References: 54] <31> Unique Identifier 12760576 Authors Santrock RD. Buchanan MM. Lee TH. Berlet GC. Institution The Ohio State University College of Medicine, and Public Health, 6200 Cleveland Avenue, Columbus, OH 43231, USA. Title Osteochondral lesions of the talus. [Review] [57 refs] Source Foot & Ankle Clinics. 8(1):73-90, viii, 2003 Mar. Abstract Osteochondral lesions of the talus (OLT) are rare joint disorders. The talus is the third most common location of this disorder, following the knee and elbow joints. OLT represents 4% of all osteochondral lesions in the body. This article discusses the surgical treatment and postoperative rehabilitation of osteochondral lesions of the talus. [References: 57] <32> Unique Identifier 9347299 Authors Hangody L. Kish G. Karpati Z. Szerb I. Eberhardt R. Institution Budapest Uzsoki Hospital, Department of Orthopaedic & Trauma, Hungary. Title Treatment of osteochondritis dissecans of the talus: use of the mosaicplasty technique--a preliminary report. Source Foot & Ankle International. 18(10):628-34, 1997 Oct. Abstract A one-stage autogenous osteochondral grafting technique for the treatment of talar dome osteochondritis dissecans is described. Eleven patients with osteochondritis dissecans lesions, 10 mm or greater in diameter, were operated on using the mosaicplasty autogenous osteochondral transplantation technique. Osteochondral cylindrical grafts from the ipsilateral knee were delivered into the talar defect using specially designed tube chisels. These procedures were done by arthrotomy. With follow-up of 12 to 28 months (mean, 16 months), the patients returned to full activities and the results, using the Hannover scoring system, have been excellent. <33> Unique Identifier 11503979 Authors Hangody L. Kish G. Modis L. Szerb I. Gaspar L. Dioszegi Z. Kendik Z. Institution Uzsoki Hospital, Orthopaedic & Trauma Department, Budapest, Hungary. hangody@axelero.hu Title Mosaicplasty for the treatment of osteochondritis dissecans of the talus: two to seven year results in 36 patients. Source Foot & Ankle International. 22(7):552-8, 2001 Jul. Abstract An osteochondral defect (OCD) is known as a symptomatic lesion causing pain, recurrent synovitis, and altered joint mechanics most commonly in a weightbearing joint. Loose bodies may develop, which may then cause joint destruction and/or locking. The damage to the articular surface is most likely a precursor of ankle osteoarthritis. With the recent advances in diagnostic imaging, such as MRI, as well as the development of ankle arthroscopy, the identification and classification of these lesions has become much more precise. This allows more accurate staging and improves treatment recommendations. The assessment of a particular treatment is also improved. A variety of treatment alternatives are now available. These include arthroscopic procedures including debridement, retrograde drilling, and bone grafting. Compared to open treatment, arthroscopic procedures may be particularly advantageous in the treatment of small defects and stable OCD lesions. Until recently, however, favorable results have been less predictable for large or unstable osteochondral defects. We treat these more difficult lesions with a mosaic autogenous osteochondral transplantation. In our hands, this appears to provide an optimal treatment result. The present report evaluates the clinical outcome of 36 patients followed for two to seven years after a mosaicplasty autogenous osteochondral transplantation from a non or less weight bearing portion of the knee to the ipsilateral talus. Ankle function was measured by the Hannover scoring system and showed good to excellent results in 34 cases (94%) with no long term donor site morbidity. The encouraging clinical results are supplemented with radiographs and histology, which support the premise of lasting relief of symptoms and prevention of ankle arthrosis. <34> Unique Identifier 11922369 Authors O'Connor MA. Palaniappan M. Khan N. Bruce CE. Institution Royal Liverpool Children's Hospital, Alder Hey, England, UK. Title Osteochondritis dissecans of the knee in children. A comparison of MRI and arthroscopic findings. Source Journal of Bone & Joint Surgery - British Volume. 84(2):258-62, 2002 Mar. Abstract The treatment of osteochondritis dissecans (OCD) in children and adolescents is determined by the stability of the lesion and the state of the overlying cartilage. MRI has been advocated as an accurate way of assessing and staging such lesions. Our aim was to determine if MRI scans accurately predicted the subsequent arthroscopic findings in adolescents with OCD of the knee. Some authors have suggested that a high signal line behind a fragment on the T2weighted image indicates the presence of synovial fluid and is a sign of an unstable lesion. More recent reports have suggested that this high signal line is due to the presence of vascular granulation tissue and may represent a healing reaction. We were able to improve the accuracy of MRI for staging the OCD lesion from 45% to 85% by interpreting the high signal T2 line as a predictor of instability only when it was accompanied by a breach in the cartilage on the T1-weighted image. We conclude that MRI can be used to stage OCD lesions accurately and that a high signal line behind the OCD fragment does not always indicate instability. We recommend the use of an MRI classification system which correlates with the arthroscopic findings. <35> Unique Identifier 11922365 Authors Gautier E. Kolker D. Jakob RP. Institution Department of Orthopaedic Surgery, Kantonsspital, Fribourg, Switzerland. Title Treatment of cartilage defects of the talus by autologous osteochondral grafts. Source Journal of Bone & Joint Surgery - British Volume. 84(2):237-44, 2002 Mar. Abstract We reviewed retrospectively 11 patients who had been treated surgically by open autologous osteochondral grafting for symptomatic chondral or osteochondral defects of the dome of the talus between 1996 and 1999. The mean ages of the eight men and three women were 34.2 and 25.9 years, respectively, with a mean time to follow-up of 24 months. The results of functional outcome were prospectively obtained using the MODEMS AAOS foot and ankle follow-up questionnaire, the AOFAS ankle-hindfoot scale and the Hannover scores for the ankle. The grafts were harvested from the ipsilateral knee. Good to excellent results were obtained for the ankle without adverse effects on the knee. We believe that autologous osteochondral grafting should be considered for the patient with a symptomatic osteochondral defect of the talus. <36> Unique Identifier 12721341 Authors Peterson L. Minas T. Institution Brittberg M. Lindahl A. Institution for Orthopaedics, Gothenburg University, Sahlgrenska University Hospital, Sweden. Title Treatment of osteochondritis dissecans of the knee with autologous chondrocyte transplantation: results at two to ten years. Source Journal of Bone & Joint Surgery - American Volume. 85-A Suppl 2:17-24, 2003. Abstract BACKGROUND: Osteochondritis dissecans of the knee is a challenging clinical problem. We previously reported on the early successful results of autologous chondrocyte transplantation for the treatment of focal cartilage defects. The purpose of the present study was to assess the intermediate to long-term results of this technique in a large group of patients with osteochondritis dissecans. METHODS: Fifty-eight patients with radiographically documented osteochondritis dissecans of the knee underwent treatment with autologous chondrocyte transplantation between 1987 and 2000 and were assessed clinically with use of standard rating scales. Twenty-two patients consented to arthroscopic secondlook evaluation of graft integrity. RESULTS: The mean age of the patients at the time of autologous chondrocyte transplantation was 26.4 years (range, fourteen to fifty-two years). Seven patients were less than eighteen years old. Thirtyfive patients (60%) had juvenile-onset disease, and forty-eight patients (83%) had had a mean of 2.1 prior operations. The defect was located on the medial femoral condyle in thirty-nine patients and on the lateral femoral condyle in nineteen. The mean lesion size was 5.7 cm (2) (range, 1.5 to 12.0 cm (2) ), and the mean defect depth was 7.8 mm (range, 4 to 15 mm). After a mean duration of follow-up of 5.6 years, 91% of the patients had a good or excellent overall rating on the basis of a clinician evaluation and 93% had improvement on a patient self-assessment questionnaire. The Tegner-Wallgren, Lysholm, and Brittberg-Peterson VAS scores were all improved. The macroscopic quality of graft integrity averaged 11.2 on a 12-point scale, with only one graft having a score of <9 points. Two patients had a failure of treatment in the early postoperative period. Only one patient who had had a good or excellent rating at two years had a decline in clinical status at the time of the latest follow-up. CONCLUSIONS: Treatment of osteochondritis dissecans lesions of the knee with autologous chondrocyte transplantation produces an integrated repair tissue with a successful clinical result in >90% of patients. We recommend the wider use of autologous chondrocyte transplantation for this condition. <37> Unique Identifier 10709593 Authors Sales de Gauzy J. Mansat C. Darodes PH. Cahuzac JP. Institution Department of Pediatric Orthopaedic Surgery, Centre Hospitalier Universitaire de Toulouse, France. Title Natural course of osteochondritis dissecans in children. Source Journal of Pediatric Orthopaedics, Part B. 8(1):26-8, 1999 Jan. Abstract Results are reported from an absence of physiotherapic, orthopaedic, or surgical treatment in 31 cases of osteochondritis dissecans in 24 children. The mean age at diagnosis was 11 years and 4 months, and all the children were suffering from pain for an average of 3 months. None of these children were treated, except for instructions to discontinue involvement in sports activities until their pain had disappeared. In all cases pain disappeared, and these children have all returned to their former activities. According to x-ray findings, 30 lesions disappeared totally, although there was one case of a loose body. As a result, absence of treatment is recommended for osteochondritis dissecans in children. <38> Unique Identifier 10513356 Authors Hefti F. Beguiristain J. Krauspe R. Moller-Madsen B. Riccio V. Tschauner C. Wetzel R. Zeller R. Institution Department of Pediatric Orthopedics, University of Basel, Universitaetskinderspital beider Basel, Switzerland. Title Osteochondritis dissecans: a multicenter study of the European Pediatric Orthopedic Society. Source Journal of Pediatric Orthopaedics, Part B. 8(4):231-45, 1999 Oct. Abstract To assess of the value of conservative and operative treatment of osteochondritis dissecans of the knee, a multicenter study was performed. In 12 European countries, 798 cases of osteochondritis of the knee have been collected from 44 hospitals. Results were based on 452 patients with 509 affected knees with minimum follow-up was 1 year (mean follow-up, 3 years and 11 months) and sufficient data for evaluation: 61% were male patients; 39% female patients; 318 affected knees were found in juvenile patients; 191 affected knees were in adult or premature patients. The localization was the medial femoral condyle on the lateral side in 51% (typical site) of patients. Various other sites were involved. Of the 509 affected knees, 154 were treated conservatively, 355 were treated surgically (many with multiple operations). For evaluation, the initial situation (at the time of the diagnosis) was favorable in 198 patients (no effusion, diameter of the lesion < 20 mm and no gross dissection on imaging) and unfavorable (one of the parameters did not meet these prerequisites) in 311 patients. The results were better in young patients than in adult patients. However, in the adolescent group, 22% of patients had abnormal knee at followup. The classical localization has a better prognosis than an unusual one. Patients with a favorable situation at diagnosis have significantly better results after conservative treatment than those who have undergone operation. When there are signs of dissection, the results are better after operative than after conservative treatment. <39> Unique Identifier 8989704 Authors Aparicio G. Abril JC. Calvo E. Alvarez L. Institution Department of Pediatric Orthopaedic Surgery, Fundacion Jimenez Diaz, Madrid, Spain. Title Radiologic study of patellar height in Osgood-Schlatter disease. [Review] [14 refs] Source Journal of Pediatric Orthopedics. 17(1):63-6, 1997 Jan-Feb. Abstract There are contradictory reports regarding patellar position in the OsgoodSchlatter disease. We present a prospective statistical study of 17 patients with Osgood-Schlatter disease and 12 adolescents without anterior knee pain. The Caton-Deschamps index was assessed on strictly the lateral radiograph of the knee. The findings indicate a strong association between Osgood-Schlatter disease and patella alta. This increase in patellar height would require an increase in the force needed from the quadriceps to achieve full extension. This mechanism could be responsible for the apophyseal lesion. [References: 14] <40> Unique Identifier 11433172 Authors Hirano A. Fukubayashi T. Ishii T. Ochiai N. Institution Department of Orthopaedic Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba City, Ibaraki, and Tokyo University, Tokyo, Japan. Title Relationship between the patellar height and the disorder of the knee extensor mechanism in immature athletes. Source Journal of Pediatric Orthopedics. 21(4):541-4, 2001 Jul-Aug. Abstract SUMMARY: The purposes of this study were to evaluate the outcome of longitudinal research on the patellar height of immature athletes, and to clarify the relationship with disorders of the knee extensor mechanism. The patellar height of 40 young male soccer players (80 knees) was observed with radiographs of the bilateral knee joint for 2 years. The patellar height was measured using the epiphyseal line method. No subject showed patella alta before the occurrence of the disorder. Of the 12 knees in which the disorder occurred during the observation period, 10 knees (83%) had higher patella after the onset of symptoms than before. The patellar height in the painful stage was considered significant compared with the normal group. Although the patellar position in the predisorder stage was relatively high, this state was considered within the normal scope of physiologic variation, such as the growth spurt. <41> Unique Identifier 12548449 Authors Louisia S. Beaufils P. Katabi M. Robert H. French Society of Arthroscopy. Institution Service de Chirurgie OrthopediqueHospital Andre Mignot, Rue de Versailles, 78150, Le Chesnay, France. Title Transchondral drilling for osteochondritis dissecans of the medial condyle of the knee. Source Knee Surgery, Sports Traumatology, Arthroscopy. 11(1):33-9, 2003 Jan. Abstract Osteochondritis dissecans is a rare condition which occurs most frequently in the medial condyle of the knee. Its prognosis remains controversial. We report our experience with transchondral drilling (TCD) for osteochondritis dissecans. The rationale for this low-morbidity procedure is to enhance the healing potential of a lesion which failed to heal after conservative treatment. This multicenter retrospective study examined 24 patients (25 medial condyles), including cases both before (juvenile osteochondritis dissecans, JOCD; n=17) and after closure of the physis (adult osteochondritis dissecans, AOCD; n=8). All patients initially underwent a prolonged conservative treatment. The mean duration of symptoms prior to surgery was 22 months in JOCD and 55 months in AOCD patients. TCD was proposed in cases of intact or almost intact articular cartilage and was initially conducted under arthrotomy and later by arthroscopy. Mean follow-up time was 11.8 years in JOCD and 6 years in AOCD, and evaluation was based on clinical examination and radiography. Excellent clinical results were only observed in the JOCD group (12/17). In the AOCD group 4 patients had a good result and the other 4 a poor result. Radiological findings matched with clinical results. Except for age, factors of poor prognosis were: fissure of the articular cartilage and anterior extension of the lesion. We do not recommend TCD for AOCD. In JOCD, failure after 12 months of conservative treatment should indicate TCD in the cases where the cartilage remains continuous. At this stage there is no indication for more aggressive procedures. <42> Unique Identifier 12355306 Authors Kivisto R. Pasanen L. Leppilahti J. Jalovaara P. Institution Division of Orthopedic of Surgery, University of Oulu, Kajaanintie 52, 90220 Oulu, Finland. Title Arthroscopic repair of osteochondritis dissecans of the femoral condyles with metal staple fixation: a report of 28 cases. Source Knee Surgery, Sports Traumatology, Arthroscopy. 10(5):305-9, 2002 Sep. Abstract In a retrospective clinical study we evaluated the outcome of arthroscopic repair of osteochondritis dissecans (OCD) of the femoral condyles with metal stable fixation. Twenty-eight knees of 26 patients (mean age 20 years) with OCD of the knee were treated by fixation of the fragments with Hoffmann's dynamic metal staples arthroscopically and by additional arthrotomy in 7 knees. At follow-up (mean 4 years, 1-7) patients were interviewed for any residual symptoms and underwent a routine clinical and radiographic examination. The clinical results were based on the grading scale of Lysholm. The 17 knees which did not require further surgery showed 13 instances of complete healing, 3 of partial healing, and 1 of nonhealing. The 11 knees which had reoperations showed 2 instances of complete healing, 5 of partial healing, and 4 nonhealing. There was no significant difference between early or late surgery, and results were not related significantly to site of the lesion, handling of the fragment and the crater, percutaneous drilling, or type of fragmentation. Clinical grading of 13 knees was as excellent, 11 good, and 4 fair. Broken stables were observed in 9 knees, and they were removed from 5 knees. Complete healing was thus achieved in one-half and partial healing in one-third of cases. The metal staples used here fit for use in the arthroscopic fixation of the OCD of the knee, although the staples had a marked liability to break. <43> Unique Identifier 10639653 Authors Bruns J. Luessenhop S. Lehmann L. Institution Department of Orthopedic Surgery, University of Hamburg, Germany. j.bruns@uke.uni-hamburg.de Title Etiological aspects in osteochondritis dissecans patellae. Source Knee Surgery, Sports Traumatology, Arthroscopy. 7(6):356-9, 1999. Abstract In a retrospective study probable etiological factors of rare cases of osteochondritis dissecans of the patella were analyzed. Anamnestic data and data obtained from standardized roentgenography in the anterior-posterior, axial, and lateral views of the patella were evaluated. Anamnestic data provided no evidence of the etiology in addition to the fact that several patients mentioned a single or multiple trauma. In contrast to this, evaluation of the roentgenograms showed that most of the patients with osteochondritis patellae exhibited a flat articular surface of the patella (types I and V in Hertel's classification) and a distinct accumulation of the patellae with greater lateral than medial facet (types II and III in Wiberg's classification). Furthermore, the axial shape of the patellar groove exhibited a distinct accumulation of type III trochleae, representing a hypoplasia of the medial and hyperplasia of the lateral part of the trochlea. Evaluation of the lateromedial patellar alignment revealed in a distinct accumulation of grade II dislocation medially and laterally. Although the data were obtained from a rather small number of patients, in our opinion these results support the theory of biomechanical induction of osteochondritis dissecans patellae. Further dynamic analyses are needed to clarify biodynamic effects on the patella and the patellofemoral joint. <44> Unique Identifier 10819918 Authors Hinshaw MH. Tuite MJ. De Smet AA. Institution Department of Radiology, University of Wisconsin Hospital and Clinics, Madison, Wisconsin 53792-3252, USA. Title "Dem bones": osteochondral injuries of the knee. [Review] [30 refs] Source Magnetic Resonance Imaging Clinics of North America. 8(2):335-48, 2000 May. Abstract MR imaging plays a valuable role in the diagnosis and staging of osteochondral injuries of the femorotibial joint. Bone contusions may be the source of a patient's pain, and MR imaging characteristics of certain types may help to predict which contusions might progress to more serious osteochondral lesions. MR imaging also is vital in the diagnosis of occult osteochondral fractures and in accurately classifying displaced intra-articular fractures. Although osteochondral dissecans usually is diagnosed radiographically, MR imaging is the best noninvasive test for determining if an osteochondral fragment is unstable. Unstable lesions are a treatable cause of knee pain. [References: 30] <45> Unique Identifier 12974484 Authors Wall E. Von Stein D. Institution Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. eric.wall@cchmc.org Title Juvenile osteochondritis dissecans. [Review] [86 refs] Source Orthopedic Clinics of North America. 34(3):341-53, 2003 Jul. Abstract JOCD has better potential for healing than adult OCD, but several series have shown up to a 50% failure to heal with nonsurgical techniques. JOCD poses a therapeutic dilemma for the pediatric sports specialist because the healing potential is unpredictable at the disease onset. There are no controlled prospective studies on this condition to accurately gauge the effect of different treatments, or even if treatment affects the natural history of JOCD. [References: 86] <46> Unique Identifier 8848747 Authors De Smet AA. Ilahi OA. Graf BK. Institution Department of Radiology E3/311, University of Wisconsin Hospital, Madison 53792, USA. Title Reassessment of the MR criteria for stability of osteochondritis dissecans in the knee and ankle. Source Skeletal Radiology. 25(2):159-63, 1996 Feb. Abstract OBJECTIVE. T2-weighted MR images has been reported to be an accurate method for assessing osteochondritis dissecans. We reviewed our MR experience to confirm the accuracy of the published criteria of instability. We also assessed the value of each of four MR signs of instability. DESIGN. We reviewed the original MR interpretations, arthroscopic reports, and MR examinations of 40 patients with osteochondritis dissecans of the talar dome or femoral condyles. Arthroscopy was used as the gold standard for stability. The MR examinations were reviewed retrospectively for a high-signal-intensity line or cystic area beneath the lesion, a high-signal-intensity line through the articular cartilage, or a focal articular defect. PATIENTS. All patients who had undergone MR imaging for osteochondritis dissecans from 1990 to 1993 were reviewed. Forty patients were identified who had arthroscopy after the MR examination. There were 30 male and 10 female patients with an average age of 25.7 years. Thirtyone lesions were in femoral condyle and nine were in the talar dome. RESULTS AND CONCLUSIONS. The original MR interpretations correctly identified 35 of the 36 unstable lesions and all 4 stable lesions, giving a sensitivity of 0.97 and specificity of 1.0. There was a 98% agreement between the original and retrospective diagnoses. A high-signal-intensity line was seen beneath 72% of the 36 unstable lesions. The other three signs were noted in 22-31% of the unstable lesions. Fifty-six percent of the unstable lesions showed only one sign of instability. MR imaging is a highly sensitive method for detection of unstable osteochondritis dissecans. The presence of any one sign indicates instability, the most frequent sign being an underlying high-signal-intensity line. Because we examined only four stable lesions, our 95% confidence interval of 0.40-1.0 for a specificity of 1.0 gives only a limited estimate of the specificity of MR.