CURRICULUM VITAE Email:Ghaffarieh@wisc.edu NAME: Alireza, Ghaffarieh(Ghaffariyeh) Education and Degrees: Shiraz University of Medical Sciences, Medical School, Shiraz, Iran 1988-1996 Internship: Shiraz University of Medical Sciences, affiliated hospitals, Shiraz, Iran September 1994-1995 Residency: Shiraz University of Medical Sciences, Medical School, Shiraz, Iran 1998-2002 Certification: Iranian Board Certified in Ophthalmology Ocular physiotherapy, Amblyopia Therapy and Low Vision rehabilitation in Fyodorov Eye institute 2007, Krasnove eye Institute 2008, Moscow, Russia, Research fellowship in Ophthalmology and Visual Science in University of Wisconsin 2011 Academic Career Assistant Professor of Ophthalmology and Head of Department of Ophthalmology Fasa Medical School 2002-2004 Affiliate scientist in New Mexico University, Artificial Muscle Research institute since 2005 Affiliate scientist in Maine University, Biomechanical Engineering Department, Robotic eye surgery since 2011 Editorial Board Member of world ophthalmology journal Editorial Advisory Board of the Journal of Symptoms and Signs Editorial Board member of Pharmacologia Editorial Board - International Scholars Journals Reviewer of of American Journal of Ophthalmology 1 Reviewer of Ophthalmic Surgery, Lasers & Imaging journal Reviewer of Journal of Pediatric Ophthalmology & Strabismus Reviewer of Journal of Refractive Surgery Reviewer of Clinical Chemistry and Laboratory Medicine Reviewer of Cell & Tissue Banking Reviewer of BMC Ophthalmology Reviewer of Middle East African Journal of Ophthalmology Reviewer of Neural Regeneration Research Reviewer of Africa Journal of Pharmacy and Pharmacological Research Reviewer of Africa Journal of Biotechnology Reviewer of Journal of Medical Hypotheses and Ideas International member of American Academy of Ophthalmology (AAO) Member of Medical Council of Iran and Iranian Ophthalmology Society Member board the MEACRS (MEACO Subspecialty Society) Consultant ophthalmologist at Dr Khodadoust Eye Hospital Head of Department of Ophthalmology in Kowsar Hospital Founder of first low vision rehabilitation center in the south of Iran Research Interest: Experimental ophthalmology, ocular pathology, robotic surgery, biomaterial and tissue engineering, biomechanics, Molecular biology 2 HONOURS First class and level in high school examination Top 1-% among medical school graduates of Shiraz University of Medical Sciences Publication Effect of transcutaneous electrical stimulation on rabbit corneal epithelial cell migration.Ghaffarieh A, Ghaffarpasand F, Dehghankhalili M, Honarpisheh N, Nirumandi S, Tanideh N. Cornea. 2012 May;31(5):559-63. 1. Saccade movements effect on the intravitreal drug delivery in vitreous substitutes: a numerical study .Amirreza Modareszadeh, Omid Abouali, Alireza Ghaffarieh ,Goodarz Ahmadi. Biomechanics and Modeling in Mechanobiology, Online First™, 12 May 2012 2. Investigation of Saccadic Eye Movement Effects on the Fluid Dynamic in the Anterior Chamber. Abouali O, Modareszadeh A, Ghaffarieh A, Tu J Accepted for publication in Journal of Biomechanical Engineering Journal 2012 3. Numerical simulation of the fluid dynamics in vitreous cavity due to saccadic eye movement.Abouali O, Modareszadeh A, Ghaffariyeh A, Tu J. Med Eng Phys. 2012 Jul;34(6):681-92. 4. Novel PDMS-based membranes: Sodium chloride and glucose permeability . Naeimi M., Karkhaneh A., Barzin J., Khorasani M.T., Ghaffarieh A. Journal of Applied Polymer Science Article first published online: 24 MAY 2012 3 4. Simulation of flow field during irrigation/aspiration in phacoemulsification using computational fluid dynamics.Abouali O, Bayatpour D, Ghaffariyeh A, Ahmadi G. J Cataract Refract Surg. 2011 Aug;37(8):1530-8. 5. Possible Pathogenic Role of Brain Derived Neurotrophic Factor (BDNF) in Glaucoma-like optic neuropathy in patients with intracranial tumours. Ghaffariyeh A, Honarpisheh N. Acta Ophthalmol. 2011 89(5):e475; 6. Discussion on IOL optic malposition. Ghaffariyeh A, Fuad Abasov, Nazafarin Honarpisheh, Behruz Maleki. Optometry 2011 ; 82(3):131. 7. BDNF as biomarker in primary open angle glaucoma. Ghaffariyeh A, Honarpisheh N ,Heidari MH, Puyan S, Abasov F . Optom Vis Sci. 2011 ;88(1):80-5. 8. Fyodorove juev keratoprosthesis: Long term results in patients with multiple failed corneal grafts. Ghaffariyeh A, Honarpisheh N, Karkhaneh A, Abudi R , Moroz ZI, Peyman A, Faramarzi A, Abasov F. Graefes Arch Clin Exp Ophthalmol. 2011 ;249(1):93-101. 9. Supra-descemet's fluid drainage with simultaneous air injection; an alternative treatment for descemet's membrane detachment (DMD). Ghaffariyeh A, Honarpisheh N, Tooraj Chamacham. Middle East Afr J Ophthalmol. 2011 Apr;18(2):189-91. 10. Novel materials to enhance Corneal Epithelial Cell Migration on keratoprosthesis. Karkhaneh A, Mirzadeh H, Ghaffariyeh A ,Ebrahimi A, Honarpisheh N, Hosseinzadeh M, Heidari MH. Br J Ophthalmol. 2011 ;95(3):405-9. 4 11.Detection of Chlamydia trachomatis in the subretinal fluid of a patient with rhegmatogenous retinal detachment. Ghaffariyeh A, Honarpisheh N, Lari AR. Clin Exp Optom. 2011 Sep;94(5):488-9. 12.Novel material to quantify sharpness and traction of vitreous cutters Alireza Ghaffariyeh, Nazafarin Honarpisheh, Akbar Karkhaneh and Fuad Abaso J Med Hypotheses Ideas, 2011, 5:7 13. Physicomechanical Consideration for prevention of in the bag IOL dislocation following uncomplicated phacoemulsification. Ghaffariyeh A, Abouali O, Honarpisheh N. Clin Exp Optom. 2010 93(4):271-2. 14. Magnet- assisted Capsular Bag Fixation to manage limited Zonular Dialysis during Phacoemulsification. Ghaffariyeh A, Honarpisheh N. Ophthalmic Surg Lasers Imaging. 2010 2:1-3. 15.Sutureless Sulcus Fixation Ring to Prevent Intraocular Lens Dislocation in Zonular Weakness During Phacoemulsification. Alireza Ghaffariyeh, ,Nazafarin Honarpisheh,* ,Fuad Abasov. Tech Ophthalmology 2010;8: 140Y142 16. Amantadine-associated corneal edema. Ghaffariyeh A, Honarpisheh N. Parkinsonism Relat Disord. 2010 27. 17. Scleroplasty in progressive myopia. Balashova NV, Ghaffariyeh A, Honarpisheh N. Eye (Lond). 2010 Jan 15. 18. Application of hydraulics law for prediction of endothelial cells injury from infusion turbulence. Ghaffariyeh A, Honarpisheh N. Cornea. 2010 29(1):121. 19. Novel theory for treatment of presbyopia: Rejuvenation of zonular fibers by capsular anterior annular peripheral shrinkage (CAPS). Ghaffariyeh A, 5 Shahinpoor M, Soltanpour D ,Honarpisheh N. Irn J Med Hypotheses Ideas, 2010, 4:12. 20. Brain-Derived Neurotrophic Factor (BDNF) in patients with Normal-Tension Glaucoma (NTG).Ghaffariyeh A, Honarpisheh N, Shakiba Y, Puyan S, Chamacham T, Zahedi F, Zarrineghbal M. Optometry 2009 80(11):635-8. 21. High Vitreous Urea Rebound in a Glaucoma Patient with Increased Intraocular Pressure during Hemodialysis. Ghaffariyeh A, Honarpisheh N, Pishva E. Can J Ophthalmol. 2009 44(5):e51. 22. Anterior Ciliary Artery Ligation with Simultaneous Intravitreal Bevacizumab; An Adjuvant Treatment for End Stage Neovascular Glaucoma. Ghaffariyeh A, Honarpisheh N. Acta Ophthalmol. 2009 Jun 24. 23. Evaluation of transcutaneous electrical simulation to improve recovery from corneal hypesthesia after LASIK. Ghaffariyeh A,Peyman A,Puyan S,Honarpisheh N, Bagheri B, Peyman M.Graefes Arch Clin Exp Ophthalmol. 2009 247(8):1133-8. 24. Tricyclic Antidepressants: Potential Therapeutic Alternatives for Treatment of Dry Eye Symptoms after LASIK. Ghaffariyeh A, Chamacham T . J Refract Surg. 2008 24(8):770-1. 25. Zonuloplasty" A novel surgical treatment for zonular weakness in patients undergoing cataract surgery. Ghaffariyeh A, Chamacham T. Iranian journal of medical hypotheses and ideas 2008, 2:8. 26. Effects of noxious compounds in exhaled breath air as a potential mechanism causing "Red eye" in renal failure patients. Ghaffariyeh A, Chamacham T . Iranian journal of medical hypotheses and ideas 2007 1:7. 6 27. Simultaneous graft polymerization of 2- Hydroxyethyl Methacrylate and acrylic acid onto polydimethylsiloxane surfaces using a two step plasma treatment. Karkhaneh A, Mirzadeh H, Ghaffariyeh A. Journal of applied polymer science ,vol 105,2007 2208-2217 . 28. Collagen immobilization onto HEMA grafted PDMS using plasma enhance epithelial cell attachment for corneal applications "Invitro and In vivo assays Karkhaneh A, Mirzadeh H, Ghaffariyeh A . International journal of artificial organs vol 30/no 8, 2007, pp687-664. 29. Noxious compounds in exhaled air, a potential cause for ocular manifestations of H. pylori gastrointestinal infection. Hosseini H, Ghaffariyeh A, Nikandish R. Med Hypotheses. 2007;68(1):91-3. 30. Stress perimetry: An Alternative for Early Detection of Open Angle Glaucoma in High Risk Population. Ghaffariyeh A, Honarpisheh N, Abasov F, Heidari MH journal of medical hypotheses and ideas 2011. 31. Diode Laser 810 nm as a potential treatment to improve visual function in Nonarteritic Anterior Ischemic Optic Neuropathy (NAION). Ghaffariyeh A, Honarpisheh N, Ghorbani Khebreh MR, Abasov F , Heidari MH. Iranian journal of medical hypotheses and ideas 2011, 5:3 . 32. Longitudinal tear flow study after cyclosporine in kidney allograft recipients.Mehryar M, Ghaffariyeh A, Honarpisheh. Bina journal of ophthalmology 9:2 2003. 33. Treatment of active toxoplasma chorioretinitis with diode laser .Mehryar M ,Ghaffariyeh A, Farvardin M, Kavian. BINA journal of ophthalmology 1:7 2002. 7 34-Two-step plasma surface modification of pdms with mixture of hema and aac: Collagen immobilization and in vitro assays A Karkhaneh, H Mirzadeh, AR Ghaffariyeh - Cell [0092-8674] Karkhaneh yr:2007 vol:1 pg:12 35-A randomized controlled trial of 5-day regimen of azithromycin and a 10-day regimen of co-amoxiclav for treatment of acute sinusitis . Lari A.R., Ghaffariyeh A., Etesam N., Mostafavi H., Alaghehbandan R. (2010) Iranian Journal of Clinical Infectious Diseases, 5 (3), pp. 137-141. Book Chapter: Book title: International Review of Neurobiology: Axon Growth and Regeneration: Part 1 Volume 105 Editors: Jeffrey L Goldberg and Ephraim F Trakhtenberg Chapter 1: Optic Nerve Disease and Axon Pathophysiology by Alireza Ghaffarieh and Leonard A. Levin Publisher: Elsevier Inc Publication date: December 2012 MD thesis” Benign cystic teratoma of ovary:a clinicopathological study in 50 cases International presentations 1-Evaluation of Cell Behavior on the Surface of HEMA/AAc-Collagen Immobilized PDMS by Plasma Treatment.8th World Biomaterials Congress, Amsterdam, The Netherlands, 2008. 2-Corneal Epithelial Layer Formation on the Molecular Engineered Silicone Surface as a New Artificial Cornea, 8th World Biomaterials Congress, Amsterdam, 8 The Netherlands, 2008. 3. LASIK in myopic patients with psoriasis. European society of cataract and refractive surgery, Berlin 2008. 4-Brain-derived neurotrophic factor (BDNF), a novel marker for therapeutic monitoring in glaucoma optic neuropathy. European society of cataract and refractive surgery Berlin 2008. 5-Application of Hydroelastic Fluid in Phacoemulsification. XXVI Congress of the ESCRS,Berlin, Germany, 2008. 6- Two-step Plasma Surface Modification of PDMS with Mixture of HEMA and AAc: Collagen Immobilization and In vitro Assay, 5th IASTED International Conference on Biomedical Engineering (BioMed 2007), Innsbruck, Austria. 7. Nano-spring implant for glaucoma treatment "European society of cataract and refractive surgery Stockholm 8-12 sep 2007. 8. Novel theory for glaucoma treatment (PAD): Polymer-Assisted Dilatation of Schlemm's canal "European society of cataract and refractive surgery Stockholm 812 sep 2007. 9. Zonuloplasty "ISRS/AAO Meeting 26-27 May Beijing, China 2007. 10.Novel theory for glaucoma treatment "MPAD" MAGNETIC POLYMER ASSISTED DRAINAGE "Sao Paulo, November 10th, The World Ophthalmology Congress - WOC 2006 Brazil. 11. Novel concept for treatment of iridocorneal endothelial syndrome with peripheral corneal laser photocoagulation "Sao Paulo, November 10th, The World 9 Ophthalmology Congress - WOC 2006 Brazil. 12.Application of electrostimulation in ophthalmology "Sao Paulo, November 10th, The World Ophthalmology Congress - WOC 2006 Brazil. 13. Internal filtering concept in glaucoma surgery "Sao Paulo, November 10th, The World Ophthalmology Congress - WOC 2006 Brazil. 14. Osteo odontal keratoprosthesis implantation "Sao Paulo, November 10th, The World Ophthalmology Congress - WOC 2006 Brazil. 15. Application of Scleroplasty for treatment of progressive myopia, 11th International Myopia Conference Singapore 2006. 16. Evaluation of Cell Behavior onto Collagen Grafted Poly (HEMA-co-MAA): In Vitro"6th KPro Study Group Meeting, Miami, Florida, USA 6 May 2006. 17. Capsular anterior annular shrinkage (CAPS) theory for treatment of presbyopia "Middle East African council of ophthalmology (MEACO) 2006 UAE. 18- Modareszadeh, O. Abouali and A. Ghaffariyeh, “CFD Analysis Of Nano-Drug Transport In Vitreous Cavity Due To Saccadic Eye Movements” The 9th International ASME Conference on Nanochannels, Microchannels and Minichannels, ICNMM2011, Edmonton, Canada, June 2011. Volume 1, pp. 27-33. DOI: 10.1115/ICNMM2011-58251 10 MD& MS& PhD Thesis with Medical, Biomechanic and Biomaterial Students 1-Effect of heparin in post-operative inflammation after cataract surgery 2-Manual Phacosection, (Method & Complications) 3-IOP change after manual Phacosection and phacoemulsification 4-Screening for open angle glaucoma in FASA population 5- Study the toxicity of intracameral xylocaine in rabbit corneal endothelium 6. Two-step Plasma Surface Modification of PDMS with Mixture of HEMA and AAc: Collagen Immobilization and In vitro and In vitro Assay 7. Numerical Simulation of Fluid Dynamic in Vitreous Chamber Due to Saccadic Eye Movement 8. 3-D Numerical Study for Different Types of Irrigation/Aspiration in Phacoemulsification of Human Eye 9. Fluid Dynamic for Various Viscosities of Irrigating Solutions in Phacoemulsification of Human Eye Journal submission under review 1- High glucose and diabetes modulate the proteasome function Saeed Y. Aghdam, Zafer Gurel, Alireza Ghaffarieh1, Christine M. Sorenson, Nader Sheibani 2.Theoretical Study the Fluid Viscosity Effect on the Cornea During 11 Irrigation/Aspiration in Phacoemulsification 3-Physiology of Aqueous Humor Dynamic in the Anterior Chamber Due to Rapid Eye Movement 4-Analysis of Deformation of Human Cornea During Irrigation/Aspiration in Phacoemulsification US Patent 1. BDNF AS BIOMARKER IN GLAUCOMA. Patent application number: 20100003707 2. SULCUS SUPPRTED CAPSULAR TENSION RING Patent application number: 13304370 3. INTRAOCULAR LENS WITH ASYMMETRIC HAPTICS US Provisional Patent Number: 61112721 4. APPLICATION OF HYDROELASTIC FLUID IN PHACOEMULSIFICATION. US Provisional Patent Number: 61079559 5. MAGNET ASSISTED CAPSULAR FIXATION RING DEVICE AND METHOD US Provisional Patent Number: 61114064 Languages Turkish, Farsi, English 12 Extra-curricular activities Environmental activist to save Lake Urmia. Lake Urmia, the largest lake in the Middle East and one of the environmental wonders of the world, is registered as Biosphere Reserve by UNESCO. Over the last several years, Lake Urmia has shrunk significantly and its depth has fallen by seven meters. According to experts, if the lake completely dries up, a vast amount of salt will be released into the atmosphere resulting in an ecological catastrophe not only in Azerbaijani cities of Iran but also, in neighboring countries such as Turkey and Azerbaijan. REFERENCES 1-Ali Aminlari M.D., F.A.C.S. Professor of ophthalmology, Penn State University, Hershey, PA 17033,USA aliaminlari@yahoo.com 2-Reza Dana, MD, MPH, MSc Claes Dohlman Professor of Ophthalmology Director, Cornea Service, Mass. Eye & Ear Infirmary Senior Scientist & W Clement Stone Scholar, Schepens Eye Research Inst. Associate Chief of Ophthalmology and Vice Chair for Academic Programs Harvard Department of Ophthalmology Phone: 617-912-7401 Fax: 617-912-0117 http://www.eri.harvard.edu/faculty/dana 3. Aliasghar Khodadoust ,MD, Professor of Ophthalmology, Yale Eye Center, 330 Cedar Street, Boardman Building 110, New Haven, CT 06520 Office Phone: (203) 785-2020 13 Fax: (203) 785-7694 4. Mohsen Shahinpoor, Ph.D., PE, Richard C. Hill Professor Chair, Mechanical Engineering Department University of Maine, USA Mailing Address Mohsen Shahinpoor Department of Mechanical Engineering 5711 Boardman Hall, Room 219A University of Maine Orono, ME 04469-5711 Telephone: 207-581-2143 Fax: 207-581-2379 Email: mohsen.shahinpoor@maine.edu 5. Christopher Liu Consultant Ophthalmic Surgeon, Sussex Eye Hospital, and Honorary Clinical Senior Lecturer, Brighton and Sussex Medical School, England, and Kinki University, Osaka, Japan Email: cscliu@aol.com 14