Stem Cell (Journal)

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Chi-Wei Lu, Ph.D.
Assistant Professor
Department of Obstetric, Gynecology and Reproductive Sciences
Director, Human Embryonic Stem Cell Core Facility
University of Medicine and Dentistry of New Jersey,
663 Hoes Lane West, RM126
Piscataway NJ08854
Phone: 732-235-2870
Email: [email protected]
Education and Training
Harvard Medical School, Boston, Massachusetts
Whitehead Institute for Biomedical Research
University of Medicine and Dentistry of New Jersey
/Rutgers University, Piscataway, New Jersey
National Taiwan University, Taipei, Taiwan
post-doctoral
post-doctoral
Ph.D.
2003-2007
2002-2003
1996-2002
B.S.
1990-1994
Professional Experience
Assistant Scientist, McKnight Brain Institute,
University of Florida, Gainesville FL
Research assistant, Academia Sinica, Taipei, Taiwan
2007-2008
1994-1996
Awards and Honors
Ellison Medical Foundation New Scholar Award, 2009
Living Free for Research Foundation Young Investigator Award, 2008
Keystone Symposia Educational Fund Scholarship, 2007
Best Poster Award, International Society for Stem Cell Research Meeting 2006
Georgeanna Seegar Jones Young Investigator Award, 2006
Professional Affiliations
International Society for Stem Cell Research (ISSCR)
American Association for Cancer Research (AACR)
Publications
• Chen LY, Yabuuchi A, Eminli S, Takeuchi A, Lu CW, Hochelinger K and Daley GO (2009) Cross-regulation
of Nanog and Cdx2. Cell Research, in press
• Viswanathan SR, Mermel CH, Lu J, Lu CW, Golub TR and Daley GQ (2009) MicroRNA expression during
trophectoderm specification. PLoS One, in press
• Chi-Wei Lu, Lingyi Chen, Akiko Yabuuchi, Srinivas Viswanathan, Kitai Kim and George Q. Daley (2008)
Ras-Mitogen Activated Protein Kinase Signaling Promotes Trophectoderm Lineage Establishment. Nature
Genetics Jul; 40(7)921-6
• Kyba M, Perlingeiro RC, Hoover RR, Lu CW, Pierce J, Daley GQ. (2003) Enhanced hematopoietic
differentiation embryonic stem cells conditionally expressing Stat5. PNAS 100 Suppl. 1 11904-11910
• Lu CW and Roth MJ (2003) The Role of Q252R in activating membrane fusion in the murine
leukemia virus surface envelope protein. J.Virol. 2003, Oct; 77(20): 10841-9.
• Lu CW and Roth MJ (2003) Functional Interaction between the N- and C-terminal domains of murine
leukemia virus surface envelope protein. Virology 310(1):130-40
• Lu CW , O’Reilly and Roth MJ (2003) G100R mutation within 4070A murine leukemia virus Env
increases virus receptor binding, kinetics of entry, and viral transduction efficiency. J Virol. 77(1):739-43.
• Lu CW and Roth MJ (2001) Functional characterization of the N termini of murine leukemia
virus envelope proteins. J Virol. (9):4357-66.
• Lin JS, Lu CW, Huang CJ, Wu PF, Robinson D, Kung HJ, Chi CW, Wu CW, Yang WK,
Whang-Peng JJ, Lin WC. (1998) Protein-tyrosine kinase and protein-serine/threonine kinase expression
in human gastric cancer cell lines. J Biomed Sci. 5(2):101-10.
Invited Presentations:
Keystone Symposium on Reproduction: Advances and Challenges, New Mexico, 2007
Center for Regenerative Medicine, University of Connecticut, Oct 2006
Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, June 2006
Center for Genomic Research, Academia Sinica, Taipei, Taiwan, June, 2006
Division of Medical Research, Chang-Gang memorial Hospital, Kaohsiung, Taiwan 2006
The Activated Egg Symposium, Bedford Research Foundation, Newton, MA, Oct 2005
Harvard Stem Cell Institute Meetings; Boston, MA Sep. 2005
Sun-Tien Pharmaceuticals; Taipei, Taiwan May 2004
Reviewer for:
Stem Cell (Journal)
Wellcome Trust (Grant)
Current Support:
• New Jersey Commission on Science and Technology Stem Cell Initiative: Bioengineering Human
ES Stem Cells, Program project P.I: Monica Roth: Project 2 “Bioengineering hES cells into
oligodendrocytes”, role: P.I. (effective 10/2008) Total cost (project 2), $300,000, 07/01/07-06/30/10.
This project develops the differentiation of hES cells toward oligodendrocytes, the myelin-forming
cells of the central nervous system.
• New Jersey Commission on Science and Technology Stem Cell initiative: Bioengineering Human
ES Stem Cells, Program project P.I: Monica Roth: Core A “Human embryonic stem cell core facility”,
role: director (effective 10/2008) Total cost (project 2), $728,457, 07/01/07-06/30/10.
This core facility grants are to establish human embryonic stem cell laboratories on the
UMDNJ/RWJMS campus.
• Ellison Medical Foundation New Investigator Award: Increased Cancer Susceptibility in Aging
Tissue: An Embryonic Stem Cell Approach. Role: P.I. Total Cost, $400,000, 07/01/2009 – 06/30/2013.
Pending Support
NIH RC4
09/01/2010
Assembly of iPSCs from underrepresented population
Role: co-PI
$916,000.
This is a multi-PI project for the RFA: NIH Director’s Opportunity for Research in Five Thematic Areas.
NIH R21
12/01/2010
Placental complementation of a mouse model for Down syndrome.
Role PI
$415,442.
This project proposes to test placental complementation in an animal model of neuro-developmental disorder.
Goldberg Memorial Foundation for Cancer Research
7/1//2010
Retroviral Insertional Mutagenesis of Human Embryonic Stem Cells as a Model for Cancer
$25,000
Gates Foundaction: Grand Challenges
9/1/2010
Better Placenta for Healthier Babies
$100,000
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