BME5: Introduction to Biotechnology Wendy Rothwell, Ph.D. (Rothwell-Lopez) rothwell@soe.ucsc.edu Office Hours: 9:45-10:45am MWF in 405A PSB Office Phone: (831) 459-1623 Spring 2009 MWF 8:00 am-9:10 am Classroom Unit 1 Course Description Lecture course providing an introduction to the tools and applications of biotechnology in the fields of medicine, agriculture, the environment and industry. TA and Discussion Sections not mandatory, TA TBA Section Class # Day 01A 75221 Th 01B 75223 F Time 4:00-5:10pm 11:00am-12:10pm Location Engineer 2 194 Engineer 2 194 Text and other sources Text: Introduction to Biotechnology second edition, Thieman and Palladino (2009) (available on reserve in the Science and Engineering library) Companion website (Bookmark this!): http://wps.aw.com/bc_palladino_biotech_2/ WebCT account: see WebCT Instructions at the end of the syllabus. National Center for Biotechnology Information (NCBI): http://www.ncbi.nlm.nih.gov/ Grading Grades will be based on performance on 8 homework assignments (lowest score of 9 dropped), 2 exams and one research paper describing a newly developed biotechnology approach or tool. Weighting of each component in the grade is shown below. assignment Homework Exams Paper* number 8 2 1 points each 10 50 20 total points 80 100 20 200 % of grade 40% 50% 10% * Please refer to the Paper Handout (available on WebCT) for details regarding format, etc. Note*** add 5 points extra credit if all 9 homework assignments are turned in. Homework assignments are due every Monday at the start of class. (when Monday is a Holiday, the assignment is due on the following Wednesday) The final exam is not comprehensive and will be given on Tuesday, June 9 from 8:00-11:00am in Classroom Unit 1. I don’t expect to grade on a curve although I’ll wait until I see the final scores to make that assessment. I will not, however, pass anyone who earns fewer than 60% of the total points. Course Organization As I give the lectures I will be filling in lecture outlines that have been previously prepared. Copies of each of these outlines will be made available on the WebCT course Website prior to each lecture and will be formatted such that students can fill them in with the information as I lecture. Therefore, it will be important for students to have these printed out and ready to fill in at the start of each lecture. Whenever possible I will use figures from your text in my lectures. However, on many occasions I will be using other sources from the Web and I may also utilize handouts. Links to the Web sources will be provided within the text in each lecture outline. Handouts, if I use them, will be made available on the WebCT course Website. Exams The format of the exams will include short answer, matching, true-false and multiple choice questions. No scantrons or bluebooks will be needed. Also, no electronic devices (calculators, etc) will be needed or allowed. Bring 2 sharp pencils with erasers. No make-up exams will be provided. Therefore, you may want to give yourself extra time to get to school on exam days (in case something happens on the way to school). Disability Resource Center (DRC) Accommodations Anyone needing DRC accommodations needs to let me know, and submit an Accommodation Authorization as early in the quarter as possible in order to ensure enough time to set up the accommodations. Contact DRC at 459-2089 (voice), 459-4806 (TTY). Academic Integrity Behaviors considered to constitute academic misconduct (cheating, plagiarism, or aiding others in cheating) will be taken very seriously and will result in anything from a zero score on the assignment to failing the class. The “Official University Policy on Academic Integrity” can be found at http://www.ucsc.edu/academics/academic_integrity/undergraduate_students/ Note that plagiarism means the act of presenting someone else’s words/ideas as your own. This involves not only taking text, word-for-word from another source but also includes moving words around to make a “new” set of sentences based on someone else’s text = paraphrasing. Failing to reference the source of findings described within a publication is another form of plagiarism. Excellent information regarding plagiarism, what it is and how it can be avoided can be found at: Indiana University Writing Tutorial Services. I urge you all to visit this site. http://www.indiana.edu/~wts/pamphlets/plagiarism.shtml#plagiarized Lecture Schedule (subject to change with fair notice) Reading assignments for each lecture are noted at the start of each lecture outline (available on the WebCT course website) 3/30 (Mon): The History, Promise and Challenges of Biotechnology (Lecture 1) 4/1 (Wed): Lecture 1 continued 4/3 (Fri): Genes, Genomes, Chromosomes and Cells (Lecture 2) 4/6 (Mon): Lecture 2 continued 4/8 (Wed): Lecture 2 continued 4/10 (Fri): Recombinant DNA Technology and PCR (Lecture 3) 4/13 (Mon): Lecture 3 continued 4/15 (Wed): Lecture 3 continued 4/17 (Fri): Producing and Isolating Proteins (Lecture 4) 4/20 (Mon): Lecture 4 continued 4/22 (Wed): Microbial Biotechnology (Lecture 5) 4/24 (Fri): Lecture 5 continued 4/27 (Mon): Lecture 5 continued 4/29 (Wed): Lecture 5 continued 5/01 (Fri): Engineering Plants and Animals (Lecture 6) 5/04 (Mon): Exam 1 (covers information through 4/29 lecture) 5/06 (Wed): Lecture 6 continued 5/08 (Fri): Lecture 6 continued 5/11 (Mon): Biotechnology and the Environment (Lecture 7) 5/13 (Wed): Aquatic Biotechnology (Lecture 8) 5/15 (Fri): Medical Biotechnology I: Diagnosis and Treatment of Disease (Lecture 9) 5/18 (Mon): Lecture 9 continued 5/20 (Wed): Lecture 9 continued 5/22 (Fri): Lecture 9 continued 5/25 (Mon): Holiday 5/27 (Wed): Medical Biotechnology II: Regenerative Medicine and Bioethics (Lecture 10) 5/29 (Fri): Lecture 10 continued 6/01 (Mon): Lecture 10 continued 6/03 (Wed): Lecture 10 continued 6/05 (Fri): Biotechnology Regulation (Lecture 11) 6/09 (Tues): Final Exam (covers information from 5/01 lecture on) from 8:00-11:00am in Classroom Unit 1 WebCT Login Instructions Go to http://ic.ucsc.edu/services/learning_management_system/ Login to WebCT using the same user ID and password as the ones used for your campus email account. Note that you will not have access to the WebCT account if you are not registered for the class. Further instructions and help, if needed, can be obtained from the login guide (http://ic.ucsc.edu/services/learning_management_system/student_info.php) or by contacting me at rothwell@soe.ucsc.edu.