Curriculum Vitae

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謝俊民醫師之個人著作 (更新至 2015/04)
1. Jiunn-Min Shieh, Yen-An Tang, Tsung-Han Yang, Chih-Yi Chen, Han-Shui
Hsu, Yi-Hung Carol Tan, Ravi Salgia, Yi-Ching Wang. Lack of Association of
C-Met-N375S Sequence Variant with Lung Cancer Susceptibility and Prognosis.
Int.J.Med.Sci.2013; 10(8):988-994(I.F:2.24, ranking 35/153=23% on medicine,
general & internal)
2. Jiunn-Min Shieh, Yung-Chan Chen, Yin-Chao Lin, Jia-Ni Lin, Wei-Chih
Chen,Yang-Yuan Chen, Chi-Tang Ho, Tzong-Der Way. Demethoxycurcumin
Inhibits Energy Metabolic and Oncogenic Signaling Pathways through AMPK
Activation in Triple-Negative Breast Cancer Cells. J.Agric.Food Chem.2013, 61,
6366-6375. (I.F:2.82, ranking 3/57=5.3% on Agriculture, multidisciplinar)
3. Shian-Chih Ko*, Chi-Ruei Huang*, Jiunn-Min Shieh, Jhen-Hong Yang,
Wen-Chang Chang, Ben-Kuen Chen. Epidermal Growth Factor Protects
Squamous Cell Carcinoma against Cisplatin-Induced Cytotoxicity through
Increased Interleukin-1β Expression. PLOS one, 2013,8(2): e55795(I.F:4.09,
ranking 12/84=14% on Biology)
4. Jia-Yang Chen, Yen-An Tang, en-Shan Li, Yu-Ching Chiou, Jiunn-Min
Shieh*, Yi-Ching Wang*. A Synthetic Podopyllotoxin Devirative Exerts
Ant-Cancer Effects by Inducing Mitotic Arrest and Pro-Apoptotic ER Stress in
Lung Cancer Preclinical Models. PLoS one, 2013, April: e62082.
(Corresponding author) (I.F:4.09, ranking 12/84=14% on Biology)
5. Huey-Ming Lo, Jiunn-Min Shieh, Chih-Li Chen, Chih-Jen Tsou, Wen-Bin Wu.
Vascular Endothelial Growth Factor Induces CXCL1 Chemokine Release via
JNK and PI-3K-Dependent Pathways in Human Lung Carcinoma Epithelial
Cells. Int.J. Mol.Sci.2013,14, 10090-10106.
6. Jiunn-Min Shieh, T.-T. Wei, Y.-A. Tang, S.-M. Huang, W.-L. Wen, M.-Y. Chen, S.B.
Salunke, C.-T. Chen, C.-S. Chen, Y-C Wang. Mitochondrial apoptosis and FAK
signaling disruption by a novel histone deacetylase inhibitor, HTPB, in
antitumor and antimetastatic mouse models. PLoS
one, 2012,7(1): e30240. (I.F:4.09, ranking 12/84=14% on Biology)
7. Jiunn-Min Shieh, Tzu-Tang Wei, Yen-An Tang, Sin-Ming Huang, Wei-Ling
Wen, Mei-Yu Chen, Hung, Chi Cheng ,- Santosh B. Salunke, Ching-Shih Chen,
Pinpin Lin, Chien-Tien Chen, Yi-Ching Wang. Mitochondrial Apoptosis and
FAK Signaling Disruption by a Novel Histone Deacetylase Inhibitor, HTPB, in
Antitumor and Antimetastatic Mouse Models. PLoS one, 2012;7,issue 1,e30240.
8. Hung-Jen Tang, Yin-Ching Chung, Wen-Chien Kp, Chi-Chung Chen, Jiunn-Min
Shieh, Chung-Hua Chen, Nan-Yao Lee, Shyh-Ren Chiang. Comparative
evaluation of intratracheal colistimethate sodium, imipenem, and meropenem in
BALB/c mice with carbapenem-resistant Acinetobacter baumannii pneumonia.
Int J Infect Dis, 2012; 1,16(1):e34-e40.
9. Jiunn-Min Shieh, Tsan-Hwang Cheng, Ming-Der Shi, Pei-Fen WU, Yi Chen,
Shian-Chin Ko, Yuan-Wei Shih. α-Tomatine Suppresses Invasion and Migration
of Human Non-Small Cell Lung Cancer NCI-H460 Cells Through Inactivation
FAK/PI3K/Akt Signaling Pathway and Reducing Binding Activity of NF-κB. Cell
Biochem Biophys, 2011; 60,297-310.
10. Nai-Ding Liao, Jiunn-Min Shieh, Wen-Ying Lee.Diagnostic Value of
Metabolic Phenotypes in Malignant Pleural Effusions: expression of GLUT1
and CAIX by immunocytochemistry. Cancer Cytotopatho 2011,published
online (I.F:2.77, ranking 21/76=28% on pathology)
11. Jiunn-Min Shieh, Tur-Fu Hung, Chi-Feng Hung, Kuan-Hsien Chou, Yih-Jeng
Tsai and Wen-Bin Wu. Activation of c-Jun N-terminal kinase is essential for
mitochondrial membrane potential change and apoptosis induced by
doxycycline in melanoma cells. British Journal of Pharacology, 2010;
160:1171-1181.
12. Cheng-Ta Yang, Jen-Yu Hung,Chun-Liang lai, Hsin-Chia Hung, Yung-Fa Lai,
Meng-Chih Lin, Jiunn-Min Shieh, Ming-Shyan Huang. Gefitinib as First- Line
Therapy for Advanced or Metastatic NSCLC Patients in Southern Taiwan.
Kaohsiung J Med Sci. 2010, 26:1-7.
13. Pin-Liang Chen, *Jiunn-Min Shieh, Shiann-Chin Ko. Two Synchronous Primary
Lung Cancers: A case Report. Thorac Med 2010; 25: 85-90.
14. Jiunn-Min Shieh, Hung-Tsung Wu, Kai-Chun Cheng, Juei-Tang Cheng.
Melatonin ameliorates high fat diet-induced diabetes and stimulates glycogen
synthesis via a PKCζ-Akt-GSK3β pathway in hepatic cells. J. Pineal Res. 2009;
47:339-344.
15. Jiunn-Min Shieh, Tai-An Chiang, Wen-Teng Chang, Chang-Hung Chao,
Yi-Chieh Lee, Guan-YuHung, You-Xin Shih, Yuan-Wei Shih. Plumbagin
inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding
activitis of NF-κB and AP-1 via ERK signaling pathway in A549 human lung
cancer cells. Mol Cell Biochem. 2009; 335,181-193.
16. Yuan-Wei Shih, Jiunn-Min Shieh, Pei-FenWu, Yi-Chieh Lee, Yi-Zhi Chen,
Tai-An Chiang.α-Tomatine inactivates PI3K/Akt and ERK signaling pathways
in human lung adenocarcinoma A549 cells: Effect on metastasis. Food and
Chemical Toxicology. 47(2009) 1985-1995.(sci)
17. Ching-Yih Lin, Shih-Bin Su, Chih-Ching Chang, Tsung-Ming Lee, Jiunn-Min
Shieh, How-Ran Guo. The Association Between Chlamydia Pneumoniae and
Metabolic Syndrome in Taiwanese Adults. Southern Medical Journal.2009;
102(12)
18. Chi-Feng Hung, Tur-Fu Huang, Bing-Huei Chen, Jiunn-Min Shieh, Pi-Hui Wu
and Wen-Bin Wu. Lycopene Inhibits TNF-alfa-induced endothelial ICAM-1
expression and monocyte-endothelial adhesion. European Journal of
Pharmacology :volume 586, issues 1-3, 31 May 2008, P275-282.
19. Hsin-Kai Huang, Chih-Hsiung Chen, Shian-Chih Ko, Kuo-Chen Cheng,
Jiunn-Min Shieh, Kuo-Hwa Chaing. Anterior Mediastinal Type B3 Invasive
Thymoma with Multiple Intrapulmonary Metastasses: A Case Report. Thorax
Med 2008; 23: 355-361.
20. Chih-Hsiung Chen, Kun-Ming Chung, Jiunn-Min Shieh, Shian-Chin
Ko,Hsiu-Nien Shen Kuo-Chen Cheng. Hemophagocytic Syndrome Associated
with Diffuse Large-B-Cell Lymphoma: A case Report. Thorac Med 2008; 23:
55-60.
21. Su, Cheng-Chuan, Shieh Jiunn-Min, Li-Chien-Feng.Endobronchial metastatic
breast carcinoma clinically, histologically, histologically and cytologically
mimicking pulmonary small cell carcinoma. Pathology: volume 39, Number 2,
April 2007, PP. 269-271 (3).
22. Shian-Chin Ko, Jian-Fong Li, Jiunn-Min Shieh. Mycobacterium avium
complex(MAC) Lung Abscess Successful Treated with Traditional
Antituberculosis Therapy. Thorac Med 2007; 22( 6 suppl): 87.
23. Shian-Chin Ko, Yu-Feng Tian, Jiunn-Min Shieh. Drug Interaction between
Rifampin and Cycloosporin in a Renal Transplant Recipient with Pulmonary
Tuberculosis. Thorac Med 2007; 22( 6 suppl): 86.
24. Chih-Hsiung Chen, Kuo-Hwa Chiang, Shian-Chin Ko, Shyh-Ren Chiang,
Kuo-Chen Cheng, Jiunn-Min Shieh. Anterior Mediastinal Type B3 Invasive
Thymoma with Multiple Intrapulmonary Metastases. Thorac Med 2007; 22( 6
suppl): 71
25. Chih-Hsiung Chen, Tzu-Chieh Weng, Lien-Hui Hsu, Wei-Neng Lin Shyh-Ren
Chiang, Jiunn-Min Shieh. Acute Pulmonary Embolism and Occult lUng
Adenocarcinoma : A Case Report of Trousseau’s Syndrome. Thorax Med 2007;
22:243-248.
26. Chih-Hsiung Chen, Jiunn-Min Shieh, Lien-Hui Hsu, Hsiu-Nien Shen Kuo-Chen
Cheng, Shian-Chih Ko. Acute Respiratory Distress Syndrome Causes by
Mycoplasma Pneumonia Infection: A case Report. Thorax Med 2007;
22:215-221.
27. Wei-Neng Lin, Shian-Chin Ko, Chih-Hsiung, His-Hsing Yanf, Kuo-Chen Cheng,
*Jiunn-Min Shieh. Acute Pulmonary Edema Following Transjugular
Intrahepatic Portosystemic Stent Shunt Creation in A Cirrhotic Patient: A Case
Report. Thorac Med 2007; 22:259-264. (Corresponding author)
28. Shian-Chin Ko, Mei-Chun Chou, Jiunn-Min Shieh. Acute Lung Injury Induced
by Illegal Use of Ketamine Inhalation. Thorac Med 2006; 21( 6 suppl):152.
29. Shian-Chin Ko, Mei-Chun Chou, Jiunn-Min Shieh. Acute Lung Injury Induced
by Illegal Use of Ketamine Inhalation. Thorac Med 2006; 21( 6 suppl):152
30. Shian-Chin Ko, Mei-Chun Chou, Jiunn-Min Shieh. Interlobar Pulmonary
Sequestration in an Elderly Woman Incidentally Found by Three-Dimensional
Multi-dectector Computerized Tomography ( 3D MDCT) Angiography.
Thorac Med 2006; 21( 6 suppl): 151
31. Chih-Hsiung Chen, Lien-Hui Hsu,Shian-Chin Ko, Wei-Neng Lin,
Jiunn-Min Shieh. Pleural-Based Pulmonary Arteriovenous Malformation:
High Risk for Ultrasound-Guided Needle Biopsy. Thorac Med 2006; 21( 6
suppl): 104
32. Shian-Chin Ko, Jiunn-Min Shieh. A Rare Case of Ethambutol-induced Toxic
Epidermal Necrolysis ( TEN) in a Patient with Open Tuberculosis and Diabetic
Neuropathy. Thorac Med 2006; 21( 6 suppl): 163
33. Chih-Hsiung Chen, Jiunn-Min Shieh. Lien-Hui Hsu, Kuo-Chen Cheng,
Shian-Chin Ko, Acute Respiratory Distress Syndrome Associated with
Mycoplasma Pneumoniae Infection: ACase Report. Thorac Med 2006; 21( 6
suppl): 164
34. Gang-Yu Shen, Kuo-Hwa Chiang, Yao Fong, Jiunn-Min Shieh. Symptomatic
Mediastinal Bronchogenic Cyst Mimicking Esophageal lesion in a Patient with
Chronic cough-A case Report and Literature Review. Thorac Med 2006; 21:
362-368.
35. Ming-Tai Wu, Wen-Liang Yu, Jiunn-Min Shieh, Kuo Chen Cheng. Isolated
Cryptococcal Pleural Involvement in a Patient With Renal Tuberculosis.
Thorac Med 2006; 21: 208-285
36. Jiunn-Min Shieh, Kue-Lin, Zenth, Sia-Lin Din, et al. The Five Years’
Experences of Respiratory Care Center in Southern Taiwan. Thorac Med 2005;
20( 6 suppl): 79
37. Kuo-Hwa Chiang, Gang-Yu Shen, Yao Fong, Jiunn-Min Shieh. Mediastinal
Bronchogenic Cyst Presenting as Esophageal Lesion-A Case Report and Review
of the literature. Thorac Med 2005; 20( 6 suppl): 109
38. Lien-Hui Hsu, Shian-ChinKo, Kau-Chen Cheng,Yao Fong, Jinn-Ming Chang,
Ching-Nan Lin, Jiunn-Min, Shieh. Coexistence of Carcinoid Tumor and
Adenocarcinoma within the Esophageal Diverticulum Complicated with
Empyema
Thoracis—A case report. Thorac
Med
2005;
20:
463-470.(Corresponding author )
39. En-Chung Cheng, Yao-Fong, Kuo-Chen Cheng, Shih-Sung Chung, Jiunn-Min
Shieh. A Rare Case of Malignant Gastrointestinal Stromal Tumor of the
Esophagus in a Patient with Chronic Cough. Thorac Med 2005; 20: 306-312.
(Corresponding author)
40. Chin-Ming Chen, Mei-Yi Sung, Kuo-Chen Cheng , Jiunn-Min Shieh. The
Relationship between Body Mass Index and Prognosis in a Respiratory Care
Center. J Emerg Crit Care Med. Vol.16, No.1, 2005; 9-17. (Corresponding
author)
41. Sheng-Chin Liao,Yung-Chih Cheng,Yo-Ching Wang, Chiung-Wen Wang,
San-Ming Yang, Chun-Keung Yu, Chi-Chang Shieh, Kuo-Chen Cheng,
Meng-Feng Lee, Shyh-Ren Chiang, Jiunn-Min Shieh, and Ming-Shi Chang .
IL-19 Induced Th2 Cytokines and Was Up-regulated in Asthma patients.
The Journal of Immunology, 2004, 173:6712-6718(sci)
42. Yi-Chieh Yang, Yen-An Tang, Jiunn-Min Shieh, Ruo-Kai Lin, Han-Shui Hsu,
Yi-Ching Wang. DNMT3B Overexpression by deregulation of
FOXO3a-Mediated Transcription Repression and MDM2 Overexpression in
Lung Cancer. J Thorac Oncol. 2014;9: 1305-1315.(Co- first authors)
43. Jen-Yu Hung, Shyh-Ren Chiang, Ming-Ju Tsai, Ying-Ming Tsai, Inn-Wen
Chong, Jiunn-Min Shieh, Ya-Ling Hsu. LIGHT is a Crucial Mediator of
Airway Remodeling. J.Cell. Physiol. 2015 May;230(5):1042-53.
44. Jiunn-Min Shieh, Chih-Jie Shen, Wei-Chiao Chang, Hung-Chi Cheng, Ya-Yi
Chan, Wan-Chen Huang, Wen-Chang Chang, Ben-Kuen Chen. An Increase in
Reactive Oxygen Species by Deregulation of ARNT Enhances
Chemotherapeutic Drug-Induced Cancer Cell Death. PLOS one, 2014;9(6):
e99242.
45. Jiunn-Min Shieh, Yih-Jeng Tsai, Chih-Jen Tsou, Wen-Bin Wu.CXCL1
Regulation in Human Pulmonary Epithelial Cells by Tumor Necrosis Factor.
Cell Physiol. Biochem. 2014;34:1373-1384.
46. Jiunn-Min Shieh, Yen-An Tang, Tsung-Han Yang, Chih-Yi Chen, Han-Shui
Hsu, Yi-Hung Carol Tan, Ravi Salgia, Yi-Ching Wang. Lack of Association of
C-Met-N375S Sequence Variant with Lung Cancer Susceptibility and Prognosis.
Int.J.Med.Sci.2013; 10(8):988-994.
47. S-C. Hsing, S-F. Weng, K-C. Cheng, J-M. Shieh, C-H. Chen, S-R. Chiang, J-J.
Wang. Increased risk of pulmonary tuberculosis in patients with previous
non-tuberculous mycobacterial disease. Int. J. Tuberc. Lung Dis.
2013,17(7):928-933.
48. Jia-Yang Chen, Yen-An Tang, Wen-Shan Li, Yu-Ching Chiou, Jiunn-Min
Shieh*, Yi-Ching Wang*. A Synthetic Podopyllotoxin Devirative
ExertsAnt-Cancer Effects by Inducing Mitotic Arrest and Pro-Apoptotic ER
Stress inLung Cancer Preclinical Models. PLoS one, 2013, April: e62082.
(Corresponding author)
49. Shian-Chih Ko*, Chi-Ruei Huang*, Jiunn-Min Shieh, Jhen-Hong Yang,
Wen-Chang Chang, Ben-Kuen Chen. Epidermal Growth Factor Protects
Squamous Cell Carcinoma against Cisplatin-Induced Cytotoxicity through
Increased Interleukin-1β Expression. PLOS one, 2013,8(2): e55795
50. Jiunn-Min Shieh, Yung-Chan Chen, Yin-Chao Lin, Jia-Ni Lin, Wei-Chih
Chen,Yang-Yuan Chen, Chi-Tang Ho, Tzong-Der Way. Demethoxycurcumin
Inhibits Energy Metabolic and Oncogenic Signaling Pathways through AMPK
Activation in Triple-Negative Breast Cancer Cells. J.Agric.Food Chem.2013, 61,
6366-6375.
51. Huey-Ming Lo, Jiunn-Min Shieh, Chih-Li Chen, Chih-Jen Tsou, Wen-Bin Wu.
Vascular Endothelial Growth Factor Induces CXCL1 Chemokine Release via
JNK and PI-3K-Dependent Pathways in Human Lung Carcinoma Epithelial
Cells. Int.J. Mol.Sci.2013,14, 10090-10106.
52. Jiunn-Min Shieh, T.-T. Wei, Y.-A. Tang, S.-M. Huang, W.-L. Wen, M.-Y. Chen,
S.B. Salunke, C.-T. Chen, C.-S. Chen, Y-C Wang. Mitochondrial apoptosis and
FAK signaling disruption by a novel histone deacetylase inhibitor, HTPB, in
antitumor and antimetastatic mouse models. PLoS one, 2011,7(1): e30240.
53. Hung-Jen Tang, Yin-Ching Chung, Wen-Chien Kp, Chi-Chung Chen,
Jiunn-Min Shieh, Chung-Hua Chen, Nan-Yao Lee, Shyh-Ren Chiang.
Comparative evaluation of intratracheal colistimethate sodium, imipenem, and
meropenem in BALB/c mice with carbapenem-resistant Acinetobacter
baumannii pneumonia. Int J Infect Dis, 2012; 1,16(1):e34-e40.
54. Jiunn-Min Shieh, Tsan-Hwang Cheng, Ming-Der Shi, Pei-Fen WU, Yi Chen,
Shian-Chin Ko, Yuan-Wei Shih. α-Tomatine Suppresses Invasion and Migration
of Human Non-Small Cell Lung Cancer NCI-H460 Cells Through Inactivation
FAK/PI3K/Akt Signaling Pathway and Reducing Binding Activity of NF-κB. Cell
Biochem Biophys, 2011; 60,297-310.
55. Nai-Ding Liao, Jiunn-Min Shieh, Wen-Ying Lee.Diagnostic Value of
Metabolic Phenotypes in Malignant Pleural Effusions: expression of GLUT1
and CAIX by immunocytochemistry. Cancer Cytotopatho 2011,published online
(I.F:2.77, ranking 21/76=28% on pathology)
56. Jiunn-Min Shieh, Tur-Fu Hung, Chi-Feng Hung, Kuan-Hsien Chou, Yih-Jeng
Tsai and Wen-Bin Wu. Activation of c-Jun N-terminal kinase is essential for
mitochondrial membrane potential change and apoptosis induced by
doxycycline in melanoma cells. British Journal of Pharacology, 2010;
160:1171-1181.
57. Pin-Liang Chen, *Jiunn-Min Shieh, Shiann-Chin Ko. Two Synchronous Primary
Lung Cancers: A case Report. Thorac Med 2010; 25: 85-90.
58. Jiunn-Min Shieh, Hung-Tsung Wu, Kai-Chun Cheng, Juei-Tang Cheng.
Melatonin ameliorates high fat diet-induced diabetes and stimulates glycogen
synthesis via a PKCζ-Akt-GSK3β pathway in hepatic cells. J. Pineal Res. 2009;
47:339-344.(sci)
59. Jiunn-Min Shieh, Tai-An Chiang, Wen-Teng Chang, Chang-Hung Chao,
Yi-Chieh Lee, Guan-YuHung, You-Xin Shih, Yuan-Wei Shih. Plumbagin
inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding
activitis of NF-κB and AP-1 via ERK signaling pathway in A549 human lung
cancer cells. Mol Cell Biochem. 2009; 335,181-193.(sci)
60. Yuan-Wei Shih, Jiunn-Min Shieh, Pei-FenWu, Yi-Chieh Lee, Yi-Zhi Chen,
Tai-An Chiang.α-Tomatine inactivates PI3K/Akt and ERK signaling pathways
in human lung adenocarcinoma A549 cells: Effect on metastasis. Food and
Chemical Toxicology. 47(2009) 1985-1995.(sci)
61. Ching-Yih Lin, Shih-Bin Su, Chih-Ching Chang, Tsung-Ming Lee, Jiunn-Min
Shieh, How-Ran Guo. The Association Between Chlamydia Pneumoniae and
Metabolic Syndrome in Taiwanese Adults. Southern Medical Journal.2009;
102(12)
62. Cheng-Ta Yang, Jen-Yu Hung,Chun-Liang lai, Hsin-Chia Hung, Yung-Fa Lai,
Meng-Chih Lin,
Jiunn-Min Shieh, Ming-Shyan Huang. Gefitinib as
First- Line Therapy for Advanced or Metastatic NSCLC Patients in Southern
Taiwan. Kaohsiung J Med Sci. 2010, 26:1-7.
63. Chi-Feng Hung, Tur-Fu Huang, Bing-Huei Chen, Jiunn-Min Shieh, Pi-Hui Wu
and Wen-Bin Wu. Lycopene Inhibits TNF-alfa-induced endothelial ICAM-1
expression and monocyte-endothelial adhesion. European Journal of
Pharmacology:volume 586, issues 1-3, 31 May 2008, P275-282.
64. Hsin-Kai Huang, Chih-Hsiung Chen, Shian-Chih Ko, Kuo-Chen Cheng,
Jiunn-Min Shieh, Kuo-Hwa Chaing. Anterior Mediastinal Type B3 Invasive
Thymoma with Multiple Intrapulmonary Metastasses: A Case Report. Thorax
Med 2008; 23: 355-361.
65. Chih-Hsiung Chen, Kun-Ming Chung, Jiunn-Min Shieh, Shian-Chin
Ko,Hsiu-Nien Shen Kuo-Chen Cheng. Hemophagocytic Syndrome Associated
with Diffuse Large-B-Cell Lymphoma: A case Report. Thorac Med 2008; 23:
55-60.
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