Semester 2 Biology Study Guide MEIOSIS (Chapter 9.5-9.6) 1. What is the difference between haploid and diploid? What do they have to do with meiosis? Haploid – cells with half the amount of chromosomes (sperm & egg) Diploid – full set of chromosomes Meiosis makes haploid cells 2. What is crossing over and why is it important? Homologous chromosomes exchanging pieces of DNA It acts as a source of variation within a species 3. When are homologous chromosomes paired up? in meiosis 4. What is the goal of meiosis? to form haploid cells (sperm and egg) DNA & PROTEIN SYNTHESIS (Chapter 11) 5. Draw a picture of DNA labeling the nitrogen bases, phosphate group, and the deoxyribose. A T C G T A A T G C 6. When does DNA replication happen and what is the goal of it? Copying of DNA so each new daughter cell has the same # of chromosomes as the parent cells 7. Identify and describe the steps of Protein Synthesis. 1. DNA is converted into mRNA 2. mRNA goes from the nucleus to the cytoplasm 3. mRNA attaches to a ribosome 4. tRNA attaches to the mRNA 5. amino acids attached to the tRNA are lined up to create a protein 8. If the original strand of DNA is AATTGGCC what will be the sequence of the complementary strand of DNA? TTAACCGG 9. What are amino acids? amino acids are the building blocks of proteins 10. What are genes? genes carry the code for making proteins 11. The mRNA is AUCGCA. What is the DNA? What are the amino acids (use the table provided)? TAGCGT Iso, Ala 12. What is a mutation? Change in the DNA FIRST BASE Base substitution will affect only one amino acid. Base deletion or insertion will change all the following amino acids C A 14. Explain why a mutation can have no G effect. Helpful – increased diversity Harmful – causes defects Neutral – doesn’t change the amino acid G Cys Cys Stop Trp Arg Arg Arg Arg Ser Ser Arg Arg Gly Gly Gly Gly U C A G U C A G U C A G U C A G THIRD BASE 13. Why would an insertion or deletion mutation have more of an effect than a substitution mutation? U U Phe Phe Leu Leu Leu Leu Leu Leu Iso Iso Iso Met Val Val Val Val SECOND BASE C A Ser Tyr Ser Tyr Ser Stop Ser Stop Pro His Pro His Pro Gln Pro Gln Thr Asn Thr Asn Thr Lys Thr Lys Ala Asp Ala Asp Ala Glu Ala Glu 15. What is a mutagen and give 2 examples? Something that causes a mutation…Examples: smoking and tanning GENETICS (Chapters 10, 12, 13) 16. Differentiate between phenotype and genotype. Phenotype – characteristics that you can see Genotype – the letters 17. In humans freckles is a dominant trait. Cross a heterozygous mom with a dad that does not have freckles. List the phenotypes and genotypes of the offspring. F f Ff x ff Phenotype Genotype f Ff ff mom dad 50% Freckles 50% Ff f Ff ff 50% no freckles 50% ff 18. What are the sex chromosomes of male and females? Males – XY Females – XX Male determines a child’s sex because he has both X and Y 19. Give an example or explain the following: intermediate inheritance (incomplete dominance), polygenic traits, test cross, and codominance. incomplete dominance – blending of traits RR-red Rr- pink rr-white polygenic traits – many genes affect one trait (Example: eye color) test cross – crossing 2 organisms so you figure out their genotypes codominance – both traits show up RR- red Rr red & white rr - white 20. Complete a Punnett Square for the following cross. AaBb X AaBb 21. Is it possible to have a child with blood type O if the mom has blood type A and dad has blood type B? Show your work. IB i IA i I AI B IBi IAi ii I Ai x mom IBi dad Yes! 25% chance AB Ab aB ab AB AABB AABb AaBB AaBb Ab AABb AAbb AaBb Aabb aB AaBB AaBb aaBB aaBb ab AaBb Aabb aaBb aabb 22. Hemophilia is a recessive sex-linked trait. Cross a normal father with a mother who is a carrier for hemophilia. Is it possible for them to have a child with hemophilia? Show your work. XH Y XH XHXH XHY Xh XHXh XhY XHXh mom x XHY dad Yes! 25 % chance that they will have a boy who has hemophiia 23. Differentiate between heterozygous and homozygous. heterozygous – having a dominant gene and a recessive gene for a trait Rr homozygous – having two of the same gene for a trait RR or rr 24. Describe the process of cloning animals. Take the DNA out of the body cell from one animal. Take the DNA from the egg cell from another animal. Put the DNA from the body cell into the egg cell and place the cell into a foster mom. 25. What are 2 applications for DNA fingerprinting? Paternity tests Crime scenes DNA is unlikely to be the same in different people 26. What is recombinant DNA and how is it produced? Recombinant DNA is DNA from 2 different organisms joined together 27. Explain what a genetically modified organism (GMO) is and give 2 examples. Any example of animal getting a gene from some other organism, so that it can use the gene’s instructions to produce the protein that the animal would not normally produce. Example glowing animals. TAXONOMY (Chapter 15.4) 28. Using binomial nomenclature the scientific name for a dog is Canis familiaris What is the genus name? Canis 29. List and describe the characteristics of each kingdom. Animalia – multicellular, no cell walls, no chloroplasts Plantae – multicellular, cells walls, chloroplasts Fungi – multicellular, cell walls, no chloroplasts Protista – single celled organism with a nucleus, chloroplasts, no cell walls Monera – single celled organism without a nucleus EVOLUTION (Chapters 14-15) 30. What is evolution? a change over time, variation (such as mutation) must exist for evolution to occur 31. Describe the difference between macroevolution and microevolution. Give examples of each. macroevolution – formation of an entirely new species from an existing species (Example: ape to man) takes a long time!!! microevolution – changes that occur within a species over time (Example: bacteria becoming immune to antibiotics) 32. Define and give an example of natural selection. Organisms that are better suited to their environment are more likely to survive and reproduce. Natural selection results in a change in gene frequency. Example: bacteria becoming immune to antibiotics 33. List and describe the evidence used for evolution. Fossils – oldest evidence Examples: imprints of leaves, footprints, and skeletons Vestigial structures – structure that an organism has but does not use Example: whale pelvis Homologous Structures – similarities in bone structures that show a common ancestor DNA – newest evidence ANATOMY (Chapters 27-33) 34. Describe the functions of the following systems: integumentary, skeletal, muscular, circulatory, respiratory, nervous, digestive, immune, endocrine, reproductive, and excretory. integumentary – body covering skeletal – protection, support, & makes red blood cells muscular – movement circulatory – delivery of materials respiratory – gas exchange nervous – controls by electrical signals digestive – breakdown of food immune – fights disease endocrine – controls body through hormones reproductive – produces offspring excretory – eliminates waste 35. Draw a picture of 2 neurons. Label and explain the functions of the myelin sheath, axon, dendrites, synapse, receptors, and nucleus myelin sheath – insulates axon – sends message dendrites – receive message synapse – space between neurons receptors – place where message hits nucleus – controls activities 36. What is Multiple Sclerosis (MS)? The immune system attacks the myelin sheath 37. Draw a graph showing the primary and secondary immune response. 38. How does a vaccine protect you from getting the disease? Forces your body to create memory B cells 39. How is HIV transmitted? unprotected sex and through the blood 40. Define the following: autoimmune disease, allergy, and antihistamine. autoimmune disease – body attacks itself allergy – abnormal response to a harmless antigen antihistamine – drug that blocks the histamine reaction 41. What is the function of arteries, veins, and capillaries? arteries – carry blood away from heart veins – carry blood to the heart capillaries – small vessels in between arteries and veins (allow for gas exchange) 42. What is cardiovascular disease and how can it be prevented? Coronary arteries are blocked Don’t smoke, Don’t eat foods high in fat & cholesterol 43. How does your body know when to take a breath? High concentration of Carbon Dioxide in the blood 44. Where do the circulatory and respiratory systems connect? capillaries and the alveoli 45. What is ovulation and when does it occur? ovulation is when pregnancy is most likely to happen it occurs about 2 weeks into the menstrual cycle 46. Where does fertilization usually occur? in the fallopian tube 47. How do the nutrients move from the mother to the fetus? through the placenta 48. Describe the path that food travels through the digestive system. mouth, esophagus, stomach, small intestine, large intestine, out! 49. What is the function of the following digestive organs: liver, small intestine, stomach, and esophagus? liver – removes glucose from the blood & stores it as glycogen for later use small intestine – absorption stomach – holding area for food esophagus – moves food from mouth to stomach 50. What characteristics of the digestive system allow for more absorption? villi in the small intestine 51. Explain how drugs affect the nervous system. they hit the receptors in the synapse and wear out the receptors