BIODATA OF DR. MAUSUMI BHARADWAJ Name in Full Mausumi Bharadwaj (nee Sinha Roy), Ph D Present Designation Assistant Director & Chief, Div.of Molecular Genetics & Biochemistryx Address Institute of Cytology & Preventive Oncology, (Indian Council of Medical Research), I-7, Sector – 39, Post Box No. 544, Noida – 201 301 Tel.No.: (95120) –2579471 / 72 Extn. 229/228 Telefax: (95120) - 2579473 Old Campus Maulana Azad Medical College Campus, New Delhi-110002 Tel.No.: 23221596 Fax 91-11-23233406 E-mail: bharadwajm@icmr.org.in mausumi02@yahoo.com Date and place of Birth 9th January 1963; Kolkata, West Bengal Nationality Indian Residential Address Flat No.763, F-8, Sagar Presidency Sector 50, Noida 201301 Positions held earlier (in chronological order): 1988-1990 Junior Research Fellow, NET qualified for Council of Scientific and Industrial Research (CSIR) in Indian Institute of Chemical Biology, Kolkata, India. Molecular and Biochemical characterization of novel proteases from mitochondria of rat submaxillary gland using various biochemical techniques specially using HPLC, western blot analysis, isoelectric focusing etc. 1990-92 Senior Research Fellow, sponsored by Council of Scientific and Industrial Research (CSIR) in Indian Institute of Chemical Biology, Kolkata, India Molecular characterization of the protease through cloning and expression. 1992-93 Post-Doctoral Research Fellow in the Department of Microbiology & Immunology, University of Health Sciences/The Chicago Medical School, North Chicago, Illinois, USA Molecular and immunological characterization of some novel anti-fertility proteins from human reproductive tract using HPLC, FPLC, Eliza, Cytotoxic T Lymphocye assay etc. 1993-95 Research Associate Staff I in the Department of Biochemistry, University of New Mexico, School of Medicine, Albuquerque, NM 87131, USA Characterization of protein palmitoylation of Protein Po of Central nervous system through synthetic peptide library through series of peptide synthesis and characterization by GC-Mass spectro analysis. 1995-1999 Research Associate Staff I in the Department of Pathology, University of New Mexico, School of Medicine, Albuquerque, NM 87131, USA Sin nombre Hantavirus variant analysis through sequencing of G1, G2 genes of viral coat protein as well as nucleocapsid protein gene N1, Development of experimental infection model of Sin nombre Hantavirus in deer mouse, Development of DNA vaccine against Sin nombre Hantavirus in deer mouse as well as in balb/c mouse and evaluation of immunogenic efficacy through virus neutralization assay, Eliza, T-cell proliferation etc. 1999-2000 Research Assistant Professor in the Department of Pathology, University of New Mexico, School of Medicine, Albuquerque, NM 87131, USA Development of Degue virus DNA vaccine through gene shuffling technology . 2001-2003 Senior Scientist, GenoMed (IGIB-NPIL knowledge alliance), Institute of Genomics & Integrative Biology (CSIR) , Delhi University Campus, Mall Road, Delhi-110007. 2 Handled four different genomics projects : Diabetes, Asthma, Schizophrenia, Pharmacogenomics. Looked for novel Single Nucleotide Polymorphisms (SNPs) through sequencing as genetic marker. 2003-present Assistant Director & Chief Department of Molecualr Genetics & Biochemistry, Institute of Cytology & Preventive Oncology (ICMR), sector 39, Noida. Handling project to develop DNA vaccine against HPV 16 variant, Genetics & Proteomics of Cervical cancer in Indian population and Predictive medicine using single nucleotide polymorphisms. Academic Qualifications: DEGREE UNIVERSITY / PLACE YEAR B.Sc. (Hons) Chemistry University of Calcutta 1984 M.Sc. Biochemistry University of Calcutta 1986 Ph.D. (Science) Jadavpur University 1993 Ph.D. Title : Studies on mitochondrial membrane-bound protease in submaxillary gland. Field of Specialization MOLECULAR VIROLOGY & VACCINES, GENETICS OF CANCER Academic award / Honors Obtained: Travel award from the 45th Annual Meeting of the American Society of Tropical Medicine and Hygiene held in Baltimore, Maryland, December 1-5, 1996 Invited Talks DNA VACCINES-Past, Present & Future. In“Advance Seminar Series” organized by Dept. of Biotechnology, AIIMS. Member : Indian Association for Cancer Research 3 : Society of Biological Chemists Professional, Assignments Ad hoc Reviewer of the Journal “Indian J Biochem Biophysics” External Examiner for B.Sc.(H) Biotech, Amity Institute of Biotechnology 8 th June, 2006. Adjunct Faculty of Department of Biochemistry, University of Delhi, South Campus, New Delhi. 1. 2. 3. Handling Project Principle Investigator / Co-Investigator Principle Investigator 1. Development of Prophylactic DNA-based Vaccine Against Human Papillomavirus type 16 and 18 2. Polymorphism of Cytokine Gene Tumor Necrosis Factor (TNF ) in Cervical Cancer 3. Cyclin D1 Gene Polymorphism in Cervical Precancer and Cancer 4. Single Nucleotide Polymorphisms of Cytokine Genes in Human Papillomavirus (HPV)-mediated Cervical Cancer in Women funded by CSIR. Co-Investigator 1. Role of Tobacco use in causation of cancer in North East India - ICMR task force project. 2. Role of Pesticide Exposure in causation of cancer in North East India - ICMR task force project 3. Prevalence and Persistence of HPV infection during and after pregnancy and its transmission to child (Sumitter to ICMR) 4. Prevalence of HPV infection and MTHFR gene polymorphism in peri and post menopausal women Ph.D.Students Registered as Supervisior / Co-Supervisors 1. Indu Kohaar “ Role of Cytokines in the development of Cervical Cancer” – registered in Dept of Biochemistry, South Campus, Delhi University. 2. Md.Kausar Neyaz “ Mutationl and Expression Studies of FHIT gene in Cervical Cancer cases”- registered in Dept of Biosciences, Jamia Millia Ismalia University. 4 M.D.Student Sashideep Singhal, Department of Surgery, Maulana Azad Medical college, 2006 M.SC. project Dissertations carried out. (For 6 Months) 1. Sandeep Kumar Mishra “Methylation Pattern of FHIT gene in Cervical Cancer”. Dept of Biotechnology, Bundelkhand University, Jhansi, 2004. 2. Anu Tripathi, “ Methylation Pattern of RASSFIA gene in Cervical Cancer”. Dept of Biotechnology, Bundelkhand University, Jhansi, 2004. 3. Ankur Saikia “Methylation Pattern of RASSFIA gene from DNA of Peripheral Blood Lymphocytes”.Dept of Molecular Biology & Biotechnology, Tezpur University, Assam. 2005. 4. Pratibha Tiwari “Analysis of TNF Gene Promoter Polymorphisms in Healthy North Indian Population”. Dept. of Biochemistry, Devi Ahalya University, 2005. 5. Prem Kumar “ Mutational analysis of -catenin gene in Cervical Cancer”. Dept of Biotechnology, Bundelkhand University, Jhansi, 2005. 6. Megha Bharti Saxena, Analysis of SNPs in TNFa gene promoter in healthy North Indian (Delhi) population, Dept of Microbiology, Barkhatulla University , Bhopal, 2006. 7. Richa Nayak, “Analysis of Cyclin D1 gene polymorphism in healthy North Indian (Delhi) population”, Dept. of Biotechnology, Rajiv Gandhi College, Satna, M.P. (A.P.S.University, Rewa), 2006. 8. Mohammed Asad, “ Molecular cloning and expression of CRPV L1 ORF in Prokaryotic System” Dept of Biotechnology, Jiwaji University, Gwalior, MP. 9. Deepak Maheshwari “Cyclin D1 Gene Polymorphism in Urinary Bladder Cancer” Bachelor of Technology in Biotechnology, Seedling Academy of Design, Technology and Management Jaipur (Rajasthan), 2006. 10. Surendra Kumar, “MTHFR gene polymorphism in control Indian population” Dept of Biochemistry, CCS University., Meerut., 2006. Summer Training 1. Shank Sharma –B.Tech. Allahabad Agriculturer University.-2004 5 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. Ayushman Gupta - B.Tech. Allahabad Agriculturer University.-2004 Anjani Sharma- B-Tech, Biotech, CET-IILM, Greater Noida, 2005 Subhash Singh M.Sc- Biotechnology, Chaudhury Charan Singh University, Meerut 2005 Neelam Joshi, B.Tech –Biotechnology, Amity Institute of Biotechnology, Noida 2005 Vinti Bagga - M.Sc.-Zoology, Dr. B R Ambedkar University, 2005 Anshuk Sarkar (B.Sc.), Hons in Biochemistry – Deshbandhu college, Delhi University 2005 Harshana Sabharwal, 2006 Richa Sharma, Jamia Milia Islamia, 2006 Dr.Jagdeep Singh, Academy fellow, 2006 Dhiraj Kr Banerjee, B.Tech, Biotech , Amity Institute of Biotechnology, 2006 Subha Verma, B.Tech, Biotech, IILM.,2006. Prem Chand, M.Sc, Zoology (Campus), Ch.Charan Singh University, Meerut (UP), 2006 Participation in Workshop 1. 2. 3. 3rd Indo-US Workshop on “Genetic Epidemiological Methods for Dissection of Complex Human Traits” January 4th-12th, 2007 in Kolkata Indo-US workshop on “Bioethics in Clinical Research”, 20-22 June, 2006 in Hyatt Regency, New Delhi. Attained workshop on “Ethical Review for Protection of Human Participiants involved in Research”, 29th April, 2006 in New Delhi, ICMR. PUBLICATIONS 1. Indu Kohaar, Nisha Thakur, Sudha Salhan, Swaraj Batra, Veena Singh, Anita Sharma, Pushpa Sodhani, B C Das, Debi P Sarkar and Mausumi Bharadwaj. TNF –308G/A polymorphism as a risk factor for HPV associated Cervical Cancer in Indian population. Cellular Oncology, 2007 (In press). 2. Shashideep Singhal, Indu Kohaar, Mausumi Bharadwaj, Anita Chakravarty, Ranjana Gondal, Bhudev C Das and Premashis Kar. Fas and TNF Mediated Apoptosis and TNF Gene Polymorphism in Fulminant Hepatic Failure and Its Clinical Relevance. American J Gastroenterol 101 , 322, 2006. 3. Nisha Thakur, Indu Kohar, S Batra, V Singh, S Gupta, B C Das and M Bharadwaj. Involvement of Molecular Marker in Cervical Cancer Indian J Med Res , 121 (Supplement), 110, 2005. 6 4. Indu Kohaar, Nisha Thakur, Sudha Salhan, Pushpa Sodhani, Mahendra P, Alok Mishra, B C Das, Debi P Sarkar and M Bahradwaj. Polymorphism of Cytokine Gene, Tumor Necrosis Factor in Cervical Cancer. Indian J Med Res, 121 (Supplement), 106, 2005. 5. Mausumi Bharadwaj, Katy Mirowsky, Jason Botten, Barbara Masten, Joyce Yee, Brian HjelleGenetic vaccines that protect against Sin Nombre virus challenge in the deer mouse model. J. Gen.Virology, 83, 1745-1751, 2002. 6. Mausumi Bharadwaj, Robert Nofchissey, Diane Goade, Frederick Koster and Brian Hjelle. Humoral immune responses in the hantavirus cardio-pulmonary syndrome. Journal of Infectious Disease 182: 43-48, 2000. 7. Jason Botten, Katy Mirowsky, Donna Kusewitt, Mausumi Bharadwaj, Richard Feddersen, Roy Ricci, and Brian Hjelle. Animal model for Sin Nombre hantavirus infection in the deer mice (Peromyscus maniculatus) using a novel outdoor biocontainment facility: early viral invasion of heart and brown fat. Proc. Natl. Acad. Sci. USA. 97:10578-10583, 2000. 8. Reetesh K Pai, Mausumi Bharadwaj, Howard Levy, Gary Overturf, D Goade, Ivo A Wortman, Robert Nofchissey and Brian Hjelle. Absence of Infection of a Neonate after Probable Exposure to Sin Nombre Hantavirus in breast milk. Clinical Infectious Diseases 29: 1577-1579, 1999. 9. Mausumi Bharadwaj, C.R. Lyons, B. Wortman, B.Hjelle. Intramuscular inoculation of Sin Nombre virus cDNAs induces cellular and humoral immune responses in BALB/c mice. Vaccine 17: 2836-2843, 1999. 10. Brian Hjelle, Norah Torrez-Martinez, Mausumi Bharadwaj. (1999). Recombinant western blot and strip immunoblot assays for hantaviruses. Manual of Hemorrhagic Fever with Renal Syndrome and Hantavirus Syndrome, 122130. Edited by Ho Wang Lee, Charles Calisier and Connie Schmaljohn. 11. Norah Torrez-Martinez, Mausumi Bharadwaj, Diane Goade, John Delury, Peggy Moran, Bradley Hicks, Beverlee Nix, James L. Davis, Brian Hjelle. Bayou virus associated hantavirus pulmonary syndrome in eastern Texas: Identification of the rice rat Oryzomys palustris as the reservoir host. Emerging Infectious Dis. 4:105-111, 1998. 12. J.F. Ferrer, C. Johnson, E. Esteban, D. Galligan, M.A. Basombrio, M. PeraltaRamos, M. Bharadwaj, Norah Torrez-Martinez, J. Callahan, A. Segovia, Brian HjelleHigh prevalence of hantavirus infection in Indian communities of the 7 Paraguayan and Argentinean Gran Chaco.Amer. J. Trop. Med. Hyg. 59: 438444, 1998. 13. Mausumi Bharadwaj, Jason Botten, Norah Torrez-Martinez, Brian Hjelle. Rio Mamore hantavirus: genetic characteristics of a newly-recognized virus of the pygmy rice rat, Oligoryzomys microtis, from Bolivia. Amer. J. Trop. Med. Hyg. 57:368-374, 1997. 14. Julie A. Rawlings, Norah Torrez-Martinez, Susan U. Neil, Guy M. Moore, Bradley N. Hicks, Sergio Pichuantes, Anton Nguyen, Mausumi Bharadwaj, Brian Hjelle. Cocirculation of multiple hantaviruses in Texas, with characterization of the S genome of a previously-undescribed virus of cotton rats (Sigmodon hispidus). Amer. J. Trop. Med. Hyg. 55: 672-679, 1996. 15. Mausumi Bharadwaj, Dwaipayan Bharadwaj, and Ratha N. Hati. Characterization of a membrane protease from rat submaxillary gland mitochondria that possess thrombin-like activity. Biochem. J. 313:193-199. 1996. 16. Mausumi Bharadwaj and Oscar A. Bizzozero. Myelin Po glycoprotein and the synthetic peptide IRYCWLRR are both autoacylated. J. Neurochemistry 65: 1805-1815,1995. 17. Oscar A. Bizzozero, Sabine U. Tetzloff and Mausumi Bharadwaj. Overview: protein palmitoylation in the nervous system: current views and unsolved problems. Neurochemical Research 19:923-933, 1994. 18. Dwaipayan Bharadwaj, Mausumi Sinha Roy, Dipak Bose, and Ratha N. Hati. A new blood coagulating protease in mitochondrial membranes of rat submaxillary gland. Purification and characterization of protease and its blood coagulating activity. J. Biol. Chem. 269:16229-16235, 1994. 19. Dwaipayan Bharadwaj, Mausumi Sinha Roy, Gautam Saha, Ratha N. Hati. Pyroglutamate aminopeptidase in rat submaxillary gland. Indian J. Biochem. Biophys. 29:442-444, 1992. 20. D. Bharadwaj, A. Mukherjee, M. Sinha Roy, R.N. Hati, and R.N. Mukherjee. Silanized silica bound trypsin as analytical probe. Indian J. Biochem. Biophys. 29:375-377, 1992. 21. Mausumi Sinha Roy, Dwaipayan Bharadwaj, and Ratha N. Hati. Chymotrypsinogen: an activating enzyme in mitochondrial membrane of rat submaxillary gland. Biochemistry International 25:1035-1041, 1991. 22. Mausumi Sinha Roy, Dwaipayan Bharadwaj, and Ratha N. Hati. 8 Resolution of peripheral membrane proteases from mitochondrial pellet of rat submaxillary gland. Current Science 60:325-326, 1991. No. of Conferences / Symposia Attended: 1. Indu Kohaar, Samar H Naqvi ,Vilas Nasre, Mahendra Pratap, Nisha Thakur, B.C.Das and Mausumi Bharadwaj . Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms and Susceptibility to Cervical Cancer. Had been selected for oral presentation in 26th Annual Convention of Annual Convention of Indian Association for Cancer Research and International Symposium on Translational Research in Cancer held in January 17-19, 2007 in Bhubaneswar. 2. IACR-Delhi chapter, New Delhi, 2006 3. Ranbaxy Science Foundation, New Delhi, 2006 4. Nisha Thakur, Indu Kohar, S Batra, V Singh, S Gupta, B C Das and M Bharadwaj. Involvement of Molecular Marker in Cervical Cancer. Had been selected for presentation in 24th Annual Convention of IACR & International Symposium on HPV and Cervical Cancer held in Feb 9-12, 2005 at Noida. 5. Indu Kohaar, Nisha Thakur, Sudha Salhan, Pushpa Sodhani, Mahendra P, Alok Mishra, B C Das, Debi P Sarkar and M Bahradwaj. Polymorphism of Cytokine Gene, Tumor Necrosis Factor in Cervical Cancer. Had been selected for presentation in 24th Annual Convention of IACR & International Symposium on HPV and Cervical Cancer held in Feb 9-12, 2005. 6. M. Bharadwaj, R.Suresh Kumar and A.B Mitra. Future of SNP as Marker for Polygenic Cancers. Had been selected for presentation in International Symposium on Molecular Toxicology and Environmental Health held in Lucknow from Nov 5-8, 2003. 7. S. Wazid, S. Naqvi, M. Bharadwaj and A.B.Mitra. CYP2D6 Polymorphism and Tobacco consumption among patients with Cervical Cancer. Had been selected for presentation in International Symposium on Molecular Toxicology and Environmental Health held in Lucknow from Nov 5-8, 2003. 8. Chunyan Ye, Diane Goade, Robert Nofchissey, Mausumi Bharadwaj, Joseph Prescott, Kendall Crookston, Brian Hjelle. Promise of passive immunotherapy for Hantavirus Cardiopulmonary Syndrome(HCPS).Has been selected for presentation 21st Ann Mtg Amer Soc Virol, Lexington KY, July 20-24, 2002. 9 9. M. Bharadwaj, K. Mirowsky, J. Botten, B. Hjelle. Genetic vaccines that protect against Sin Nombre virus challenge in the deer mouse model. Had been selected for oral presentation in the 49th Annual Meeting of the American Society of Tropical Medicine and Hygiene which will going to held Westin Galleria and Oaks, Houston, Texas from Oct 29-Nov 2, 2000. 10. J. Botten, J. Yee, K. Mirowsky, M. Bharadwaj, and B. Hjelle. Taqman quantitative reverse transcriptase-PCR studies of Sin Nombre Hantavirus in the deer mouse model. Had been selected for oral presentation in the 49th Annual Meeting of the American Society of Tropical Medicine and Hygiene which will going to held Westin Galleria and Oaks, Houston, Texas from Oct 29-Nov 2, 2000. 11. M. Bharadwaj, K. Mirowsky, J. Botten, C. R. Lyons, J Yee, R. Nofchissey and B. Hjelle. Intramuscular inoculation of Sin Nombre Hantavirus cDNAs protects deer mice from challenge with Sin Nombre virus. Presented in the 19th Annual Meeting of the American Society for virology at Colorado state University, Fort Collins, Colorado, July 8-12, 2000. 12. M. Bharadwaj, R. Nofchissey, D. Goade, F. Koster and B. Hjelle. Humoral immune responses in the Hantavirus cardio-pulmonary syndrome. Had been selected for oral presentation in the keystone symposia 2000, which held at Taos, January 24-30, 2000. 13. M. Bharadwaj, C. R. Lyons, B. Wortman, B. Hjelle. (1999). Intramuscular inoculation of Sin Nombre Hantavirus cDNAs induces cellular and humoral immune responses in BALB/c mice. Selected and delivered as an oral presentation in the 18th Annual Meeting of the American Society for Virology at Univ. of Massachusetts, July 10-14, 1999. 14. J. W. Botten, H. Kirkendoll-Ahern, T. Yates, R. Ricci, M. Bharadwaj, I.A Wortman, and B. Hjelle. Selected for oral presentation in the 18th Annual Meeting of the American Society for Virology at Univ. of Massachusetts, July 10-14, 1999. 15. M.Bharadwaj, C.R. Lyons, B.Wortman, B.Hjelle. (1998 ).Genetic immunization with Sin Nombre virus cDNAs induces T cell proliferative responses and antibodies in BALB/c mice Selected for oral presentation in the 47th Annual meeting of the American Society of Tropical Medicine and Hygiene in San Juan, Puerto Rico, October 18-22, 1998. 16. M. Bharadwaj, P. Vial, J. Botten, M. Cerda, G. Mertz and B. Hjelle. (1998). Andes virus-associated HPS in Chile: presence of viral RNA in tracheal aspirate suggests potential route for interpersonal transmission. Had been selected for presentation by the 4th International Conference on HFRS and Hantavirus in Atlanta, Georgia, March 5-7, 1998. 10 17. J. Rawlings, M. Bharadwaj, P. Rodriguez-Moran, B. Hicks, M. White, G. Moore, P. Hunt, and B. Hjelle. (1998). Update on Hantaviruses and HPS in Texas. Presented at the 4th International Conference on HFRS and Hantavirus held in Atlanta, Georgia, March 5-7, 1998. 18. J.F. Ferrer, C. Jonsson, N. Esteban, D. Galligan, M.A. Bosombrio,M. PeraltaRamos, M. Bharadwaj, N. Torrez-Martinez, J. Callahan, A. Segovia, and B. Hjelle. (1998). Epidemiological features of SNV-Related Hantavirus Infection in high prevalence Gran Chaco Indian populations. Presented at the 4th International Conference on HFRS and Hantavirus held in Atlanta, Georgia, March 5-7, 1998. 19. P. Rodriguez-Moran, N. Torrez-Martinez, M. Bharadwaj, D. Goade, J. Rawlings, B. Hicks, B. Mix, and B. Hjelle. (1998). Bayou Hantavirus Pulmonary Syndrome in Texas: Identification of the Rice Rat Oryzomys Palustris as the rodent reservoir host. Presented at the 4th International Conference on HFRS and Hantavirus held in Atlanta, Georgia, March 5-7, 1998. 20. E. Mackow, R. LaMonica, M. Fay, K. Springer, B. Hjelle, M. Bharadwaj, C. Schmaljohn, R. Shaw and I. Gravrilovskaya. (1998). Site-specific mutagenesis of the New York-1 virus nucleocapsid protein defines residues required for monoclonal antibody recognition of HPS-associated Hantaviruses. Presented at the 4th International Conference on HFRS and Hantavirus held in Atlanta, Georgia, March 5-7, 1998. 21. R.M. Feddersen, B. Hjelle, M. Bharadwaj, C. Barclay, L. Samengo. (1997). Microscopic pathologic findings and tissue distribution of hantavirus pulmonary syndrome due to Andes virus. Presented at the 46th annual meeting (December 7 11, 1997) of the American Society of Tropical Medicine and Hygiene, Orlando, Florida. 22. B. Hjelle, J. Salazar, N. Torrez-Martinez, M. Bharadwaj, F. Koster and T. Yates. (1996). New sigmodontine rodent-borne hantavirus from Bolivia. Presented at presented at the 15th annual meeting (July 13-17,1996) of the American Society of virology at the University of Western Ontario. 23. Mausumi Bharadwaj, Norah Torrez-Martinez, J. Salazer, T. Yates, J. Patton and Brian Hjelle. (1996). Rio Mamore Virus (RMV): newly-identified Bolivian hantavirus related to pathogenic North American strains. Presented at the 45th annual meeting (December 1-5, 1996) of the American Society of Tropical Medicine Hygiene. 24. Mausumi Bharadwaj and Oscar A. Bizzozero. (1995). Myelin Po glycoprotein 11 and the synthetic peptide IRYCWLRR are both autoacylated with palmitoyl-CoA. Presented at the annual meeting (March 5-9, 1995) of the American Society for Neurochemistry, Santa Monica, California. 25. Mausumi Bharadwaj and Kenneth D. Beaman. (1992). Purification of T-cell suppressor factor (TJ6) from pregnant murine uterine tissue. Presented at the Transplantation Immunology Workshop (Poster #29) in 21st annual autumn immunology conference held in Chicago on November 14-16, 1992. 26. Mausumi Sinha Ray, Dwaipayan Bharadwaj, and Ratha N. Hati. (1989). Modulation of a membrane-bound alkaline protease by unsaturated fatty acids. Poster (#ENZ-1) was presented at the 58th annual meeting of the Society of Biological Chemists (INDIA) held in Izatnagar, INDIA from October 16-18,1989. 27. Dwaipayan Bharadwaj, Mausumi Sinha Ray, and Ratha N. Hati. (1989). Presence of soluble pyroglutamate aminopeptidase (PGAP) activity in rat submaxillary gland. Post (#ENZ-3) was presented at the 58th annual meeting of the Society of Biological Chemists (INDIA) held Izatnagar, INDIA from October 1618, 1989. Selected for oral presentation. 12