Cisplatin
Cisplatin is an anti-cancer chemotherapy drug used to treat many types of cancer.
**Before and/or after the Cisplatin infusion, extra IV fluids are given, care is taken to ensure
adequate hydration before, during and after Cisplatin, to protect your kidney function.
Cisplatin Side Effects:
 Most people do not experience all of the Cisplatin side effects listed.
 Cisplatin side effects are almost always reversible and will go away after treatment is
complete.
 Nausea and vomiting (nausea may last up to 1 week after therapy, please follow
instructions for anti-nausea medication as directed).
 Kidney toxicity.
 Low blood counts.
 Numbness/tingling of the extremities (less common) may be noted.
**This may become progressively more severe with continued treatment, and your doctor
may decide to decrease your dose.
 High frequency hearing loss (ringing in the ears).
 Taste changes, metallic taste.
 Hair loss.
 Unusual bleeding or bruising.
Cisplatin Precautions:
 Before starting Cisplatin treatment, make sure you tell your doctor about any other
medications you are taking (including prescription, over-the-counter, vitamins, herbal
remedies, etc.). Do not take aspirin, products containing aspirin unless your doctor
specifically permits this.
 Do not receive any kind of immunization or vaccination without your doctor's approval
while taking Cisplatin.
 For both men and women: Do not conceive a child (get pregnant) while taking Cisplatin.
Barrier methods of contraception, such as condoms, are recommended. Discuss with your
doctor when you may safely become pregnant or conceive a child after therapy.
Cisplatin Self Care Tips:
 To reduce nausea, take anti-nausea medications as prescribed by your doctor, eat small
amounts of food frequently.
 Try dry cereal, toast, crackers especially in the morning to help curb nausea.
 Maintaining a good fluid intake is very important to help to avoid kidney damage.
Drink at least three quarts of fluid every 24 hours, unless you are instructed
otherwise.
 In general, drinking alcoholic beverages should be kept to a minimum or avoided
completely. You should discuss this with your doctor.
 Avoid sun exposure. Wear SPF 15 (or higher) sun block and protective clothing.
 Get plenty of rest.
 Maintain good nutrition.
 If you experience symptoms or side effects, be sure to discuss them with your health care
team. They can prescribe medications and/or offer other suggestions that are effective in
managing such problems.