The Leukemia & Lymphoma Society
Stohlman Scholar Scientific Symposium
Renaissance Scottsdale Resort
September 23 & 24, 2005
Thursday, September 22, 2005
Arrival
Friday, September 23, 2005
7:30 am
Continental Breakfast
8:00am
Welcome Remarks
Session I:
Involvement of TNF Receptor Superfamily in the Development
and Treatment of Leukemia & Lymphoma
8:15am
Genhong Cheng, Ph.D.: Stohlman Scholar
Regulation of Canonical and Noncanonical NF-B Activation by TNF Receptor
Associated Factors
Yang-Xin Fu, M.D., Ph.D.
TNFRF-Mediated Tumor Immunity: The Role of LIGHT
Lieping Chen, M.D., Ph.D.
Co-signal Manipulation in Leukemia and Lymphoma Therapy
Michael Alan Teitell, M.D., Ph.D.
Mechanisms in Germinal Center B Cell Transformation
8:45am
9:15am
9:45am
10:15am
Questions & Answers
10:30am
BREAK
Session II:
The Consequences of DNA Damage and Unfaithful DNA Repair in Leukemia Cells
10:45am
Tomasz Skorski, M.D., Ph.D., D.Sc.: Stohlman Scholar
Fusion Tyrosine Kinases - A Result and Cause of Genomic Instability
Maria Jasin, Ph.D.
The Dual Roles of DNA Double-Strand Break Repair in Mediating and Suppressing
Chromosomal Rearrangements and Malignant Transformation
Carolyn Felix, M.D.
Gene Environment Interactions in the Genesis of MLL Translocations
Richard Fishel, Ph.D.
Activation and signaling by MutS and MutL homologs
Richard Van Etten, M.D., Ph.D.
Altered Transforming and Leukemogenic Activity of Imatinib Resistant Bcr-Abl Mutants
11:10am
11:35am
Noon
12:25pm
12:50pm
Questions & Answers
1:05-2:30pm Luncheon
Stohlman Scholar Scientific Symposium
Renaissance Scottsdale Resort
Friday, September 23, 2005
Session III:
Mechanism-Based Cancer Immunotherapy
2:30pm
Eli Gilboa, Ph.D.
Immunological Control of Cancer - a Multi-Pronged Approach
Michel Sadelain, M.D., Ph.D.
Targeting Tumors with Genetically Enhanced Lymphocytes
Glenn Dranoff, M.D.; Stohlman Scholar
Sequential Cancer Immunotherapy
Carl June, M.D. (Saturday, Session V; 4:20 to 4:45)
Rebuilding Immunity in Myeloma after High Dose Chemotherapy
3:00pm
3:30pm
4:00pm
4:30pm
Questions & Answers
5:00-6:30pm Poster Session Set-up with Wine & Cheese
7:30pm
Dinner
Stohlman Scholar Scientific Symposium
Renaissance Scottsdale Resort
Saturday, September 24, 2004
8:00am
Breakfast Buffet
8:30am
Brian Druker, M.D.
Kenneth B. McCredie Lecture
Session IV:
Post-transcriptional Regulation of Gene Expression in Cancer
9:30am
Katherine Borden, Ph.D.: Stohlman Scholar
Nuclear Functions of the Translation Factor eIF4E Contribute to Oncogenic
Transformation
Nahum Sonenberg, Ph.D.
Control of Translation Initiation: Links to Cancer
Bruno Calabretta, Ph.D., M.D.
Anti-leukemia Effects of C/EBP/Alpha and C/EBPbeta, Two Genes Regulated at the
Translational Level
Jack Keene, Ph.D.
Functional Coordination of Gene Expression by RNA Operons
10:00am
10:30am
11:00am
11:30am
Questions & Answers
11:45-2:00pm Stars & Scholars Luncheon
2:00-3:15pm Poster Session & Dessert
Session V:
Ploidy, Genome Stability and Cancer
3:30pm
David Pellman, M.D.: Stohlman Scholar
Ploidy, Genome Stability and Cancer
3:55pm
4:20pm
4:45pm
5:10pm
Jerry Shay, Ph.D.
Telomeres and Telomerase in Response to DNA Damage Signaling
William Hahn, M.D., Ph.D. (Friday, Session III; 4:00pm to 4:30pm)
Telomerase, DNA Damage and Genomic Stability
Franziska Michor, Ph.D.
Can Genetic Instability Initiate Tumorigenesis?
Frederick Alt, Ph.D.
Role of NHEJ and the DSB Response in IgH Class Switching and in Suppressing
Oncogenic Translocations
5:35pm
Questions & Answers
5:50pm
Closing Remarks