CURRICULUM VITAE
David T. Felson, M.D., M.P.H.
Date of Birth: September 16, 1952
Place of Birth: Cincinnati, Ohio
Marital Status: Married
Professional address:
Boston University School of Medicine
715 Albany Street, X-200
Boston, MA 02118
Telephone: 617-638-5180
E-mail: dfelson@bu.edu
Home Address:
66 Cedar Street
Newton, MA 02459
Telephone: 617-969-7703
Current Appointments:
 Evans Scholar Professor of Medicine and Epidemiology
 Section Chief, Clinical Epidemiology Research and Training Unit, Department of
Medicine, Boston Medical Center
 Principal Investigator, Boston University N.I.H./N.I.A.M.S. Multidisciplinary Clinical
Research Center Grant
 Director of Training, Boston University Clinical and Translational Science Institute
 Professor of Medicine and Public Health, University of Manchester, United Kingdom
(part time)
CAREER OUTLINE
1974
1978
1978-1981
1981
1981-1984
1984
1984
1984-1989
1989-1994
19942008-
A.B., History and Biochemistry, Harvard College, Cambridge, MA Academic
Honors: National Merit Scholar 1970-1971, Harvard College Scholar 1970-1974,
Cum Laude general studies
M.D., The Johns Hopkins School of Medicine, Baltimore, MD
Internship and residency in Internal Medicine, Case Western University Hospitals,
Cleveland, OH
Board Certified in Internal Medicine
Clinical and Research Fellowship in Arthritis and Connective Tissue Disease,
Boston University School of Medicine, Boston, MA
Master's Degree in Public Health (M.P.H.), Boston University School of Public
Health, Boston, MA
Board Certified in Rheumatology
Assistant Professor of Medicine and Public Health (Epidemiology), Boston
University School of Medicine
Associate Professor of Medicine and Public Health (Epidemiology and
Biostatistics), Boston University School of Medicine
Professor of Medicine and Epidemiology, Boston University Schools of Medicine
and Public Health
Professor of Medicine and Public Health, University of Manchester, UK (part time)
AWARDS, HONORS AND HONORIFIC LECTURESHIPS
1991
1993
1999
1999
1999
2000
2000
2001
2001
2002
2003
2004
2003
2003
2003
2004
2004
2004
2004
2005
2006
2007
2008
2010
2010
2011
Recipient, Henry Kunkel Young Investigator Award, American College of
Rheumatology
Elected, American Society for Clinical Investigation (ASCI)
Recipient, Osteoarthritis Research Society Award for Clinical Science
Chair, NIH Conference on Osteoarthritis (Stepping Away from OA)
Annual Visiting Professor, Hospital for Special Surgery
Recipient, Distinguished Alumnus Award, Boston University School of Public
Health
Guest Lecturer, Israel Rheumatology Society
Engleman Lectureship, University of California, San Francisco
Recipient, American College of Rheumatology Clinical Research Award
Recipient, Henderson Lecture Award, American Geriatrics Society
Boland Lectureship, Mayo Clinic
Colegio Mexicano de Reumatologia, Profesor Invitado de 2003
Elected, Association of American Physicians (AAP)
N. Paul Strottmann Lecture, Univ. of Iowa
Chair, Novartis Foundation Symposium on Osteoarthritic Joint Pain
Dunlop Dotteridge Lecturer (Canadian Rheumatology Association)
Abbott Scholar Keynote Speaker
Ogryzlo Day Merck Frosst Visiting Professor, University of Toronto
Recipient, Howley Prize from the Arthritis Foundation
Pfizer Visiting Professor, Univ. California, San Diego
Cogen Lecture, Maine Medical Center
Robert Dawson Evans Research Mentoring Award, Boston University Medical
Center (inaugural)
Evans Scholar Award, Boston University School of Medicine (inaugural)
Knowles Lecture, Northern California Arthritis Foundation
Marian Ropes Award, Massachusetts Arthritis Foundation
Cutting Edge Rheumatology, Lund, Sweden
Medical Societies:
Fellow, American College of Rheumatology
Member, Society for Epidemiologic Research
Member, American Society for Clinical Investigation
Member, Orthopaedic Research Society
Member, Association of American Physicians (AAP)
Editorial Boards:
Arthritis and Rheumatism, 1989-1993
Arthritis Care and Research 1994-Current
Osteoarthritis and Cartilage 1997-Current
American Journal of Medicine 1998-2011
Journal of Rheumatology, 1998-Current
2
BMJopen, 2010-current
COMMITTEE PARTICIPATION
American College of Rheumatology (formerly American Rheumatism Association)
1985, 1986,
1992, 1995
Member, Abstract Selection committee, Health Services Research Subsection,
A.R.A. National Meetings
1988 &1993 Chairman, Abstract Selection Committee, Epidemiology/Health Services
Research Abstracts, A.C.R. National Meetings
1990 & 1994 Member, Manpower Committee
1990-1995
Member, Committee on Health Care Research
1991-1994
Chairman, Committee on Outcome Measures for Rheumatoid Arthritis Trials
1999
Member, Abstract Selection Committee, Cartilage and Osteoarthritis Pathogenesis,
ACR National Meeting
2005
CoChair, Abstract Selection Committee, Clinical Osteoarthritis, ACR
National Meeting
2003-4
Chair, Abstract Selection Committee, Clinical Osteoarthritis, ACR National
Meeting
2003Chair, ACR Committee to Reevaluate Improvement Criteria in Rheumatoid
Arthritis
2004-2005
Chair, Abstract Selection Committee, Epidemiology and Health Services Research,
ACR National Meeting
2004Member, Classification and Response Criteria Subcommittee, ACR
2009CoChair, Classification and Response Critieria Committee, ACR
Arthritis Foundation (A.F.)
1988-1990
1994-1995
2008
Member, Grants Subcommittee of the A.F. Research Committee
Member, Research Committee
Reviewer, A.F. National Grants Committee
Osteoarthritis Research Society International (OARSI)
2010. 2011
Reviewer, OARSI international meetings
National Arthritis Advisory Board - US Government
1987
Consultant on prevention of osteoarthritis
National Institutes of Health
1985-1991
1991
Member, Multipurpose Arthritis Center Site Visit teams
Chairman, Review panel for Minocycline in RA Coordinating Center
3
1993-1998
Member, Epidemiology Disease Control-1 AHC Study Section
1996-1997
Member, National Arthritis Data Workgroup
1997Chairman, National Arthritis Data Workgroup
1998
Member, Acupuncture in Osteoarthritis Review Panel
1998-2002
Member, Epidemiology Disease Control 1 Study Section
1999
Chair, Stepping Away from Osteoarthritis (1st Conference on OA prevention)
2000 Co-Chair, 2nd Biennial National Arthritis Research Conference
2001 Chair, RFA review, Preventing Disability in Osteoarthritis, NIAMS
2003Member. Osteoarthritis Initiative Steering Committee
2004-2008
Member, Skeletal Biology Skeletal Reconstruction Study Section
American Board of Internal Medicine (ABIM)
2001-2002
Member, Committee on Practice Management in Osteoarthritis (representing
American College of Physicians)
Food and Drug Administration
1993-97
Member, Arthritis Advisory Committee
Hospital and Department of Medicine
1991-1995
1995-1997
1997- 1998
Chair, Boston City Hospital Department of Medicine Quality Improvement
Committee
Chair, Boston Medical Center Department of Medicine Quality Improvement
Member, Research planning committee, Department of Medicine
University Teaching
19931993-
Coteach introductory course in Clinical Epidemiology, Boston University
School of Public Health
Coteach clinical epidemiology component of Essentials of Public Health course
to Boston University Medical Students
Industry
1997-2000
1997-2003
Chair, Data Safety Monitoring Board, ATTRACT trial (use of anti TNF in
rheumatoid arthritis, Centocor)
Chair, Data Safety Monitoring Board, Alexion Anti-C5 trial in rheumatoid arthritis
Commonwealth of Massachusetts
2006-
Member, Environmental Health Advisory Committee
4
PUBLICATIONS
Articles in peer reviewed journals
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Felson DT, Cupples LA, Meenan RF: Misuse of statistical methods in Arthritis and
Rheumatism: Articles from 1982 compared to articles from 1967-68. Arthritis Rheum 27(9):
1018-1022, 1984. [PMID:6332629]
Felson DT, Anderson JA: Evidence for the superiority of immunosuppressive drugs and
prednisone over prednisone alone in lupus nephritis: results of a pooled analysis. N Engl J
Med 311(24): 1528-1533, 1984.
Felson DT, Meenan RF, Dayno S, Gertman P: Referral of musculoskeletal disease patients by
family and general practitioners. Arthritis Rheum 28(10):1156-1162, 1985.
Singer AM, Naimark A, Felson DT, Shapiro J: Comparison of overhead and cross-table
lateral views for detection of knee joint effusions. Am J Roentgen 144: 973-975, 1985.
Goldenberg DL, Felson DT, Dinerman H: A randomized, controlled trial of amitriptyline and
naproxen in the treatment of patients with fibromyalgia, Arthritis Rheum 29(11):1371-1377,
1986.
Dinerman H, Goldenberg DL, Felson DT: A prospective evaluation of 118 patients with the
fibromyalgia syndrome - prevalence of Raynauds phenomenon, sicca symptoms, ANA, low
complement and Ig deposition at the dermal-epidermal junction. J Rheumatol 13: 368-373,
1986.
Felson DT, Goldenberg DL: The natural history of fibromyalgia. Arthritis Rheum 29: 15221526, 1986.
Felson DT, Anderson JJ: The association of steroid dosage and bolus steroids with avascular
necrosis of bone: an across study evaluation. Lancet 1:902-905, 1987.
Felson DT, Naimark A, Anderson J, Kazis L, Castelli W, Meenan R: The prevalence of knee
osteoarthritis in the elderly: The Framingham Knee Osteoarthritis Study. Arthritis Rheum
30:914-918, 1987.
Varga J, Idelson BA, Felson DT, Skinner M, Cohen AS: Lack of amyloid in abdominal fat
aspirates from patients undergoing long-term hemodialysis. Arch Intern Med 147:1455-1457,
1987.
Kiel DP, Felson DT, Anderson JJ, Wilson PWF, Moskowitz MA: Hip fracture and the use
of estrogens in postmenopausal women: the Framingham Study. N Engl J Med 317:11691174, 1987.
Simms RW, Goldenberg DL, Felson DT, Mason J: Tenderness in 75 anatomic sites:
distinguishing fibromyalgia patients from controls. Arthritis Rheum 31:182-187, 1988.
Anderson JJ, Felson DT: Factors associated with osteoarthritis of the knee in the first
National Health and Nutrition Examination Survey (HANES I). Am J Epidemiol 128: 179189, 1988.
Felson DT, Anderson JJ, Naimark A, Walker AM, Swift M, Meenan RF: Obesity and knee
osteoarthritis: the Framingham Study. Ann Intern Med 109:18-24, 1988.
Felson DT, Kiel DP, Anderson JJ, Kannel WB: Alcohol consumption and hip fractures: the
Framingham Study. Am J Epidemiol 128:1102-1110, 1988.
Felson DT: The epidemiology of knee and hip osteoarthritis. Epidemiol Reviews 10:1-28,
1988.
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Felson DT: Epidemiologic research in fibromyalgia. In: Proceedings of Symposium on
Fibromyalgia, Palm Springs, CA, March 1988. J Rheumatol 16 (suppl 19):7-11, 1989.
Felson DT, Anderson JJ, Naimark A, Hannan MT, Kannel WB, Meenan RF: Does smoking
protect against osteoarthritis? Arthritis Rheum 32:166-172, 1989.
Felson DT, Anderson JJ, Hannan MT, Milton RC, Wilson PWF, Kiel DP: Impaired vision
and hip fracture: The Framingham Study. J Am Geriatr Soc 37:495-500, 1989.
Anderson JJ, Felson DT, Meenan RF, Williams HJ: Which traditional measures should be
used in rheumatoid arthritis clinical trials? Arthritis Rheum 32:1093-1099, 1989.
Felson DT, Anderson JJ, Naimark A, Kannel W, Meenan RF: The prevalence of
chondrocalcinosis in the elderly and its association with osteoarthritis: The Framingham
Study. J Rheumatol 16:1241-1245, 1989.
Felson DT: Corticosteroids and avascular necrosis. In: Symposium: Clinical applications of
meta-analysis. Annals RCPSC 22:453-454, 1989.
Felson DT, Anderson JJ, Meenan RF: Time for changes in the design, analysis and reporting
of rheumatoid arthritis clinical trials. Arthritis Rheum 33:140-149, 1990.
Hannan MT, Felson DT, Anderson JJ, Naimark A, Kannel WB: Estrogen use and
knee
osteoarthritis in women: the Framingham Study. Arthritis Rheum 33:525532, 1990.
Guccione AA, Felson DT, Anderson JJ: Defining arthritis and measuring functional status in
elders: methodological issues in the study of disease and physical disability. Am J Public
Health 80:945-949, 1990.
Kiel DP, Felson DT, Hannan MT, Anderson JJ, Wilson PWF: Caffeine and the risk of hip
fracture: the Framingham Study. Am J Epidemiol 132:675-684, 1990.
Felson DT, Anderson JJ, Meenan RF: The comparative efficacy and toxicity of second line
drugs in rheumatoid arthritis: results of two meta-analyses. Arthritis Rheum 33:1449-1461,
1990.
Huckins D, Felson DT, Holick M: Treatment of psoriatic arthritis with oral 1,25dihydroxyvitamin D3: A pilot study. Arthritis Rheum 33:1723-1727, 1990.
Felson DT: The epidemiology of knee osteoarthritis: results from the Framingham
Osteoarthritis Study. Seminar Arthritis Rheum 20:3 (suppl 1):42-50, 1990.
Felson DT, Sloutskis D, Anderson JJ, Anthony J, Kiel DP: Thiazide diuretics and the risk of
hip fracture: results from the Framingham Study. JAMA 265:370-373, 1991.
Simms RW, Felson DT, Goldenberg D: Development of preliminary criteria for response to
treatment in fibromyalgia, J Rheumatol 18:1558-1563, 1991.
Felson DT: Clinical trials in rheumatoid arthritis under attack: Are practice-based
observational studies the answer? J Rheumatol 18:951-953, 1991.
Anderson JJ, Felson DT, Meenan RF: Secular changes in published rheumatoid arthritis
clinical trials. Arthritis Rheum 34:1304-1309, 1991.
Felson DT, Hannan MT, Naimark A, et al: Occupational physical demands, knee bending and
knee osteoarthritis: results from the Framingham Study. J Rheumatol 18:1587-1592, 1991.
Marder WD, Meenan RF, Felson DT, et al: The present and future adequacy of rheumatology
manpower: a study of health care needs and physician supply. Arthritis Rheum 34:1209-1217,
1991.
Felson DT, Zhang Y, Anthony JM, Naimark A, Anderson JJ: Weight loss reduces the risk of
symptomatic knee osteoarthritis in women: The Framingham Study. Ann Intern Med
116:535-539, 1992.
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Hannan MT, Anderson JJ, Pincus T, Felson DT: Educational attainment and osteoarthritis:
differential associations with radiographic changes and symptom reporting. J Clin Epidemiol
45:139-147, 1992.
Hannan MT, Felson DT, Anderson JJ: Bone mineral density in elderly men and women:
results from the Framingham Osteoporosis Study. J Bone Miner Res 7:547-553, 1992.
Simms RW, Zerbini CAF, Ferrante NB, Anthony J, Felson DT, Craven DE: Fibromyalgia
syndrome in patients infected with human immunodeficiency virus. Am J Med 92:368-374,
1992.
Kiel DP, Baron JA, Anderson JJ, Hannan MT, Felson DT: Cigarette smoking eliminates the
protective effect of oral estrogens on the risk of hip fracture among women. Ann Intern Med
116:716-721, 1992.
Felson DT: Bias in meta-analytic research. J Clin Epidemiol 45:885-892, 1992.
Felson DT, Anderson JJ, Meenan RF: Use of short-term efficacy/toxicity tradeoffs to select
second-line drugs in rheumatoid arthritis: a meta-analysis of published clinical trials. Arthritis
Rheum 35:1117-1125, 1992.
Pope JE, Anderson JJ, Felson DT: A meta-analysis of the effects of non-steroidal antiinflammatory drugs on blood pressure. Arch Intern Med 153:477-484, 1993.
Hannan MT, Felson DT, Anderson JJ, Naimark A: Habitual physical activity is not associated
with knee osteoarthritis: the Framingham Study. J Rheumatol 20:704-709, 1993.
Felson DT: Choosing a core set of disease activity measures for rheumatoid arthritis clinical
trials. J Rheumatol 20:531-534, 1993.
Felson DT, Zhang Y, Hannan MT, Anderson JJ: The effects of weight and body mass index
on bone mineral density in men and women: the Framingham Study. J Bone Miner Res
8:567-573, 1993.
Ginzler EM, Felson DT, Anthony J, Anderson JJ: Hypertension increases the risk of renal
deterioration in systemic lupus erythematosus. J Rheumatol 20:1694-1700, 1993.
Felson DT, Anderson JJ: Critique of meta-analysis of second-line antirheumatic drugs. J Clin
Epidemiol 46:315-319, 1993.
Felson DT, Anderson JJ, Boers M, et al: American College of Rheumatology preliminary
core set of disease activity measures for use in rheumatoid arthritis clinical trials. Arthritis
Rheum 36:729-740, 1993.
Felson DT, Zhang Y, Hannan MT et al: The effect of postmenopausal estrogen therapy on
bone density in elderly women. N Engl J Med 329:1141-1146, 1993.
Felson DT: Occupation and knee osteoarthritis: evidence from two population-based studies.
Acta Orthop Scand 64 (suppl 253):4-5, 1993.
Chan KA, Felson DT, Yood RA, Walker AM: Incidence of rheumatoid arthritis in central
Massachusetts. Arthritis Rheum: 36:1691-1696, 1993.
Hannan MT, Anderson JJ, Felson DT: Bone mineral density and knee osteoarthritis in elderly
men and women: the Framingham Study. Arthritis Rheum 36:1671-1680, 1993.
Rochon PA, Gurwitz JH, Simms RW, Fortin PR, Felson DT, Minaker KL, Chalmers TC: A
study of manufacturer supported trials of non-steroidal anti- inflammatory drugs. Arch Intern
Med 154:157-163, 1994.
Felson DT, Radin EL: What causes knee osteoarthrosis: are different compartments
susceptible to different risk factors? J Rheumatol 21:181-183, 1994.
Guccione AA, Felson DT, Anderson JJ, et al: Specific diseases and their effects on functional
limitations in elders in the Framingham Study. Am J Public Health 84:351-358, 1994.
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Chan KA, Felson DT, Yood RA, Walker AM: The lag time between onset of symptoms and
diagnosis of rheumatoid arthritis. Arthritis Rheum 37:814-820, 1994.
Boers M, Tugwell P, Felson DT, et al: WHO and ILAR core endpoints for symptom
modifying antirheumatic drugs in RA clinical trials. J Rheumatol 21 (41):86-89, 1994
Felson DT, Anderson JJ, Boers M, et al for the ACR Committee on Outcome Measures:
Reduced joint counts in rheumatoid arthritis clinical trials. Arthritis Rheum, 37:463-464,
1994.
Zantos D, Zhang Y, Felson D: The overall and temporal association of cancer with
polymyositis and dermatomyositis. J Rheumatol 21:1855-1859, 1994.
Felson DT, Anderson JJ, Meenan RF: The efficacy and toxicity of combination therapy in
rheumatoid arthritis: A meta-analysis. Arthritis Rheum 37:1487-1491, 1994.
Moher D, Felson D, Gotzsche P, Laupacis A, Pocock S, Sackett D, Tugwell P, Wells G: A
proposal for structured reporting of randomized clinical trials. JAMA 272:1926-1931, 1994.
Felson DT: Weight and osteoarthritis. Rheumatol 22 (43):7-9, 1995.
Felson DT for the Rheumatoid Arthritis Clinical Trial Archive Group (RACTAG). The effect
of age and renal function on the efficacy and toxicity of methotrexate in rheumatoid arthritis.
J Rheumatol 22:218-223, 1995
Bergquist SR, Felson DT, Prashker MJ, Freedberg KA: The cost-effectiveness of liver biopsy
in rheumatoid arthritis patients on methotrexate. Arthritis Rheum 38:326-333, 1995.
Felson DT, Anderson JJ, Boers M, et al: American College of Rheumatology preliminary
definition of improvement in rheumatoid arthritis. Arthritis Rheum 38:727-735, 1995.
Dieppe P, Brandt KD, Lohmander S, Felson D: Detecting and measuring disease
modification in osteoarthritis. The need for standardized methodology. J Rheumatol 22:201203, 1995.
Chernoff MC, Wang M, Anderson JJ, Felson DT: Problems and suggested solutions in
creating an archive of clinical trials data: an example of methotrexate trials in rheumatoid
arthritis. Controlled Clin Trials 16:342-355, 1995.
Felson DT, Zhang Y, Hannan MT, Kannel WB, Kiel DP: Alcohol intake and bone mineral
density in elderly men and women: The Framingham Study. Am J
Epidemiol 142:485492, 1995.
Oliveria S, Felson DT, Reed JI, Cirillo PA, Walker AM: The incidence of symptomatic hand,
hip and knee osteoarthritis in a health maintenance organization. Arthritis Rheum 38:11341141, 1995.
Felson DT, Zhang Y, Hannan MT, Naimark A, Weissman B, Aliabadi P, Levy D. The
incidence and natural history of knee osteoarthritis in the elderly: The Framingham
Osteoarthritis Study. Arthritis Rheum 38:1500-1505, 1995.
Felson DT: Validating markers in osteoarthritis. Acta Orthop Scand 66 (suppl 266): 205-207,
1995.
McAlindon T, Zhang Y, Hannan M, Naimark A, Weissman B, Castelli W, Felson D: Are risk
factors for patellofemoral and tibiofemoral knee osteoarthritis different? J Rheumatol 23:332337, 1996.
McAlindon T, Jacques P, Zhang Y, Hannan MT, Aliabadi P, Weissman B, Rush D, Levy D,
Felson D: Do antioxidant micronutrients protect against the development and progression of
knee osteoarthritis? Arthritis Rheum 39:648-656, 1996.
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Chaisson CE, McAlindon TE, Felson DT, Naimark A, Wilson PWF, Sawin CT: Lack of
association between thyroid status and chondrocalcinosis or osteoarthritis: The Framingham
Osteoarthritis Study. J Rheumatol 23:711-715, 1996.
Kennedy M, Felson D: A prospective long-term study of fibromyalgia syndrome. Arthritis
Rheum 39: 682-685, 1996.
Oliveria SA, Felson DT, Klein RA, Reed JI, Walker AM: Estrogen replacement therapy and
the development of osteoarthritis. Epidemiology 7:415-419, 1996
Kiel DP, Zhang Y, Hannan MT, Anderson JJ, Baron J, Felson DT: The effect of smoking at
different life stages on bone mineral density in elderly men and women. Osteopor Intl 6:240248, 1996.
Felson DT: Does excess weight cause osteoarthritis and, if so, why? Ann Rheum Dis, 668670, 1996.
Nevitt MC, Felson DT: Sex hormones and osteoarthritis: epidemiological evidence. Ann
Rheum Dis 55: 673-676, 1996.
Felson D: Weight and osteoarthritis. Am J Clin Nutr 63:430S-432S, 1996.
Zhang Y, Glynn RJ, Felson DT: Musculoskeletal disease research: should we analyze the
joint or the person? J Rheumatol 23:1130-1134, 1996.
McAlindon T, Felson DT, Zhang Y, Hannan MT, Aliabadi P, Weissman B, Rush D, Wilson
PWF, Jacques P: The relationship between intake and serum levels of vitamin D and
progression of knee osteoarthritis among participants in the Framingham Study. Ann Intern
Med 125: 353-359, 1996.
Zhang Y, Kiel DP, Kreger BE, Cupples LA, Ellison RC, Dorgan JF, Schatzkin A, Levy D,
Felson DT: Bone mass and risk of breast cancer among postmenopausal women: the
Framingham Study. N Engl J Med 336:611-617, 1997.
Felson DT, Zhang Y, Hannan MT, Naimark A, Weissman B, Aliabadi P, Levy D: Risk
factors for incident radiographic knee osteoarthritis in the elderly: the Framingham Study.
Arthritis Rheum 40:728-733, 1997.
Lohmander LS, Felson DT: Defining the role of molecular markers to monitor disease,
intervention, and cartilage breakdown in osteoarthritis. J Rheumatol 24: 782-785, 1997.
Felson DT, McAlindon TE, Anderson JJ, Naimark A, Weissman BW, Aliabadi P, Evans S,
Levy D, LaValley MP: Defining radiographic osteoarthritis for the whole knee. Osteoarthritis
Cart 5:241-250, 1997.
Chaisson CE, Zhang Y, McAlindon TE, Hannan MT, Aliabadi P, Naimark A, Levy D, Felson
DT: Radiographic hand osteoarthritis: incidence, patterns and influence of preexisting disease
in a population based sample. J Rheumatol 24:1337-1343, 1997.
Kiel DP, Myers RH, Cupples LA, Kong XF, Zhu XH, Ordovas J, Schaefer EJ, Felson DT,
Rush D, Wilson PWF, Eisman JA, Holick MF: The BsmI Vitamin D receptor restriction
fragment length polymorphism (bb) influences the effect of calcium intake on bone mineral
density. J Bone Miner Res 12:1049-1057, 1997.
Giannini EH, Ruperto N, Ravelli A, Lovell D, Felson DT, Martini A: Preliminary definition
of improvement in juvenile arthritis. Arthritis Rheum 40: 1202-1209, 1997.
McAlindon T, Felson DT: Nutrition-risk factors for osteoarthritis. Ann Rheum Dis 56:397402, 1997.
Kauppila LI, McAlindon T, Evans S, Wilson PWF, Kiel D, Felson DT: Disc degeneration,
back pain and calcification of the abdominal aorta: a 25 year follow-up study in Framingham.
Spine 22:1642-1647, 1997.
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Jacques PF, Felson DT, Tucker KL, Mahnken B, Wilson PWF, Rosenberg IH, Rush D:
Plasma 25-hydroxyvitamin D and its determinants in an elderly population sample. Am J Clin
Nutr 66:929-936, 1997.
Cranney A, Tugwell P, Cummings S, Sambrook P, Adachi J, Silman AJ, Gillespie WJ,
Felson DT, Shea B, Wells G: Osteoporosis clinical trials endpoints: candidate variables and
clinimetric properties. J Rheumatol 24(6):1222-9, 1997.
Lawrence RC, Helmick CG, Arnett FC, Deyo RA, Felson DT et al: Prevalence estimates of
arthritis and selected musculoskeletal disorders in the United States. Arthritis Rheum 41:778799, 1998. [PMID:9588729]
Fraenkel L, LaValley M, Felson D: The use of radiographs to evaluate shoulder
pain in the emergency department. Am J Emer Med 16:560-563, 1998. [PMID:9786537]
Visser M, Harris T, Langlois J, Hannan MT, Roubenoff R, Felson DT, Wilson PWF, Kiel
DP: Body fat and skeletal muscle mass in relation to physical disability in very old men and
women of the Framingham Heart Study. J Gerontol (Med Sci), 53A:M214-M221, 1998.
[PMID:9597054]
Sharma L, Felson DT: Studying how osteoarthritis causes disability: nothing is simple. J
Rheumatol 25:1-4, 1998. [PMID:9458193]
Felson DT, Couropmitree NN, Chaisson CE et al: Evidence for a Mendelian gene in a
segregation analysis of generalized radiographic osteoarthritis: the Framingham Study.
Arthritis Rheum 41:1064-1071, 1998. [PMID:9627016]
Felson DT, Zhang Y: An update on the epidemiology of knee and hip osteoarthritis with a
view to prevention. Arthritis Rheum 41:1343-1355, 1998. [PMID:9704632]
Fraenkel L, Roubenoff R, LaValley M, McAlindon T, Chaisson C, Evans S, Harris T,
Dinarello CA, Felson DT: The association of peripheral monocyte derived
interleukin 1
beta, interleukin 1 receptor antagonist and tumor necrosis factor alpha with osteoarthritis in
the elderly. J Rheumatol 25:1820-1826, 1998. [PMID:9733466]
Felson DT, Anderson JJ, Lange MLM, Wells G, LaValley MP: Should improvement in
rheumatoid arthritis clinical trials be defined as 50 or 70% improvement in core set measures,
rather than 20%? Arthritis Rheum 41:1564-1570, 1998. [PMID:9751088]
Kauppila LI, Eustace S, Kiel DP, Felson DT, Wright AM: Degenerative displacement of
lumbar vertebrae: a 25 year follow-up in Framingham. Spine 23:1868-1873 1998.
[PMID:9762744]
Zhang Y, Hannan MT, McAlindon TE, LaValley MP, Evans S, Felson DT: Estrogen
replacement therapy and worsening of radiographic knee osteoarthritis: the Framingham
Study. Arthritis Rheum 41:1867-1873, 1998. [PMID:9778229]
Felson DT: Preventing knee and hip osteoarthritis. Bull Rheum Dis 47:1-4, 1998.
[PMID:9838735]
Fraenkel L, Zhang Y, Trippel SB, McAlindon TE, LaValley MP, Assif A, Adams K, Evans
S, Felson DT: Longitudinal analysis of the relationship between serum insulin-like growth
factor-1 and radiographic knee osteoarthritis. Osteoarthritis Cart 6:362-367, 1998.
[PMID:10197171]
Fraenkel L, Zhang Y, Chaisson CE, Evans SR, Wilson PWF, Felson DT: The association of
estrogen replacement therapy and Raynaud’s phenomenon in postmenopausal women. Ann Intern Med, 129:208-211, 1998. [PMID:9696729]
10
108. Oliveria SA, Felson DT, Cirillo PA, Reed JI, Walker AM: Body weight, body mass index
and incident symptomatic osteoarthritis of the hand, hip and knee. Epidemiology 10:161-166,
1998. [PMID:10069252]
109. Visser M, Kiel DP, Langlois J, Hannan MT, Felson DT, Wilson PW, Harris TB: Muscle
mass and fat mass in relation to bone mineral density in very old men and women: the
Framingham Heart Study. Appl Rad Isotopes 49:745-747, 1998. [PMID:9569599]
110. Felson DT, Lafyatis R, Korn J: Rheumatoid arthritis: Biological agents: is the
promise realized? Lancet 352 (IV):25, 1998. [PMID:9872172]
111. Chaisson CE, Zhang Y, Sharma L, Kannel W, Felson DT: Grip strength and the
risk of
developing radiographic hand osteoarthritis: results from the Framingham
Study.
Arthritis Rheum 42:33-38, 1999. [PMID:9920011]
112. Sharma L, Hayes KW, Felson DT, Buchanan TS, Kirwan-Mellis BS, Congrong L et al:
Does laxity alter the relationship between strength and physical function in knee
osteoarthritis? Arthritis Rheum 42:25-32, 1999. [PMID:9920010]
113. Gestel AM, Anderson JJ, van Riel, PLCM, Boers M, Haagsma CJ, Rich W, Wells G, Wells
G, Lange MLM, Felson DT: ACR and EULAR improvement criteria have comparable
validity in rheumatoid arthritis trials. J Rheumatol 26:705-711, 1999. [PMID:10090187]
114. Fraenkel L, Zhang Y, Brand F, Maricq H, Felson DT: Different factors influencing the
expression of Raynaud’s Phenomenon in men and women. Arthritis Rheum 42:306-310,
1999. [PMID:10025925]
115. McAlindon TE, Aliabadi P, Weissman B, Wilson PWF, Felson DT: Level of physical activity
and risk of incident radiographic and symptomatic knee osteoarthritis in an elderly sample:
the Framingham Study. Am J Med 106:151-157, 1999. [PMID:10230743]
116. Sharma L, Lou C, Felson DT, Dunlop DD, Hayes KW, Kirwan-Mellis G, Buchanan TW:
Laxity in healthy and osteoarthritic knees. Arthritis Rheum 42:861-870, 1999.
[PMID:10323441]
117. Molenaar ETH, Boers M, van der Heide DMFM, Felson D et al.: Strand V: Imaging in
rheumatoid arthritis: results of group discussions (OMERACT 4). J Rheumatol 26:749-751,
1999. [PMID:10090196]
118. Felson DT, Nevitt MC: Estrogen and osteoarthritis: how do we explain conflicting study
results? Preventive Med 28:445-448, 1999. [PMID:10329332]
119. Amin S, LaValley MP, Simms RW, Felson DT: The role of vitamin D in corticosteroidinduced osteoporosis: a meta-analytic approach. Arthritis Rheum 42:1740-1751, 1999.
[PMID:10446876]
120. LaValley MP, Felson DT: Early stopping of clinical trials in lupus and other rare
rheumatologic diseases. Lupus 8:698-703, 1999. [PMID:10568909]
121. Allaire SH, LaValley MP, Evans SR, O’Connor GT, Meenan RF, Levy D, Felson DT:
Evidence for decline in disability and improved health among persons aged 55 to 70 years:
the Framingham Study. Am J Public Health 89:1678-1683, 1999. [PMID:10553388]
122. Felson DT, LaValley MP, Baldassare AR, Block JA, Caldwell JR, Cannon GW, et al: A
randomized double blind sham-controlled trial of the Prosorba Column for treatment of
refractory rheumatoid arthritis. Arthritis Rheum 42:2153-2159, 1999. [PMID:10524687]
123. Gale DR, Chaisson CE, Totterman SM, Schwartz RK, Gale ME, Felson D: Meniscal
subluxation: association with osteoarthritis and joint space narrowing. Osteoarthritis Cart
7:526-532, 1999. [PMID:10558850]
11
124. Fraenkel L, Shearer P, Mitchell P, LaValley M, Feldman J, Felson DT: Improving the
selective use of plain radiographs in the initial evaluation of shoulder pain. J Rheumatol
27:200-204, 2000. [PMID:10648039]
125. Edmond S, Felson DT: Prevalence of back symptoms in elders. J Rheumatol 27:220-225,
2000. [PMID:10648042]
126. Anderson JJ, Wells G, Verhoeven AC, Felson DT: Factors predicting response to treatment
in rheumatoid arthritis: the importance of disease duration. Arthritis Rheum 43:22-29, 2000.
[PMID:10643696]
127. McAlindon TE, LaValley MP, Gulin JP, Felson DT: Glucosamine and chondroitin for
treatment of osteoarthritis: a systematic quality assessment and meta-analysis. JAMA
283:1469-1475, 2000. [PMID:10732937]
128. Hannan MT, Felson DT, Pincus T: Analysis of the discordance between radiographic changes
and knee pain in osteoarthritis of the knee. J Rheumatol 27:1513 –1517, 2000.
[PMID:10852280]
129. Fraenkel L, Tofler GH, Zhang Y, Silbershatz H, D’Agostino RB, Wilson PWF, Felson DT:
The associations between plasma levels of von Willebrand Factor and fibrinogen with
Raynaud’s phenomenon in men and women. Am J Med 108:583-586, 2000.
[PMID:10806290]
130. Zhang YQ, Hannan MT, Chaisson CE, McAlindon TE, Evans SR, Aliabadi P, Levy D,
Felson DT: Bone mineral density and risk of incident and progressive radiographic knee
osteoarthritis in women: The Framingham Study. J Rheumatol, 27:1032-1037, 2000.
[PMID:10782833]
131. Elahi S, Cahue S, Felson DT, Engelman L, Sharma L: The association between varusvalgus alignment and patellofemoral osteoarthritis. Arthritis Rheum 43(8): 1874-1880,
2000. [PMID:10943879]
132. Felson DT, McAlindon TE: Glucosamine and chondroitin for osteoarthritis: to recommend
or not to recommend. Arthritis Care Res 13:179-182, 2000. [PMID:14635271]
133. Chaisson CE, Gale DR, Gale E, Kazis L, Skinner K, Felson DT: Detecting radiographic
knee osteoarthritis: what combination of views is optimal? Rheumatology 39:1218-1221,
2000. [PMID:11085800]
134. Felson DT, Lawrence RC, Dieppe PA, Hirsch R, Helmick C: Osteoarthritis: The disease
and its prevalence and impact. In: Felson DT, conference chair. Osteoarthritis, New
Insights Part 1: The Disease and its Risk Factors. Ann Intern Med 133:635-646, 2000.
[PMID:11033593]
135. Felson DT, Yanovski SZ, Ateshian G, Sharma L, Buckwalter JA, Brandt KD: Local
biomechanical factors and osteoarthritis. In: Felson DT, conference chair. Osteoarthritis,
New Insights Part 1: The Disease and its Risk Factors. Ann Intern Med 133:635-646, 2000.
136. Hochberg MC, McAlindon T, Felson DT: Systemic and topical treatments. In Felson DT,
conference chair. Osteoarthritis, New Insights Part 2: Treatment approaches. Ann Intern
Med 133:726-737, 2000. [PMID:11074906]
137. Hannan MT, Tucker K, Dawson-Hughes B, Cupples, LA, Felson DT, Kiel DP. Effect of
dietary protein on bone loss in elderly men and women: The Framingham Osteoporosis
Study. J Bone Miner Res 15:2504-2512, 2000. [PMID:11127216]
138. Amin S, Zhang Y, Sawin CT, Evans SR, Hannan MT, Kiel DP, Wilson PWF, Felson DT:
The association of hypogonadism and estradiol levels with bone mineral density in elderly
men: The Framingham Study. Ann Intern Med 133:951-963, 2000. [PMID:11119396]
12
139. Chaisson CE, Zhang Y, Sharma L, Felson DT: Higher grip strength increases the risk of
incident radiographic osteoarthritis in proximal hand joints. Osteoarthritis Cart 8 (suppl
A):S29-32, 2000. [PMID:11156491]
140. Hannan MT, Felson DT, Dawson-Hughes B, Tucker KL, Cupples LA, Wilson PWF, Kiel
DP: Risk Factors for longitudinal bone loss in elder men and women: the Framingham
Osteoporosis Study. J Bone Miner Res 15:710-720, 2000. [PMID:10780863]
141. Furst D, Felson D, Thoren G, Gendreau RM: Immunoabsorption for the treatment of
rheumatoid arthritis: final results of a randomized trial. Ther Apheresis 4:363-373, 2000.
[PMID:11111818]
142. Zhang Y, Felson DT, Ellison RC, Kreger BE, Schatzkin A, Dorgan JF, Cupples LA, Levy
D, Kiel DP: Bone mass and the risk of colon cancer among post-menopausal women: The
Framingham Study. Am J Epidemiol 153:31-37, 2001. [PMID:11159144]
143. LaValley MP, McAlindon TE, Chaisson CE, Levy D, Felson DT: The validity of different
definitions of radiographic worsening for longitudinal studies of knee osteoarthritis. J Clin
Epidemiol 54: 30-39, 2001. [PMID:11165466]
144. Hill CL, Zhang Y, Sigurgeirsson B, Pukkala E, Mellemkjaer L, Airio A, Evans SR, Felson
DT: Increased incidence of specific cancer types in dermatomyositis and polymyositis:
combined population data from three Nordic countries. Lancet 357:96-100, 2001.
[PMID:11197446]
145. Felson DT, Chaisson CE, Hill CL, Totterman, SMS, Gale ME, Skinner KM, Kazis LE,
Gale DR: The association of bone marrow lesions with pain in knee osteoarthritis. Ann
Intern Med 134:541-549, 2001. [PMID:11281736]
146. Fraenkel L, Bogardus S, Concato J, Felson D: Preference for disclosure of information
among patients with rheumatoid arthritis. Arthritis Care Res 45:136-139, 2001.
[PMID:11324776]
147. Nevitt MC, Felson DT, Williams EN, Grady D for the Heart and Estrogen/Progestin
Replacement Study (HERS) Research Group: The effect of estrogen plus progestins on
knee symptoms and related disability in postmenopausal women: the HERS trial. Arthritis
Rheum 44:811-818, 2001. [PMID:11315920]
148. Felson DT, Anderson JJ: A review of the discriminant validity of outcome measures in
rheumatoid arthritis. J Rheumatol 28:422-426, 2001. [PMID:11246690]
149. Hill CL, Gale DG, Chaisson CE, Skinner K, Kazis L, Gale ME, Felson DT: Knee
effusions, popliteal cysts and synovial thickening: association with knee pain in those with
and without osteoarthritis. J Rheumatol 28:1330-1337, 2001. [PMID:11409127]
150. LaValley M, McAlindon TE, Evans S, Chaisson CE, Felson DT: Problems in the
development and validation of questionnaire-based screening instruments for ascertaining
cases with symptomatic knee osteoarthritis: the Framingham Study, Arthritis Rheum
44:1105-1113, 2001. [PMID:11352242]
151. Fraenkel L, Felson, DT: Rheumatologists’ attitudes towards routine screening for
hydroxychloroquine retinopathy. J Rheumatol 28:1218-1221, 2001. [PMID:11409112]
152. Felson DT: The verdict favors NSAID’s for treatment of osteoarthritis and a plea for more
evidence on other treatments. Arthritis Rheum 44:1477-1480, 2001. [PMID:11465696]
13
153. Wells G, Anderson J, Beaton D, Bellamy N, Boers M, Bombardier C, Breedveld F, Carr A,
Cranney A, Dougados M, Felson D, Kirwan J, Schiff M, Shea B, Simon L, Smolen J,
Strand V, Tugwell P, van Riel P, Welch VA. Minimal clinically important difference
module: summary, recommendations, and research agenda. J Rheumatol 28(2):452-4,
2001. [PMID:11246695]
154. Zhang Y, Seshadri S, Ellison RC, Heeren T, Felson DT: Bone mineral density and verbal
memory impairment: The Third National Health and Nutrition Examination Survey. Am J
Epidemiol 154:795-802, 2001. [PMID:11682361]
155. Zhang Y, Xu L, Nevitt MC, Aliabadi P, Yu W, Qin M, Lui LY, Felson DT: Comparison of
knee osteoarthritis prevalence between Chinese elderly in Beijing and Caucasians in the
U.S.: the Beijing Osteoarthritis Study. Arthritis Rheum 44:2065-2071, 2001.
[PMID:11592368]
156. Sharma L, Song J, Felson DT, Cahue S, Shamiyeh E, Dunlop DD: The role of knee
alignment in disease progression and functional decline in knee osteoarthritis. JAMA
286:188-195, 2001. [PMID:11448282]
157. Baker KR, Nelson ME, Felson DT, Layne JE, Sarno R, Roubenoff R: The efficacy of
home-based, progressive strength training in older adults with knee osteoarthritis: a
randomized controlled trial. J Rheumatol 28:1655-1665, 2001. [PMID:11469475]
158. Kiel D, Hannan M, Broe K, Felson D, Cupples LA: Can metacarpal cortical area predict
the occurrence of hip fracture in women and men over three decades of follow-up? Results
from the Framingham Osteoporosis Study. J Bone Miner Res 16:2260-2266, 2001.
[PMID:11760840]
159. Anderson JJ, Baron G, van der Heijde D, Felson DT, Dougados M: Ankylosing spondylitis
assessment group preliminary definition of short-term improvement in ankylosing
spondylitis. Arthritis Rheum 44(8):1876-86, 2001. [PMID:11508441]
160. Felson DT, Anderson JJ: Hyaluronan injections for osteoarthritis: hope, hype and hard
truths. Arch Intern Med 162:245-247, 2002. [PMID:11822915]
161. Baldwin CT, Cupples LA, Joost O, Demissie S, Chaisson C, McAlindon T, Myers RH,
Felson DT: Absence of linkage or association for osteoarthritis with the vitamin D
receptor/Type II collagen locus: the Framingham Osteoarthritis Study. J Rheumatol
29:161-165, 2002. [PMID:11824954]
162. Samelson EJ, Zhang YQ, Kiel DP, Hannan MT, Felson DT: Effect of birth cohort on risk
of hip fracture: age-specific incidence rates in the Framingham Study. Am J Public Health
92:858-62, 2002. [PMID:11988460]
163. Kerrigan DC, Lelas JL, Goggins J, Merriman GJ, Kaplan RJ, Felson DT: Effectiveness of a
lateral wedged insole on knee varus torque in patients with knee osteoarthritis. Arch Phys
Med Rehab 83: 889-893, 2002. [PMID:12098144]
164. Luepongsak N, Amin S, Krebs DE, McGibbon CA, Felson DT: The contribution of daily
activity to loading across the hip and knee joints in the elderly. Osteoarthritis Cart 10:353359, 2002. [PMID:12027536]
165. Fraenkel L, Bogardus S, Concato J, Felson D: Unwillingness of rheumatoid arthritis
patients to risk adverse effects. Rheumatology 41:253-261, 2002. [PMID:11934960]
166. LaValley MP, Felson DT: Statistical presentation and analysis of ordered categorical
outcome data in rheumatology journals. Arthritis Rheum 47:255-259, 2002.
[PMID:12115154]
14
167. Hill CL, LaValley MP, Felson DT: Secular changes in the quality of published randomized
clinical trials in rheumatology. Arthritis Rheum 46:779-784, 2002. [PMID:11920415]
168. Demissie S, Cupples LA, Myers R, Aliabadi P, Levy D, Felson DT: Genome scan for
quantity of hand osteoarthritis: the Framingham Study. Arthritis Rheum 46:946-952, 2002.
[PMID:11953971]
169. Yoshida S, Aoyagi K, Felson DT, Aliabadi P, Shindo H, Takemoto T: Comparison of the
prevalence of radiographic osteoarthritis of the knee and hand between Japan and the
United States. J Rheumatol 29:1454-1458, 2002. [PMID:12136905]
170. Felson DT, Nevitt MC, Zhang Y, Aliabadi P, Baumer B, Gale D, Li W, Yu W, Xu L: High
prevalence of lateral knee osteoarthritis in Beijing Chinese compared with Framingham
Caucasians. Arthritis Rheum 46:1217-1222, 2002. [PMID:12115226]
171. Anderson JJ, Ruwe M, Miller DR, Kazis L, Felson DT, Prashker M: Relative costs and
effectiveness of specialist and general internist ambulatory care for patients with two
chronic musculoskeletal conditions. J Rheumatol 29:1488-95, 2002. [PMID:12136910]
172. Amin S, LaValley MP, Simms RW, Felson DT: The comparative efficacy of drug therapies
used for the management of corticosteroid-induced osteoporosis: a meta-regression. J Bone
Miner Res 17:1512-1526, 2002. [PMID:12162505]
173. Hill CL, LaValley MP, Felson DT: Discrepancy between published report and actual
conduct of randomized clinical trials. J Clin Epidemiol 55:783-786, 2002.
[PMID:12384192]
174. Nevitt MC, Xu L, Zhang Y, Lui L-Y, Yu W, Lane N, Qin M, Hochberg M, Cummings S,
Felson DT: Very low prevalence of hip osteoarthritis among Chinese elderly in Beijing
compared to Caucasians in the U.S.: the Beijing Osteoarthritis Study. Arthritis Rheum
46:1773-1779, 2002. [PMID:12124860]
175. Felson DT, Buckwalter J: Debridement and lavage for osteoarthritis of the knee? N Engl J
Med 347:132-133, 2002. [PMID:12110742]
176. Zhang Y, Niu J, Kelly-Hayes M, Chaisson CE, Aliabadi P, Felson DT: Prevalence of
symptomatic hand osteoarthritis and its impact on functional status among elderly: the
Framingham Study. Am J Epidemiol 156:1021-1027, 2002. [PMID:12446258]
177. Tucker KL, Chen H, Hannan MT, Cupples LA, Wilson PWF, Felson D, Kiel DP: Bone
mineral density and dietary patterns in older adults: the Framingham Osteoporosis Study.
Am J Clin Nutr 76: 245-252, 2002. [PMID:12081842]
178. Zhang Y, Felson DT, Kiel DP: Bone mass and the risk of prostate cancer: the Framingham
study. Am J Med 113: 734-739, 2002. [PMID:12517363]
179. Bhattacharyya T, Gale D, Dewire P, Totterman S, Gale ME, McLaughlin S, Einhorn T,
Felson DT: The clinical importance of meniscal tears found by magnetic resonance
imaging in osteoarthritis of the knee. J Bone Joint Surg 85(1):4-9, 2003. [PMID:12533565]
180. Pincus T, Strand V, Koch G, Amara I, Crawford B, Wolfe F, Cohen S, Felson D: An index
of three core data set patient questionnaire measures distinguishes efficacy of active
treatment from placebo as effectively as the ACR20 response or disease activity score
(DAS) in a rheumatoid arthritis trial. Arthritis Rheum 48: 625-630, 2003.
[PMID:12632413]
181. Edmond SL, Felson DT: Function and back symptoms in older adults. J Am Geriatr Soc
51(12):1702-1709, 2003. [PMID:14687347]
182. Fraenkel L, Bogardus S, Concato J, Felson D. Risk communication in RA. J Rheumatol
30:443-448, 2003. [PMID:12610798]
15
183. Felson DT: Assessing the efficacy and safety of rheumatic disease treatments: obstacles
and proposed solutions. Arthritis Rheum 48(7):1781-1787, 2003. [PMID:12847670]
184. Boers M, Anderson JJ, Felson DT. Deriving an operational definition of low disease
activity state in RA. J Rheumatol 30:1108-1109, 2003. [PMID:12734919]
185. Wells G, Boers M, Shea B, Anderson J, Felson D, et al. MCID/Low Disease Activity state
workshop: low disease activity state in rheumatoid arthritis. J Rheumatol 30: 1110-1111,
2003. [PMID:12734918]
186. Wells G, Anderson J, Boers M, Felson D, et al. MCID/Low Disease Activity State
Workshop: summary, recommendations and research agenda. J Rheumatol 30: 1115-1118,
2003. [PMID:12734920]
187. Niu J, Zhang Y, LaValley M, Chaisson CE, Aliabadi P, Felson DT. Symmetry and
clustering of symptomatic hand osteoarthritis in elderly men and women: the Framingham
Study. Rheumatol. 42:343-348, 2003. [PMID:12595633]
188. Zhang Y, Xu, L, Nevitt MC, Niu J, Goggins JP, Aliabadi P, Yu W, Lui LY, Felson DT:
Lower prevalence of hand osteoarthritis among Chinese subjects in Beijing compared with
White subjects in the United States. Arthritis Rheum 48:1034-1040, 2003.
[PMID:12687546]
189. Anderson JJ, Bolognese JA, Felson DT: Comparison of rheumatoid arthritis clinical trial
outcome measures: a simulation study. Arthritis Rheum 48(11):3031-3038, 2003.
[PMID:14613263]
190. Hill CL, Gale DG, Chaisson CE, Skinner K, Kazis L, Gale ME, Felson DT: Periarticular
lesions detected on magnetic resonance imaging: prevalence in knees with and without
knee symptoms. Arthritis Rheum 48 (10): 2836-2844, 2003. [PMID:14558089]
191. Felson DT, McLaughlin S, Goggins J, LaValley MP, Gale ME, Totterman S, Li W, Hill C,
Gale D: Bone marrow edema and its relation to progression of knee osteoarthritis. Ann
Intern Med 139: 330-336, 2003. [PMID:12965941]
192. Brighton B, Bhandari M, Tornetta P, Felson DT: Hierarchy of evidence: from case reports
to randomized controlled trials. Clin Orthop Rel Res 413: 19-24, 2003. [PMID:12897592]
193. Xu L, Nevitt MC, Zhang YQ, Aliabadi P, Felson DT: High prevalence of knee, but not hip
or hand osteoarthritis in Beijing elders: comparison with data of Caucasians in the United
States. J Chinese Med Assoc 83: 1206-1209, 2003 (in Chinese). [PMID:12930631]
194. Lo GH, LaValley M, McAlindon T, Felson DT: Intraarticular hyaluronic acid in treatment
of knee osteoarthritis. A meta-analysis. JAMA 290:3115-3121, 2003. [PMID:14679274]
195. Miller RR, Zhang Y, Silliman R, Kelly-Hayes M, Leveille S, Murabito J, Kiel D,
O’Connor G, Felson DT. Effect of medical conditions on improvement in self-reported and
observed functional performance of elders. J Am Geriatr Soc 52:217-223, 2004.
[PMID:14728630]
196. Amin S, Luepongsak N, McGibbon C, LaValley M, Krebs D, Felson DT: Knee adduction
moment and development of chronic knee pain in elders. Arthritis Rheum 51(3): 371-376,
2004. [PMID:15188321]
197. Dunn JE, Link CL, Felson DT, Crincoli MG, Keysor JJ, McKinlay JB. Prevalence of foot
and ankle conditions in a multi-ethnic community sample of older adults. Am J Epidemiol
159(5):491-498, 2004. [PMID:14977645]
198. Lohmander LS, Felson D. Can we identify a ‘high risk’ patient profile to determine who
will experience rapid progression of osteoarthritis? Osteoarthritis Cart 12 (Suppl A):S4952, 2004. [PMID:14698642]
16
199. Felson DT, Neogi T. Osteoarthritis: Is it a disease of cartilage or bone? Arthritis Rheum
50(2):341-344, 2004. [PMID:14872473]
200. Zhang Y, Hunter DJ, Nevitt MC, Xu L, Niu J, Liu L, Yu W, Aliabadi P, Felson DT.
Squatting increases the prevalence of radiographic tibiofemoral osteoarthritis: The Beijing
Osteoarthritis Study. Arthritis Rheum 50(4): 1187-1192, 2004. [PMID:15077301]
201. Karasik D, Hannan MT, Cupples LA, Felson DT, Kiel DP. Genetic and environmental
contributions to biological aging: the Framingham Study. J Gerontol (biological sciences)
59A: 218-226, 2004. [PMID:15031305]
202. Hunter DJ, Zhang Y, Nevitt MC, Xu L, Niu J, Liu L, Yu W, Aliabadi P, Felson DT:
Chopstick Arthropathy. The Beijing Osteoarthritis Study. Arthritis Rheum 50: 1495-1500,
2004. [PMID:15146419]
203. Fraenkel L, Bogardus S, Concato J, Felson D, Wittink D: Patient preferences for treatment of
rheumatoid arthritis. Ann Rheum Dis 63: 1372-1378, 2004. [PMID:15020312]
204. Baker KR, Xu L, Zhang Y, Nevitt M, Aliabadi P, Yu W, Felson DT: Quadriceps weakness
and its relation to tibiofemoral and patellofemoral knee osteoarthritis. Arthritis Rheum
50(6):1815-1821, 2004. [PMID:15188358]
205. Felson DT: Obesity and vocational and avocational overload of the joint as risk factors for
osteoarthritis. J Rheumatol 31(suppl 70): 2-5, 2004. [PMID:15132347]
206. Felson DT: Whither ACR20? J Rheumatol 31(5)835-83, 2004. [PMID:15124237]
207. Carbone LD, Nevitt MC, Wildy K, Barrow KD, Harris F, Felson D, Peterfy C, Visser M,
Harris TB, Wang BWE ,Kritchevsky SB for the Health ABC Study. The relationship of
antiresorptive drug use to structural findings and symptoms of knee osteoarthritis. Arthritis
Rheum 50: 3516-3525, 2004. [PMID:15529367]
208. Hunter DJ, Demissie S, Cupples LA, Aliabadi P, Felson DT. A genome scan for joint
specific hand osteoarthritis susceptibility: the Framingham Study. Arthritis Rheum 50:
2489-2496, 2004. [PMID:15334462]
209. Felson DT, Goggins J, Niu J, Zhang Y, Hunter DJ. The effect of body weight on
progression of knee osteoarthritis is dependent on alignment. Arthritis Rheum 50: 39043909, 2004. [PMID:15593215]
210. Conaghan PG, Felson DT. Structural associations of osteoarthritis pain: lessons from
magnetic resonance imaging. Novartis Foundation Symposium 260:191-201, 2004.
[PMID:15283451]
211. Felson DT, Glantz L: A surplus of positive trials: weighing biases and reconsidering
equipoise. Arthritis Res Ther 6(3):R250-5, 2004. [PMID:15142261]
212. Badlissi F, Dunn JE, Link CL, Keysor JJ, McKinlay JB, Felson DT. Foot musculoskeletal
disorders, pain, and foot-related functional limitation in older persons. J Am Geriatr Soc
53(6):1029-33, 2005. [PMID:15935029]
213. Tubach F, Ravaud P, Baron G, Falissard B, Logeart I, Bellamy N, Bombardier C, Felson DT,
Hochberg MC, van der Heijde D, Dougados M. Evaluation of clinically relevant states in
patient-reported outcomes in knee and hip osteoarthritis: The Patient Acceptable Symptom
State. Ann Rheum Dis 64: 34-37, 2005. [PMID:15130902]
214. Tubach F, Ravaud P, Baron G, Falissard B, Logeart I, Bellamy N, Bombardier C, Felson DT,
Hochberg MC, van der Heijde D, Dougados M. Evaluation of clinically relevant states in
patient-reported outcomes in knee and hip osteoarthritis: The minimal clinically important
improvement. Ann Rheum Dis 64: 29-33, 2005. [PMID:15208174]
17
215. Tan ZS, Seshadri S, Beiser A, Zhang Y, Felson D, Hannan MT, Au R, Wolf PA, Kiel DP.
Bone mineral density and the risk of Alzheimer’s Disease. Arch Neurol 62: 107-111, 2005.
[PMID:15642856]
216. Hill CL, Seo GS, Gale D, Totterman, Gale ME, Felson DT. Cruciate ligament integrity in
osteoarthritis of the knee. Arthritis Rheum 52: 794-799, 2005. [PMID:15751064]
217. Felson DT, Gale DR, Gale ME, Niu J, Hunter DJ, Goggins J, LaValley MP. Osteophytes
and progression of knee osteoarthritis. Rheumatology 44:100-104, 2005. [PMID:15381791]
218. Goggins J, Baker KR, Felson DT: What WOMAC pain score should make a person
eligible for a trial in knee osteoarthritis? J Rheumatol 32: 540-542, 2005.
[PMID:15742450]
219. Felson DT: Risk factors for osteoarthritis: understanding joint vulnerability. Clin Orthop Rel
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220. Edmond SL, Kiel DP, Samelson EJ, Kelly-Hayes M, Felson DT: Vertebral deformity, back
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Osteoporosis Int 16: 1086-1095, 2005. [PMID:15726295]
221. Roemer FW, Guermazi A, Lynch JA, Peterfy CG, Nevitt MC, Webb N, Li J, Mohr A,
Genant HK, Felson DT: Short tau inversion recovery and proton density-weighted fat
suppressed sequences for the evaluation of osteoarthritis of the knee with a 1.0 T dedicated
extremity MRI: development of a time-efficient sequence protocol. Eur Radiol 15: 978987, 2005. [PMID:15633060]
222. Badlissi, F., Dunn JE, Link CL, Keysor JJ, McKinlay JB, Felson DT, Foot musculoskeletal
disorders, pain, and foot-related functional limitation in older persons. J Am Geriatr Soc
53(6): p. 1029-33, 2005.
223. Suter LS, Murabito JM, Felson DT, Fraenkel L: The incidence and natural history of
Raynaud’s phenomenon in the community. Arthritis Rheum 52:1259-1263, 2005.
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224. Hunter, DJ, Niu J, Zhang Y, Nevitt MC, Xu L, Lui LY, Yu W, Aliabadi P, Buchanan TS,
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Study. Arthritis Rheum 52: 1418-1423, 2005. [PMID:15880346]
225. Felson DT, Cummings SR: Aromatase inhibitors and the syndrome of arthralgias with
estrogen deprivation. Arthritis Rheum 52: 2594-2598, 2005. [PMID:16142740]
226. Keysor JJ, Link CL, Dunn JE, Badlissi F, Felson DT: Are foot disorders associated with
functional limitation and disability among community dwelling older adults? J Aging
Health 17: 734-752, 2005. [PMID:16377770]
227. Leveille S, Zhang Y, McMullen W, Kelly-Hayes M, Felson D: Sex differences in
musculoskeletal pain in older adults. Pain 116: 332-338, 2005. [PMID:15982814]
228. Amin S, LaValley MP, Guermazi A, Grigorian M, Hunter DJ, Clancy M, Niu J, Gale DR,
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narrowing in knee osteoarthritis. Arthritis Rheum 52: 3152-3159, 2005. [PMID:16200595]
229. Hunter DJ, Zhang Y, Niu J, Tu X, Amin S, Goggins J, LaValley M, Guermazi A, Gale D,
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Boston Osteoarthritis Knee Study. J Rheumatol 32: 2192-2199, 2005. [PMID:16265702]
230. Lo GH, Hunter DJ, Zhang Y, McLennan CE, LaValley MP, Kiel DP, McLean RR, Genant
HK, Guermazi A, Felson DT: Bone marrow lesions in the knee are associated with
increased local bone density. Arthritis Rheum 52: 2814-2821, 2005. [PMID:16145676]
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231. Hunter DJ, Zhang Y, Sokolove J, Niu J, Aliabadi P, Felson DT: Trapeziometacarpal
subluxation predisposes to incident trapeziometacarpal osteoarthritis: the Framingham
Study. Osteoarthritis Cart 13: 953-957, 2005. [PMID:16139531]
232. LaValley MP, McLaughlin S, Goggins J, Gale D, Nevitt MC, Felson DT: The lateral x-ray
for assessment of the tibiofemoral joint space in knee osteoarthritis: its reliability,
sensitivity to change and longitudinal validity. Arthritis Rheum 52: 3542-3547, 2005.
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233. Merkel PA, Seo P, Aries P, Neogi T, Villa-forte A, Boers M, Cuthbertson D, Felson DT et
al: Current status of outcome measures in vasculitis: focus on Wegener’s granulomatosis
and microscopic polyangiitis. Report from OMERACT 7. J Rheumatol 32: 2488-2495,
2005. [PMID:16331794]
234. Felson DT: Relation of obesity and vocational and avocational risk factors to osteoarthritis:
an update. J Rheumatol 32: 1133-1134, 2005. [PMID:15977343]
235. Bischoff-Ferrari H, Zhang Y, Kiel D, Felson D: Positive association between serum 25hydroxyvitamin D level and bone density in osteoarthritis. Arthritis Rheum 53: 821-826,
2005. [PMID:16342101]
236. Karasik D, Kiel DP, Kiely DK, Cupples LA, Wilson PWF, O’Donnell CJ, Felson DT:
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Framingham Study. Calc Tissue Int 78:1-8, 2006. [PMID:16397734]
237. Amin S, Zhang Y, Felson DT, Sawin CT, Hannan MT, Wilson PWF, Kiel DP: Estradiol,
testosterone and the risk of hip fracture in elderly men from the Framingham Study. Am J
Med 119: 426-433, 2006. [PMID:16651055]
238. Hunter DJ, Zhang Y, Niu JB, Goggins J, Amin S, LaValley MP, Guermazi A, Genant H,
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longitudinal MRI study in knee osteoarthritis. Arthritis Rheum 54: 1529-1535, 2006.
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240. Hunter DJ, Zhang Y, Niu JB, Tu X, Amin S, Clancy M, Guermazi A, Grigorian M, Gale D,
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osteoarthritis. Arthritis Rheum 54: 795-801, 2006. [PMID:16508930]
241. Felson DT: Osteoarthritis of the knee. N Engl J Med 354: 841-848, 2006.
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242. Neogi T, Booth SL, Zhang YQ, Jacques PF, Terkeltaub R, Aliabadi P, Felson DT: Low
vitamin K status is associated with knee osteoarthritis in the hand and knee. Arthritis
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243. Hunter DJ, Felson DT: Osteoarthritis. BMJ 332: 639-642, 2006. [PMID:16543327]
244. Singh JA, Solomon DH, Dougados M, Felson DT, Hawker G, Katz P, Paulus H, Wallace
C: Development of classification and response criteria for rheumatic diseases. Arthritis
Rheum (Arthritis Care Res) 55: 348-352, 2006. [PMID:16739201]
245. Wells GA, Boers M, Shea B….Felson DT: Minimal disease activity for rheumatoid
arthritis: a preliminary definition. J Rheumatol 32: 2016-2024, 2006. [PMID:16206362]
246. Lo GH, Zhang YQ, Aliabadi P, McLennan C, Niu JB, Kiel DP, McLean R, Hogan M,
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247. Hunter DJ, Zhang YQ, LaValley M, Niu JB, Amin S, Guermazi A, Grigorian M, Genant H,
Gale D, Felson DT: Change in joint space width: hyaline articular cartilage loss or
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248. Conaghan, PG, Tennant A, Peterfy CG, Woodworth T, Stevens R, Guermazi A, Genant H,
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system for osteoarthritis of the knee using Rasch analysis. Osteoarthritis Cart 14 Suppl
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249. Zhang Y, Chaisson CE, McAlindon T, Woods R, Hunter DJ, Niu JB, Neogi T, Felson DT :
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60:50-55, 2007. [PMID:17161754]
250. Neogi T, Nevitt M, Niu J, LaValley MP, Hunter DJ, Terkeltaub R, Carbone L, Chen H,
Harris T, Kwoh K, Guermazi A, Felson DT. Lack of association between
chondrocalcinosis and increased risk of cartilage loss in knees with osteoarthritis: results of
two prospective longitudinal magnetic resonance imaging studies. Arthritis Rheum
54:1822-1828, 2006. [PMID:16729275]
251. Sengupta M, Zhang YQ, Niu JB, Guermazi A, Grigorian M, Gale D, Felson DT, Hunter
DJ: High signal in knee osteophytes is not associated with knee pain. Osteoarthritis Cart
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252. Samelson EJ, Hannan MT, Zhang Y, Genant HK, Felson DT, Kiel DP : Incidence and risk
factors for vertebral fracture in women and men: 25 year follow-up results from the
population-based Framingham Study, J Bone Min Res 21:1207-1214, 2006.
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253. Conaghan PG, Felson D, Gold G, et al. MRI and noncartilaginous structure in knee
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254. Eckstein F, Ateshian G, Burghart R…Felson D: Proposal for a nomenclature for magnetic
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255. Felson DT, Niu JB, Clancy M, Sack B, Aliabadi P, Zhang Y: The effect of recreational
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weights: the Framingham Study. Arthritis Care Res 57: 6-12, 2007. [PMID:17266077]
256. Zhang YQ, Terkeltaub R, Nevitt M, Xu L, Neogi T, Aliabadi P, Niu JB, Felson DT: Lower
prevalence of chondrocalcinosis in Chinese subjects in Beijing than in Whites in the United
States: the Beijing Osteoarthritis Study. Arthritis Rheum, 54: 3508-3512, 2006.
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257. Bauer DC, Hunter DJ, Abramson SB, Attur M, Corr M, Felson D …Kraus VB:
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258. Suter LG, Murabito JM, Felson DT, Fraenkel L: Smoking, alcohol consumption and
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259. Felson DT, Furst DE, Boers M: Rationale and strategies for reevaluating the ACR20. J
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260. Amin S, Niu JB, Guermazi A, Grigoryan M, Hunter DJ, Clancy M, LaValley MP, Genant
HK, Felson DT: Cigarette smoking and the risk of cartilage loss and knee pain in men with
knee osteoarthritis. Ann Rheum Dis 66: 18-22, 2007. [PMID:17158140]
261. Felson DT, Niu JB, Clancy M, Aliabadi P, Sack B, Guermazi A et al: Low levels of
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262. Tubach F, Ravaud P, Beaton D, Boers M, Bombardier C, Felson DT, van der Heijde D,
Wells G, Dougados M. Minimal clinically important improvement and patient acceptable
symptom state for subjective outcome measures in rheumatic disorders. J Rheumatol 34:
1188-1193, 2007. [PMID:17477485]
263. Kapoor A, Page S, LaValley M, Gale DR, Felson DT: MRI for diagnosing foot
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264. Felson DT, Kim Y-J: The futility of current approaches to chondroprotection. Arthritis
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265. Hunter DJ, Niu JB, Felson DT et al: Knee alignment does not predict incident
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266. Nevitt MC, Peterfy C, Guermazi A, Felson DT, Duryea J, Woodworth T, Chen H, Kwoh
K, Harris TB: Longitudinal performance evaluation and validation of fixed flexion
radiography of the knee for detection of joint space loss. Arthritis Rheum 56: 1512-1520,
2007. [PMID:17469126]
267. Baker KR, Goggins J, Hunter DJ, Xie H, Felson DT: A randomized cross-over trial of a
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268. Hunter DJ, LaValley M, Li J…. Felson DT: Urinary pentosidine does not predict cartilage
loss among subjects with symptomatic knee OA: the BOKS Study. Osteoarthritis Cart 15:
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269. Felson D, Alteaha D, Anderson J…Xie H: American College of Rheumatology Committee
to Reevaluate Improvement Criteria. A proposed revision to the ACR20: the hybrid
measure of the American College of Rheumatology response. Arthritis Rheum 57(2):193202, 2007.
270. Johnson S, Goek O-N, Singh-Grewal D, Vlad S, Feldman B, Felson DT, Hawker G, Singh
J, Solomon D: Classification criteria in rheumatic diseases. A review of methodologic
properties. Arthritis Care Res, Arthritis Rheum 57(7): 1119-33, 2007. [PMID:17907227]
271. Kalichman L, Zhang YQ, Niu JB, Goggins J, Gale D, Felson DT, Hunter DJ: The
association between patellar alignment on magnetic resonance imaging and radiographic
manifestations of knee osteoarthritis. Arthritis Res Ther 9(2): R26, 2007.
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272. Felson DT: Chondroitin for pain in osteoarthritis. Ann Intern Med 146: 611-612, 2007.
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273. Vlad S, LaValley MP, McAlindon TE, Felson DT: Glucosamine for pain in osteoarthritis:
why do trial results differ? Arthritis Rheum 56(7): 2267-77, 2007. [PMID:17599746]
274. Kalichman L, Zhu Y, Zhang Y, Niu J, Gale D, Felson DT, Hunter D: The association
between patella alignment and knee pain and function: an MRI study in persons with
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275. Hunter DJ, Zhang YQ, Niu JB, Felson DT, Nevitt M: Patella malalignment, pain and
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2007. [PMID:17502158]
276. Segal NA, Felson DT, Torner JC, Zhu Y, Curtis JR, Niu JB, Nevitt MC Greater
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Rehab 88:988-992, 2007. [PMID:17678660]
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277. Felson DT, Niu, J, Guermazi, A, Roemer, F, Aliabadi, P, Clancy, M, Torner, J, Lewis, CE,
and Nevitt, MC: Correlation of the development of knee pain with enlarging bone marrow
lesions on magnetic resonance imaging. Arthritis Rheum 56(9):2986-2992, 2007.
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278. Hill CL, Hunter DJ, Niu J, Clancy M, Guermazi A, Genant H, Gale D, Grainger A,
Conaghan P, Felson DT. Synovitis detected on magnetic resonance imaging and its relation
to pain and cartilage loss in knee osteoarthritis. Ann Rheum Dis 66:1599-1603, 2007.
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279. Gross KD, Niu J, Zhang YQ, Felson DT, McLennan C, Hannan MT, Holt KG, Hunter DJ.
Varus foot alignment and hip conditions in older adults. Arthritis Rheum. 56(9):2993-8,
2007. [PMID:17763430]
280. Englund M...Felson DT. Effect of meniscal damage on the development of frequent knee
pain, aching, or stiffness. Arthritis Rheum 56(12):4048-4054, 2007. [PMID:18050201]
281. Felson DT, Niu, J, McClennan, C, Sack, B, Aliabadi, P, Hunter, DJ, Guermazi, A, and
Englund, M: Knee buckling: prevalence, risk factors, and associated limitations in function.
Ann Intern Med 147(8): 534-540, 2007. [PMID:17938391]
282. Hunter DJ, Li J, LaValley M, Bauer DC, Nevitt MC … Felson DT: Cartilage markers and
their association with cartilage loss on magnetic resonance imaging in knee osteoarthritis:
the Boston Osteoarthritis Knee Study. Arthritis Res Ther 9(5): R108, 2007.
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283. Kalichman L, Zhang Y, Niu J, Goggins J, Gale D, Felson DT, Hunter, D: The association
between patellar alignment and patellofemoral joint osteoarthritis features--an MRI study.
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284. Hernández-Molina G, Neogi T, Hunter DJ, Niu J, Guermazi A, Roemer FW, McLennan
CE, Reichenbach S, Felson DT. The association of bone attrition with knee pain and other
MRI features of osteoarthritis. Ann Rheum Dis 67:43-47, 2008. [PMID:19623678]
285. Hernandez-Molina G, Guermazi A, Niu J, Gale D, Goggins J, Amin S, Felson DT: Central
bone marrow lesions in symptomatic knee osteoarthritis and their relationship to anterior
cruciate ligament tears and cartilage loss. Arthritis Rheum 58: 130-136. 2008.
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286. Neogi T, Felson DT. Composite vs. Individual Measures of Disease Activity in
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287. Felson DT: Comparing the prevalence of rheumatic diseases in China with the rest of the
world. Arthritis Res Ther 10 (1): 106, 2008. [PMID:18341701]
288. Helmick CG, Felson DT, Lawrence RC, et al. Estimates of the prevalence of arthritis and
other rheumatic conditions in the U.S. Part I. Arthritis Rheum 58: 15-25, 2008.
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289. Lawrence RC, Felson DT, Helmick CG, et al. Estimates of the prevalence of arthritis and
other rheumatic conditions in the U.S. Part II. Arthritis Rheum 58: 26-35, 2008.
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290. Harvey WF, Niu J, Zhang Y, McCree PI, Felson DT, Nevitt MC, Xu L, Aliabadi P, Hunter
DJ: Knee alignment differences between Chinese and Caucasians subjects without
osteoarthritis. Ann Rheum Dis, 2008.
291. Vlad SC, Miller DR, Kowall NW, Felson DT. Protective effects of NSAIDs on the
development of Alzheimer disease. Neurology. 2008 May 6; 70(19):1672-7.
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292. Zhang B, LaValley MP, Felson DT: The sensitivity to change for lower disease activity is
greater than for higher disease activity in rheumatoid arthritis trials, Ann Rheum Dis.
68:1255-1259, 2009 [PMID:19958618]. [PMCID:2758235]
293. Felson DT, Siegel J, Zhang B: Trials in Rheumatoid Arthritis: Choosing the right outcome
measure when minimal disease is achievable. Ann Rheum Dis, 67: 580-583, 2008.
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294. Roemer FW, Guermazi A, Javaid MK, Lynch JA, Niu J, Zhang Y, Felson DT, Lewis CE,
Torner J, Nevitt MC. Change in MRI-Detected subchondral bone marrow lesions is
associated with cartilage loss - the MOST study A longitudinal multicenter study of knee
osteoarthritis. Ann Rheum Dis. 68:1461-1465, 2009. [PMID:18829615]
295. Felson DT. Glucosamine sulfate might have no effect on pain or structural changes
associated with osteoarthritis. Nat Clin Pract Rheumatol. Oct 4(10): 518-9, 2008
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296. Karonitsch T, Aletaha D, Boers M, Bombardieri S, Combe B, Dougados M, Emery P,
Felson D, Gomez-Reino J, Keystone E, Kvien TK, Martin-Mola E, Matucci-Cerinic M,
Richards P, van Riel P, Siegel J, Smolen JS, Sokka T, van der Heijde D, van Vollenhoven
R, Ward M, Wells G, Zink A, Landewe R. Methods of deriving EULAR/ACR
recommendations on reporting disease activity in clinical trials of patients with rheumatoid
arthritis. Ann Rheum Dis. Oct; 67(10):1365-73. 2008 [PMID:18791056]
297. Neogi T, Nevitt MC, Ensrud KE, Bauer D, Felson DT: The effect of alendronate on
progression of spinal osteophytes and disc space narrowing. Ann Rheum Dis. Oct;
67(10):1427-30. 2008 [PMID:18276744]
298. Aletaha D, Landewe R, Karonitsch T, Bathon J, Boers M, Bombardier C, Bombardieri S,
Choi H, Combe B, Dougados M, Emery P, Gomez-Reino J, Keystone E, Koch G, Kvien
TK, Martin-Mola E, Matucci-Cerinic M, Michaud K, O'Dell J, Paulus H, Pincus T,
Richards P, Simon L, Siegel J, Smolen JS, Sokka T, Strand V, Tugwell P, van der Heijde
D, van Riel P, Vlad S, van Vollenhoven R, Ward M, Weinblatt M, Wells G, White B,
Wolfe F, Zhang B, Zink A, Felson D; EULAR; ACR. Reporting disease activity in clinical
trials of patients with rheumatoid arthritis: EULAR/ACR collaborative recommendations.
Arthritis Rheum. Oct 15; 67:1360-1364. 2008 [PMID:18821648]
299. Amin S, Guermazi A, LaValley MP, Niu J, Clancy M, Hunter DJ, Grigoryan M, and Felson
DT: Complete anterior cruciate ligament tear and the risk for cartilage loss and progression
of symptoms in men and women with knee osteoarthritis. Osteoarthritis Cart 16: 897-902,
2008. [PMID:18203629]
300. Hanchate AD, Zhang Y, Felson DT, Ash AS: Exploring the determinants of racial and
ethnic disparities in total knee arthroplasty: health insurance, income and assets. Medical
Care 46: 481-488, 2008. [PMID:18438196] [PMCID:2758246]
301. Neogi T, Zhang B, Felson DT: The relative responsiveness of physician/assessor-derived
and patient-derived core set measures in rheumatoid arthritis trials. J Rheumatol, 35: 75762, 2008. [PMID:18412313] [PMCID:2748769]
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302. Reichenbach S, Guermazi A, Niu J…Felson DT: Prevalence of bone attrition on knee
radiographs and MRI in a community-based cohort. Osteoarthritis Cart, 16: 1005-10, 2008.
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303. Hunter DJ, Niu J, Zhang Y, Lavalley M, McClennan CE, Hudelmaier M, Eckstein F,
Felson DT: Premorbid knee OA is not characterized by diffuse cartilage thinness: The
Framingham Study. Ann Rheum Dis, 67: 1545-9, 2008. [PMID:18218668]
304. Amin S, Goggins J, Niu J, … Felson DT: Occupation related squatting, kneeling and heavy
lifting and the knee joint: an MRI based study in men. J Rheumatol 35: 1645-1649, 2008.
[PMID:18597397] [PMCID:2758236]
305. Hernandez-Molina G, Reichenbach S, Zhang B, LaValley M, Felson DT: The effect of
therapeutic exercise for hip osteoarthritis pain: results of a meta-analysis. Arthritis Rheum,
59:1221-8, 2008. [PMID:18759315] [PMCID:2758534]
306. Hunter DJ, Lavalley M, Li J, Bauer DC, Nevitt M, DeGroot J, Poole R, Eyre D, Guermazi
A, Gale D, Totterman S, Felson DT. Biochemical markers of bone turnover and their
association with bone marrow lesions. Arthritis Res Ther.;10 (4): R102. 2008
[PMID:18218668]
307. Felson DT, Nevitt MC, Yang M, Clancy M, Niu J, Torner JC et al: A new approach yields
high rates of x-ray progression in knee osteoarthritis. J Rheumatol 35: 2047-2054, 2008.
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308. Segal NA, Harvey W, Felson DT, Yang M, Torner JC, Curtis JR, et al: Leg length
inequality is not associated with greater trochanteric pain syndrome. Arthritis Res Ther 10:
R62, 2008 (doi: 10.1186/ar2433). [PMID:18510741]
309. Englund M, Guermazi A, Gale D….Felson DT: Incidental meniscal findings on knee MRI
in middle aged and elderly persons in the United States. N Engl J Med, 359: 1108-1115,
2008. [PMID:18784100] [PMCID:2897006]
310. Segal NA, Torner JC, Yang M, Curtis JR, Felson DT, Nevitt MC; Multicenter
Osteoarthritis Study Group. Muscle mass is more strongly related to hip bone mineral
density than is quadriceps strength or lower activity level in adults over age 50 year. J Clin
Densitom. Oct-Dec;11(4):503-10. 2008 [PMID:18456530]
311. Bingham JT, Papannagari R, VandeVelde SK, Gross C, Gill TJ, Felson DT, Rubash HE, Li
G: In vivo cartilage contact deformation in the healthy human tibiofemoral joint.
Rheumatol, 47:1622-1627, 2008. [PMID:18775967]
312. Harvey WF, Niu J, Zhang Y, McCree PI, Felson DT, Nevitt M, Xu L, Aliabadi P, Hunter
DJ. Knee alignment differences between Chinese and Caucasian subjects without
osteoarthritis. Ann Rheum Dis. Nov; 67 (11): 1524-8. 2008 [PMID:18230630]
313. Neogi T, Felson DT, Sarno R, Booth SL. Vitamin K in hand osteoarthritis: results from a
randomised clinical trial. Ann Rheum Dis. Nov; 67 (11): 1570-3. 2008 [PMID:18625626]
314. Amin S, Baker K, Niu J ….Felson DT: Quadriceps strength and the risk for cartilage loss
and symptom progression in knee osteoarthritis. Arthritis Rheum. Jan;60 (1):189-98. 2009
[PMID:19116936]
315. Birrell F, Felson D. The age of osteoarthritis. Age Ageing. Jan; 38:2-3. 2009
[PMID:19054784]
316. Roemer FW, Zhang Y, Niu J, Lynch JA, Crema MD, Marra MD, Nevitt MC, Felson DT,
Hughes LB, El-Khoury GY, Englund M, Guermazi A: Tibiofemoral joint osteoarthritis:
risk factors for MR-depicted fast cartilage loss over a 30-month period in the multicenter
osteoarthritis study. Radiology 252:772-780, 2009. [PM:19635831]
24
317. Segal NA, Torner JC, Felson DT, Niu J, Sharma L, Lewis CE, Nevitt M: Knee extensor
strength does not protect against incident knee symptoms at 30 months in the multicenter
knee osteoarthritis (MOST) cohort. PM R 1:459-465, 2009. [PM:19627933]
318. Nevitt MC, Zhang Y, Javaid MK….Felson DT: High systemic bone density, fractures and
the risk of incident and progressive radiographic knee OA: the MOST Study. Ann Rheum
Dis. 69:163-168, 2010. [PMID:19147619]
319. Neogi T, Ellison CR, Hunt S, Terkeltaub R, Felson DT, Zhang Y: Serum uric acid is
associated with carotid plaques: the NHLBI Family Heart Study, J Rheumatol. Feb; 36 (2):
378-84. 2009 [PMID:19012359] [PMCID:2731484]
320. Reichenbach S, Yang M, Eckstein F…Felson DT: Do cartilage volume or thickness
distinguish knees with and without mild radiographic osteoarthritis? The Framingham
Study. Ann Rheum Dis. 69:143-149, 2010. [PMID:19193659] [PMCID:2794983]
321. Jette AM, McDonough CM, Haley SM, Ni P, Olarsch S, Latham N, Hambleton RK, Felson
D et al: A computer-adaptive disability instrument for lower extremity osteoarthritis
research demonstrated promising breadth, precision and reliability. J Clin Epidemiol, J Clin
Epidemiol. 62:807-815, 2009. [PMID:19210652]
322. Felson DT, Nevitt MC: Blinding images to sequence; evidence from other diseases.
Osteoarthritis Cartilage. Mar; 17(3): 281-3. 2009 [PMID:18977156]
323. Englund M, Guermazi A, Roemer FW, Aliabadi P, Yang M, Lewis CE, Torner J, Nevitt
MC, Sack B, Felson DT. Meniscal tear in knees without surgery and the development of
radiographic osteoarthritis among middle-aged and elderly persons: The Multicenter
Osteoarthritis Study. Arthritis Rheum. Mar; 60 (3): 831-9. 2009 [PMID:19248082]
[PMCID:2758243]
324. Niu J, Zhang YQ, Torner J, ….Felson DT: Is obesity a risk factor for progressive
radiographic knee osteoarthritis? The MOST Study, Arthritis Rheum. Mar 15; 61(3): 32935. 2009 [PMID:19248122]
325. Kang X, Fransen M, Zhang YQ, Li H, Ke Y, Lu M, Su S, Song X, Guo Y, Chen J, Niu J,
Felson D, Lin J: High prevalence of knee osteoarthritis in a rural Chinese population: the
Wuchuan Osteoarthritis Study, Arthritis Rheum, May 15; 61(5):641-7. 2009
[PMID:19405001]
326. Felson DT, Lohmander LS: Whither osteoarthritis biomarkers? Osteoarthritis Cart 17: 419422, 2009. [PMID:19248750] [PMCID:2758244]
327. Felson DT. Developments in the clinical understanding of osteoarthritis. Arthritis Res
Ther.;11(1):203. 2009 [PMID:19232065]
328. Wolfe F, Boers M, Felson D, Michaud K, Wells GA. Remission in rheumatoid arthritis:
physician and patient perspectives. J Rheumatol. May; 36 (5):930-3. 2009
[PMID:19332634]
329. van Tuyl LH, Vlad SC, Felson DT, Wells G, Boers M. Defining remission in rheumatoid
arthritis: Results of an initial American College of Rheumatology/European League against
Rheumatism consensus conference. Arthritis Rheum. May 15; 61(5):704-10. 2009
[PMID:19405006]
330. Felson DT, Cooke TD, Niu J, Goggins J, Choi J, Yu J, Nevitt MC; The OAI Investigators
Group. Can anatomic alignment measured from a knee radiograph substitute for
mechanical alignment from full limb films? Osteoarthritis Cart. 17: 1448-1452. 2009
[PMID:19505430] [PMCID:2763977]
25
331. Roemer FW, Guermazi A, Hunter DJ, Niu J, Zhang Y, Englund M, Javaid MK, Lynch JA,
Mohr A, Torner J, Lewis CE, Nevitt MC, Felson DT. The association of meniscal damage
with joint effusion in persons without radiographic osteoarthritis: the Framingham and
MOST osteoarthritis studies. Osteoarthritis Cartilage. Jun; 17 (6):748-53. 2009
[PMID:19008123]
332. Fayfman M, Niu J, Zhang YQ, Felson DT, Sack B, Aliabadi P, Selhub J, Hunter DJ. The
relation of plasma homocysteine to radiographic knee osteoarthritis. Osteoarthritis
Cartilage. Jun; 17(6):766-71. 2009 [PMID:19073367] [PMCID:2758241]
333. Segal NA, Anderson DD, Iyer KS, Baker J, Torner JC, Lynch JA, Felson DT, Lewis CE,
Brown TD. Baseline articular contact stress levels predict incident symptomatic knee
osteoarthritis development in the MOST cohort. J Orthopedic Res,;27:1562-1568. 2009
[PMID:19533741]
334. Vlad SC, Felson DT, Miller DR. Can healthcare databases be used to identify incident
cases of osteonecrosis? Arthritis Res Ther. Jun 17;11(3): R89. 2009 [PMID:19534782]
335. Felson DT, Gross KD, Nevitt MC, et al: The effects of joint position sense of the
development and progression of pain and structural damage in knee osteoarthritis. Arthritis
Rheum 61:1070-1076, 2009. [PMID:19644911]
336. Neogi T, Felson DT, Niu J, et al: Cartilage loss occurs in the same subregions as
subchondral bone attrition: a within-knee subregion-matched approach from The MOST
Study, Arthritis Rheum (Arthritis Care Res), 61: 1539-1544, 2009. [PMID:19877101]
337. Neogi T, Felson D, Niu J, Nevitt M, Lewis CE, Aliabadi P, Sack B, Torner J, Bradley L,
Zhang YQ. Association between radiographic features of knee osteoarthritis and pain:
results from two cohort studies. BMJ 339: b2844, 2009. [PMID:19700505]
338. Segal NA, Torner JC, Felson D, et al: Effect of thigh strength on incident radiographic and
symptomatic knee osteoarthritis in a longitudinal cohort. Arthritis Rheum (Arthritis Care
Res): 61: 1210-1217, 2009. [PMID:19714608]
339. Jette AM, McDonough CM, Ni P, Haley SM, Hambleton RK, Olarsch S, Hunter D, Kim Y,
Felson D. A functional difficulty and functional pain instrument for hip and knee
osteoarthritis. Arthritis Res Ther,11:R107, 2009. [PMID:19589168]
340. Wise BL, Demissie S, Cupples A, Felson DT, et al. The relationship of estrogen receptor
alpha and beta genes with osteoarthritis of the hand. J Rheumatol 36:2772-79, 2009.
[PMID:19884274]
341. Kerkhof HJM, Lories RJ, Meulenbelt I, …Felson DT, et al. A genome-wide association
study identifies a locus on chromosome 7q22 to influence susceptibility for osteoarthritis.
Arthritis Rheum;62(2):499-510, 2010. [PMID:20112360]
342. Neogi T, Nevitt M, Niu J, Sharma L, Roemer F, Guermazi A, Lewis CE, Torner J, Javaid
K, Felson D. Subchondral bone attrition may be a reflection of compartment-specific
mechanical load: The MOST Study. Ann Rheum Dis. 69:841-844, 2010.
doi:10.1136/ard.2009.110114. [PMID:19762366] [PMCID:2891513]
343. Keysor JJ. Jette AM, LaValley MP, Lewis CE, Torner JC, Nevitt MC, Felson DT.
Community environmental factors are associated with disability in older adults with
functional limitations: the MOST Study. J Gerontol Med Sciences 65:393-399, 2010.
[PMID:19995830]
344. Van Tuyl L, Felson DT, Wells G, et al: Systematic review: Evidence for predictive validity
of remission on long term outcome in rheumatoid arthritis. Arthritis Care Res 62: 108-117,
2010. [PMID:21091498]
26
345. Harvey WF, Yang M, Cooke TDV...Felson DT. Association of leg-length inequality with
knee osteoarthritis: a cohort study. Ann Intern Med 152(5):287-95, 2010.
[PMID:20194234]
346. Felson DT. Identifying different osteoarthritis phenotypes through epidemiology.
Osteoarthritis Cartilage;18(5):601-4, 2010. [PMID:20175975]
347. White DK, Keysor JJ, LaValley MP...Felson DT. Clinically important improvement in
function is common in people with or at high risk of knee OA: the MOST Study, J
Rheumatol, 37(6):1244-51, 2010. [PMID:20395640]
348. Baker K, Grainger A, Niu J,....Felson DT. The relation of synovitis to knee pain using
contrast enhanced MRIs. Ann Rheum Dis 69:1779-1783, 2010. [PMID:20472593]
349. Roemer FW, Neogi T, Nevitt MC, Felson DT, et al. Subchondral bone marrow lesions are
highly associated with, and predict subchondral bone attrition longitudinally: the MOST
Study. Osteoarthritis Cart 18: 47-53, 2010. [PMID:19769930]
350. Javaid MK, Lynch JA, Tolstykh I, Guermazi A, Roemer F, Aliabadi P, McCullough C,
Curtis J, Felson D, et al. Pre-radiographic MRI findings are associated with onset of knee
symptoms: the MOST Study, Osteoarthritis Cart 18: 323-28, 2010. [PMID:19919856]
351. Segal NA, Glass NA, Torner J, Yang M, Felson DT, et al. Quadriceps weakness predicts
risk for knee joint space narrowing in women in the MOST cohort. Osteoarthritis Cart;
18(6):769-75, 2010. [PMID:20188686]
352. Englund M, Guermazi A, Roemer FW…Felson DT. Meniscal pathology on MRI increases
the risk for both incident and enlarging subchondral bone marrow lesions of the knee: the
MOST Study, Ann Rheum Dis 69:1796-1802, 2010. [PMID:20421344]
353. Sled EA, Sheehy LM, Felson DT, Costigan PA, Lam M, Cooke TDV. Reliability of lower
limb alignment measures using an established landmark-based method with a customized
computer software program. Rheumatol Int 31:71-77, 2011. [PMID:19882339]
354. Englund M, Joud A, Geborek P, Felson DT, Jacobsson LT, Petersson IF. Prevalence and
incidence of rheumatoid arthritis in southern Sweden 2008 and their relation to prescribed
biologics. Rheumatol 49:1563-1569, 2010. [PMID:20444855]
355. Stefanik J, Zhu Y, Zumwalt A, Gross KD, Clancy M, Lynch J...Felson DT. The association
between patella alta and the prevalence and worsening of structural features of
patellofemoral joint osteoarthritis: the multicenter osteoarthritis study. Arthritis Care Res,
62:1258-1265, 2010. [PMID:20506169]
356. Keysor JJ. Jette AM, LaValley MP, Lewis CE, Torner JC, Nevitt MC, Felson DT, and the
Multicenter Osteoarthritis (MOST) Group. Community environmental factors are
associated with disability in older adults with functional limitations: The MOST study. J
Gerontol A Biol Sci Med Sci; 65(4):393-9, 2010 [PMID:19995830].
357. White D, Jette AM, Felson DT, Lavalley MP, Lewis CE, Torner JC, Nevitt MC, Keysor JJ.
Are features of the neighborhood environment associated with disability in older adults?
Disabil Rehabil;32(8):639-45, 2010. [PMID:20205576]
358. Tomasson G, Aspelund T, Jonsson T, Felson DT et al. Effect of rheumatoid factor on
mortality of coronary heart disease. Ann Rheum Dis 69:1649-1654, 2010.
[PMID:19628821]
359. White DK, Zhang Y., Felson DT, Nui J., Keysor JJ, Nevitt MC, Lewis CE, Torner JC, ,
Neogi T, and the Multicenter Osteoarthritis (MOST) Group. The independent effect of pain
in one versus two knees on the presence of low physical function: The MOST Study.
Arthritis Care Res 62:938-943 2010. [PMID:21091572]
27
360. Aletaha D, Neogi T, Silman A, Funovits J, Felson D ....Hawker G. The 2010 ACR/EULAR
classification criteria for rheumatoid arthritis. Arthritis Rheum 62:2569-2581, 2010.
[PMID:20872595]
361. Funovits J, Aletaha D, Bykerk V, Combe B, Dougados M, Emery P, Felson D, et al. The
2010 ACR/EULAR classification criteria for rheumatoid arthritis: methodological report
phase I. Ann Rheum Dis 69: 1589-1596, 2010. [PMID:20699242]
362. Eckstein F, Yang M, Guermazi A....Felson DT. Reference values and Z-scores for
subregional femorotibial cartilage thickness—results from a large population-based sample
(Framingham) and comparison with the non-exposed Osteoarthritis Initiative reference
cohort. OA Cart 18: 1275-1283, 2010. [PMID:20691798]
363. Segal NA, Glass NA, Felson DT, Hurley M, Yang M, Nevitt M, et al. The effect of
quadriceps strength and proprioception on risk for knee osteoarthritis. Med Sci Sports
Exerc 42:2081-2088, 2010. [PMID:20351594]
364. Zhang YQ, Niu J, Felson D, Choi H, Nevitt MC, Neogi T. Methodological challenges in
studying risk factors for progression of knee osteoarthritis. Arthritis Care Res 62:15271532, 2010. [PMID:20617531]
365. Sharma L, Song J, Dunlop D, Felson D, Lewis CE, Segal N, et al. Varus and valgus
alignment and incident and progressive knee osteoarthritis. Ann Rheum Dis 69:1940-1945,
2010. [PMID:20511608]
366. Crema MD, Roemer FW, Zhu Y, Marra MD, Niu J, Zhang Y, Lynch JA, Javaid MK,
Lewis CE, El-Khoury GY, Felson DT, Guermazi A. Subchondral cystlike lesions develop
longitudinally in areas of bone marrow edema-like lesions in patients with or at risk for
knee osteoarthritis: Detection with MR Imaging—The MOST Study. Radiology
256(3):855-62, 2010. [PMID:20530753]
367. Lynch JA, Roemer FW, Nevitt MC, Felson DT, et al. Comparison of BLOKS and
WORMS scoring systems Part I. Cross sectional comparison of methods to assess cartilage
morphology, meniscal damage and bone marrow lesions on knee MRI: Data from the
Osteoarthritis Initiative, Osteoarthritis Cart 18:1393-1401, 2010. [PMID:20816979]
368. Felson DT, Lynch J, Guermazi A et al. Comparison of BLOKS and WORMS scoring
systems Part II. Longitudinal assessment of knee MRI’s for osteoarthritis and suggested
approach based on their performance: data from the Osteoarthritis Initiative. Osteoarthritis
Cart 18:1402-1407, 2010. [PMID:20851202]
369. Neogi T, Nevitt MC, Yang M, Curtis JR, Torner J, Felson DT. Consistency of knee pain:
Correlates and association with function. Osteoarthritis Cart 18:1250-1255, 2010.
[PMID:20708003]
370. Boers M, Felson DT, Wells G, van Tuyl LH, Zhang B, Funovits J, Smolen J. Progress
toward the development of a new definition of remission in rheumatoid arthritis. Bull NYU
Hosp Jt Dis. 68(2):140-2, 2010. [PMID:20632990]
371. Sled EA, Sheehy LM, Felson DT, Costigan PA, Lam M, Cooke TD. Reliability of lower
limb alignment measures using an established landmark-based method with a customized
computer software program. Rheumatol Int. 31:71-77, 2009. [PMID:19882339]
372. Zhang YQ, Nevitt M, Niu J, Lewis CE, Torner J, Guermazi A, Roemer FW, McCullough
C, Felson DT. Fluctuation of knee pain and changes in bone marrow lesions, effusions and
synovitis on MRI: The MOST Study. Arthritis Rheum 63:691-699, 2011
[PMID:21080361].
373. Aletaha D, Neogi T, … Felson DT,…Hawker G: 2010 rheumatoid arthritis classification
28
374.
375.
376.
377.
378.
379.
380.
381.
382.
383.
384.
385.
386.
criteria: an American College of Rheumatology/European League Against Rheumatism
collaborative initiative. Ann Rhem Dis 69:1580-1588. 2010. [PM:20699241]
Crema MD, Roemer FW, Marra MD, Niu J, Lynch JA, Felson DT, Guermazi A: Contrastenhanced MRI of subchondral cysts in patients with or at risk for knee osteoarthritis: the
MOST study. Eur J Radiol 75:e92-e96, 2010. [PM:19767165]
Evangelou E, Valdes AM, … Felson DT … Spector TD: Meta-analysis of genome-wide
association studies confirms a susceptibility locus for knee osteoarthritis on chromosome
7q22. Ann Rheum Dis 70:349-355, 2011. [PM:21068099]
Guermazi A, Hayashi D, Roemer FW, Niu J, Yang M, Lynch JA, Torner JC, Lewis CE,
Sack B, Felson DT, Nevitt MC: Cyst-like lesions of the knee joint and their relation to
incident knee pain and development of radiographic osteoarthritis: the MOST study.
Osteoarthritis Cart 18:1386-1392. 2010. [PM:20816978]
Kerkhof HJ, Meulenbelt I, Akune T, … Felson DT … van Meurs JB: Recommendations
for standardization and phenotype definitions in genetic studies of osteoarthritis: the
TREAT-OA consortium. Osteoarthritis Cart 1-11, 2010. [PM:21059398]
Neogi T, Aletaha D, Silman AJ, Felson DT, Hawker G: The 2010 American College of
Rheumatology/European League Against Rheumatism classification criteria for rheumatoid
arthritis: Phase 2 methodological report. Arthritis Rheum 62:2582-2591, 2010.
[PM:20872596]
Panoutsopoulou K, Southam L, Elliott KS, Felson DT, Loughlin J: Insights into the genetic
architecture of osteoarthritis from stage 1 of the arcOGEN study. Ann Rheum Dis, 70:864867, 2010. [PM:21177295]
Roemer FW, Lynch JA, Niu J, Zhang Y, Crema MD, Tolstykh I, El-Khoury GY, Felson
DT, Lewis CE, Nevitt MC, Guermazi A: A comparison of dedicated 1.0 T extremity MRI
vs large-bore 1.5 T MRI for semiquantitative whole organ assessment of osteoarthritis: the
MOST study. Osteoarthritis Cart 18:168-174, 2010. [PM:19766580]
Guermazi A, Roemer FW, Hayashi D,....Felson DT. Assessment of synovitis with contrastenhanced MRI using a whole joint semiquantitative scoring system in persons with or at
high risk of knee osteoarthritis - The MOST Study. Ann Rheum Dis, 70:805-811, 2011
[PMID:21187293]
Sheehy L, Felson D, Zhang Y, et al. Does measurement of the anatomic axis consistently
predict hip-knee-ankle (HKA) for knee alignment studies in osteoarthritis? Analysis of
long limb radiographs from the MOST Study. Osteoarthritis Cart 19:58-64, 2011.
[PMID:20950695]
Gross KD, Felson DT, Niu J, et al. Flat feet are associated with knee pain and cartilage
damage in older adults. Arthritis Care Res, 63(4): 937-944, 2011. [PMID:21717597]
van Vollenhoven RF, Felson D, Strand V, et al. American College of Rheumatology hybrid
analysis of certolizumab pegol plus methotrexate in patients with active rheumatoid
arthritis: data from a 52-week phase III trial. Arthritis Care Res. 63:128-134, 2011.
[PM:20799264]
Felson DT, Smolen JS, Wells G, Zhang B, et al. American College of Rheumatology/
European League Against Rheumatism provisional definition of remission in rheumatoid
arthritis for clinical trials. Arthritis Rheum. 63:573-586, 2011. [PM:21294106]
Felson DT, Smolen JS, Wells G, et al. American College of Rheumatology/ European
League Against Rheumatism provisional definition of remission in rheumatoid arthritis for
clinical trials. Ann Rheum Dis 70:404-413. 2011. [PM:21292833]
29
387. Hunter DJ, Harvey W, Gross KD, Felson D, et al. A randomized trial of patellofemoral
bracing for treatment of patellofemoral osteoarthritis. Osteoarthritis Cart 19:792-800, 2011.
[PM:21232620].
388. Hayashi D, Roemer FW…Felson DT et al. Imaging of synovitis in osteoarthritis: Current
status and outlook. Semin Arthritis Rheum (in press) , 2011 [PM:21295331].
389. Vlad S, Neogi T, Aliabadi P, Fontes JDT, Felson DT. No association between markers of
inflammation and osteoarthritis of the hands and knee. J Rheumatol 38:1665-1670, 2011
[PM:21572158].
390. Haugen IK, Niu J, Aliabadi P, Felson DT, Englund M. The association between finger
length pattern and osteoarthritis, knee injury and meniscal lesions: the Framingham
Community Cohort. Arthritis Rheum 63:2284-2288, 2011 [PM:21506096].
391. Haugen IK, Englund M, Aliabadi P…Felson DT. Prevalence, incidence and progression of
hand osteoarthritis in the general population: the Framingham Osteoarthritis Study. Ann
Rheum Dis 70:1581-1586, 2011 [PM:21622766].
392. Dudda M, Kim Y-J, Zhang Y…Felson DT. Morphological differences between Chinese
and Caucasian female hips: could they account for the ethnic difference in hip
osteoarthritis? Arthritis Rheum (in press), 2011 [PM:21647861].
393. Englund M, Felson DT, Guermazi A…Nevitt MC. Risk factors for medial meniscal
pathology on MRI in middle aged and elderly persons: a multicenter prospective cohort
study in the U.S. Ann Rheum Dis 70: 1733-1739, 2011 [PM:21646417].
394. Roemer FW, Guermazi A, Felson DT….Zhang Y. Presence of MRI detected joint effusion
and synovitis increases the risk of cartilage loss in knees without osteoarthritis at 30 month
follow-up: the MOST Study. Ann Rheum Dis 18:168-174, 2011 [PM:21791448]
395. Stefanik JJ, Roemer FW, Zumwalt AC…Felson DT. Association between measures of
trochlear morphology and structural features of patellofemoral joint osteoarthritis on MRI:
the MOST Study. J Orthop Res (in press), 2011 [PMID:21710542].
396. Collins NJ, Misra D, Felson DT…Roos EM. Patient reported outcomes of knee function.
Arthritis Care Res (in press), 2011.
397. Felson DT, Niu JB, Guermazi A, Sack B, Aliabadi P. Defining radiographic incidence and
progression of knee osteoarthritis: suggested modifications of the Kellgren and Lawrence
scale. Ann Rheum Dis (in press), 2011.
398. Gibson N, Guermazi A, Clancy M,…Felson DT. Relation of hand enthesophytes with knee
enthesopathy: is osteoarthritis related to a systemic enthesopathy? J Rheumatol (in press),
2011.
399. Wise BL, Felson DT, Clancy M et al. Consistency of knee pain and risk of knee
replacement: the multicenter osteoarthritis study. J Rheumatol 38:1390-1395, 2011 [PMID:
21498481]
400. Misra D, Booth SL, Crosier MD, Ordovas JM, Felson DT, Neogi T. Matrix Gla Protein
polymorphism, but not concentration, is associated with radiographic hand osteoarthritis. J
Rheumatol 38:1960-1965, 2011 [PMID: 21724703]
401. Van Tuyl LHD, Britsemmer K, Wells G….Felson DT, Boers M. Remission in early
rheumatoid arthritis defined by 28 joint counts: limited consequences of residual disease
activity in the forefeet on outcome. Ann Rheum Dis (in press) 2011.
402. McWalter EJ, Hunter DJ, Harvey WF, McCree P, Hirko KA, Felson DT, Wilson DR. The
effect of a patellar brace on three-dimensional patellar kinematics in patients with lateral
patellofemoral osteoarthritis. OA Cart 19:801-808, 2011. [PM:21397707]
30
403. Nguyen UDT, Zhang Y, Zhu Y, Niu J, Zhang B, Aliabadi P, Felson DT. Increasing
prevalence of knee pain and symptomatic knee osteoarthritis. Ann Intern Med, in press.
404. Dixon WG, Felson DT. Is antiTNF therapy safer than previously thought? JAMA, in press.
405. White DK, Felson DT, Niu J et al. Reasons for functional decline despite reductions in
knee pain: the Multicenter Osteoarthritis Study. Phys Ther, 2011, in press.
406. Roemer FW, Guermazi A, Niu J, Zhang Y, Mohr A, Felson DT. Prevalence of MRIdefined atrophic and hypertrophic phenotypes of knee osteoarthritis in a population-based
cohort. Arthritis Rheum 2012.
407. Baker KR, Matthan NR, Lichtenstein A…Felson DT. Association of Plasma n-6 and n-3
polyunsaturated fatty acids with synovitis in the knee: the MOST Study. Osteoarthritis
Cart 2012, in press.
408. Gross KD, Niu J, Stefanik JJ…Felson DT. Breaking the Law of Valgus: the surprising and
unexplained prevalence of medial patellofemoral cartilage damage. Ann Rheum Dis, 2012, in
press.
409. Xu L, Hayashi D, Roemer FW, Felson DT, Guermazi A. Magnetic resonance imaging of
subchondral bone 1 marrow lesions in association with osteoarthritis. Seminars Arthritis Rheum,
in press.
Book Chapters and Invited Non-peer reviewed Review Articles
1.
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12.
Read M, Felson D: Malnutrition, Learning, and Behavior. Washington, DC: DHEW Pub No
(NIH), 76-1036, 1976.
Felson D: Soft Tissue Rheumatism. In: Heffernan JJ, Witzburg RA, Cohen AS, eds. Clinical
Problems in Acute Care Medicine, 1st ed. Philadelphia: W.B. Saunders, 590-595, 1989.
Felson D: Acute Low Back Pain. In: Heffernan JJ, Witzburg RA, Cohen AS, eds. Clinical
Problems in Acute Care Medicine, 1st ed. Philadelphia: W.B. Saunders, 596-600, 1989.
Felson D: Crystal-Induced Arthritis. In: Heffernan JJ, Witzburg RA, Cohen AS, eds. Clinical
Problems in Acute Care Medicine, 1st ed. Philadelphia: W.B. Saunders, 614-618, 1989.
Felson D: Approach to patient with Acute Rheumatic Disease. In: Heffernan JJ, Witzburg
RA, Cohen AS, eds. Clinical Problems in Acute Care Medicine, 1st ed. Philadelphia: W.B.
Saunders, 585-589, 1989.
Felson DT: The epidemiology of osteoarthritis. Rheum Dis Clin N Am 16:499-512, 1990.
Felson DT: Obesity and osteoarthritis of the knee. Bull Rheum Dis 41:6-7, 1992.
Felson DT: The course of osteoarthritis and factors that affect it. Rheum Dis Clin N Am
19:607-615, 1993.
Felson D: Epidemiology of the Rheumatic Diseases. In: McCarty D & Koopman W, eds.
Arthritis and Allied Conditions - A Textbook of Rheumatology, 12th ed., Malvern, PA: Lea
& Febiger, 1993, 17-48.
Felson DT: Epidemiology of rheumatic diseases. Curr Opin Rheum 2:301-308, 1990.
Felson DT: Invited commentary: outcome measures in rheumatoid arthritis. In: Biologic
Agents in Autoimmune Diseases, Proceedings: Early Decisions in DMARD Development III,
Arthritis Foundation, 1994, 129-132.
Felson DT: Do occupation-related physical factors contribute to arthritis? Bailliere's Clin
Rheumatol 8:63-77, 1994.
31
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15.
16.
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18.
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23.
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29.
30.
31.
32.
33.
34.
Felson D: Second Line Anti-Rheumatic Therapies. In: Wolfe F & Pincus T, eds. Rheumatoid
Arthritis: Critical Issues in Etiology, Assessment, Prognosis and Therapy, New York: Marcel
Dekker, Inc., 1994, pp 341-356
Felson D: The epidemiology of osteoarthritis: prevalence and risk factors. In: Osteoarthritic
Disorders. American Academy of Orthopaedic Surgeons, pp. 13-24, 1994.
Dieppe P, Altman RD, Buckwalter JA, Felson DT, Hascall V, Lohmander LS, Peterfy CG,
Roos H, Kuettner KE: Standandization of methods used to assess the progression of
osteoarthritis of the hip or knee joints. In: Osteoarthritic Disorders. American Academy of
Orthopaedic Surgeons, pp. 481-496, 1994.
Felson DT, Anderson JJ: Methodologic and statistical approaches to criteria development in
rheumatic diseases. Bailliere's Clin Rheumatol 9:253-266, 1995.
Boers M, van Riel P, Felson DT, Tugwell P: Assessing the activity of rheumatoid arthritis.
Bailliere's Clin Rheumatol 9:305-318, 1995.
Felson DT, Chaisson CE: Understanding the relationship between body weight and
osteoarthritis. Bailliere’s Clin Rheumatol 11:671-682, 1997.
Felson D: Osteoarthritis. In: Conn RB, Borer WZ, Snyder JW, eds., Current Diagnosis 9,
986-988, 1997.
Felson D: Epidemiology of the rheumatic diseases. In: Koopman W, ed., Arthritis and Allied
Conditions, 13th edition, 1997, pp 3-34.
Felson DT: Non-medicinal therapies for osteoarthritis. Bull Rheum Dis 47:5-8, 1998.
[PMID:9557365]
Felson D: Epidemiology of osteoarthritis. In: Brandt K, Lohmander S and Doherty M, eds.,
Osteoarthritis, 1998, pp 13-22.
Lohmander LS, Felson DT: Defining and validating the clinical role of molecular markers in
osteoarthritis. In: Brandt K, Lohmander S, and Doherty M eds., Osteoarthritis, 1998, pp. 519530.
Felson DT, Nevitt M: The effects of estrogen on osteoarthritis. Curr Opin Rheumatol 10:269272, 1998. [PMID:9608332]
Felson DT: Occupation-related physical factors and osteoarthritis. In: Kaufman LD, Varga J,
eds., Rheumatic Diseases and the Environment, 1999, pp. 189-196
Meenan RF, Felson DT: Clinical Epidemiology. In: Armitage P and Colton T, eds.
Encyclopedia of Biostatistics.
Felson DT: Epidemiology of the rheumatic diseases. In: Koopman W., ed., Arthritis and
Allied Conditions, 14th Edition, 2001, pp. 3-38.
Amin S, Felson DT: Osteoporosis in men. Rheum Dis Clin N Am, 17:19-48, 2001.
[PMID:11285995]
Felson DT, Edmond SL: Obesity: Musculoskeletal Complications. In: Eckel RH ed., Obesity:
Mechanisms and Clinical Management, 2003, pp. 399-414.
Felson DT: Musculoskeletal Disorders. In: Encyclopaedia of Public Health (in press).
Felson DT: Epidemiology of Osteoarthritis. In: Brandt K, Lohmander S, Doherty M, eds.
Osteoarthritis, 2nd edition, 2003, pp 9-16.
Fraenkel L, Felson DT: Osteoarthritis. In: Hazzard WR, Blass JP, Halter JB, Ouslander JG,
Tinetti ME, Principles of Geriatric Medicine and Gerontology 5th edition, 2003, pp 961-972.
Felson DT: An update on the pathogenesis and epidemiology of osteoarthritis. In Weissman
B editor, Arthritis Imaging. Radiol Clin N Am 42: 1-9, 2004. [PMID:15049520]
Felson DT, Nevitt MC: Epidemiologic studies for osteoarthritis: new versus conventional
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study design approaches. Rheum Dis Clin N Am 30: 783-798, 2004. [PMID:15488693]
Felson DT: The sources of pain in knee osteoarthritis. Curr Opin Rheumatol 17: 624-628,
2005. [PMID:16093843]
Felson DT. Glucosamine and chondroitin sulfate in knee osteoarthritis: where now? Nature
Clinical Practice Rheumatology. 2(7):356-7, 2006. [PMID:16932718]
Felson DT: Osteoarthritis. In Current Diagnosis & Treatment in Rheumatology, 2nd Edition,
339-344, 2007.
Felson DT: Osteoarthritis. In Harrison’s Principles of Internal Medicine, eds Fauci,
Braunwald, Kasper, Hauser, Longo, Jameson, Loscalzo. 17th Edition, 2158-2165, 2008.
Felson DT: New evidence on Glucosamine Efficacy. Nature Clin Practice Rheumatol, in
press
Oldfield V, Felson DT: Exercise therapy and orthotic devices in rheumatoid arthritis:
evidence based review. Curr Opin Rheumatol 20: 353-359, 2008. [PMID:18388530]
Felson DT. Toward optimal health: managing arthritis in women. An interview with David
T. Felson by Jodi R. Godfrey. J Womens Health (Larchmt). 2008 Jun; 17(5): 729-34.
[PMID:18481922]
Felson DT: Developments in the clinical understanding of osteoarthritis. In: The Scientific
Basis of Rheumatology: A Decade of Progress. Eds Lipsky, Maini, in press.
Felson DT: Clinical Trials in Rheumatology. In: 75th Anniversary of the American College
of Rheumatology. Ed by Pisetsky, in press.
Felson DT: Osteoarthritis. In Harrison’s Principles of Internal Medicine, eds. Fauci,
Kasper, Hauser, Longo, Jameson, Loscalzo, 18th Edition, 2011.
Felson DT: Osteoarthritis. In Current Diagnosis & Treatment in Rheumatology, 3rd Edition,
in press.
Felson, DT. Arthroscopy as a treatment for knee osteoarthritis. Best Pract Res Clin
Rheumatol; 24(1):47-50, 2010. [PMID:20129199]
Felson DT, Zhang YQ: Local and systemic risk factors for incidence and progression of
osteoarthritis. In Rheumatology, 5th Edition. Eds. Hochberg, Silman, Smolen, Weinblatt,
and Weisman; 1717-1723, 2010.
Felson DT: Imaging abnormalities that correlate with joint pain. Br J Sports Med 2011, in
press.
Felson DT. Osteoarthritis in 2010: New takes on treatment and prevention. Nat. Rev.
Rheumatol. 7:75-76, 2011. [PM:21289610]
Felson DT. Virtual joint replacement as an outcome measure in OA. Nat Rev Rheumatol,
in press, 2012
Books
1.
Felson DT, Schaible HG, eds, Pain in Osteoarthritis, Wiley Blackwell, 2009
33
SCIENTISTS WHO TRAINED PRIMARILY WITH DR. FELSON
AND THEIR CURRENT POSITIONS
 Douglas Kiel, MD, MPH; Professor of Medicine, Harvard Medical School, Director,
Framingham Osteoporosis Study
 Janet E. Pope, MD, MPH; Professor of Medicine, University of Western Ontario
 Liana Fraenkel, MD, MPH; Associate Professor of Medicine, Yale University School of
Medicine
 Timothy McAlindon, MD, MPH, Professor of Medicine and Director of the Division of
Rheumatology, Tufts-New England Medical Center
 Marian T. Hannan, DSc, Associate Professor of Medicine, Harvard Medical School, Director,
Framingham Foot Study
 Shreyasee Amin, MD, MPH, Associate Professor of Medicine, Mayo Clinic School of Medicine
 Elizabeth Samelson, Ph.D., Assistant Professor of Medicine, Harvard Medical School
 Ram R. Miller, MD, MSc., Assistant Professor of Medicine, U. of Maryland
 Grace H. Lo, MD, MSc., Assistant Professor of Medicine, Tufts University
 Tuhina Neogi, MD, DSc, Associate Professor of Medicine, Boston University
 Catherine L. Hill, MBBS, MSc, MD Senior Lecturer in Medicine, University of Adelaide
 Kristin Baker, Ph.D., Assistant Professor of Medicine, Boston University
 Steven Vlad, MD, MSc, Assistant Professor of Medicine, Boston University
 K. Douglas Gross, DPT, Assistant Professor of Physical Therapy, MGH Institute of Health
Professions
 Barton Wise, MD, MSc, Assistant Professor of Medicine, U. California, Davis
 Martin England, MD, MSc, Associate Professor of Orthopedics, Lund University
 Julie Keysor, PT, PhD, Associate Professor, Sargent College, Boston University
 Dan K. White, PT, PhD, Research Assistant Professor, Sargent College, Boston University
34
GRANTS AND FELLOWSHIPS
N.I.H. AND FOUNDATION GRANTS
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
Medical Foundation Fellowship, 1984, for study of osteoarthritis of the knee.
Arthritis Foundation Arthritis Investigator Award 1984-87 for study of osteoarthritis of the
knee.
Co-Principal Investigator of Framingham Heart Study Knee Osteoarthritis Study. Funded by
N.I.H. through Multipurpose Arthritis Center Grant, 1984-1987.
Principal Investigator of Framingham Heart Study evaluation of the risk factors for Hip
Fracture. Funded by R.W. Johnson Foundation, 1986-89.
Principal Investigator of Framingham Osteoporosis Study, funded by N.I.H. through
Multipurpose Arthritis Center Grant, 1987-1992.
Principal Investigator of Meta-analysis in Rheumatology grant funded by N.I.H. through
Multipurpose Arthritis Center Grant, 1987-1992.
Principal Investigator of Study of Osteoarthritis and Physical Disability in the Elderly. RO1
funded by N.I.H., 1988-1992.
Principal Investigator of Study of Habitual Physical Activity as a Cause of Knee
Osteoarthritis, Arthritis Foundation Clinical Project Grant, 1989-1992.
Principal Investigator of Study of Rheumatoid Arthritis Drug Therapy in the Elderly. RO1
funded by N.I.A.M.S./N.I.H., 1991-1994.
Principal Investigator of Longitudinal Study of Osteoarthritis in an Elderly Cohort. RO1
funded by N.I.A./N.I.H., 1991-1996.
Co-Principal Investigator of Study on Risk Factors for Vertebral Fracture and Bone Loss.
RO1 funded by N.I.A.M.S./N.I.H. 1991-1996
Principal Investigator of Study on the Heritability of Osteoarthritis, funded through
Multipurpose Arthritis and Musculoskeletal Diseases Center Grant 1992-1997.
Principal Investigator of Multipurpose Arthritis and Musculoskeletal Disease Center Grant
funded by N.I.A.M.S., 1993-2001 (two funding cycles).
Co-Principal Investigator of Study on Whether Rheumatologists affect patient
outcomes, funded by American College of Rheumatology, 1994-1995.
Principal Investigator of Study of the effect of alcohol consumption on change in bone
density, funded by Alcohol Beverage Medical Research Foundation, 1996.
Principal Investigator of Study of Knee MRI in subjects with and without osteoarthritis.
Arthritis Foundation Clinical Sciences Grant, 1996-1999.
Principal Investigator of Study of Osteoarthritis in Chinese vs. Caucasian populations. RO-1
funded by N.I.A.M.S. 1996-2001.
Principal Investigator of Boston University Clinical Research Training Program NIH-K30
funded 1999-2009.
Principal Investigator of Framingham Osteoarthritis Study, RO-1 funded by N.I.A., 20012006.
Principal Investigator of Multidisciplinary Clinical Research Center Grant. P60 funded by
N.I.A.M.S. 2001-2006.
Principal Investigator of Grant on Correlates of Articular Cartilage Volume and Thickness
in Framingham Subjects. Arthritis Foundation Clinical Sciences Grant, 2001-2006.
35
22.
23.
24.
25.
26.
27.
28.
29.
30.
30.
31.
32.
Principal Investigator of Multicenter Osteoarthritis Study (MOST). U-01 funded by N.I.A.,
2001-2008.
Principal Investigator of OA Biomarkers Grant. U-01 funded by NIAMS, 2003-2007.
Principal Investigator of Clinical Research Training Program (K30). Funded by NCRR/NIH
2005-2008.
Principal Investigator, Multidisciplinary Clinical Research Center Grant (P60). Funded by
NIAMS/NIH 2006-2011.
Principal Investigator of Grant on Structural Correlates of Knee Pain. R01 funded by
NIAMS/NIH 2006-2010.
Principal Investigator of Grant to examine Relation of Mechanical Alignment to other risk
factors in knee osteoarthritis. R01 funded by NIAMS/NIH 2006-2012.
Principal Investigator, Multicenter Osteoarthritis Study (MOST) renewal U01. NIA/NIH
2008-2014.
CoDirector of Trainin, Boston University CTSA grant, 2008-2011
Director of Training, Boston University CTSA grant, 2011-2013
Co-investigator on 2 NIH funded grants as of 2008
Principal Investigator of Osteoarthritis Programme Grant from Arthritis Research UK
through the University of Manchester (2009-2013).
CoInvestigator/CoLead, Biomedical Research Unit in Musculoskeletal Disease, University
of Manchester, UK
INDUSTRY GRANTS
1.
2.
3.
4.
5.
6.
7.
Principal Investigator of Study on Estrogen and Osteoarthritis at Fallon Clinic. Funded by
Wyeth Ayerst, 1992-1994.
Principal Investigator of Study of Estrogen and Osteoarthritis in Framingham Study, funded
by Wyeth Ayerst, 1995.
Principal Investigator of Study of MRI Use in Detecting Progression of Knee Osteoarthritis.
Funded by Bayer, 1995-1999.
Principal Investigator of Analytic Center for Multicenter Trial of Prosorba treatment
of
rheumatoid arthritis, funded by Cypress Biosciences, 1996-1998.
Principal Investigator, Factors affecting response to treatment in rheumatoid arthritis,
funded by Cypress Biosciences, 1998.
Co-Principal Investigator of HERS WALK, Clinical trial of the effect of estrogen on knee
symptoms in postmenopausal women, funded by Wyeth Ayerst, 1998-1999.
Principal Investigator, Osteophytes and Alendronate Treatment, funded by Merck, 20042005.
36