BIOGRAPHICAL SKETCH Provide the following information for the key personnel in the order listed for Form Page 2. Follow the sample format for each person. DO NOT EXCEED FOUR PAGES. NAME POSITION TITLE Meyer, Clifford Alexander Research Fellow EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) INSTITUTION AND LOCATION DEGREE (if applicable) University of Cape Town, Cape Town, South Africa University of Cape Town, Cape Town, South Africa B.Sc. Princeton University, Princeton, NJ Ph.D. Harvard School of Public Health, Dana-Farber Cancer Institute, Boston, MA Post-doctoral M.Sc. YEAR(s) FIELD OF STUDY 1990-1993 Chemical Engineering 1994-1996 Chemical Engineering 1997-2003 Chemical Engineering 2003-2005 Biostatistics Positions and Experiences 1994-1996 M.Sc. research on algorithm development for the solution of phase and chemical equilibrium problems 1997-2003 Ph.D. research on the design and implementation of algorithms for global optimization 2003-2005 Research fellow, Department of Biostatistics, Harvard School of Public Health, Dept. of Biostatistical Science, Dana-Farber Cancer Institute, Boston Honors and Awards 1994-1996 MINTEK fellowship for M.Sc. research 1996 S2A3 Gencor Bronze Medal award by the South African Institute for the Advancement of Science for the best masters dissertation in the Science, Engineering and Health Science Faculties 1999 Ticona Award for assistance in instruction 2005-present Roadmap Fellow: Interdisciplinary Training Program in Genetics and Complex Diseases Publications Meyer, C.A., C.L.E. Swartz A regional convexity test for global optimization: Application to the phase equilibrium problem, Computers and Chemical Engineering (1998). Floudas, C.A., P.M. Pardalos, C.S. Adjiman, W.R. Esposito, Z. Gumus, S.T. Harding, J.L. Klepeis, C.A. Meyer, and C.A. Schweiger, Handbook of Test Problems for Local and Global Optimization, Kluwer Academic Publishers, (1999). Meyer, C.A., A. Neumaier, C.A. Floudas, Global Optimization with Non-Factorable Constraints, Industrial and Engineering Chemistry Research (2002) Meyer C.A., C.A. Floudas, Trilinear Monomials with Mixed Sign Domains: Facets of the Convex and Concave Envelopes, Journal of Global Optimization, accepted for publication (2003). Meyer, C.A., C.A. Floudas, Trilinear Monomials with Positive or Negative Domains: Facets of the Convex and Concave Envelopes'', Frontiers in Global Optimization, (Eds. P.M. Pardalos and C.A. Floudas), (2003). Meyer, C.A. and C.A. Floudas, Convex Underestimation of Twice Continuously Differentiable Functions via Piecewise Quadratic Perturbation, Foundations of Computer Aided Process Design Proceedings, Princeton (2004). Akrotirianakis, I.G., C.A. Meyer and C.A. Floudas, The Role of the Off-Diagonal Elements of the Hessian Matrix in the Construction of Tight Convex Underestimators of Nonconvex Functions, Foundations of Computer Aided Process Design Proceedings, Princeton (2004). Li W, C.A. Meyer, X.S. Liu, A hidden Markov model for analyzing ChIP-chip experiments on genome tiling arrays and its application to p53 binding sequences. ISMB2005. Bioinformatics. (2005). Carroll, J.S., X.S. Liu, A.S. Brodsky, W. Li, A.J. Szary, C.A. Meyer, W. Shao, E.V. Hestermann, T.R. Geistlinger, E.A. Fox, P.A. Silver, M. Brown, Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell. (2005). Brodsky AS, Meyer CA, Hall G, Swinburne IA, Keenan BJ, Liu XS, Fox EA, Silver PA. Genomic mapping of RNA polymerase II reveals sites of co-transcriptional regulation in human cells. Genome Biology. (2005) Research Support: PHS 398/2590 (Rev. 05/01) Page _______ Biographical Sketch Format Page Meyer, Clifford ONGOING/COMPLETED N/A PHS 398/2590 (Rev. 05/01) Page _______ Biographical Sketch Format Page