Deniz Ağırbaşlı M.D. PhD.
Birth place:
İstanbul
E-mail: deniz.agirbasli@acibadem.edu.tr
detanyildiz@yahoo.com
Education:

Marmara University,Faculty of Medicine, Department of Molecular Biology and GeneticsIstanbul,Turkey........................................................................................................(2009)

Karadeniz Technical University, Faculty of Medicine-Trabzon,Turkey……….....(1999)
Academical Titles:

PhD Molecular Biology and Genetics

Doctor of Medicine
Responsibilities:
1.
Staff phycician in E.R ,V.K.V American Hospital, Istanbul,Turkey…………….(1999-2001)
2.
Visiting Phisician and researcher: ‘MDR analysis of gene-gene interactions among PAI-1,
MTHFR, NOS polimorphisms’ J. Phillips Lab Vanderbilt University Medical CenterNashville, TN USA. Program director: John A Phillips III M.D. (The study is published in
Coronary Artery Disease Journal)……… ………………………………...…(2002-2003)
3.
PhD Thesis: The Effect of Lecithin Cholesterol Acyltransferase Genotypes, Enzyme Levels
and Activity on low levels of High Density Lipoprotein In Turkish Population. Mentor:
Beyazıt Çırakoğlu, Professor of Molecular Biology and Genetics, Marmara University,
School of Medicine, Istanbul, Turkey....................................................................(2003-2009)
4.
Co-investigator in post graduate thesis of Hasan Saim Özturhan M.D. Marmara University
Division of Cardiology. ‘The interaction between premature coronary atherosclerosis and
ACE I/D and MTHFR C677T gene polymorphisms in Turkish population’..................(2008)
5.
Co investigator in post graduate thesis of Mutlu Çağan Sümerkan. Marmara University
Division of Cardiology. ‘The interaction between Lipoprotein Lipase S447X gene
polymorphism and premature coronary atherosclerosis in Turkish
population’………………………...................................................................................(2009)
Membered Societies:
1. Turkish Medical Association
2. American Heart Association
3. Turkish Proteomics Society
Honored Prizes:
1.
2.
6-9. 5. 2006
‘Congress Fellowship Award’ with the poster ‘Interaction among
MTHFR, PAI-I and eNOS gene polymorphisms predict the severity of coronary artery
disease in Turkish patients.’ presented in European Society of Human Genetics (ESHG)
Conference, Amsterdam, 2006.
31.5-3.6.2008
‘Congress Fellowship Award’ with the poster ‘Effects of LCAT
polymorphisms on HDL-C levels in Turkish population.’ presented in European Society of
Human Genetics (ESHG) Conference, Barcelona, 2008.
Publications
Articles:
1.
White MJ, Eren F, Ağırbaşlı D, Chen J, Hu T, Moore JH, Williams SM, Ağırbaşlı M. A
Systems Genetics Approach to Dyslipidemia in Children and Adolescents. OMICS. 2015
Apr;19(4):248-59.
2.
White MJ, Eren F, Agirbasli D, Williams SM, Agirbasli M. SHBG Gene Polymorphism
(rs1799941) Associates with Metabolic Syndrome in Children and Adolescents.
PLoS One. 2015 Feb 3;10(2):e0116915.
3.
Agirbasli M, Eren F, Agirbasli D, White MJ, Williams SM. Multi-locus candidate gene
analyses of lipid levels in a pediatric Turkish cohort: lessons learned on LPL, CETP, LIPC,
ABCA1, and SHBG. OMICS. 2013 Dec;17(12):636-45.
4.
Agirbasli D, Ulman YI. Coronary artery disease from a perspective of genomic risk score,
ethical approaches and suggestions. Anadolu Kardiyol Derg 2012 Mar;12(2):171-7.
5.
Agirbasli D, Cirakoglu B, Eren F, Sumerkan M, Aksoy S, Aral C, Agirbasli M. Effects of
lecithin: Cholesterol acyltransferase genotypes, enzyme levels, and activity on high-density
lipoprotein levels. J Clin Lipidol. 2011 May-Jun;5(3):152-8.
6.
Agirbasli M, Guney A, Ozturhan H, Agirbasli D, Ulucan K, Sevinc D, Kirac D, Ryckman K,
Williams SM. Multifactor dimensionality reduction analysis of MTHFR, PAI-1, ACE,
PON1, and eNOS gene polymorphisms in patients with early onset coronary artery disease.
Eur J Cardiovasc Prev Rehabil. 2011 Dec;18(6):803-9.
7.
Agirbasli M, Sumerkan MC, Eren F, Agirbasli D. The S447X variant of lipoprotein lipase
gene is inversely associated with severity of coronary artery disease. Heart Vessels 2011
Jul;26(4):457-63.
8.
Agirbasli D, Agirbasli M, Williams SM, Phillips JA 3rd.Interaction among 5,10
methylenetetrahydrofolate reductase, plasminogen activator inhibitor and endothelial nitric
oxide synthase gene polymorphisms predicts the severity of coronary artery disease in
Turkish patients. Coron Artery Dis. 2006 Aug;17(5):413-7.
Proceedings:
1.
Agirbasli M, Ozturhan HS, Ulucan K, Agirbasli D, Sevinc D, Ryckman K, Williams SM,
Guney AI. INTERACTION AMONG MTHFR, PAI-1, ACE, PON AND E-NOS GENE
POLYMORPHISMS CAN PREDICT THE PRESENCE AND SEVERITY OF EARLY
ONSET CORONARY ARTERY DISEASE. J Am Coll Cardiol 2009;53(10):A444
2.
Ozturhan HS, Guney I, Sevinc D, Agirbasli D, Baykan O, Agirbasli M.
FREQUENCY, SIGNIFICANCE AND ASSOCIATION OF ACE AND MTHFR GENE
POLYMORPHISMS IN TURKISH PATIENTS WITH EARLY ONSET CORONARY
ARTERY DISEASE. Atherosclerosis suppl. 2008; 9(1):108
3.
Schwandt P, Haas G, Baykan A, Agirbasli D, Liepold E, Agirbasli M
COMPARISON OF ANTROPOMETRIC MEASUREMENTS IN TURKISH
CHILDREN FROM ISTANBUL, TURKEY VERSUS NURNBERG, GERMANY.
Atherosclerosis Suppl. 2008;9(1):265
Presentations:
1. Agirbasli D, Cirakoglu B , Eren F, Sumerkan M, Aksoy S, Aral C, Agirbasli M. THE
EFFECT OF LECITHIN: CHOLESTEROL ACYLTRANSFERASE GENOTYPES,
ENZYME LEVELS AND ACTIVITY ON HIGH DENSITY LIPOPROTEIN LEVELS IN
TURKISH POPULATION. Circulation. 2010;122(21):A21482.
2. Agirbasli D, Williams SM, Agirbasli M. MULTIFACTOR DIMENSIONALITY
REDUCTION (MDR) ANALYSIS FOR GENETIC MODELING OF COMPLEX
DISEASES. Clin Genet 2010;78(1):42.
3. Agirbasli D, Akyerli CB, Acun T, Keller A, Yakicier MC. LincRNA EXPRESSION IN
HEPATOCELLULAR CARCINOMA. Clin Genet. 2010;78(1):74.
4. Akyerli CB, Agirbasli D, Acun T, Sahin O, Yakicier MC. ANALYSIS OF GENETIC
VARIATIONS CAUSED BY ENVIRONMENTAL FACTOR AFLATOXIN IN
HEPATOCELLULAR CARCINOMA. Clin Genet. 2010;78(1):74.
5. Agirbasli D, Agirbasli M., Sumerkan M, Aral C, Aksoy S, Karabulut S, Cirakoglu B.
EFFECTS OF LCAT POLYMORPHISMS ON HDL-C LEVELS IN TURKISH
POPULATION. Eur J Hum Genet 2008;16(2):322
6. Agirbasli D, Agirbasli M, Williams SM, Phillips JA. INTERACTION AMONG 5,10
METHYLENETETRAHYDROFOLATE REDUCTASE, PLASMINOGEN ACTIVATOR
INHIBITOR AND ENDOTHELIAL NITRIC OXIDE SYNTHASE GENE
POLYMORPHISMS PREDICTS THE SEVERITY OF CORONARY ARTERY DISEASE
IN TURKISH PATIENTS.Eur J Hum Genet 2006;14(1):117-118.
7. Ağırbaşlı D, Ağırbaşlı M, Erarslan S, Alkan T, Kırdar B, Byrne DW, Phillips JA. PAI-1
HIND III RESTRICTION FRAGMENT LENGTH POLYMORPHISM AS A RISK
FACTOR FOR EARLY ONSET CORONARY ARTERY DISEASE. Thrombosis,
Hemostasis and Angiology Congress 2003
8. Tanyıldız D, Aydın K, Köksal İ, Volkan S, Öksüz R, Çaylan R ‘HIV AND AIDS
AWARENESS AMONG PUBLIC AND STUDENTS IN TRABZON- TURKEY’
International Medical Students’ Congress in Belgrade-Yugososlavia 1997
Presentations in Turkish:
1.
Ağırbaşlı D, Ülman YI .VI. Medical Ethics Congress,"New Horizon in Bioethics”
November, 25-26, 2010, "Kompleks hastalıklarda genomik risk skorlamasının geleceği
ve etik sorular"