4 BBBB - Bled International
Conference on Pharmaceutical
Sciences
th
Slovenian Pharmaceutical Society and
University of Ljubljana, Faculty of Pharmacy
are organizing the
New Trends in Drug Discovery,
Delivery Systems and Laboratory Diagnostics
Bled, Slovenia, 29 September th – 1 October 2011 st
Second Announcement
www.bbbb-eufeps.org
Dear colleagues,
As local hosts and Chairpersons of 4th BBBB Conference,
it is our great pleasure, to invite you to participate in 4th BBBB Conference entitled:
NEW TRENDS IN DRUG DISCOVERY, DELIVERY SYSTEMS AND
LABORATORY DIAGNOSTICS that will be held in Bled in autumn 2011.
The Scientific Committee has made a special effort to compile a programme which
incorporates the interests and orientations expressed by participants of preceding BBBB Conferences
and include new topics at the cutting edge in the pharmaceutical sciences. This year it is the first time that
three different scientific fields are joining - Medicinal Chemistry, Pharmaceutical Technology, and Laboratory
Diagnostics. The programme of the 4th BBBB Conference is designed for researchers, pharmacists,
clinical chemists and other health allied professionals with interests in new drug design and discovery, delivery
systems and diagnostic approaches.
Plenary lectures will represent the interdisciplinary platform that put together different parts of
pharmaceutical science and will focuse on cooperative approach from diagnosis to drug therapy, through
translational medicine to safer drugs. The presenters are pioneers and opinion leaders from academia,
laboratories and pharmaceutical industry. Their lectures will provide starting-points for fruitful conference
presentations and discussions.
Drug design and discovery topics will cover natural products, design of small molecule modulators
of enzymes, receptor and transporter protein action as well as multitarget drug discovery. Progress in
kinase-selective inhibitors which are at the forefront of targeted cancer therapy will be reported. Past lessons
and future challenges in designing safer drugs in order to reduce attrition rate will be addressed.
Within manifold topics of drug delivery systems the progress in oral modified release dosage forms,
starting with polymers through theoretical view to the analysis and production, will be presented. Some
aspects on not-so-distant future drug products like design and production of biopharmaceutical nanomedicines
will be reported. Based on this reports it shall be discussed what are the nanoscience technologies
at hand for solving this challenges.
In laboratory diagnostics the new challenges in discovering and monitoring leukemias, endocrine diagnostics,
cardiovascular and other diseases will be shown. The diagnostic usefulness of new and old diagnostics
markers as well as on new strategies for the diagnostics and treatment monitoring of patients will
be adressed critically. Upon returning home the participants will be able to discuss the current advances
of diseases biomarkers used in laboratory diagnostics.
Additionally, a major goal of the Conference is to facilitate and reinforce networking between academia
and profession, and students as well. To guarantee the quality of future research and new practical
applications, exchange and discussion between experienced colleagues, young scientists and professionals
must be enthusiastically promoted.
We are cordially welcoming you in Bled!
Prof. Dr. Julijana Kristl
Prof. Dr. Janja Marc
Prof. Dr. Danijel Kikelj
For more information visit our website
www.bbbb-eufeps.org
Conference Chair
Julijana Kristl, Ljubljana, Slovenia
Founders of BBBB Conferences
Dominique Duchene, Paris, France
Istvan Hermecz, Budapest, Hungary
Hincal Atilla, Ankara, Turkey
Hans Linden (EUFEPS)
Aleš Mrhar, Ljubljana, Slovenia
Christian R. Noe, Vienna, Austria
Peep Veski, Tartu, Estonia
Scientific Committee
Karmela Barišić, Zagreb, Croatia
Ruggero Bettini, Parma, Italy
Jörg Breitkreutz, Düsseldorf, Germany
Sema Çalis, Ankara, Turkey
Gerhard Ecker, Vienna, Austria
Stanko Gobec, Ljubljana, Slovenia
Gabor L. Kovacs, Pecs, Hungary
Istvan Hermecz, Budapest, Hungary
Albin Kristl, Ljubljana, Slovenia
Gašper Marc, Ljubljana, Slovenia
Aleš Rotar, Novo mesto, Slovenia
Vojmir Urlep; Ljubljana, Slovenia
Jürgen Siepmann, Lille, France
Arto Urtti, Helsinki, Finland
Clive G. Wilson, Glasgow, UK
Peep Veski, Tartu, Estonia
Jari Yli-Kauhaluoma, Helsinki, Finland
Conference Co-chairs
Danijel Kikelj, Ljubljana, Slovenia
Janja Marc, Ljubljana, Slovenia
Organizing Committee
Saša Baumgartner (president)
Lucija Peterlin Mašič (president)
Marko Anderluh
Mateja Cegnar
Bojan Doljak
Mirjana Gašperlin
Iztok Grabnar
Janez Kerč
Nataša Karas Kuželički
Aleš Mlinarič
Irena Mlinarič Raščan
Barbara Možina
Aleš Obreza
Tomaž Vovk
Franc Vrečer
Jernej Zadnik
President of Satellite Symposium
Franc Vrečer
Scientific Committee of Satellite
Symposium
Saša Baumgartner
Sara Cesar
Jernej Zadnik
Chairs and Committees
Safety & Toxicology Plenary lectures
4 BBBB Conference:
New Trends in Drug Discovery
Delivery Systems and
Laboratory Diagnostics
Lessons in drug discovery
Welcome reception Banquet
Laboratory medicine in
21s t century
Satellite Symposium
Oral Modified Release Dosage
Forms – From Polymer to
Drug Delivery System
Laboratory medicine:
from research to practice
Challenges in drug delivery
New formulation strategies
Medicinal chemistry
in drug discovery
Morning
sessions
Afternoon
sessions
Mid-day sessions
Evening
Poster session Poster session
SCIENTIFIC PROGRAMME AT
GLANCE
THURSDAY
29 September
FRIDAY
30 September
SATURDAY
th 1 October
th
th st
Morning
Session
9:00
14:00
Opening
Oral modified release dosage forms – Quo Vadis
Revolution: The applications of new imaging and delivery
technologies in formulation prototyping
Natural polymers for oral modified release dosage forms
Modification of drug release by synthetic or
semisynthetic polymers
Single unit versus multiparticulate modified release
dosage forms
Experimental and theoretical techniques for
characterization of enteric and GIT-insoluble film coatings
Biopharmaceutical aspects of oral modified release
dosage forms
Statistical and machine learning tools in evaluation and
optimization of modified release products
Closing remarks
Franc Vrečer
University of Ljubljana and KRKA, SI
Franc Vrečer
University of Ljubljana and KRKA, SI
Saša Baumgartner
University of Ljubljana, SI
Clive Wilson
University of Glasgow, UK
Matej Pavli
KRKA, SI
Dirk Schmalz
HARKE Pharma GmbH, DE
Klara Pintye Hodi
University of Szeged, HU
Zrinka Abramovič
LEK, SI
Marija Bogataj
University of Ljubljana, SI
Svetlana Ibrić
University of Belgrade, RS
Satellite symposium:
Oral Modified Release Dosage Forms – From Polymer to Drug Delivery System
Afternoon
session
15:30
Evening
19:00
Opening
Old and new allergic diseases:
From diagnosis to drug therapy
Translational medicine: How to explain variability of in vivo
drug effects by in vitro experiments, a raloxifen case
Designing safer drugs: Past lessons and future challenges
Welcome reception
Julijana Kristl
University of Ljubljana, SI
Hans Uwe Simon
University of Bern, CH
Aleš Mrhar
University of Ljubljana, SI
Charles Scott Boyer
AstraZeneca, Mölndal, SE
Planary lectures: 4 BBBB Conference
New Trends in Drug Discovery,
Delivery Systems and Laboratory Diagnostics
th
THURSDAY 29 t h September 2011
Morning
session
1.
9:00
Treating depression: Lessons from
human lymphoblastoid cell
Advanced cell based therapies
Short communications
David Gurwitz,
Tel Aviv University, IL
Matjaž Jeras
University of Ljubljana, SI
Laboratory medicine: From research to practice
Morning
session
11.
11:10 Drug delivery in brain and spinal cord trauma model
Formulation of multiunit drug delivery systems
Short communications
Hakan Eroglu
Hacettepe University, TR
Istvan Antal
Semmelweis University, HU
Challenges in drug delivery
Mid-day
session
12:45
Poster session
Presenters are obligated to be at poster from 13:15 to 14:15
Afternoon
session
1.
14:15
New glycine transporter inhibitors:
Design, synthesis and biological evaluation
Natural product drug discovery for
Chlamydia pneumoniae
Short communications
Péter Mátyus
Semmelweis University, HU
Pia Vuorela,
Åbo Akademy University, FI
Lessons in drug discovery
Afternoon
session 11.
16:25 The modern endocrine laboratory: principles and pitfalls
Diagnosis of atherosclerotic cardiovascular disease:
Can laboratory do it better?
Short communications
Gabor L. Kovacs
University of Pecs, HU
Darko Černe
University of Ljubljana, SI
Laboratory medicine in 21 century
Evening
20:30 Banquet
FRIDAY 30t h September 2011
st
Afternoon
session
1.
14:15
Phthalates as endocrine disrupting chemicals
and pharmaceutical excipients
Short communications
Filiz Hincal
Hacettepe University,TR
Gérard Siest
University of Nancy, FR
Pharmacogenomics and drug safety
Immunogenicity of salmon fibrin glue
Ivo Laidmäe
University of Tartu, ES
Safety and toxicology
16:00 Closing remarks
* The programme is correct at the time of the printing, however, the organizers reserve the right to alter the programme if and as is deemed necessary.
SATURDAY 1s t October 2011
Morning
session
1.
9:00
Formulation of protein pharmaceuticals:
Trends, truths and surprises from the last 20 years
Preparation and stabilization of amorphous
formulations in drug development
Simultaneous topical delivery of vitamins C and E:
An opportunity for combating photoageing?
Short communications
Gerhard Winter
Ludwig Maximilians Universität
München, DE
Mirjana Gašperlin
University of Ljubljana, SI
Karin Kogermann
University of Tartu, ES
New formulation strategies
11:10
Morning
session
11.
Development of kinase-selective inhibitors:
Challenges with Pim kinases
Toward antithrombotic compounds with dual function –
recent developments and future challenges
Design of Src kinase inhibitors as a therapeutic
approach for cancer and metastases
Short communications
Janez Ilaš
University of Ljubljana, SI
Sűreyya Őlgen,
Universiyt of Ankara, TR
Medicinal chemistry in drug discovery
Mid-day
session
12:45
Poster session
Presenters are obligated to be at poster from 13:15 to 14:15
Päivi Koskinen
Turku centre for biotechnology, FI
Call for Papers / Instructions for Authors
The scientific committee find the poster session as an extremely important part of 4th
BBBB Conference. Therefore special attention will be paid to this session and all participants
are encouraged to present their work as a poster. All posters will be reviewed
by two referees and nearly 15 posters will be selected for oral presentation.
Participants are invited to submit abstract for oral or poster presentations before April
30, 2011. Abstracts can only be submitted online. Please, follow the instructions carefully
and use the following URL:
http://www.bbbb-eufeps.org/scientific-information/call-for-abstracts
All accepted extended abstracts will be published in a special
issue of European Journal of Pharmaceutical Sciences. Authors
will be notified on the acceptance of their paper and the type
of presentation (oral or poster) by June 30, 2011. The dimension
of the poster should not exceed 90 cm wide x 120 cm
high. The best three posters will be awarded.
Authors are requested to consider submitting the papers dealing
with the following Topics
• Recent strategies in drug delivery formulation: from materials to medicine
• Nanotechnology and nanotoxicity
• Translational medicine: from basic research to new diagnostic and treatment
approaches
• All aspects of medicinal chemistry including drug design, discovery and
development
• Methods, instrumentation and technologies in pharmacy and
laboratory medicine
• Genomics and proteomics in diagnosis and treatment
In you need any further information, please contact Aleš Obreza by e-mail:
ales.obreza@ffa.uni-lj.si
For more information visit our website
www.bbbb-eufeps.org
Accommodation
Secretary of the Conference
Slovenian Pharmaceutical Society - Jelka Dolinar,
Dunajska 184 A, SI-1000 Ljubljana, Slovenia
Phone: +386 1 569 26 01
Fax: +386 1 569 26 02
E-mail: jelka.dolinar@sfd.si
Prices are in EUR per day and per room including breakfast. Tourist tax is not included in the price.
Early booking is recommended!
Tourist rooms and hostels at lower rates (from 30 € per room) can be booked as well. All
hotels, tourist rooms and hostels are within the walking distance from the Conference
venue Festival Hall. Reservation of the hotel rooms should be performed via
fax: +386 45780355 or e-mail: ksenija@albatros-bled.com.
Insurance
Organizers of the 4BBBB Conference and the agency Albatros accept no liability for personal
injuries, or for less or damage to property belonging to Conference participants, incurred
during the Conference. We recommend that each participant acquire personal insurance.
Exhibition and Sponsoring
The Conference will be accompanied by exhibition of products, equipment and technologies.
We invite you to join the industrial exhibition in order to present your company and
development achievements. There are several possibilities of sponsoring this event. Any
kind of support is very appreciated. Please, download a special document for sponsorship,
exhibition and advertising conditions from symposium homepage. However, organisers
are open for any kind of other proposals and suggestions.
http://www.bbbb-eufeps.org/sponsorship-and-exhibition
Reservations and allocation of
space will be accepted on a first
come - first served basis. For information
regarding the exhibition or
sponsorship, please contact:
Registration, Transfer and Accommodation
Information can be found at:
http://www.bbbb-eufeps.org/registration-and-accommodation
Congress Registration, Transfer and Accommodation is handled
by Albatros Bled, Congress Agency and Congress Service.
Mrs. Ksenija Blazic
Ribenska 2, 4260 Bled, Slovenia
Phone: + 386 4 578 03 58d
Fax: + 386 4 578 03 55
E-mail: ksenija@albatros-bled.com
Registration Fee
Registration fee includes:
• Admission to the 4th BBBB Conference sessions
and Exhibition (Additional registration fee is
required for the Satellite symposium!)
• Book of abstracts
• Final program
• Conference bag
• Certificate of attendance
Cancellation and refunds:
Personal registration cancellation is only possible in writing before 30 August 2011. In this case
administrative costs of 50 € will be charged. After this deadline no refunding is possible. For personal
cancellation please contact Albatros Bled, ksenija@albatros-bled.com.
Payment can be made either by bank transfer or by credit card.
• Welcome reception on Thursday,
September 29, 2011
• Conference dinner on Friday,
September 30, 2011
• Coffee breaks and luncheons at the
symposium venue on Thursday and Friday
• 30€ discount for presenting (first) author of submitted abstract for early registration (before 1st August). Provide
your unique abstract submission code which was sent to you in the confirmation e-mail upon abstract submission.
• Confirmation letter signed by Dean is required
Congress venue
Congress venue will be in the Bled Festival Hall, which is located in the Center of the Bled.
The transfer from Ljubljana Airport or from Railway station Lesce will be organized
(http://www.bbbb-eufeps.org). Please, download the Registration, transfer and accommodation
form.
For additional information on registration and accommodation please contact: Albatros
Bled, Congress Agency and Congress Service, ksenija@albatros-bled.com
About Bled
Bled is a municipality in northwestern Slovenia in the region of Upper Carniola. The area
within the Julian Alps is a popular tourist destination. Bled is known for the glacial Lake Bled,
which makes it a major tourist attraction. Perched on a rock overlooking the lake is the
iconic Bled Castle. A small island in the middle of the lake is home to the Assumption of
Mary Pilgrimage Church; visitors frequently ring its bell for good luck. Human traces from
prehistory have been found on the island. The town is also known in Slovenia for its vanillaandcream pastry called kremna rezina or kremšnita. For highlights of the area please visit
www.bled.si/en/.
About Slovenia
Slovenia is the only country in Europe that combines the Alps, the Mediterranean, the Pannonian
Plain and the Karst in a beautiful, small, green package that you will be able to experience
in organised tours (link www.zidanamarela.si/BBBB): trips to Capital Ljubljana, 20-km
long Karst cave system of the Postojna Cave, unconquerable Predjama Castle, emerald
beauty of river Soča, already mentioned Triglav National Park and more together with degustation
of excellent Slovenian wines and tasty culinary specialties will make 4th BBBB
Conference unforgettable experience.
Important dates
Conference dates: 29.9. – 1.10. 2011
Satellite Symposium: 29.9. 2011
Abstract submission before: 30.4.2011
Abstract acceptance notification: 30.6.2011
Early on-line registration before: 1.8.2011
th
European Federation for
Pharmaceutical Sciences
HSPS, Hungarian Society for
Pharmaceutical Sciences, Hungary
International Federation Chemistry and Laboratory Finnish Pharmaceutical Society
Turkish Pharmacetical Technology
Scientists' Association
Organizing Societies:
As co-organizers the following associations are supporting 4 BBBB Conference:
We are very pleased that the conference is organised in partnership under the auspices of European Federation for Pharmaceutical
Sciences, European Federation of Medicinal Chemistry and International Federation of Clinical Chemistry and Laboratory Medicine:
University of Ljubljana, Faculty of SFD, Slovenian Pharmaceutical Pharmacy, Slovenia
Society, Slovenia
th
International Association for
Pharmaceutical Technology
Important addresses:
Handling of abstracts
Aleš Obreza
University of Ljubljana,
Faculty of Pharmacy
Aškrčeca cesta 7, 1000 Ljubljana, Slovenia
E-mail: ales.obreza@ffa.uni.-lj,si
Secretary of the Conference
Jelka Dolinar
Slovenian Pharmaceutical Society
Dunajska 184A, 1000 Ljubljana, Slovenia
Phone: +386 1 569 26 01, Fax: +386 1 569 26 02
E-mail: jelka.dolinar@sfd.si
Registration, transfer and accommodation
Ksenija Blazic
Albatros Bled, Congress Agency and Congress Service
Ribenska 2, 4260 Bled, Slovenia
Phone: +386 4 578 03 58, Fax: +386 4 578 03 55
E-mail: ksenija@albatros-bled.com
Estonian Academical
Society of Pharmacy
European Federation for
Pharmaceutical Sciences
HSPS, Hungarian Society for
Pharmaceutical Sciences, Hungary
International Federation of Clinical
Chemistry and Laboratory Medicine
Finnish Pharmaceutical Society
Turkish Pharmacetical Technology
Scientists' Association
International Society of Drug Delivery
Sciences and Technology
EFMC European Federation for Medicinal
Chemistry
Controlled Relese Society
Slovenia Local Chapter
For more information visit our website
www.bbbb-eufeps.org