Title: Director, Nanofabrication & Nanomaterials
Center for Advanced
Microstructures and Devices
6980 Jefferson Hwy.
Baton Rouge, LA 70806
Office Tel. : (225) 578-9320
Fax: (225) 578-6954
Academic Preparation:
Ph.D (Chemistry)
Honors and Awards
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Member, Scientific Advisory Board, Maximum Life Foundation
Nano 50 Technology Award, 2006.
Program Chair, CAMD Summer workshop on “ Nanotechnology in biology,
Biotechnology and Medicine,” 2004.
Chairman, Session on Magnetic nanoparticles for Therapy, Nanomaterials, Business
Communications., 2004.
Editor-in-Chief, Journal of Biomedical Nanotechnology, 2004-2005
Professional Media Features
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DOE EFRC Center at LSU
Nano50 Awards
LBTC Buisness Competition-NanoMAT Technologies
R&D Magazine -"Nanotechnology Takes Medical Intervention to a New Level "
LSU Research -"NANO LIFE SAVERS - New device uses nanoparticles to detect
anthrax and other biological agents"
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Innovation -"Nano Wars - Targeting Cancer Cells With Nano-Particles by Fatou
Bintou Sagnang"
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The Advocate -"CAMD puts focus on science”
Publications - Refereed Journals
1. Challa S.S.R. Kumar, Nanotechnology Tools in Pharmaceutical R&D, Materials
Today, In Press
2. Rosa T. Branca, Yuming M. Chen, Vladimir Mouraviev, Gigi Galiana, Elizabeth R.
Jenista, Challa Kumar, Carola Leuschner, and Warren S. Warren, iDQC Anisotropy
Map Imaging for Tumor Tissue Characterization In Vivo, Magnetic Resonance in
Medicine 61:937–943 (2009)
3. J. Meng, J. Fan, G. Galiana, R.T. Branca, P.L. Clasen, S. Ma, J. Zhou, C. Leuschner,
C.S.S.R. Kumar, J. Hormes, T. Otiti, A.C. Beye, M.P. Harmer, C.J. Kiely, W. Warren,
M.P. Haataja, W.O. Soboyejo, LHRH-functionalized superparamagnetic iron
oxide nanoparticles for breast cancer targeting and contrast enhancement in
MRI. Materials Science and Engineering: C ;In Press, Corrected Proof.
4. Nachal Devi Subramanian, Balaji Gopalan, Challa S.S.R. Kumar and James J. Spivey,
Development of cobalt - copper nanoparticles as catalysts for higher alcohol
synthesis from syngas, Cataysis Today, 2009 (in press)
5. Yujun Song, Josef Hormes and Challa S.S.R. Kumar, Microfluidic Synthesis of
Nanomaterials, Small, 4(6), 698-711, 2008.
6. Michelle C. Urbina, Svetlana Zinoveva, Toby Miller, Cristina M. Sabliov, William T.
Monroe, and Challa S. S. R. Kumar., Investigation of Magnetic NanoparticlePolymer Composites for Multiple-controlled Drug Delivery, J. Phys.Chem. C.,
2008, in Press
7. De Silva, Rohini M.; Palshin, Vadim; Nalin de Silva, K. M.; Henry, Laurence L.; Kumar,
Challa S. S. R.. A new role for surfactants in the formation of cobalt
nanoparticles. Journal of Materials Chemistry (2008), 18(7), 738-747.
8. Zinoveva, Svetlana; De Silva, Rohini; Louis, Russell D.; Datta, Proyag; Kumar, Challa
S. S. R.; Goettert, Jost; Hormes, Josef. The wet chemical synthesis of Co
nanoparticles in a microreactor system: A time-resolved investigation by Xray absorption spectroscopy. Nuclear Instruments & Methods in Physics Research,
Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment (2007),
582(1), 239-241.
9. Roy, Amitava; Morikawa, Eizi; Bellamy, Henry; Kumar, Challa; Goettert, Jost; Suller,
Victor; Morris, Kevin; Ederer, David; Scott, John. Status of the Center for
Advanced Microstructures and Devices (CAMD)-2007. Nuclear Instruments &
Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors, and
Associated Equipment (2007), 582(1), 22-25
10. Kumar, Challa S. S. R.; Leuschner, Carola; Urbina, Michelle; Ozkaya, Tevhida; Hormes,
Josef. Glutaric acid as a spacer facilitates improved intracellular uptake of
LHRN-SPION into human breast cancer cells. International Journal of
Nanomedicine (2007), 2(2), 175-179.
11. De Silva, Rohini M.; Palshin, Vadim; Fronczek, Frank R.; Hormes, Josef; Kumar, Challa
S. S. R.. Investigation of the Influence of Organometallic Precursors on the
Formation of Cobalt Nanoparticles. Journal of Physical Chemistry
C (2007), 111(28), 10320-10328.
12. Astete, Carlos E.; Kumar, Challa S. S. R.; Sabliov, Cristina M. Size control of
poly(D,L-lactide-co-glycolide) and poly(D,L-lactide-co-glycolide)-magnetite
nanoparticles synthesized by emulsion evaporation technique. Colloids and
Surfaces, A: Physicochemical and Engineering Aspects (2007), 299(1-3), 209-216.
13. Kizilkaya, Orhan; Ono, Masaki; Bianchetti, Chris; Kumar, Challa S. S. R.; Morikawa,
Eizi. Ultrathin film assembly of sulfobetaine-stabilized palladium
nanoparticles investigated by photoemission spectroscopy. Materials
Letters (2007), 61(7), 1533-1536.
14. Yujun Song, Hartwig Modrow, Laurence L. Henry, Cheng K. Saw, Ed E. Doomes,
Vadim Palshin, Josef Hormes and Challa S S R Kumar, Microfluidic Synthesis of
Cobalt Nanoparticles, Chem. Mater., 18 (12), 2817 -2827, 2006.
15. Carola Leuschner, Challa SSR Kumar, Zhou, Jikou, Soboyejo, Winston O, William
Hansel, and Josef Hormes, LHRH-conjugated magnetic iron oxide nanoparticles
for detection of breast cancer metastases, Breast Cancer Research and Treatment
( 2006 ), 99(2), 163-176.
16. Zhou, J.; Leuschner, C.; Kumar, C.; Hormes, J.; Soboyejo, W. O. A TEM study of
functionalized magnetic nanoparticles targeting breast cancer
cells. Materials Science & Engineering, C: Biomimetic and Supramolecular
Systems (2006), 26(8), 1451-1455.
17. Bala G. Nidumolu, Michelle C. Urbina, Josef Hormes, Challa S. S. R. Kumar, and W.
Todd Monroe, Functionalization of Gold and Glass Surfaces with Magnetic
Nanoparticles Using Biomolecular Interactions, Biotechnology Progress, 22(1), 91-95,
(2006).
18. Zhou, Jikou; Leuschner, Carola; Kumar, Challa; Hormes, Josef F.; Soboyejo, Winston
O., Sub-cellular accumulation of magnetic nanoparticles in breast tumors and
metastases., Biomaterials (2006), 27(9), 2001-2008.
19. Lu, Zonghuan; Prouty, Malcolm D.; Guo, Zhanhu; Kumar, Challa S. S. R.; Lvov, Yuri
M.. Layer-by-layer nanoengineered magnetic encapsulation system for drug
delivery. PMSE Preprints (2005), 93, 656-657.
20. J. Zhou, C. Leuschner, C. Kumar, J. Hormes and W.O. Soboyejo, A TEM study of
functionalized magnetic nanoparticles targeting breast cancer cells,
Mater.Sci.Eng C, In Press, Corrected Proof, Available online 27 September 2005.
21. Carola Leuschner, Challa SSR Kumar, William Hansel, and Josef Hormes, Targeting
breast cancer cells and their metastases through luteinizing hormone
releasing hormone (LHRH) receptors using magnetic nanoparticles,
J.Biomed.Nanotech., 1(2), 229-233, 2005.
22. Yujun Song, E. E. Doomes, John Prindle, Roland Tittsworth, Josef Hormes and Challa
SSR Kumar Investigations into Sulfobetaine-stabilized Cu Nanoparticle
Formation:Towards Development of a Micro fluidic Synthesis, J.Phys.Chem.B
109(19); 9330-9338, 2005.
23. C. Milburn,J. Zhou, O. Bravo, C. Kumar, and W. O. Soboyejo, Sensing Interactions
Between Vimentin Antibodies and Antigens for Early Cancer Detection,
J.Biomed.Nanotech. 1(1), 30-38, 2005.
24. Kumar, Challa S. S. R.. Welcome to the Journal of Biomedical
Nanotechnology. Journal of Biomedical Nanotechnology (2005), 1(1), 1-2.
25. H. Modrow, N. Palina, C.S.S.R. Kumar, E.E. Doomes, M. Aghasyan, V.Palshin, R.
Tittsworth, J.C. Jiang, J. Hormes, Characterization of size-dependent structural
and electronic properties of CTAB-stabilized cobalt nanoparticles by X-ray
absorption spectroscopy, Physica Scripta, T115, 790-793, 2005.
26. Zonghuan Lu, Malcolm D. Prouty, Zhanhu Gao, Vladimir O. Golub, Challa S.S.R. Kumar,
Yuri M. Lvov, Magnetic Switch of Permeability for Polyelectrolyte
Microcapsules Embedded with Co@Au Nanoparticles, Langmuir, 21(5), 2042 2050, 2005.
27. J. Hormes, H. Modrow, H. Bonnemann and Challa S.S.R. Kumar, Electronic,
magnetic and geometric properties of functionalized magnetic nanoparticles,
J. Appl. Phys. Lett (2005), 97(10), 10R102-10R102-6.
28. Guo, Zhanhu; Kumar, Challa S. S. R.; Henry, Laurence L.; Doomes, E. E.; Hormes,
Josef; Podlaha, Elizabeth J. Displacement Synthesis of Cu Shells Surrounding Co
Nanoparticles. Journal of the Electrochemical Society (2005), 152(1), D1-D5
29. Challa S.S.R.Kumar, Carola Leuschner, E. E. Doomes, Larry Henry, Martha Juban, and
Josef Hormes, Efficacy of lytic peptide bound magnetite nanoparticles in
destroying breast cancer cells, Journal of Nanoscience and Nanotechnology, 4 (3),
245-249, 2004.
30. Y. Song, Challa S.S.R.Kumar, and Josef Hormes, Fabrication of a SU-8 based
microfluidic reactor on a PEEK substrate sealed by a Flexible semi-solid
transfer’ (FST) process, Journal of Micromachining and Microengineering, 14, 1-9,
2004.
31. Y. Song, Challa S.S.R.Kumar, and Josef Hormes, Synthesis of Pd nanoparticles
using a continuous flow polymeric micro reactor, Journal of Nanoscience and
nanotechnology, 4(7), 788-793, 2004.
32. Ch.S.S.R.Kumar, M.Aghasyan, H. Modrow, J. Hormes, and R. Tittsworth , Gold
nanoparticles in polymer micro beads -one pot synthesis and XANES
characterization, Journal of Metastable & Nanocrystalline Materials, 23, 343-347,
2004.
33. Challa S.S.R.Kumar, Mher Aghasyan, Hartwig Modrow, Edward Doomes, Cindy
Henk ,Josef Hormes and Rolland Tittsworth, Synthesis and Characterization of SAu Interaction in Gold Nanoparticle bound Polymeric Beads, Journal of
Nanoparticle Research, 6, 369-376, 2004
34. G. Wiche, J. Gottert, Y.Song, J.Hormes and Ch.S.S.R.Kumar, Functional micro
devices using 'nanoparticle-photo resist' composites, Int. J. Comp. Eng. Sci.,
4(3), 525-528, (2003).
35. Kumar, Challa S. S. R.; Modrow, Hartwig; Hormes, Josef. Characterisation of
sonochemically produced PdO nanoparticles by X-ray absorption near edge
structure spectroscopy, Particle & Particle Systems Characterization (2002), 19(5),
336-341.
36. E. Morikawa, J.D.Scott, J. Goettert, G. Aigeldinger, C.S.S.R. Kumar, B.C. Craft,
P.T. Sprunger, R.C. Tittsworth, and F.J.Hormes, “Status of the Centre for
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Advanced Microstructures and Devices 2001”, Review of Scientific Instruments,
73,3, 2002.
Kumar, Ch S. S. R.; Nijasure, Avinash M. “Vulcanization of rubber: how to alter
molecular structure and influence physical properties”, Resonance, (1997), 2(4),
55-59.
Ch.S.S.R.Kumar, S.Malladi and S.Yakkundi, “Limonoids from the seeds of
azadirachta Indica”, Phytochemistry, 43, 2, 451-455, 1996.
Krishnaswamy, N. R.; Kumar, Ch Siva Sai Ramana. “Absorption, emission and
mass spectral characteristics of oligothiophenes and their derivatives”. Indian
Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry
(1993), 32B(7), 766-71.
Krishnaswamy, N. R.; Kumar, C. Siva Sai Ramana. “Synthesis of 2,5-dipropyl
(ii)cycloheptanol via dimethyldithienotropone” Indian Journal of Chemistry,
Section B: Organic Chemistry Including Medicinal Chemistry (1992), 31B(7), 449-51.
Krishnaswamy, N. R.; Kumar, C. Siva Sai Ramana, Prasanna, “ Photochemical
reactions of thienyl-, bithienyl-, and terthienyl methanols”, Journal of Chemical
Research (S), 166, 1991; J.Chem.Res. (M), 1801-1830, 1991.
Publications - Books and Book Chapters
1. Challa S.S.R.Kumar, Nanomaterials for Medical Applications, KirkOthmer
Encyclopedia of Chemical Engineering, John Wiley & Sons, Inc., 2007.
2. “Nanofabrication towards biomedical applications”, Editors : Challa S.S.R.Kumar,
Josef Hormes and Carola Leuschner, by Wiley-VCH 2005
3. Carola Leuschner and Challa S.S.R.Kumar, “Nanotechnology in Cancer therapy”, a
book chapter in Nanofabrication towards biomedical applications, Editors: Challa
S.S.R.Kumar, Josef Hormes and Carola Leuschner, by Wiley-VCH 2005.
4. A ten volume book series on “ Nanotechnologies for Life Sciences” being published
by Wiley-VCH 2005-2006, Editor : Challa S.S.R.Kumar. [http://www.wileyvch.de/books/info/ntls/ ]
Patents
1. Kumar, Challa S. S. R.; De Silva, Rohini M.; Hormes, Josef. Method for making
cobalt nanomaterials. PCT Int. Appl. (2008), 24pp. CODEN: PIXXD2 WO
2008034062 A2 20080320 AN 2008:353358.
2. Leuschner, Carola; Lvov, Yuri M.; Kumar, Challa S. S. R.. Layered nanoparticles for
self-aggregation prevention and sustained release of small molecule drugs
such as ligand-lytic peptide conjugates for cancer targeting. PCT Int. Appl.
(2007), 47pp. CODEN: PIXXD2 WO 2007115033
3. Leuschner, Carola; Kumar, Challa S. S. R.; Hansel, William; Hormes, Josef. In vivo
imaging and therapy with magnetic nanoparticle conjugates. PCT Int.
Appl. (2007),
79pp. WO 2007021621.
4. Kumar, Challa; Podlaha, Elizabeth J.; Guo, Zhanhu; Hormes, Josef. Core-shell
nanostructures and microstructures. U.S. Pat. Appl.
Publ. (2006),
24pp. US 2006177660.
5. Song, Yujun; Kumar, Challa; Hormes, Josef. Fabrication of a completely
polymeric microfluidic reactor for chemical synthesis. U.S. Pat. Appl.
Publ. (2006),
19 pp. US 2006014271.
6. Singh, Anil Kumar; Kumar, Challa Siva Sai Raman; Achar, Sudhir. Process for the
preparation of polymers from vinylic monomers using tetraethylthiuram
monosulfide as photoinitiator. Indian Pat.
Appl. (2005),
13pp. IN 2000MU00638.
7. Kumar, Challa Siva Sai Ramana; Salunkhe, Ranjan Vaman. A process for the
preparation of acetonyl N,N-diethyldithiocarbamate via the UV irradiation of
tetraethylthiuram monosulfide in acetone. Indian (1999),
11
pp. IN 182660.
8. Ravindranath, Bhagavathula; Thejavathi, Renukappa; Kumar, Challa Siva Sai Ramana;
Yakkundi, Shirish Ranganath. Chromatographic method and its use for
separation of azadirachtin. Can. Pat. Appl. (1997),
26 pp. CA 2184564.