Invited speakers:
Prof. dr. Wolfgang A. Linke
Department for Cardiovascular Physiology, Ruhr University Bochum, Bochum, Germany
Dr. Reinier A. Boon
“Aging and Cardiovascular Disease: The role of microRNAs"
The Institute for Cardiovascular Regeneration, University of Frankfurt in Germany
Dr. Geerten P. van Nieuw Amerongen
Department of Physiology, Institute for Cardiovascular research, VU University Medical Center, Amsterdam
Drs. Jan Groothuis
Department of Cardiology, Institute for Cardiovascular research, VU University Medical Center, Amsterdam
Selected Oral presentations:
Right ventricular myoglobin decrease in human pulmonary hypertension
G Ruiter1,2, YY Wong1,2, FS de Man1, PE Postmus1, N Westerhof2, HWM Niessen3, WJ van der Laarse2,
A Vonk-Noordegraaf1
Departments of 1Pulmonology, 2Physiology, and 3Pathology, Institute for cardiovascular research, VU University
Medical Center, Amsterdam, The Netherlands.
Diverse effects of exercise on myofilament function in pathologic left ventricular hypertrophy and
dysfunction
Elza D. van Deel1, Martine de Boer1, Nicky M. Boontje2, Monique de Waard1, Jolanda van der Velden2,
Dirk J. Duncker1
1
Experimental Cardiology, Thoraxcenter, Cardiovascular Research School COEUR, Erasmus MC, University
Medical Centre Rotterdam, Rotterdam, 2Laboratory for Physiology, Institute for cardiovascular research, VU
University Medical Centre, Amsterdam, The Netherlands
Transcript Analysis of a Novel Long Non-coding RNA Associated with the Pregnancy-related
HELLP-syndrome.
Marie van Dijk1, and Cees B.M. Oudejans1.
1
Department of Clinical Chemistry, VU University Medical Center, Amsterdam, The Netherlands.
Muscle Perivascular Adipose Tissue induces insulin-mediated vasodilation through the secretion of
adiponectin in lean mice
R.I. Meijer1,2*, W. Bakker1*, C.A.F. Alta1, P. Sipkema1, C.D.A. Stehouwer3, J.S. Yudkin1, E.H. Serne2,
Y.M. Smulders2, E.C. Eringa1.
* Both authors contributed equally, 1 Department of Internal Medicine, VU University medical center, Amsterdam,
The Netherlands, 2 Laboratory for Physiology, VU University medical center, Amsterdam, The Netherlands, 3
Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands
1
Posters:
(Numbers are corresponding to poster board numbering.)
Improvement of Cardiac Function in Heart Failure
Posters:
(Numbers are corresponding to poster board numbering and page of abstractbook.)
Improvement of Cardiac Function in Heart Failure
22. Low vitamin D status is associated with higher left ventricular mass in subjects with lower kidney
function and in subjects without prior cardiovascular diseases.
A.J. van Ballegooijen1, M.B. Snijder2, M. Visser1,3 K. van den Hurk3, O. Kamp4, J.M. Dekker3, G.
Nijpels5, C.D.A. Stehouwer6, R.M.A. Henry6, W.J. Paulus7, I.A. Brouwer1
1
Departement of Health Sciences and the EMGO + Institute for Health and Care Research, Faculty of Earth and Life
Sciences, VU University Amsterdam, the Netherlands 2Department of Public Health, AMC-UVA, the Netherlands 3
Department of Epidemiology and Biostatistics and the EMGO+ Institute for Health and Care Research, VU
University Medical Center, Amsterdam, the Netherlands 4Department of Cardiology, VU University Medical
Center, Amsterdam, the Netherlands 5 Department of General Practice, VU Medical Center, Amsterdam, the
Netherlands 6Department of Internal Medicine and Cardiovascular Research Institute Maastricht (CARIM),
Maastricht University Medical Centre, Maastricht, The Netherlands 7Department of Physiology, VU University
Medical Center, Amsterdam, the Netherlands.
23. The prevalence of left ventricular crypts in a large group of asymptomatic HCM mutation
carriers.
WP Brouwer1,4, MC Head1, T Germans1, AC Houweling2, K de Boer1, AM Beek1, J van der Velden3, AC
van Rossum1,4
1
Department of Cardiology, 2 Department of Clinical Genetics and Human Genetics, 3 Department of Physiology,
VU University Medical Center Amsterdam 4 Interuniversity Cardiology Institute of the Netherlands (ICIN),
Utrecht, The Netherlands
24. The effect of inhibition of the Na+/H+ exchanger on the development of hypertrophy in
hypertrophic cardiomyopathy
WP Brouwer1,6, AC Houweling2, MGJ Nederhoff3,6, T Germans1, MMGJ van Borren4, G Pasterkamp3, J
vd Velden5, AC van Rossum1,6
1
Department of Cardiology, 2 Department of Clinical Genetics and Human Genetics, VU University Medical Center
Amsterdam 3 Department of Cardiology, University Medical Center Utrecht, 4 Laboratory of Clinical Chemistry and
Haematology, Jeroen Bosch Hospital ‘s-Hertogenbosch, 5 Department of Physiology, VU University Medical
Center Amsterdam, 6 Interuniversity Cardiology Institute of the Netherlands (ICIN), Utrecht, the Netherlands.
25. Diastolic dysfunction in idiopathic Pulmonary Arterial Hypertension
S. Rain1, T. Kind1, M.L. Handoko1, B. Boerrigter1, N. Westerhof1, J. van der Velden1, A. VonkNoordegraaf1, F.S. de Man1
1
Institute for cardiovascular research, VU University Medical Center, Amsterdam, The Netherlands
26. Pulmonary artery pressure and heart rate relate with myocardial oxygen consumption in the
hypertrophied right ventricle in pulmonary hypertension
YY Wong1,2, M Lubberink3, G Ruiter1,2, PGHM Raijmakers3, P Knaapen4, WJ van der Laarse2, N
Westerhof2, A Vonk-Noordegraaf1
Departments of 1Pulmonology, 2Physiology, 3Nuclear Medicine and PET-Research, and 4Cardiology, Institute of
Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands.
27. Underfilling of the right atrium is an important mechanism of the hemodynamic impairment in
chronic obstructive pulmonary disease.
Bart Boerrigter1, Herman Groepenhoff1, Frank Helderman2, Harm-Jan Bogaard1, Nico Westerhof1,3 and
Anton Vonk-Noordegraaf1
Departments of 1Pulmonary Diseases, 2Physics and Medical Technology and 3Physiology, Institute for
Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands.
2
28. Molecular effects of the amino acid exchange R20C of cardiac Troponin I, linked to familial
hypertrophic cardiomyopathy (FHC)
Martina Saes1, Andreas Mügge1, Kornelia Jaquet1
1
Kliniken der Ruhr-Universität Bochum, St. Josef Hospital/Bergmannsheil, Bochum, Germany
29. Increased cardiomyocyte stiffness in cardio-renal disease
N. Hamdani1, M.K. Szymanski2, R.G. Schoemaker1,2, J. van der Velden1
1
Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam,
Department of Experimental Cardiology2, University Medical Center Groningen, Groningen, The Netherlands
30. Cyclic GMP Enhancing Therapy Promotes Titin Phosphorylation and Corrects High
Cardiomyocyte Passive Stiffness in Diastolic Heart Failure
Nazha Hamdani1, Jolanda van der Velden2, Ger JM Stienen2, Margaret M. Redfield3, Wolfgang A.
Linke1
1
Ruhr University Bochum, Bochum, Germany; 2ICaR-VU, Amsterdam, The Netherlands; 3Mayo Clinic, Rochester
MN.
31. Phosphorylation of HCM-inducing cTnI-R145G and its consequences in ventricular cardiac
myocytes.
Philip Steinwascher1, Sebastian Preilowski1, Nazha Hamdani2, Kornelia Jaquet1, and Andreas Mügge1
Research Laboratory Molecular Cardiology, Medical Clinics II – Cardiology, St. Josef Hospital & BG
Bergmannsheil, Clinics of the Ruhr-University, Bochum, Germany; 2Institute for Physiology, Department for
Cardiovascular Physiology, Ruhr-University, Bochum, Germany.
1
32. Impact of the cTnI-K206Q Mutation on Troponin Interaction with the Thin Filament.
Diana Kindsvater1, Martina Saes1, Ingo Morano2 and Kornelia Jaquet1
1
Res. Lab. Molecular Cardiology, Heart- and Circulation Center at the Medical Faculty, Ruhr-University Bochum,
Germany and 2Max Delbrück Center Berlin, Germany
33. Sarcomeric protein phosphorylation in hypertrophic cardiomyopathy
Diederik W.D. Kuster1, Ruud Zaremba1 and Jolanda van der Velden1
1
Dept of Physiology, Institute for cardiovascular research, VU University Medical Center, Amsterdam, The
Netherlands.
34. Altered length-dependent activation in human hypertrophic cardiomyopathy
Sabine J van Dijk,1 Rosalie Paalberends,1 Aref Najafi,1 Michelle Michels,2 Sakthivel Sadayappan,3
Nicky M Boontje,1 Dennis Dooijes,4 Cris dos Remedios,5 Folkert J ten Cate, PhD,2 Ger JM Stienen,1
Jolanda van der Velden1
1
Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, the
Netherlands; 2Thorax Center, Erasmus Medical Center Rotterdam, the Netherlands; 3Department of Cell and
Molecular Physiology, Loyola University Chicago, USA, 4Clinical Genetics, Medical Center Utrecht, the
Netherlands; 4Muscle Research Unit, Institute for Biomedical Research, The University of Sydney, Sydney,
Australia
35. Regulation of myofilament Ca2+-sensitivity in human cardiomyocytes via mono- and bisphosphorylation of the protein kinase A sites of cardiac troponin I
Paul J.M. Wijnker1, D. Brian Foster2, Anne M. Murphy2, Ger J.M. Stienen1 and Jolanda van der Velden1
1
Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The
Netherlands. 2Department of Pediatrics/Division of Cardiology, Johns Hopkins University School of Medicine,
Ross Bldg 1144/720 Rutland Avenue, Baltimore, MD 21205, USA.
36. Increased expression of different NOX proteins in diseased human aortic heart valves
Nynke E. Hahn 1,4, Alexander B.A. Vonk3,4, Tsukasa Kawahara5, Victor W.M. van Hinsbergh2,4, Christof
Meischl 1,4, Hans W.M. Niessen 1,3,4, Paul A.J. Krijnen 1,4
1
Department of Pathology, 2Physiology and 3Cardiac Surgery, VU University Medical Center, Amsterdam, The
Netherlands. 4Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands.
5
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322
3
37. The post-MI mouse heart is hypothyroid
Christine J. Pol1, Alice Muller1, Marian J. Zuidwijk1, Elza D. van Deel2, Ellen Kaptein3, Alessandro
Saba4, Maja Marchini5, Riccardo Zucchi5, Theo J. Visser3, Walter J Paulus1, Dirk J Duncker2, and
Warner S. Simonides1.
1
Laboratory for Physiology, Institute for cardiovascular research, VU University Medical Center, Amsterdam,
Experimental Cardiology, Thoraxcenter, 3Department of Internal Medicine, Erasmus University Medical Center,
Rotterdam, The Netherlands, 4Dipartimento di Chimica e Chimica Industriale, 5Dipartimento di Scienze dell’Uomo
e dell’Ambiente, University of Pisa, Italy.
2
38. Impaired myocardial perfusion on CMR is associated with increased numbers of classical
monocytes in STEMI patients treated by primary PCI.
L.F.H.J. Robbers MD1,3, A. van der Laan MD2,3, R. Nijveldt MD PhD1, A.M. Beek MD PhD1, R. Delewi
MD2,3, A. Hirsch MD PhD2, C.E. van der Schoot MD PhD5, B.J. Biemond MD PhD6, F. Zijlstra MD
PhD4, J.J. Piek MD PhD2 & A.C. van Rossum MD PhD1.
1
Dept. of Cardiology, VU University Medical Center, Amsterdam, the Netherlands. 2Dept. of Cardiology,
Academic Medical Center, the Netherlands. 3ICIN, Utrecht, the Netherlands. 4Dept. of Cardiology, University
Medical Center Groningen, Groningen, the Netherlands. 5 Dept. of Experimental Immunohematology, Sanquin
Research and Landsteiner Laboratory, Amsterdam, The Netherlands 6 Dept. of Hematology, Academic Medical
Center, Amsterdam, The Netherlands.
39. Defining the Normal Limits of Myocardial Blood Flow in Patients Evaluated for Coronary Artery
Disease by Means of Quantitative [15O]H2O PET: impact of Gender and Risk Factors
Ibrahim Danad1, Pieter G. Raijmakers2, Yolande E. Appelman1, Hans J. Harms2, Stefan de Haan1,
Mijntje L.P. van den Oever3, Cornelis van Kuijk3, Cornelis P. Allaart1, Otto S. Hoekstra2, Adriaan A.
Lammertsma2, Mark Lubberink, 2, Albert C. van Rossum1 and Paul Knaapen1.
Departments of Cardiology1, Nuclear Medicine & PET Research2 and Radiology3, VU University Medical Centre,
Amsterdam, the Netherlands.
40. Quantitative relationship between coronary calcium score and hyperaemic myocardial blood flow
as assessed by hybrid [15O]PET/CT imaging in patients evaluated for coronary artery disease.
Ibrahim Danad1, Pieter G. Raijmakers2, Yolande E. Appelman1, Hans J. Harms2, Stefan de Haan1,
Mijntje L.P. van den Oever3, Cornelis van Kuijk3, Cornelis P. Allaart1, Otto S. Hoekstra2, Adriaan A.
Lammertsma2, Mark Lubberink, 2, Albert C. van Rossum1 and Paul Knaapen1.
Departments of Cardiology1, Nuclear Medicine & PET Research2 and Radiology3, VU University Medical Centre,
Amsterdam, the Netherlands.
41. Persistent C1-inhibitor treatment in rat burn wound model: Improved healing locally in burn
wounds and systemically reduced myocardial inflammation
Begieneman, M.P.V.1,2,3, Kubat, B.2, Ullrich, M.W.4,5, Hahn, N.1,3, Stumpf, Y.1, Tempelaars, M.1,
Middelkoop, E.4,5, Zeerleder, S.6, Wouters, D.6, Ham van, M.6, Niessen, H.W.M.1,3, Krijnen, P.A.J.1,3
Departments of Pathology1, Plastic Surgery5, VU Medical Center, Amsterdam, the Netherlands. Dutch Forensic
Institute2, The Hague, the Netherlands. ICaR-VU3, Amsterdam, the Netherlands. Burnwound Center4, Beverwijk,
The Netherlands. Sanguin Research at CLB6, Amsterdam, The Netherlands
42. Effect of additional treatment with EXenatide in patients with an Acute Myocardial Infarction: the
EXAMI trial
M. Scholte, MD, L. Timmers, MD, PhD, R.N. Denham, MD, A.M. Beek, MD, PhD, O. Kamp, MD,
PhD, M. Diamant, MD, PhD, A.J.G. Horrevoets, PhD, H.W.M. Niessen, MD, PhD, W.J.Y. Chen, MD,
A.C. v Rossum, MD, PhD, Y. Appelman, MD, PhD.
1
Dept. of Cardiology, VU University Medical Center, Amsterdam, 2Dept. of Cardiology, University Medical Center
Utrecht, Utrecht, 3Dept. of Internal Medicine and Diabetes Center, VU University Medical Center, Amsterdam,
4
Dept. of Molecular Cell Biology and Imunology, VU University Medical Center, Amsterdam, 5Dept. of Pathology,
VU University Medical Center, Amsterdam
43. Human Platelet Lysate as a Fetal Bovine Serum Substitute Improves Human Adipose Derived
Stem Cell Culture for Cardiac Repair
4
BA. Naaijkens1,9,10,12, HWM. Niessen1,2,10, HJ. Prins3,4,11, PAJ. Krijnen1,10, TJA. Kokhuis8,9,12, N. de
Jong8,9, VWM. van Hinsbergh5,10,RJP. Musters5,10, O. Kamp7,9, MN. Helder6,11, A. van Dijk1,10,12, LJM.
Juffermans5,9,10,12
Departments of 1Pathology, 2Cardiac Surgery, 3Oral Cell Biology, 4Oral & Maxillofacial Surgery, 5Physiology,
6
Orthopaedics and 7Cardiology, VU University Medical Center, Amsterdam, The Netherlands. Dept of
8
Biomedical Engineering, Erasmus MC, Rotterdam, The Netherlands.9Interuniversity Cardiology Institute of the
Netherlands (ICIN), Utrecht, The Netherlands.10Institute of Cardiovascular Research (ICaR-VU), VU University
Medical Center, Amsterdam, The Netherlands.11Research Institute MOVE, Amsterdam, The Netherlands,
12
Technology Foundation STW, Utrecht, The Netherlands.
Improvement of Vascular Function in Metabolic Diseases
44. Direct measurement of stroke volume variations is not correlated with systolic or pulse pressure
variations in the rat during vena cava occlusion
Lonneke Smeding,1,3 Martin C.J. Kneyber,1,3,4 Frans B. Plötz.5 A.B. Johan Groeneveld 2,3
Departments of 1Pediatric Intensive Care and 2Intensive Care, 3Institute for Cardiovascular Research, VU
University Medical Center, Amsterdam, The Netherlands, 4Department of Pediatric Intensive Care, Beatrix
Children’s Hospital/University Medical Center, Groningen, The Netherlands, 5Department of Pediatric Intensive
Care, ErasmusMC-Sophia Children’s Hospital, Rotterdam, The Netherlands
45. Determinants of outcome in non-septic critically ill patients with acute kidney injury on continuous
venovenous hemofiltration.
Mark V Koning,1 Lianne Roest1, Mark G Vervloet2, AB Johan Groeneveld1 and Shaikh A Nurmohamed2.
1
Department of Intensive Care, VU University Medical Center, Amsterdam, The Netherlands. 2Department of
Nephrology, VU University Medical Center, Amsterdam, The Netherlands.
46. Delivered dose of continuous venovenous hemofiltration predicts outcome in septic patients with
acute kidney injury: a retrospective study.
Shaikh A Nurmohamed1, Mark V Koning,2 Mark G Vervloet1 and AB Johan Groeneveld2
1
Department of Nephrology, VU University Medical Center, Amsterdam, The Netherlands. 2Department of
Intensive Care, VU University Medical Center, Amsterdam, The Netherlands.
47. A new method for the quantification of de novo arginine
[2H3-methyl-1-13C]-methionine fed HUVECs by HPLC-MS-MS
Mariska Davids1,2, Eliane Swieringa1, Desiree Smith1, and Tom Teerlink1,2.
methylation
in
1
Metabolic Unit of the Department of Clinical Chemistry, VU University Medical Center, Amsterdam, The
Netherlands. 2Institute for Cardiovascular Research (ICaR-VU), VU University Medical Center, Amsterdam, The
Netherlands.
48. The anticancer drug imatinib protects against endothelial barrier dysfunction.
Jurjan Aman, Jan van Bezu, Amin Damanafshan, Victor W.M. van Hinsbergh and Geerten P. van Nieuw
Amerongen.
Department of Physiology, ICaR-VU, VU University Medical Centre, Amsterdam, The Netherlands.
49. ROCK2 is the primary Rho kinase involved in thrombin-induced vascular permeability
through regulation of baseline cellular tension/contractile forces
Beckers C.M.L. 1a, Knezevic N. 2a, Krishnan R. 3, Rajendran K. 3, Van Bezu J. 1, Van Hinsbergh V.W.M.
1
, Mehta D. 2, Van Nieuw Amerongen G.P. 1
1
Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, van der
Boechorstraat 7, 1081BT Amsterdam, The Netherlands. 2Department of Pharmacology, Center for Lung and
Vascular Biology, University of Illinois, College of Medicine, Chicago, IL 60612. 3Molecular and Integrative
Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA
a
Both authors contributed equally;
50. Electric cell-substrate impedance sensing on three-dimensional endothelial cell cultures with
varying substrate stiffness
5
Robert Szulcek1, Jan van Bezu2, Victor W.M. van Hinsbergh2, Anton Vonk-Noordegraaf1, and Geerten P.
van Nieuw Amerongen2.
Department of 1Pulmonology and 2Physiology, 1, 2Institute for Cardiovascular Research (ICaR-VU), VU University
Medical Center, Amsterdam, The Netherlands.
51. microRNAs control brain endothelial cell barrier function.
Arie Reijerkerk1, Bert van het Hof1, Kim A.M. Lakeman1, Joost Drexhage1, Joost B. Vos1, Martijn E.
Blommaart1, Dirk Geerts2, Reuven Agami3, Alex Prat4, Anton J. van Zonneveld5, Anton. J.G.
Horrevoets1,6 and Helga E. de Vries1.
1
Blood-Brain Barrier Research Group, Molecular Cell Biology and Immunology, VU Medical Center Amsterdam.
Department of Human Genetics, Academic Medical Center, University of Amsterdam, Amsterdam. 3Division of
Gene Regulation, The Netherlands Cancer Institute, Amsterdam. 4Neuroimmunology Research Laboratory, Center
of Excellence in Neuromics, CHUM-Notre-Dame Hospital, Faculty of Medicine, Université de Montréal, Montréal,
Quebec, Canada. 5Department of Nephrology and Einthoven Laboratory for Experimental Vascular Research,
Leiden University Medical Center, Leiden. 6Institute for cardiovascular research, VUmc, Amsterdam, The
Netherlands.
2
52. Galectin-2 Expression is Dependent on the rs7291467 Single Nucleotide Polymorphism and
Inhibits Collateral Artery Growth in mice
Anja M. van der Laan1, Stephan H Schirmer1,Oscar Volger2, Margreet de Vries3, Jasper de Koning2,
Josefien M Baggen2, Joost O Fledderus1, Reina Mebius2, Tineke CTM van der Pouw Kraan2, Paul HA
Quax3, Jan J Piek1, Anton JG Horrevoets2 and Niels van Royen2.
1
AMC, Amsterdam, 2 Institute for cardiovascular research, VUmc, Amsterdam, 3Vascular Medicine, LUMC,
Leiden.
53. Palmitic acid promotes pro-oxidant mitochondrial adaptor protein p66Shc expression in
proangiogenic cells
Julie Favre1, Ruud D Fontijn1, Tineke CTM van der Pouw-Kraan1, Anton JG Horrevoets1 .
1
Department of Molecular Cell Biology and Immunology, Institute for cardiovascular research, VU University
Medical Center, Amsterdam, The Netherlands.
54. Expression of a Retinoic Acid signature in circulating CD34+ cells from Coronary Artery Disease
Patients
Tineke CTM van der Pouw Kraan1, Stephan H. Schirmer2,5, Joost O. Fledderus3, Perry D. Moerland4,
Josefien M. Baggen1, Thomas A. Leyen1, Anja M. van der Laan2, Jan J. Piek2, Niels van Royen2, Anton
J.G. Horrevoets1
1
Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam.
Department of Cardiology, 3Department of Medical Biochemistry, 4Bioinformatics Laboratory, Department of
Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam,
Amsterdam, The Netherlands. 5Klinik für Innere Medizin III (Kardiologie, Angiologie und Internistische
Intensivmedizin), Universitätsklinikum des Saarlandes, Germany
2
55. Immune modulation by KLF2 to improve collateral artery development
Cansu Yıldırım1, Tineke C.T.M. van der Pouw-Kraan1, Josefien M. Baggen1, Ruud D. Fontijn1, Anja M.
van der Laan2, Niels van Royen2, and Anton J.G. Horrevoets1.
1
2
Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam,
Department of Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam.
56. KLF2-induced endothelial shear fibers are essential for the anti-inflammatory effects of shear flow.
Thomas Leyen1, Reinier A. Boon3, Ruud D. Fontijn1, Geerten P. van Nieuw Amerongen2 and Anton J.G.
Horrevoets1.
Departments of 1Molecular Cell Biology and Immunology and 2Physiology, VUmc, Amsterdam, 3Institute for
Cardiovascular Regeneration, Frankfurt, Germany.
57. Reference values for short-term heart rate variability in young and middle aged adults
S.W.M. Keet, C.S.E. Bulte, R.P. Garnier, C. Boer, R.A. Bouwman
Department of Anesthesiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam,
The Netherlands.
6
58. Myocardial contrast echocardiography for the study of perioperative myocardial perfusion
Carolien S.E. Bulte1,2, Jeroen Slikkerveer1,3, Otto Kamp1,3, Stephan A. Loer2, Christa Boer1,2 and R.
Arthur Bouwman1,2
1
Institute for cardiovascular research, VU University Medical Center, Amsterdam, The Netherlands. Departments
of 2Anesthesiology and 3Cardiology, VU University Medical Center, Amsterdam, The Netherlands.
59. Pulsatile flow during cardiopulmonary bypass preserves postoperative microcirculatory perfusion
Koning N.J.1,2, Vonk A.B.A.1, Verkaik M.2, Van Barneveld L.J.1, Beishuizen A.3, Atasever B.1, Van Den
Brom C.E.2, Boer C.2
Depts. Of Cardio-thoracic surgery1, Anesthesiology2 and Intensive Care3, Institute for Cardiovascular Research, VU
University Medical Center Amsterdam
60. Fresh frozen plasma administration during cardiac surgery more effectively improves hemostasis
when combined with platelet concentrate
Michael I. Meesters1, Marly Appelman1, Johannes W.A. Romijn1, Alexander B.A. Vonk2 and Christa
Boer2.
Departments of 1Anesthesiology and 2Cardio-thoracic Surgery, Institute for Cardiovascular Research, VU
University Medical Center, Amsterdam, The Netherlands.
61. The comparability of a non-invasive continuous finger blood pressure measurement device with
intra-arterial blood pressure measurements in children
Robert P. Garnier,1 Anna G.E. van der Spoel,1 Renata Sibarani-Ponsen,1 Dick G. Markhorst,2 Christa
Boer1
1
Departments of Anesthesiology and 2Pediatric Intensive Care, Institute for Cardiovascular Research, VU
University Medical Center, Amsterdam, The Netherlands
62. Decreased cardiovascular disease incidence in RA patients receiving TNF-blocking therapy:
results from two prospective cohort studies
Visman IM1, van Sijl AM1 2, Peters MJL2, Dijkmans BAC1 2, Nurmohamed MT1 2
¹ Department of Rheumatology, Jan van Breemen Institute, Amsterdam, the Netherlands
² Department of Rheumatology, VU University medical centre, Amsterdam, the Netherlands
63. Valsartan induced improvement of insulin sensitivity was not associated with improved
microvascular function in subjects with impaired glucose metabolism.
C.C.M. Moors 1, N.J. van der Zijl 2, G.H. Goossens 1, R.G. IJzerman, E.E. Blaak 1, M. Diamant2, E.H.
Serné2
1
Maastricht University, Maastricht, the Netherlands; 2Institute for Cardiovascular Research, VU University Medical
Centre, Amsterdam, the Netherlands;
64. A Multi-Centre Study on the Reliability of Qualitative and Quantitative Nailfold
Videocapillaroscopy Assessment
Herman MA Hofstee1, Erik H Serné1, Chris Roberts2, Roger Hesselstrand3, Agneta Scheja3, Tonia
Moore2, Marie Wildt3, Joanne Manning2, Alexandre Voskuyl1, Anton Vonk Noordegraaf1, Ariane
Herrick2.
1
Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands. 2The
University of Manchester, Manchester, United Kingdom. 3Lund Univeristy, Lund, Sweden.
65. Renal dysfunction in rheumatoid arthritis is associated with incident cardiovascular disease,
independently of traditional risk factors: the CARRE study
Van Sijl AM1 2, Visman IM1, van den Oever, IAM1, Peters MJL3, Voskuyl AE2, Dijkmans BAC1 2,
Nurmohamed MT1 2 3
¹ Department of Rheumatology, Jan van Breemen Institute, Amsterdam, the Netherlands
² Department of Rheumatology, VU University medical centre, Amsterdam, the Netherlands
³ Department of Internal Medicine, VU medical centre, Amsterdam, the Netherlands
66. Lipid changes in response to TNF-alpha blocking agents:
7
A Systematic Review and Meta-Analysis van Sijl AM1, Peters MJL2, Knol DL3, de Vet HC3, Sattar N4, Smulders YM2, Dijkmans BAC1,
Nurmohamed MT1 2
1
Dept. of Rheumatology, VU University Medical Center, Amsterdam, the Netherlands. 2 Dept. of Internal Medicine
and the institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands.3 Dept.
Of Epidemiology and Biostatistics, EMGO-institute, VU University Medical Center, the Netherlands. 4 BHF
Glasgow Cardiovascular Research Centre, University of Glasgow, Scotland, UK. 5 Dept. of Internal Medicine and
the institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
67. Effect of Trans Fatty Acid Consumption on Markers of Inflammation and Oxidative Stress in
Humans, a Randomized Cross-Over Study.
Liesbeth A. Smit1, Martijn B. Katan1, Anne J. Wanders2, Samar Basu3, Ingeborg A. Brouwer1
1
Department of Health Sciences and the EMGO Institute for Health and Care Research, Faculty of Earth and Life
Sciences, VU University Amsterdam, The Netherlands.
2
Division of Human Nutrition, Wageningen University, The Netherlands.
3
Oxidative Stress and Inflammation, Department of Public Health and Caring Sciences, Faculty of Medicine,
Uppsala University, Uppsala, Sweden.
68. Sunitinib-induced capillary rarefaction is directly associated with increased blood pressure – a
reversible phenomenon
Michiel P. de Boer1#, Astrid A. M. van der Veldt2#, Epie Boven2, Etto C. Eringa3, Alfons J. M. van den
Eertwegh2, Victor W.M. van Hinsbergh3, Yvo M. Smulders1, Erik H. Serné1
Departments of Internal Medicine1, Medical Oncology2, and Physiology3, Institute for Cardiovascular Research,
VU University Medical Center, Amsterdam, The Netherlands
69. Perivascular adipose tissue as a regulator of insulin-mediated microvascular recruitment: the roles
of adiponectin and AMPK.
Etto C. Eringa1, Rick I. Meijer2, Caro-lynn A. Alta1, Yvo M. Smulders2, Erik H. Serné2, John S. Yudkin2,
Coen D.A. Stehouwer3, Eugene J. Barrett4, Benoit Viollet5, Victor W.H. van Hinsbergh1.
1
Department of Physiology and 2Internal Medicine, Institute for Cardiovascular Research, VU University Medical
Centre, Amsterdam; 3Department of Internal Medicine, University of Maastricht; 4Department of Endocrinology,
University of Virginia, USA; 5Université Paris Descartes, Paris, France.
ce.
8