Provided by:
Target Audience
This program has been designed for departmental/institutional faculty, fellows, residents, medical students, nurses, community physicians, and other health professionals in the medical specialties of cardiovascular medicine, endocrinology diabetes & metabolism, gastroenterology, general internal medicine, geriatrics, hematology/oncology, infectious disease, pulmonary, allergy & critical care, renalelectrolyte & hypertension, rheumatology, sleep medicine, translation medicine and human genetics.
Educational Objectives
After completing this activity, participants should be able to:

Learn from master clinicians about clinical problem-solving techniques

Review topics of important ethical or public policy implications

Discuss the latest advances in basic research as they relate to various clinical diseases

Discuss new treatment modalities for all types of diseases in internal medicine

Improve understanding of the pathogenesis of disease to be better able to identify adverse drug events and treatment complications
Accreditation
The Perelman School of Medicine at the University of Pennsylvania is accredited by the Accreditation
Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Designation of Credit
The Perelman School of Medicine at the University of Pennsylvania designates this live activity for a maximum of 1 AMA PRA Category 1 Credit ™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Acknowledgement of Commercial Support*
NONE
For more information, please contact
Denise Arnieri
215-662-3924
Denise.Arnieri@uphs.upenn.edu

Disclosure of Relevant Financial Relationships and Unapproved Uses of Products
It is policy at the Perelman School of Medicine at the University of Pennsylvania for individuals who are in a position to control the content of an educational activity to disclose to the learners all relevant financial relationships that they have with any commercial interest that provides products or services that may be relevant to the content of this continuing medical education activity. For this purpose we consider relationships of the person involved in the CME activity to include financial relationships of a spouse or partner.
The intent of this policy is not to prevent expert faculty with relevant relationship(s) with commercial interest(s) from involvement in CME, but rather to ensure that Penn CME-certified activities promote quality and safety, are effective in improving medical practice, are based on valid content, and are independent of control from commercial interests and free of commercial bias. Peer review of all content was conducted for all faculty presentations whose disclosure information provided to the Penn Office of CME was found to contain relationships that created a conflict of interest relative to the topic of their presentation. In addition, all faculty were instructed to provide balanced, scientifically rigorous and evidence-based presentations.
The staff in the Office of CME at the Perelman School of Medicine at the University of Pennsylvania, Mila Kostic,
Director of CME and the peer reviewer Zalman Agus, MD, Associate Dean for CME, have disclosed that they have
no relevant financial relationships with any commercial interests related to the content of this educational activity.
The following individuals have disclosed that they have no relevant financial relationships with any commercial interests related to the content of this educational activity:
P LANNING C OMMITTEE M EMBER N AME
L ISA M.
B ELLINI , MD
D ANIEL K ISS , MD
P RESENTER N AME
M
L
ICHAEL
ESLIE S
S.
P ARMACEK
TEWART , MD
, MD H
E
ANNY
LAINA
A
T
L -S AMKARI
ULLY , MD
, MD
The following individuals have reported the listed relevant financial relationships with commercial interests related to the content of this educational activity.
P RESENTER N AME N AME OF C OMMERCIAL I NTEREST R ELATIONSHIP
X AVIER MARIETTE MD , PHD GSK RESEARCH PROJECT / PHASE 2 OF BELIMUMAB IN SJOGREN
XAVIER MARIETTE , MD , PHD LILLY SPEAKER AT EULAR 2014
Relevant Financial Relationships: Financial relationships are those relationships in which the individual benefits by receiving a salary, royalty, intellectual property rights, consulting fee, honoraria, ownership interest (e.g., stocks, stock options or other ownership interest, excluding diversified mutual funds), or other financial benefit. Financial benefits are usually associated with roles such as employment, management position, independent contractor (including contracted research), consulting, speaking and teaching, membership on advisory committees or review panels, board membership, and other activities from which remuneration is received or expected
D ISCLOSURE OF U NAPPROVED U SES OF P RODUCTS
P RESENTER NAME
XAVIER MARIETTE MD PHD
P RODUCT
BELIMUMAB
:
BENLYSTA
*
I NVESTIGATIONAL AND / OR O FF LABEL U SE
INVESTIGATIONAL AND OFF
-
LABEL IN SJOGREN
’
S SYNDROME
XAVIER MARIETTE MD PHD
XAVIER MARIETTE MD PHD
XAVIER MARIETTE MD PHD
XAVIER MARIETTE MD PHD
TABALUMAB
RITUXIMAB
ABATACEPT
: MABTHERA *
: ORENCIA *
TOCILIZUMAB : RO ACTEMRA *
INVESTIGATIONAL AND OFF LABEL IN SJOGREN ’ S SYNDROME
INVESTIGATIONAL AND OFF LABEL IN SJOGREN ’ S SYNDROME
INVESTIGATIONAL AND OFF LABEL IN SJOGREN ’ S SYNDROME
INVESTIGATIONAL AND OFF LABEL IN SJOGREN ’ S SYNDROME