Practice name Address State, City, Zip Phone: Fax: E-mail: Name: __________________________________________ Date:____________________________ ASA Challenge Angioedema/Urticaria/asthma with or without anaphylaxis The patient needs to avoid H1 antihistamines and Cromolyn. If necessary can treat with steroids for the asthma. There is risk with this procedure as the patient can have hives, respiratory problems, or anaphylaxis. The patient must be watch carefully with serial vital signs and pulmonary function testing Obtain Baseline Spirometry and Final Spirometry unless reduced Peak Flow or respiratory symptoms develop during testing, then repeat more often. Time: 2 ½-3 hours minimum ASA 81 mg. Plan to add 10 cc water and dissolve completely. This makes approximately 10 mg/cc dilution. Then take 1 cc of this preparation and add 9 cc water. This makes a 1 mg/cc solution. Protocol Dose Time Administered Pulse Resp BP Skin exam + any other symptoms, signs Baseline values ASA 1 mg, wait 30 minutes ASA 10 mg, wait 30 min. ASA 81 mg wait 30 minutes ASA 165 mg, ½ of an adult 325 mg tablet 30 minutes ASA 325 mg tablet, wait 45 minutes Notes:----------------------------------------------------------------------------------------------- ------------------ Final Diagnosis:__________________________________________________ Directions after discharge:_____________________________________________ Spiro completed list time